Sirtuin-1 (SIRT1) is required for promoting chondrogenic differentiation of mesenchymal stem cells

Journal of Biological Chemistry

Volumn 289, Issue 32, 2014, Pages 22048-22062

  Buhrmann, Constanze ^a   Busch, Franziska ^a   Shayan, Parviz ^b,c   Shakibaei, Mehdi ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b Investigating Institute of Molecular Biological System Transfer   (Iran)

^c UNIVERSITY OF TEHRAN   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLATION; CARTILAGE; ENZYME INHIBITION;

CHONDROGENESIS; CHONDROGENIC DIFFERENTIATION; DEACETYLATION; MESENCHYMAL STEM CELL; MOLECULAR SIGNALING; NUCLEAR FACTORS; UP-REGULATION;

CELL CULTURE;

4(2'-AMINOETHYL)AMINO-1,8-DIMETHYLIMIDAZO(1,2-A)QUINOXALINE; ENZYME INHIBITOR; I KAPPA B KINASE; IMIDAZOLE DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; NICOTINAMIDE; QUINOXALINE DERIVATIVE; RESVERATROL; SIRT1 PROTEIN, HUMAN; SIRTUIN 1; SOX9 PROTEIN, HUMAN; STILBENE DERIVATIVE; TRANSCRIPTION FACTOR SOX9;

ACETYLATION; ANTAGONISTS AND INHIBITORS; CARTILAGE CELL; CELL CULTURE; CELL DIFFERENTIATION; CHONDROGENESIS; CYTOLOGY; DRUG EFFECTS; ENZYME ACTIVATION; GENE SILENCING; GENETICS; HUMAN; MESENCHYMAL STROMA CELL; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ACETYLATION; CELL DIFFERENTIATION; CELLS, CULTURED; CHONDROCYTES; CHONDROGENESIS; ENZYME ACTIVATION; ENZYME INHIBITORS; GENE KNOCKDOWN TECHNIQUES; HUMANS; I-KAPPA B KINASE; IMIDAZOLES; INTERLEUKIN-1BETA; MESENCHYMAL STROMAL CELLS; NF-KAPPA B; NIACINAMIDE; QUINOXALINES; SIGNAL TRANSDUCTION; SIRTUIN 1; SOX9 TRANSCRIPTION FACTOR; STILBENES;

EID: 84905822021     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.568790     Document Type: Article

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