Liver X receptor agonist prevents LPS-induced mastitis in mice

International Immunopharmacology

Volumn 22, Issue 2, 2014, Pages 379-383

  Fu, Yunhe ^a   Tian, Yuan ^a   Wei, Zhengkai ^a   Liu, Hui ^b   Song, Xiaojing ^a   Liu, Wenbo ^b   Zhang, Wenlong ^a   Wang, Wei ^a   Cao, Yongguo ^a   Zhang, Naisheng ^a  

^a JILIN UNIVERSITY   (China)

^b Daqing Honggang District Animal Health Supervision   (China)

Author keywords

LXR ; Mastitis; Myeloperoxidase; Nuclear factor kappaB (NF B)

Indexed keywords

ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; CYTOKINE; FLUORINATED HYDROCARBON; I KAPPA B; LIPOPOLYSACCHARIDE; LIVER X RECEPTOR; NF-KAPPAB INHIBITOR ALPHA; ORPHAN NUCLEAR RECEPTOR; PEROXIDASE; PROSTAGLANDIN E2; PTGS2 PROTEIN, MOUSE; SULFONAMIDE; TO-901317; TRANSCRIPTION FACTOR RELA;

AGONISTS; ANIMAL; BAGG ALBINO MOUSE; CHEMICALLY INDUCED; DRUG EFFECTS; FEMALE; IMMUNOLOGY; MASTITIS; PATHOLOGY; UDDER;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CYCLOOXYGENASE 2; CYTOKINES; DINOPROSTONE; FEMALE; HYDROCARBONS, FLUORINATED; I-KAPPA B PROTEINS; LIPOPOLYSACCHARIDES; MAMMARY GLANDS, ANIMAL; MASTITIS; MICE, INBRED BALB C; ORPHAN NUCLEAR RECEPTORS; PEROXIDASE; SULFONAMIDES; TRANSCRIPTION FACTOR RELA;

EID: 84905738923     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2014.07.015     Document Type: Article

References (39)

1. F.J. DeGraves, and J. Fetrow Economics of mastitis and mastitis control Vet Clin North Am Food Anim Pract 9 1993 421 434
2. W.N. Philpot Economics of mastitis control Vet Clin North Am Large Anim Pract 6 1984 233 245
3. M. Rinaldi, R.W. Li, and A.V. Capuco Mastitis associated transcriptomic disruptions in cattle Vet Immunol Immunopathol 138 2010 267 279
4. J.L. Watts Etiological agents of bovine mastitis Vet Microbiol 16 1988 41 66
5. S. Schmitz, M.W. Pfaffl, H.H. Meyer, and R.M. Bruckmaier Short-term changes of mRNA expression of various inflammatory factors and milk proteins in mammary tissue during LPS-induced mastitis Domest Anim Endocrinol 26 2004 111 126 (Pubitemid 38192786)
6. J.P. Konsman, P. Parnet, and R. Dantzer Cytokine-induced sickness behaviour: mechanisms and implications Trends Neurosci 25 2002 154 159 (Pubitemid 34164341)
7. J.W. Browning, G.A. Mein, P. Brightling, T.J. Nicholls, and M. Barton Strategies for mastitis control: dry cow therapy and culling Aust Vet J 71 1994 179 181
8. K. Sakurai, S. Fujisaki, K. Enomoto, S. Amano, and M. Sugitani Evaluation of follow-up strategies for corticosteroid therapy of idiopathic granulomatous mastitis Surg Today 41 2011 333 337
9. S. McDougall, K.I. Parker, C. Heuer, and C.W. Compton A review of prevention and control of heifer mastitis via non-antibiotic strategies Vet Microbiol 134 2009 177 185
10. W.C. Sim, S. Park, K.Y. Lee, Y.T. Je, H.Q. Yin, and Y.J. Choi et al. LXR-alpha antagonist meso-dihydroguaiaretic acid attenuates high-fat diet-induced nonalcoholic fatty liver Biochem Pharmacol 90 2014 414 424
11. M. van der Stoep, Z.S. Li, L. Calpe-Berdiel, R.J. van der Sluis, P. Saleh, and H.J. McKinnon et al. Elimination of macrophages drives LXR-induced regression both in initial and advanced stages of atherosclerotic lesion development Biochem Pharmacol 86 2013 1594 1602
12. S. Ducheix, A. Montagner, V. Theodorou, L. Ferrier, and H. Guillou The liver X receptor: a master regulator of the gut-liver axis and a target for non alcoholic fatty liver disease Biochem Pharmacol 86 2013 96 105
13. P.A. Edwards, H.R. Kast, and A.M. Anisfeld BAREing it all: the adoption of LXR and FXR and their roles in lipid homeostasis J Lipid Res 43 2002 2 12 (Pubitemid 34117211)
14. M. Ishibashi, R. Filomenko, C. Rebe, A. Chevriaux, A. Varin, and V. Derangere et al. Knock-down of the oxysterol receptor LXRalpha impairs cholesterol efflux in human primary macrophages: lack of compensation by LXRbeta activation Biochem Pharmacol 86 2013 122 129
15. D.W. Russell Nuclear orphan receptors control cholesterol catabolism Cell 97 1999 539 542 (Pubitemid 29256955)
16. O. Mani, M.T. Sorensen, K. Sejrsen, R.M. Bruckmaier, and C. Albrecht Differential expression and localization of lipid transporters in the bovine mammary gland during the pregnancy-lactation cycle J Dairy Sci 92 2009 3744 3756
17. J.W. McFadden, and B.A. Corl Activation of liver X receptor (LXR) enhances de novo fatty acid synthesis in bovine mammary epithelial cells J Dairy Sci 93 2010 4651 4658
18. C. Oppi-Williams, J.K. Suagee, and B.A. Corl Regulation of lipid synthesis by liver X receptor alpha and sterol regulatory element-binding protein 1 in mammary epithelial cells J Dairy Sci 96 2013 112 121
19. A. Archer, E. Stolarczyk, M.L. Doria, L. Helguero, R. Domingues, and J.K. Howard et al. LXR activation by GW3965 alters fat tissue distribution and adipose tissue inflammation in ob/ob female mice J Lipid Res 54 2013 1300 1311
20. B. Dong, C.F. Kan, A.B. Singh, and J. Liu High-fructose diet downregulates long-chain acyl-CoA synthetase 3 expression in liver of hamsters via impairing LXR/RXR signaling pathway J Lipid Res 54 2013 1241 1254
21. W. Cui, Y. Sun, Z. Wang, C. Xu, Y. Peng, and R. Li Liver X receptor activation attenuates inflammatory response and protects cholinergic neurons in App/Ps1 transgenic mice Neuroscience 210 2012 200 210
22. D.M. Wang, M.M. Liu, Y.S. Wang, M. Luo, J.Z. Wang, and C.Z. Dai et al. Synthetic LXR agonist T0901317 attenuates lipopolysaccharide-induced acute lung injury in rats Int Immunopharmacol 11 2011 2098 2103
23. C. Hindinger, D.R. Hinton, S.J. Kirwin, R.D. Atkinson, M.E. Burnett, and C.C. Bergmann et al. Liver X receptor activation decreases the severity of experimental autoimmune encephalomyelitis J Neurosci Res 84 2006 1225 1234 (Pubitemid 44654446)
24. S.R. Chintalacharuvu, G.E. Sandusky, T.P. Burris, and S. Nagpal Liver X receptor is a therapeutic target in collagen-induced arthritis Arthritis Rheum 56 2007 1365 1367 (Pubitemid 46608662)
25. A.J. Fowler, M.Y. Sheu, M. Schmuth, J. Kao, J.W. Fluhr, and L. Rhein et al. Liver X receptor activators display anti-inflammatory activity in irritant and allergic contact dermatitis models: liver-X-receptor-specific inhibition of inflammation and primary cytokine production J Invest Dermatol 120 2003 246 255 (Pubitemid 36513075)
26. C. Gabbi, H.J. Kim, K. Hultenby, D. Bouton, G. Toresson, and M. Warner et al. Pancreatic exocrine insufficiency in LXR beta(-/-) mice is associated with a reduction in aquaporin-1 expression Proc Natl Acad Sci U S A 105 2008 15052 15057
27. K.N. Maxwell, R.E. Soccio, E.M. Duncan, E. Schayek, and J.L. Breslow Novel putative SREBP and LXR target genes identified by microarray analysis in liver of cholesterol-fed mice J Lipid Res 44 2003 2109 2119 (Pubitemid 37509626)
28. C. Crisafulli, E. Mazzon, I. Paterniti, M. Galuppo, P. Bramanti, and S. Cuzzocrea Effects of liver X receptor agonist treatment on signal transduction pathways in acute lung inflammation Respir Res 11 2010
29. J.E. Krawisz, P. Sharon, and W.F. Stenson Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models Gastroenterology 87 1984 1344 1350 (Pubitemid 15201434)
30. Y.H. Zhu, C. Fossum, M. Berg, and U. Magnussona Morphometric analysis of proinflammatory cytokines in mammary glands of sows suggests an association between clinical mastitis and local production of IL-1beta, IL-6 and TNF-alpha Vet Res 38 2007 871 882
31. Y. Fu, E. Zhou, Z. Wei, D. Liang, W. Wang, and T. Wang et al. Glycyrrhizin inhibits the inflammatory response in mouse mammary epithelial cells and a mouse mastitis model FEBS J 281 2014 2543 2557
32. Y. Fu, Z. Wei, E. Zhou, N. Zhang, and Z. Yang Cyanidin-3-O-beta-glucoside inhibits lipopolysaccharide-induced inflammatory response in mouse mastitis model J Lipid Res 55 2014 1111 1119
33. S. Uda, S. Spolitu, F. Angius, M. Collu, S. Accossu, and S. Banni et al. Role of HDL in cholesteryl ester metabolism of lipopolysaccharide-activated P388D1 macrophages J Lipid Res 54 2013 3158 3169
34. H. Liu, X. Wu, Z. Dong, Z. Luo, Z. Zhao, and Y. Xu et al. Fatty acid synthase causes drug resistance by inhibiting TNF-alpha and ceramide production J Lipid Res 54 2013 776 785
35. E.D. Tang, C.Y. Wang, Y. Xiong, and K.L. Guan A role for NF-kappaB essential modifier/IkappaB kinase-gamma (NEMO/IKKgamma) ubiquitination in the activation of the IkappaB kinase complex by tumor necrosis factor-alpha J Biol Chem 278 2003 37297 37305 (Pubitemid 37175246)
36. M. Yang, L. Cao, M. Xie, Y. Yu, R. Kang, and L. Yang et al. Chloroquine inhibits HMGB1 inflammatory signaling and protects mice from lethal sepsis Biochem Pharmacol 86 2013 410 418
37. K.C. McGrath, X.H. Li, P.T. Whitworth, R. Kasz, J.T. Tan, and S.V. McLennan et al. High density lipoproteins improve insulin sensitivity in high-fat diet-fed mice by suppressing hepatic inflammation J Lipid Res 55 2014 421 430
38. Z. Zhao, X. Tang, X. Zhao, M. Zhang, W. Zhang, and S. Hou et al. Tylvalosin exhibits anti-inflammatory property and attenuates acute lung injury in different models possibly through suppression of NF-kappaB activation Biochem Pharmacol 90 2014 73 87
39. L. Wang, Y. Xu, Q. Yu, Q. Sun, Y. Xu, and Q. Gu et al. H-RN, a novel antiangiogenic peptide derived from hepatocyte growth factor inhibits inflammation in vitro and in vivo through PI3K/AKT/IKK/NF-kappaB signal pathway Biochem Pharmacol 89 2014 255 265