Elimination of macrophages drives LXR-induced regression both in initial and advanced stages of atherosclerotic lesion development

Biochemical Pharmacology

Volumn 86, Issue 11, 2013, Pages 1594-1602

  Van Der Stoep, Marco ^a,b   Li, Zhaosha ^a   Calpe Berdiel, Laura ^a   Van Der Sluis, Ronald J ^a   Saleh, Peshtiwan ^a   McKinnon, Heather J ^c   Smit, Martin J ^c   Korporaal, Suzanne J A ^a,b   Van Berkel, Theo J C ^a   Van Eck, Miranda ^a   Hoekstra, Menno ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Atherosclerosis; Bone marrow transplantation; Liver X receptor; Regression; T0901317

Indexed keywords

ABC TRANSPORTER A1; ABC TRANSPORTER G1; APOLIPOPROTEIN A1; APOLIPOPROTEIN B; APOLIPOPROTEIN E; BETA ACTIN; CD68 ANTIGEN; CHOLIC ACID; FAS ANTIGEN; HIGH DENSITY LIPOPROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; LIVER X RECEPTOR; LOW DENSITY LIPOPROTEIN RECEPTOR; N (2,2,2 TRIFLUOROETHYL) N [4 (2,2,2 TRIFLUORO 1 HYDROXY 1 TRIFLUOROMETHYLETHYL)PHENYL]BENZENESULFONAMIDE; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ROOT; ARTICLE; ATHEROGENESIS; ATHEROSCLEROTIC PLAQUE; BONE MARROW TRANSPLANTATION; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIET SUPPLEMENTATION; HYPERLIPIDEMIA; LIPID DIET; LIPOPROTEIN BLOOD LEVEL; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ATHEROSCLEROSIS; BONE MARROW TRANSPLANTATION; LIVER X RECEPTOR; REGRESSION; T0901317;

ANIMALS; APOLIPOPROTEINS E; BONE MARROW TRANSPLANTATION; CELL COUNT; CHOLESTEROL, VLDL; DIET; DISEASE MODELS, ANIMAL; FEMALE; HYDROCARBONS, FLUORINATED; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; ORPHAN NUCLEAR RECEPTORS; PLAQUE, ATHEROSCLEROTIC; RECEPTORS, LDL; SEVERITY OF ILLNESS INDEX; SULFONAMIDES; TRIGLYCERIDES;

EID: 84887424874     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2013.09.019     Document Type: Article

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