Testing models of the APC tumor suppressor/β-catenin interaction reshapes our view of the destruction complex in Wnt signaling

Genetics

Volumn 197, Issue 4, 2014, Pages 1285-1302

  Yamulla, Robert J ^a   Kane, Eric G ^a   Moody, Alexandra E ^a   Politi, Kristin A ^a   Lock, Nicole E ^a   Foley, Andrew V A ^a   Roberts, David M ^a  

^a FRANKLIN AND MARSHALL COLLEGE   (United States)

Author keywords

Adenomatous polyposis coli (APC); Axin destruction complex; Colon cancer; Wnt signaling; catenin

Indexed keywords

APC PROTEIN; BETA CATENIN; APC2 PROTEIN, DROSOPHILA; DROSOPHILA PROTEIN; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; BINDING SITE; CELL FATE; CONTROLLED STUDY; DELETION MUTANT; DROSOPHILA; EMBRYO; GENE EXPRESSION; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION INITIATION; WNT SIGNALING PATHWAY; ANIMAL; CHEMICAL STRUCTURE; COLON POLYPOSIS; EMBRYOLOGY; FEMALE; GENE DELETION; GENE EXPRESSION REGULATION; GENETICS; MALE; METABOLISM; PHOSPHORYLATION; TUMOR CELL LINE;

ADENOMATOUS POLYPOSIS COLI; ANIMALS; BETA CATENIN; CELL LINE, TUMOR; DROSOPHILA; DROSOPHILA PROTEINS; FEMALE; GENE DELETION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MODELS, MOLECULAR; PHOSPHORYLATION; TUMOR SUPPRESSOR PROTEINS; WNT SIGNALING PATHWAY;

EID: 84905666093     PISSN: 00166731     EISSN: 19432631     Source Type: Journal    
DOI: 10.1534/genetics.114.166496     Document Type: Article

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