Upregulation of immunoproteasome subunits in myositis indicates active inflammation with involvement of antigen presenting cells, CD8 T-cells and IFNγ

PLoS ONE

Volumn 9, Issue 8, 2014, Pages

  Ghannam, Khetam ^a   Martinez Gamboa, Lorena ^a   Spengler, Lydia ^a   Krause, Sabine ^b   Smiljanovic, Biljana ^a   Bonin, Marc ^a   Bhattarai, Salyan ^a   Grützkau, Andreas ^c   Burmester, Gerd R ^a   Häupl, Thomas ^a   Feist, Eugen ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c German Arthritis Research Center   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERFERON REGULATORY FACTOR 1; PROTEASOME; PROTEASOME SUBUNIT BETA TYPE 10; PROTEASOME SUBUNIT BETA TYPE 5; PROTEASOME SUBUNIT BETA TYPE 6; PROTEASOME SUBUNIT BETA TYPE 7; PROTEASOME SUBUNIT BETA TYPE 8; PROTEASOME SUBUNIT BETA TYPE 9; STAT1 PROTEIN; UNCLASSIFIED DRUG; IFNG PROTEIN, HUMAN; IRF1 PROTEIN, HUMAN; MUSCLE PROTEIN; STAT1 PROTEIN, HUMAN;

ADULT; AGED; ANTIGEN PRESENTATION; ARTICLE; CD8+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MARKER GENE; MOLECULAR PATHOLOGY; MONOCYTE; MYOSITIS; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; BIOSYNTHESIS; CLINICAL TRIAL; COMPARATIVE STUDY; ENZYMOLOGY; GENE EXPRESSION REGULATION; IMMUNOLOGY; METABOLISM; MIDDLE AGED; PATHOLOGY;

ADULT; AGED; CD8-POSITIVE T-LYMPHOCYTES; DENDRITIC CELLS; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INTERFERON REGULATORY FACTOR-1; INTERFERON-GAMMA; MALE; MIDDLE AGED; MUSCLE PROTEINS; MYOSITIS; PROTEASOME ENDOPEPTIDASE COMPLEX; STAT1 TRANSCRIPTION FACTOR; UP-REGULATION;

EID: 84905484334     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0104048     Document Type: Article

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