A critical role for the inducible proteasomal subunits LMP7 and MECL1 in cytokine production by activated murine splenocytes

Pharmacology

Volumn 89, Issue 3-4, 2012, Pages 117-126

  Rockwell, Cheryl E ^a   Monaco, John J ^b   Qureshi, Nilofer ^c  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF MISSOURI KANSAS CITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cytokines; GATA3; LMP7; MECL1; Proteasomes; Splenocytes

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 2 RECEPTOR BETA; INTERLEUKIN 4; IONOMYCIN; LACTACYSTIN; LOW MOLECULAR MASS PROTEIN 7; MESSENGER RNA; MULTICATALYTIC ENDOPEPTIDASE COMPLEX LIKE 1 PROTEIN; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEASOME; STAT1 PROTEIN; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET; TRANSCRIPTION FACTOR YY1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SUBUNIT; SIGNAL TRANSDUCTION; SPLEEN CELL; TH1 CELL; TH2 CELL; WILD TYPE;

ANIMALS; CYSTEINE ENDOPEPTIDASES; CYTOKINES; GATA3 TRANSCRIPTION FACTOR; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTEASOME ENDOPEPTIDASE COMPLEX; RNA, MESSENGER; SPLEEN; T-BOX DOMAIN PROTEINS;

EID: 84857754073     PISSN: 00317012     EISSN: 14230313     Source Type: Journal    
DOI: 10.1159/000336335     Document Type: Article

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