Inclusion body myositis: Laser microdissection reveals differential Up-regulation of IFN-γ signaling cascade in attacked versus nonattacked myofibers

American Journal of Pathology

Volumn 179, Issue 3, 2011, Pages 1347-1359

  Ivanidze, Jana ^a,b   Hoffmann, Reinhard ^c   Lochmller, Hanns ^d   Engel, Andrew G ^e   Hohlfeld, Reinhard ^a,b   Dornmair, Klaus ^a,b  

^a UNIVERSITY OF MUNICH   (Germany)

^b MAX PLANCK INSTITUTE OF NEUROBIOLOGY   (Germany)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^d NEWCASTLE UNIVERSITY   (United Kingdom)

^e MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; GAMMA INTERFERON RECEPTOR 1; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE (NADP); HLA A ANTIGEN; HLA ANTIGEN CLASS 1; HLA B ANTIGEN; HLA C ANTIGEN; HLA DP ANTIGEN; HLA DQA1 ANTIGEN; HLA DQB1 ANTIGEN; HLA DR ANTIGEN; HLA E ANTIGEN; HLA F ANTIGEN; HLA G ANTIGEN; INTERFERON GAMMA RECEPTOR 2; PROTEASOME; RANTES; STAT1 PROTEIN; STAT3 PROTEIN; UNCLASSIFIED DRUG;

AGED; ANTIGEN EXPRESSION; ARTICLE; ATTACKED MYOFIBER; CD8+ T LYMPHOCYTE; CELL HYBRIDIZATION; CELL ISOLATION; CLINICAL ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; INCLUSION BODY MYOSITIS; LASER MICRODISSECTION; MALE; MICROARRAY ANALYSIS; MUSCLE BIOPSY; MUSCLE CELL; NONATTACKED MYOFIBER; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

AGED; CASE-CONTROL STUDIES; FEMALE; HLA ANTIGENS; HUMANS; INTERFERON-GAMMA; LASER THERAPY; MALE; MICRODISSECTION; MIDDLE AGED; MUSCLE FIBERS, SKELETAL; MUSCLE, SKELETAL; MYOSITIS, INCLUSION BODY; RECEPTORS, INTERFERON; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 80052854800     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2011.05.055     Document Type: Article

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