HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis

Nature

Volumn 502, Issue 7471, 2013, Pages 381-384

  Adelman, Carrie A ^a   Lolo, Rafal L ^a   Birkbak, Nicolai J ^b   Murina, Olga ^c   Matsuzaki, Kenichiro ^a   Horejsi, Zuzana ^a   Parmar, Kalindi ^d   Borel, Valérie ^a   Skehel, J Mark ^a   Stamp, Gordon ^e   D'Andrea, Alan ^d   Sartori, Alessandro A ^c   Swanton, Charles ^a,f   Boulton, Simon J ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^c UNIVERSITY OF ZURICH   (Switzerland)

^d DANA FARBER CANCER INSTITUTE   (United States)

^e MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^f UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

FANCONI ANEMIA PROTEIN; HELICASE; HELQ HELICASE; RAD51 PROTEIN; UNCLASSIFIED DRUG;

ANEMIA; DNA; GERM CELL; PHENOTYPE; RECOMBINATION; TUMOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CARCINOGENESIS; CELL LOSS; CONTROLLED STUDY; DNA REPAIR; EMBRYO; EMBRYONIC STEM CELL; FANCONI ANEMIA; FEMALE; FEMALE SUBFERTILITY; FIBROBLAST; GENE REPLICATION; GENE SILENCING; GERM CELL; HAPLOINSUFFICIENCY; HISTOLOGY; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; MASS SPECTROMETRY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; PROTEOMICS; PULSED FIELD GEL ELECTROPHORESIS; SERTOLI CELL; SURVIVAL; TESTIS WEIGHT; WESTERN BLOTTING;

ANIMALS; CARCINOGENESIS; DNA DAMAGE; DNA HELICASES; DNA REPAIR; DNA REPLICATION; FANCONI ANEMIA; FANCONI ANEMIA COMPLEMENTATION GROUP D2 PROTEIN; FEMALE; GENE DELETION; GERM CELLS; MALE; MICE; MULTIPROTEIN COMPLEXES; OVARIAN NEOPLASMS; OVARY; RAD51 RECOMBINASE; RECOMBINATIONAL DNA REPAIR;

CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER; MAMMALIA; MUS;

EID: 84885870096     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature12565     Document Type: Article

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