The role of abscisic acid in fruit ripening and responses to abiotic stress

Journal of Experimental Botany

Volumn 65, Issue 16, 2014, Pages 4577-4588

  Leng, Ping ^a   Yuan, Bing ^b   Guo, Yangdong ^a   Chen, Pei ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

^b University of Arizona   (United States)

Author keywords

ABA; ABA metabolism; ABA signalling; ABA transporter; fruit ripening; stress response; transcriptional regulation

Indexed keywords

ABSCISIC ACID;

FRUIT; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PHYSIOLOGICAL STRESS; SIGNAL TRANSDUCTION; TRANSPORT AT THE CELLULAR LEVEL;

ABSCISIC ACID; BIOLOGICAL TRANSPORT; FRUIT; METABOLIC NETWORKS AND PATHWAYS; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL;

EID: 84905457513     PISSN: 00220957     EISSN: 14602431     Source Type: Journal    
DOI: 10.1093/jxb/eru204     Document Type: Review

References (169)

1. Abeles FB, Morgan PW, Saltveit ME. 1992. Ethylene in plant biology. New York: Academic Press.
2. Alexander L, Grierson D. 2002. Ethylene biosynthesis and action in tomato: A model for climacteric fruit ripening. Journal of Experimental Botany 53, 2039-2055.
3. Alvaro S, Ruiz KB, Ravaglia D, Costa G, Torrigiani P. 2013. ABA may promote or delay peach fruit ripening through modulation of ripening-and hormone-related gene expression depending on the developmental stage. Plant Physiology and Biochemistry 64, 11-24.
4. Antoni R, Rodriguez L, Gonzalez-Guzman M, Pizzio GA, Rodriguez PL. 2011. News on ABA transport, protein degradation, and ABFs/WRKYs in ABA signaling. Current Opinion in Plant Biology 14, 547-553.
5. Archbold DD, Dennis FG Jr. 1984. Quantification of free ABA and free and conjugated IAA in strawberry achene and receptacle tissue during fruit development. Journal of the American Society for Horticultural Science 109, 330-335.
6. Ban T, Ishimaru M, Kobayashi S, Shiozaki S, Goto-Yamamoto N, Horiuchi S. 2003. Abscisic acid and 2,4-dichlorophenoxyacetic acid affect the expression of anthycyanin biosynthesic pathway genes in 'Kyoho' grape berries. Journal of Horticultural Science and Biotechnology 78, 586-589.
7. Barry C. 2010. Factors influencing the ripening and quality of fleshy fruits. Annual Plant Reviews 38, 296-326.
8. Berli FJ, Fanzone M, Piccoli P, Bottini R. 2011. Solar UV-B and ABA are involved in phenol metabolism of Vitis vinifera L. Increasing biosynthesis of berry skin polyphenols. Journal of Agriculural and Food Chemistry 59, 4874-4884.
9. Bino RJ, Ric de Vos CH, Lieberman M, Hall RD, Bovy A, Jonker HH, Tikunov Y, Lommen A, Moco S, Levin I. 2005. The lighthyperresponsive high pigment-2dg mutation of tomato: Alterations in the fruit metabolome. New Phytologist 166, 427-438.
10. Bleecker AB, Kende H. 2000. Ethylene: A gaseous signal molecule in plants. Annual Review of Cell and Developmental Biology 16, 1-18.
11. Boursiac Y, Leran S, Corratge-Faillie C, Gojon A, Krouk G, Lacombe B. 2013. ABA transport and transporters. Trends in Plant Science 18, 325-333.
12. Brummell DA, Harpster MH, Dunsmuir P. 1999. Differential expression of expansin gene family members during growth and ripening of tomato fruit. Plant Molecular Biology 39, 161-169.
13. Brzobohaty B, Moore I, Kristoffersen P, Bako L, Campos N, Schell J, Palme K. 1993. Release of active cytokinin by a beta-glucosidase localized to the maize root meristem. Science 262, 1051-1054.
14. Buesa C, Dominguez M, Vendrell M. 1994. Abscisic acid effects on ethylene production and respiration rate in detached apple fruits at different stages of development. Revista Espanola de Cienciay y Tecnologia de Alimentos 34, 495-506.
15. Burbidge A, Grieve TM, Jackson A, Thompson A, McCarty DR, Taylor IB. 1999. Characterization of the ABA-deficient tomato mutant notabilis and its relationship with maize Vp14. The Plant Journal 17, 427-431.
16. Burla B, Pfrunder S, Nagy R, Francisco RM, Lee Y, Martinoia E. 2013. Vacuolar transport of abscisic acid glucosyl ester is mediated by ATP-binding cassette and proton-antiport mechanisms in Arabidopsis. Plant Physiology 163, 1446-1458.
17. Cakir B, Agasse A, Gaillard C, Saumonneau A, Delrot S, Atanassova R. 2003. A grape ASR protein involved in sugar and abscisic acid signaling. The Plant Cell 15, 2165-2180.
18. Carpita NC, Gibeaut DM. 1993. Structural models of primary cell walls in flowering plants: Consistency of molecular structure with the physical properties of the walls during growth. The Plant Journal 3, 1-30.
19. Cheng WH, Endo A, Zhou L, et al. 2002. A unique short-chain dehydrogenase/reductase in Arabidopsis glucose signalling and abscisic acid biosynthesis and functions. The Plant Cell 14, 2723-2743.
20. Chernys JT, Zeevaart JAD. 2000. Characterization of the 9-cisepoxycarotenoid dioxygenase gene family and the regulation of abscisic acid biosynthesis in avocado. Plant Physiology 124, 343-354.
21. Choi H, Hong J, Ha J, Kang J, Kim SY. 2000. ABFs, a family of ABA responsive element binding factors. Journal of Biological Chemistry 275, 1723-1730.
22. Chung MY, Vrebalov J, Alba R, Lee J, McQuinn R, Chung JD, Klein P, Giovannoni J. 2010. A tomato (Solanum lycopersicum) APETALA2/ERF gene, SlAP2a, is a negative regulator of fruit ripening. The Plant Journal 64, 936-947.
23. Cosgrove DJ. 2000. Expansive growth of plant cell walls. Plant Physiology and Biochemistry 38, 109-124.
24. Dekkers BJW, Schuurmans JAMJ, Smeekens SCM. 2004. Glucose delays seed germination in Arabidopsis thaliana. Planta 218, 579-588.
25. DellaPenna D, Pogson BJ. 2006. Vitamin synthesis in plants: Tocopherols and carotenoids. Annual Review of Plant Biology 57, 711-738.
26. Deluc LG, Grimplet J, Wheatley MD, Tillett RL, Quilici DR, Osborne C, Schooley DA, Schlauch KA, Cushman JC, Cramer GR. 2007. Transcriptomic and metabolite analyses of Cabernet Sauvignon grape berry development. BMC Genomics 8, 429.
27. Deluc LG, Quilici DR, Decendit A, Grimplet J, Wheatley MD, Schlauch KA, Merillon JM, Cushman JC, Cramer GR. 2009. Water deficit alters differentially metabolic pathways affecting important flavor and quality traits in grape berries of Cabernet Sauvignon and Chardonnay. BMC Genomics 10, 212.
28. Deytieux C, Geny L, Lapaillerie D, Claverol S, Bonneu M, Doneche B. 2007. Proteome analysis of grape skins during ripening. Journal Experimental Botany 58, 1851-1862.
29. Eccher G, Ferrerob S, Populina F, Colombob L, Botton A. 2014. Apple (Malus domestica L. Borkh) as an emerging model for fruit development. Plant Biosystems 148, doi. org/10.1080/11263504.2013.870254
30. Else MA, Stankiewicz-Davies AP, Crisp CM, Atkinson CJ. 2004. The role of polar auxin transport through pedicels of Prunus avium L. in relation to fruit development and retention. Journal of Experimental Botany 55, 2099-2109.
31. Endo A, Sawada Y, Takahashi H, et al. 2008. Drought induction of Arabidopsis 9-cis-epoxycarotenoid dioxygenase occurs in vascular parenchyma cells. Plant Physiology 147, 1984-1993.
32. Estevez JM, Cantero A, Reindl A, Reichler S, Leon P. 2001. 1-Deoxyd-xylulose-5-phosphate synthase, a limiting enzyme for plastidic isoprenoid biosynthesis in plants. Journal of Biological Chemistry 276, 22901-22909.
33. Feng YM, Wei XK, Liao WX, Huang LH, Zhang H, Liang SC, Peng H. 2013. Molecular analysis of the annexin gene family in soybean. Biologia Plantarum 57, 655-662.
34. Finkelstein RR, Gibson SI. 2001. ABA and sugar interactions regulating development: Cross-talk or voices in a crowd? Current Opinion in Plant Biology 5, 26-32.
35. Fraser PD, Romer S, Shipton CA, Mills PB, Kiano JW, Misawa N, Drake RG, Schuch W, Bramley PM. 2002. Evaluation of transgenic tomato plants expression an additional phytoene synthase in a fruit-specific manner. Proceedings of the National Academy of Sciences, USA 99, 1092-1097.
36. Frey A, Audran C, Marin E, Sotta B, Marion-Poll A. 1999. Engineering seed dormancy by the modification of zeaxanthin epoxidase gene expression. Plant Molecular Biology 39, 1267-1274.
37. Fujita Y, Nakashima K, Yoshida T, et al. 2009. Three SnRK2 protein kinases are the main positive regulators of abscisic acid signaling in response to water stress in Arabidopsis. Plant and Cell Physiology 50, 2123-2132.
38. Galpaz N, Wang Q, Menda N, Zamir D, Hirschberg J. 2008. Abscisic acid deficiency in the tomato mutant high-pigment 3 leading to increased plastid number and higher fruit lycopene content. The Plant Journal 53, 717-730.
39. Gambetta GA, Matthews MA, Shaghasi TH, McElrone AJ, Castellarin SD. 2010. Sugar and abscisic acid signaling orthologs are activated at the onset of ripening in grape. Planta 232, 219-234.
40. Gazzarrini S, McCourt P. 2001. Genetic interactions between ABA, ethylene and sugar signaling pathways. Current Opinion in Plant Biology 4, 387-391.
41. Giovannoni J. 2001. Molecular biology of fruit maturation and ripening. Annual Review of Plant Physiology and Plant Molecular Biology 52, 725-749.
42. Giovannoni JJ. 2004. Genetic regulation of fruit development and ripening. The Plant Cell 16, S170-S180.
43. Giovannoni JJ. 2007. Fruit ripening mutants yield insights into ripening control. Current Opinion in Plant Biology 10, 283-289.
44. Giribaldi M, Gény L, Delrot S, Schubert A. 2010. Proteomic analysis of the effects of ABA treatments on ripening Vitis vinifera berries. Journal of Experimental Botany 61, 2447-2458.
45. Gómez-Porras JL, Riaño-Pachón DM, Dreyer I, Mayer JE, Mueller-Roeber B. 2007. Genome-wide analysis of ABA-responsive elements ABRE and CE3 reveals divergent patterns in Arabidopsis and rice. BMC Genomics 8, 260-273.
46. Gonzalez-Ballester D, Pollock SV, Pootakham W, Grossman AR. 2008. The central role of a SNRK2 kinase in sulfur deprivation responses. Plant Physiology 147, 216-227.
47. Gonzalez-Guzman M, Pizzio GA, Antoni R et al. 2012. Arabidopsis PYR/PYL/RCAR receptors play a major role in quantitative regulation of stomatal aperture and transcriptional response to abscisic acid. The Plant Cell 24, 2483-2496.
48. Hartung W, Sauter A, Hose E. 2002. Abscisic acid in the xylem: Where does it come from, where does it go to? Journal of Experimental Botany 53, 27-32.
49. Hattori T, Totsuka M, Hobo T, Kagaya Y, Yamamoto-Toyoda A. 2002. Experimentally determined sequence requirement of ACGT-containing abscisic acid response element. Plant and Cell Physiology 43, 136-140.
50. Hiwasa K, Kinugasa Y, Amano S, Hashimoto A, Nakano R, Inaba A, Kubo Y. 2003. Ethylene is required for both the initiation and progression of softening in pear (Pyrus communis L.) fruit. Journal of Experimental Botany 54, 771-779.
51. Huber DJ. 1983. Polyuronide degradation and hemicellulose modification in ripening tomato fruit. Journal of the American Society for Horticultural Science 108, 405-409.
52. Huo H, Dahal P, Kunusoth K, McCallum CM, Bradford KJ. 2013. Expression of 9-cis-EPOXYCAROTENOID DIOXYGENASE4 is essential for thermoinhibition of lettuce seed germination but not for seed development or stress tolerance. The Plant Cell 25, 884-900.
53. Itkin M, Seybold H, Breitel D, Rogachev I, Meir S, Aharoni A. 2009. TOMATO AGAMOUS-LIKE 1 is a component of the fruit ripening regulatory network. The Plant Journal 60, 1081-1095.
54. Iuchi S, Kobayashi M, Taji T, Naramoto M, Seki M, Kato T, Tabata S, Kakubari Y, Yamaguchi-Shinozaki K, Shinozaki K. 2001. Regulation of drought tolerance by gene manipulation of 9-cis-epoxycarotenoid dioxygenase, a key enzyme in abscisic acid biosynthesis in Arabidopsis. The Plant Journal 27, 325-333.
55. Jaakola L, Poole M, Jones MO, et al. 2010. A SQUAMOSA MADS box gene involved in the regulation of anthocyanin accumulation in bilberry fruits. Plant Physiology 153, 1619-1629.
56. Jeong ST, Goto-Yamamoto N, Kobayashi S, Esaka M. 2004. Effects of plant hormones and shading on the accumulation of anthocyanins and the expression of anthocyanin biosynthetic genes in grape berry skins. Plant Science 167, 247-252.
57. Ji K, Chen P, Sun L, et al. 2012. Non-climacteric ripening in strawberry fruit is linked to ABA, FaNCED2 and FaCYP707A1. Functional Plant Biology 39, 351-357.
58. Jia HF, Chai YM, Li CL, Lu D, Luo JJ, Qin L, Shen YY. 2011. Abscisic acid plays an important role in the regulation of strawberry fruit ripening. Plant Physiology 157, 188-199.
59. Jia HF, Wang YH, Sun MZ, et al. 2013. Sucrose functions as a signal involved in the regulation of strawberry fruit development and ripening. New Phytologist 198, 453-465.
60. Jiang F, Hartung W. 2008. Long-distance signaling of abscisic acid (ABA): The factors regulating the intensity of the ABA signal. Journal of Experimental Botany 59, 37-43.
61. Kachanovsky DE, Filler S, Isaacson T, Hirschberg J. 2012. Epistasis in tomato color mutations involves regulation of phytoene synthase 1 expression by cis-carotenoids. Proceedings of the National Academy of Sciences, USA 109, 19021-19026.
62. Kang JY, Choi HI, Im MY, Kim SY. 2002. Arabidopsis basic leucine zipper proteins that mediate stress-responsive abscisic acid signaling. The Plant Cell 14, 343-357.
63. Karlova R, Rosin FM, Busscher-Lange J, Parapunova V, Do PT, Fernie AR, Fraser PD, Baxter C, Angenent GC, de Maagd RA. 2011. Transcriptome and metabolite profiling show that APETALA2a is a major regulator of tomato fruit ripening. The Plant Cell 23, 923-941.
64. Karppinen K, Hirvelä E, Nevala T, Sipari N, Suokas M, Jaakola L. 2013. Changes in the abscisic acid levels and related gene expression during fruit development and ripening in bilberry (Vaccinium myrtillus L.). Phytochemistry 95, 127-134.
65. Klee HJ, Giovannoni JJ. 2011. Genetics and control of tomato fruit ripening and quality attributes. Annual Review of Genetics 45, 41-59.
66. Klingler JP, Batelli G, Zhu JK. 2010. ABA receptors: The START of a new paradigm in phytohormone signalling. Journal of Experimental Botany 61, 3199-3210.
67. Kojima K, Yamada Y, Yamamoto M. 1995. Effects of abscisic acid injection on sugar and organic acid contents of citrus fruit. Japanese Society for Horticultural Science 64, 17-21.
68. Koiwai H, Nakaminami K, Seo M, Mitsuhashi W, Toyomasu T, Koshiba T. 2004. Tissue-specific localization of an abscisic acid biosynthetic enzyme, AAO3, in Arabidopsis. Plant Physiology 134, 1697-1707.
69. Kolotilin I, Koltai H, Tadmor Y, Bar-Or C, Reuveni M, Meir A, Nahon S, Shlomo H, Chen L, Levin I. 2007. Transcriptional profiling of high pigment-2dg tomato mutant links early fruit plastid biogenesis with its overproduction of phytonutrients. Plant Physiology 145, 389-401.
70. Kondo S, Inoue K. 1997. Abscisic acid (ABA) and 1-aminocyclopropane-1- carboxylic acid (ACC) content during growth of 'Satonishiki' cherry fruit, and the effect of ABA and ethephon application on fruit quality. Journal of Horticultural Science 72, 221-227.
71. Koyama K, Sadamatsu K, Goto-Yamamoto N. 2010. Abscisic acid stimulated ripening and gene expression in berry skins of the Cabernet Sauvignon grape. Functional and Integrative Genomics 10, 367-381.
72. Kushiro T, Okamoto M, Nakabayashi K, Yamagishi K, Kitamura S, Asami T, Hirai N, Koshiba T, Kamiya Y, Nambara E. 2004. The Arabidopsis cytochrome P450 CYP707A encodes ABA 8'-hydroxylases: Key enzymes in ABA catabolism. The EMBO Journal 23, 1647-1656.
73. Lacampagne S, Gagne S, Geny L. 2009. Involvement of abscisic acid in controlling the proanthocyanidin biosynthesis pathway in grape skin: New elements regarding the regulation of tannin composition and leucoanthocyanidin reductase (LAR) and anthocyanidin reductase (ANR) activities and expression. Journal of Plant Growth Regulation 29, 81-90.
74. Lara I, Vendrell M. 2000. Changes in abscisic acid levels, ethylene biosynthesis, and protein patterns during fruit maturation of 'Granny Smith' apples. Journal of the American Society for Horticultural Science 125, 183-189.
75. Lashbrook CC, Gonzalez-Bosch C, Bennett AB. 1994. Two divergent endo-beta-1,4-glucanase genes exhibit overlapping expression in ripening fruit and abscising flowers. The Plant Cell 6, 1485-1493.
76. Lee JM, Joung JG, McQuinn R, Chung MY, Fei ZJ, Tieman D, Klee H, Giovannoni J. 2012. Combined transcriptome, genetic diversity and metabolite profiling in tomato fruit reveals that the ethylene response factor SlERF6 plays an important role in ripening and carotenoid accumulation. The Plant Journal 70, 191-204.
77. Lee KH, Piao HL, Kim HY, Choi SM, Jiang F, Hartung W, Hwang I, Kwak JM, Lee IJ, Hwang I. 2006. Activation of glucosidase via stressinduced polymerization rapidly increases active pools of abscisic acid. Cell 126, 1109-1120.
78. Leng P, Zhang GL, Li XX, Wang LH, Zheng ZM. 2009. Cloning of 9-cisepoxycarotenoid dioxygenase (NCED) gene encoding a key enzyme during abscisic acid (ABA) biosynthesis and ABA-regulated ethylene production in detached young calyx. Chinese Science Bulletin 54, 2830-2838.
79. Li Q, Ji K, Sun YF, Luo H, Wang HQ, Leng P. 2013. The role of FaBG3 in fruit ripening and B. cinerea fungal infection of strawberry. The Plant Journal 76, 24-35.
80. Lindgren LO, Stalberg KG, Hoglund AS. 2003. Seed-specific overexpression of an endogenous Arabidopsis phytoene synthase gene results in delayed germination and increased levels of carotenoids, chlorophyll, and abscisic acid. Plant Physiology 132, 968-981.
81. Liu XD, Zhang H, Zhao Y, Feng ZY, Li Q, Yang HQ, Luan S, Li JM, He ZH. 2013. Auxin controls seed dormancy through stimulation of abscisic acid signaling by inducing ARF-mediated ABI3 activation in Arabidopsis. Proceedings of the National Academy of Sciences, USA 110, 15485-15490.
82. Liu XG, Yue YL, Li B, Nie YL, Li W, Wu WH, Ma LG. 2007. A G proteincoupled receptor is a plasma membrane receptor for the plant hormone abscisic acid. Science 315, 1712-1716.
83. Lovisetto A, Guzzo F, Tadiello A, Confortin E, Pavanello A, Botton A, Casadoro G. 2013. Characterization of a bZIP gene highly expressed during ripening of the peach fruit. Plant Physiology and Biochemistry 70, 462-470
84. Luo H, Dai SJ, Ren J, et al. 2013. The role of ABA in the maturation and postharvest life of a nonclimacteric sweet cherry fruit. Journal of Plant Growth Regulation doi: 10.1007/s00344-013-9388-7.
85. Ma Y, Szostkiewicz I, Korte A, Moes D, Yang Y, Christmann A, Grill E. 2009. Regulators of PP2C phosphatase activity function as abscisic acid sensors. Science 324, 1064-1068.
86. Manning K, Tör M, Poole M, Hong YG, Thompson AJ, King GJ, Giovannoni JJ, Seymour GB. 2006. A naturally occurring epigenetic mutation in a gene encoding an SBP-box transcription factor inhibits tomato fruit ripening. Nature Genetics 38, 948-952.
87. Martel C, Vrebalov J, Tafelmeyer P, Giovannoni JJ. 2011. The tomato MADS-box transcription factor RIPENING INHIBITOR interacts with promoters involved in numerous ripening processes in a COLORLESS NONRIPENING-dependent manner. Plant Physiology 157, 1568-1579.
88. Matas AJ, Yeats TH, Buda GJ, et al. 2011. Tissue-and cell-type specific transcriptome profiling of expanding tomato fruit provides insights into metabolic and regulatory specialization and cuticle formation. The Plant Cell 23, 3893-3910.
89. Medina-Puche L, Cumplido-Laso G, Amil-Ruiz F, Hoffmann T, Ring L, Rodríguez-Franco A, Caballero JL, Schwab W, Muñoz-Blanco J, Blanco-Portales R. 2013. MYB10 plays a major role in the regulation of flavonoid/phenylpropanoid metabolism during ripening of Fragaria ×ananassa fruits. Journal of Experimental Botany 65, 401-417.
90. Melcher K, Ng LM, Zhou XE, et al. 2009. A gate-latch-lock mechanism for hormone signalling by abscisic acid receptors. Nature 462, 602-608.
91. Mittelheuser CJ, van Steveninck RFM. 1969. Stomatal closure and inhibition of transpiration induced by (RS)-abscisic acid. Nature 221, 281-282.
92. Mochizuki N, Brusslan JA, Larkin R, Nagatani A, Chory J. 2001. Arabidopsis genomes uncoupled 5 (GUN5) mutant reveals the involvement of Mg-chelatase H subunit in plastid-to-nucleus signal transduction. Proceedings of the National Academy of Sciences, USA 98, 2053-2058.
93. Muller AH, Hansson M. 2009. The barley magnesium chelatase 150-kD subunit is not an abscisic acid receptor. Plant Physiology 150, 157-166.
94. Nakano R, Ogura E, Kubo Y, Inaba A. 2003. Ethylene biosynthesis in detached young persimmon fruit is initiated in calyx and modulated by water loss from the fruit. Plant Physiology 131, 276-286.
95. Nicolas P, Lecourieux D, Kappel C, Cluzet S, Cramer G, Delrot S, Lecourieux F. 2014. The basic leucine zipper transcription factor ABSCISIC ACID RESPONSE ELEMENT-BINDING FACTOR2 is an important transcriptional regulator of abscisic acid-dependent grape berry ripening processes. Plant Physiology 164, 365-383.
96. Nijhawan A, Jain M, Tyagi AK, Khurana JP. 2008. Genomic survey and gene expression analysis of the basic leucine zipper transcription factor family in rice. Plant Physiology 146, 333-350
97. Nishimura N, Hitomi K, Arvai AS, Rambo RP, Hitomi C, Cutler SR, Schroeder JI, Getzoff ED. 2009. Structural mechanism of abscisic acid binding and signaling by dimeric PYR1. Science 326, 1373-1379.
98. Nishiyama K, Guis M, Rose JKC, et al. 2007. Ethylene regulation of fruit softening and cell wall disassembly in Charentais melon. Journal of Experimental Botany 58, 1281-1290.
99. Nitsch LMC, Oplaat C, Feron R, Ma Q, Wolters-Arts M, Hedden P, Mariani C, Vriezen WH. 2009. Abscisic acid levels in tomato ovaries are regulated by LeNCED1 and SlCYP707A1. Planta 229. 1335-1346.
100. North HM, De Almeida A, Boutin JP, Frey A, To A, Botran L, Sotta B, Marion-Poll A. 2007. The Arabidopsis ABA-deficient mutant aba4 demonstrates that the major route for stress-induced ABA accumulation is via neoxanthin isomers. The Plant Journal 50, 810-824.
101. Pandy S, Nelson DC, Assmann SM. 2009. Two novel GPCR-type G proteins are abscisic acid receptors in Arabidopsis. Cell 136, 136-148.
102. Park SY, Fung P, Nishimura N, et al. 2009. Abscisic acid inhibits type 2C protein phosphatases via the PYR/PYL family of START proteins. Science 324, 1068-1071.
103. Pons C, Martí C, Forment J, Crisosto CH, Dandekar AM, Granell A. 2014. A bulk segregant gene expression analysis of a peach population reveals components of the underlying mechanism of the fruit cold response. PLoS One 9, e90706.
104. Price J, Li TC, Kang SG, Na JK, Jang JC. 2003. Mechanisms of glucose signaling during germination of Arabidopsis. Plant Physiology 132, 1424-1438.
105. Qin XQ, Zeevaart JAD. 1999. The 9-cis-epoxycarotenoid cleavage reaction is the key regulatory step of abscisic acid biosynthesis in waterstressed bean. Proceedings of the National Academy of Sciences, USA 96, 15354-15361.
106. Qin XQ, Zeevaart JAD. 2002. Overexpression of a 9-cis-epoxycarotenoid dioxygenase gene in Nicotiana plumbaginifolia increases abscisic acid and phaseic acid levels and enhances drought tolerance. Plant Physiology 128, 544-551.
107. Ren J, Chen P, Dai SJ, Li P, Li Q, Ji K, Wang YP, Leng P. 2011. Role of abscisic acid and ethylene in sweet cherry fruit maturation: Molecular aspects. New Zealand Journal of Crop and Horticultural Science 39, 1-14.
108. Ren J, Sun L, Wu JF, Zhao SL, Wang CL, Wang YP, Ji K, Leng P. 2010. Cloning and expression analysis of cDNAs for ABA 8′-hydroxylase during sweet cherry fruit maturation and under stress conditions. Journal of Plant Physiology 167, 1486-1493.
109. Rodrigo MJ, Alquezar B, Zacarias L. 2006. Cloning and characterization of two 9-cis-epoxycarotenoid dioxygenase genes, differentially regulated during fruit maturation and under stress conditions, from orange (Citrus sinensis L. Osbeck). Journal of Experimental Botany 57, 633-643.
110. Rodrigo MJ, Marcos JF, Alferez F, Mallent MD, Zacarias L. 2003. Characterization of Pinalate, a novel Citrus sinensis mutant with a fruitspecific alteration that results in yellow pigmentation and decreased ABA content. Journal of Experimental Botany 54, 727-738.
111. Rolland F, Baeno-Gonzalez E, Sheen J. 2006. Sugar sensing and signaling in plants: Conserved and novel mechanisms. Annual Review of Plant Biology 57, 675-709.
112. Romero P, Lafuente MT, Rodrigo MJ. 2012. The Citrus ABA signalosome: Identification and transcriptional regulation during sweet orange fruit ripening and leaf dehydration. Journal of Experimental Botany 63, 4931-4945.
113. Saito S, Hirai N, Matsumoto C, Ohigashi H, Ohta D, Sakata K, Mizutani M. 2004. Arabidopsis CYP707As encode (+)-abscisic acid 8'-hydroxylase, a key enzyme in the oxidative catabolism of abscisic acid. Plant Physiology 134, 1439-1449.
114. Saladie M, Matas AJ, Isaacson T, et al. 2007. A reevaluation of the key factors that influence tomato fruit softening and integrity. Plant Physiology 144, 1012-1028.
115. Santiago J, Dupeux F, Round A, Antoni R, Park SY, Jamin M, Cutler SR, Rodriguez PL, Marquez JA. 2009. The abscisic acid receptor PYR1 in complex with abscisic acid. Nature 462, 665-668.
116. Sauter A, Dietz KJ, Hartung W. 2002. A possible stress physiological role of abscisic acid conjugates in root-to-shoot signaling. Plant, Cell and Environment 25, 223-228.
117. Schwartz SH, Qin XQ, Zeevaart JAD. 2003. Elucidation of the indirect pathway of abscisic acid biosynthesis by mutants, genes, and enzymes. Plant Physiology 131, 1591-1601.
118. Schweighofer A, Hirt H, Meskiene I. 2004. Plant PP2C phosphatases: Emerging functions in stress signaling. Trends in Plant Science 9, 236-243.
119. Seo M, Koshiba T. 2002. Complex regulation of ABA biosynthesis in plants. Trends in Plant Science 7, 41-48.
120. Seo M, Koshiba T. 2011. Transport of ABA from the site of biosynthesis to the site of action. Journal of Plant Research 124, 501-507.
121. Seki M, Umezawa T, Urano K, Shinozaki K. 2007. Regulatory metabolic networks in drought stress responses. Current Opinion in Plant Biology 10, 296-302.
122. Setha S, Kondo S, Hirai N, Ohigashi H. 2005. Quanti?cation of ABA and its metabolites in sweet cherries using deuterium-labeled internal standards. Plant Growth Regulation 45, 183-188.
123. Seymour GB, Chapman NH, Chew BL, Rose JKC. 2013a. Regulation of ripening and opportunities for control in tomato and other fruits. Plant Biotechnology Journal 11, 269-278.
124. Seymour GB, Ostergaard L, Chapman NH, Knapp S, Martin C. 2013b. Fruit development and ripening. Annual Review of Plant Biology 64, 219-241.
125. Seymour G, Poole M, Manning K, King GJ. 2008. Genetics and epigenetics of fruit development and ripening. Current Opinion in Plant Biology 11. 58-63.
126. Shang Y, Yan L, Liu ZQ, et al. 2010. The Mg-chelatase H subunit of Arabidopsis antagonizes a group of WRKY transcription repressors to relieve ABA-responsive genes of inhibition. The Plant Cell 22, 1909-1935.
127. Shen XJ, Zhao K, Liu LL, Zhang KC, Huazhao Yuan HZ, Liao X, Wang Q, Xinwei Guo XW, Li F, Li TH. 2014. A role for PacMYBA in ABA-regulated anthocyanin biosynthesis in red-colored sweet cherry cv. Hong Deng (Prunus avium L.). Plant and Cell Physiology (in press).
128. Shen YY, Wang XF, Wu FQ, et al. 2006. The Mg-chelatase H subunit is an abscisic acid receptor. Nature 443, 823-826.
129. Smeekens S. 2000. Sugar-induced signal transduction in plants. Annual Review of Plant Physiology and Plant Molecular Biology 51, 49-81.
130. Smith DL, Gross KC. 2000. A family of at least seven β-galactosidase genes is expressed during tomato fruit development. Plant Physiology 123, 1173-1184.
131. Srivastava A, Handa AK. 2005. Hormonal regulation of tomato fruit development: A molecular perspective. Journal of Plant Growth Regulation 24, 67-82.
132. Sun L, Sun YF, Zhang M, et al. 2012a. Suppression of 9-cisepoxycarotenoid dioxygenase, which encodes a key enzyme in abscisic acid biosynthesis, alters fruit texture in transgenic tomatoes. Plant Physiology 158, 283-298.
133. Sun L, Wang YP, Chen P, Ren J, Ji K, Li Q, Li P, Dai SJ, Leng P. 2011. Transcriptional regulation of SlPYL, SlPP2C and SlSnRK2 gene families encoding ABA signal core components during tomato fruit development and drought stress. Journal of Experimental Botany 62, 5659-5669.
134. Sun L, Yuan B, Zhang M, Wang L, Cui MM, Wang Q, Leng P. 2012b. Fruit-specific RNAi-mediated suppression of SlNCED1 increases both lycopene and β-carotene contents in tomato fruit. Journal of Experimental Botany 63, 3097-3108.
135. Sun L, Zhang M, Ren J, Qi JX, Zhang GJ, Leng P. 2010. Reciprocity between abscisic acid and ethylene at the onset of berry ripening and after harvest. BMC Plant Biology 10, 257.
136. Sun YF, Chen P, Duan CR, et al. 2013. Transcriptional regulation of genes encoding key enzymes of abscisic acid metabolism during melon (Cucumis melo L.) fruit development and ripening. Journal of Plant Growth Regulation 32, 233-244.
137. Takata M. 1983. Respiration, ethylene production and ripening of Japanese persimmon fruit harvested at various stages of development. Journal of the Japanese Society for Horticultural Science 52, 78-84.
138. Tan BC, Cline K, McCarty DR. 2001. Localization and targeting of the VP14 epoxy-carotenoid dioxygenase to chloroplast membranes. The Plant Journal 27, 373-382.
139. Tan BC, Schwartz SH, Zeevaart JAD, McCarty DR. 1997. Genetic control of abscisic acid biosynthesis in maize. Proceedings of the National Academy of Sciences, USA 94, 12235-12240.
140. Taylor IB, Burbidge A, Thompson AJ. 2000. Control of abscisic acid synthesis. Journal of Experimental Botany 51, 1563-1574.
141. Taylor IB, Sonneveld T, Bugg TDH, Thompson AJ. 2005. Regulation and manipulation of the biosynthesis of abscisic acid, including the supply of xanthophyll precursors. Journal of Plant Growth Regulation 24, 253-273.
142. Thompson AJ, Jackson AC, Symonds RC, Mulholland BJ, Dadswell AR, Blake PS, Burbidge A, Taylor IB. 2000. Ectopic expression of a tomato 9-cis-epoxycarotenoid dioxygenase gene causes over-production of abscisic acid. The Plant Journal 23, 363-374.
143. Tieman DM, Harriman RW, Ramamohan G, Handa AK. 1992. An antisense pectin methylesterase gene alters pectin chemistry and soluble solids in tomato fruit. The Plant Cell 4, 667-679.
144. Tigchelaar EC, Mcglasson WB, Franklin MJ. 1978. Natural and ethephon-stimulated ripening of F1 hybrids of the ripening inhibitor (rin) and non-ripening (nor) mutants of tomato (Lycopersicon esculentum Mill.). Australian Journal of Plant Physiology 5, 449-456.
145. Tikunov YM, Molthoff J, de Vos RCH, et al. 2013. NON-SMOKY GLYCOSYLTRANSFERASE1 prevents the release of smoky aroma from tomato fruit. The Plant Cell 25, 3067-3078.
146. Tonetto de Freitas S, McElrone AJ, Shackel KA, Mitcham EJ. 2014. Calcium partitioning and allocation and blossom-end rot development in tomato plants in response to whole-plant and fruit-specific abscisic acid treatments. Journal of Experimental Botany 65, 235-247.
147. Trainotti L, Pavanello A, Casadoro G. 2005. Different ethylene receptors show an increased expression during the ripening of strawberries: Does such an increment imply a role for ethylene in the ripening of these non-climacteric fruits? Journal of Experimental Botany 56, 2037-2046.
148. Tung SA, Smeeton R, White C, Black CR, Taylor IB, Hilton HW, Thompson AJ. 2008. Over-expression of LeNCED1 in tomato (Solanum lycopersicum L.) with the rbcS3C promoter allows recovery of lines that accumulate very high levels of abscisic acid and exhibit severe phenotypes. Plant, Cell and Environment 31, 968-981.
149. Umezawa T, Okamoto M, Kushiro T, Nambara E, Oono Y, Seki M, Kobayashi M, Koshiba T, Kamiya Y, Shinozaki K. 2006. CYP707A3, a major ABA 8'-hydroxylase involved in dehydration and rehydration response in Arabidopsis thaliana. The Plant Journal 46, 171-182.
150. Vrebalov J, Ruezinsky D, Padmanabhan V, White R, Medrano D, Drake R, Schuch W, Giovannoni J. 2002. A MADS-box gene necessary for fruit ripening at the tomato ripening-inhibitor (rin) locus. Science 296, 343-346.
151. Wang YP, Wang Y, Ji K, et al. 2013. The role of abscisic acid in regulating cucumber fruit development and ripening and its transcriptional regulation. Plant Physiology and Biochemistry 64, 70-79.
152. Wang YP, Wu Y, Duan CR, et al. 2012. The expression profiling of the CsPYL, CsPP2C and CsSnRK2 gene families during fruit development and drought stress in cucumber. Journal of Plant Physiology 169, 1874-1882.
153. Wheeler S, Loveys B, Ford C, Davies C. 2009. The relationship between the expression of abscisic acid biosynthesis genes, accumulation of abscisic acid and the promotion of Vitis vinifera L. berry ripening by abscisic acid. Australian Journal of Grape and Wine Research 15, 195-204.
154. White PJ. 2002. Recent advances in fruit development and ripening: An overview. Journal of Experimental Botany 53, 1995-2000.
155. Wright STC, Hiron RWP. 1969. (+)-Abscisic acid, the growth inhibitor induced in detached wheat leaves by a period of wilting. Nature 224, 719-720.
156. Wu FQ, Xin Q, Cao Z, et al. 2009. The magnesium-chelatase H subunit binds abscisic acid and functions in abscisic acid signaling: New evidence in Arabidopsis. Plant Physiology 150, 1940-1954.
157. Xu ZY, Lee KH, Dong T, et al. 2012. A vacuolar β-glucosidase homolog
158. Yamaki S, Asakura T. 1991. Stimulation of the uptake of sorbitol into vacuoles from apple fruit flesh by abscisic acid and into protoplasts by indoleacetic acid. Plant and Cell Physiology 32, 315-318.
159. Yen HC, Shelton BA, Howard LR, Lee S, Vrebalov J, Giovannoni JJ. 1997. The tomato high-pigment (hp) locus maps to chromosome 2 and influences plastome copy number and fruit quality. Theoretical and Applied Genetics 95, 1069-1079.
160. Yin P, Fan H, Hao Q, Yuan XQ, Wu D, Pang YX, Yan CY, Li WQ, Wang JW, Yan N. 2009. Structural insights into the mechanism of abscisic acid signaling by PYL proteins. Nature Structural and Molecular Biology 16, 1230-1236.
161. Yoshida T, Fujita Y, Sayama H, Kidokoro S, Maruyama K, Mizoi J, Shinozaki K, Yamaguchi-Shinozaki K. 2010. AREB1, AREB2, and ABF3 are master transcription factors that cooperatively regulate ABREdependent ABA signaling involved in drought stress tolerance and require ABA for full activation. The Plant Journal 61, 672-685.
162. Yubero-Serrano EM, Moyano E, Medina-Escobar N, oz-Blanco JM, Caballero JA. 2003. Identication of a strawberry gene encoding a non-specic lipid transfer protein that responds to ABA, wounding and cold stress. Journal of Experimental Botany 54, 1865-1877.
163. Zaharah SS, Singh Z, Symons GM, Reid JB. 2013. Mode of action of abscisic acid in triggering ethylene biosynthesis and softening during ripening in mango fruit. Postharvest Biology and Technology 75, 37-44.
164. Zhang GJ, Duan CR, Wang Y, et al. 2013. The expression pattern of b-glucosidase genes (VvBGs) during grape berry maturation and dehydration stress. Plant Growth Regulation 70, 105-114.
165. Zhang M, Leng P, Zhang GL, Li XX. 2009b. Cloning and functional analysis of 9-cis-epoxycarotenoid dioxygenase (NCED) genes encoding a key enzyme during abscisic acid biosynthesis from peach and grape fruits. Journal of Plant Physiology 166, 1241-1252.
166. Zhang M, Yuan B, Leng P. 2009a. The role of ABA in triggering ethylene biosynthesis and ripening of tomato fruit. Journal of Experimental Botany 60, 1579-1588.
167. Zhao SL, Qi JX, Duan CR, Sun L, Sun YF, Wang YP, Ji K, Chen P, Dai SJ, Leng P. 2012. Expression analysis of the DkNCED1, DkNCED2 and DkCYP707A1 genes that regulate homeostasis of abscisic acid during the maturation of persimmon fruit. Journal of Horticultural Science and Biotechnology 87, 165-171.
168. Zhenga Y, Schumakerc KS, Guo Y. 2012. Sumoylation of transcription factor MYB30 by the small ubiquitin-like modifier E3 ligase SIZ1 mediates abscisic acid response in Arabidopsis thaliana. Proceedings of the National Academy of Sciences, USA 109, 12822-12827.
169. Zhu GH, Liu YG, Ye NH, Liu R, Zhang JH. 2011. Involvement of the abscisic acid catabolic gene CYP707A2 in the glucose-induced delay in seed germination and post-germination growth of Arabidopsis. Physiologia Plantarum 143, 375-384.