Neuroprotective and anti-apoptotic propensity of Bacopa monniera extract against sodium nitroprusside induced activation of iNOS, heat shock proteins and apoptotic markers in PC12 cells

Neurochemical Research

Volumn 39, Issue 5, 2014, Pages 800-814

  Pandareesh, M D ^a   Anand, T ^a  

^a DEFENCE FOOD RESEARCH LABORATORY   (India)

Author keywords

Apoptosis; Bacopa monniera; Inducible nitric oxide synthase (iNOS); Nitric oxide; PC12 cells; Sodium nitroprusside

Indexed keywords

BACOPA MONNIERI EXTRACT; BRAIN DERIVED NEUROTROPHIC FACTOR; CASPASE 3; CYTOCHROME C; FLAVONOID; GLUTATHIONE; HEAT SHOCK PROTEIN 70; HEME OXYGENASE 1; INDUCIBLE NITRIC OXIDE SYNTHASE; MALONALDEHYDE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITROPRUSSIDE SODIUM; PEROXYNITRITE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; NOS2 PROTEIN, RAT; PLANT EXTRACT;

ANIMAL CELL; ANIMAL CELL CULTURE; APOPTOSIS; ARTICLE; CELL DEATH; CELL FRACTIONATION; CELL MEMBRANE; CELL SURVIVAL; CELL VIABILITY ASSAY; COMET ASSAY; CONTROLLED STUDY; CYTOSOLIC FRACTION; DNA DAMAGE; DNA SYNTHESIS; DOWN REGULATION; ENZYME ACTIVATION; LIPID PEROXIDATION; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL MEMBRANE POTENTIAL; MTT ASSAY; NERVE CELL LESION; NEUROPROTECTION; NITRATIVE STRESS; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PC12 CELL LINE; PHYTOCHEMISTRY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; UPREGULATION; WESTERN BLOTTING; WHOLE CELL; ANIMAL; ANTAGONISTS AND INHIBITORS; BACOPA; CHEMISTRY; DRUG EFFECTS;

BACOPA MONNIERI;

ANIMALS; APOPTOSIS; BACOPA; DOWN-REGULATION; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE TYPE II; NITROPRUSSIDE; OXIDATIVE STRESS; PC12 CELLS; PLANT EXTRACTS; RATS;

EID: 84905403831     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-014-1273-7     Document Type: Article

References (49)

1. Wink DA, Osawa Y, Darbyshire JF, Jones CR, Eshenaur SC, Nims RW (1993) Inhibition of cytochromes-P450 by nitric oxide and a nitric oxide-releasing agent. Arch Biochem Biophys 300:115-123 (Pubitemid 23225725)
2. Davis KL, Martin E, Turko IV, Murad F (2001) Novel effects of nitric oxide. Annu Rev Pharmacol Toxicol 41:203-236 (Pubitemid 32385888)
3. Briviba K, Klotz LO, Sies H (1999) Defenses against peroxynitrite. Methods Enzymol 301:391-411
4. Aoyama K, Matsubara K, Fujikawa Y, Nagahiro Y, Shimizu K, Umegae N, Hayase N, Shiono H, Kobayashi S (2000) Nitration of manganese superoxide dismutase in cerebrospinal fluids is a marker for peroxynitrite-mediated oxidative stress in neurodegenerative diseases. Ann Neurol 47:524-527 (Pubitemid 30194612)
5. Chung KK, Dawson TM, Dawson VL (2005) Nitric oxide, S-nitrosylation and neurodegeneration. Cell Mol Biol 51:247-254 (Pubitemid 43093376)
6. Russo A, Borrelli F (2005) Bacopa monniera, a reputed nootropic plant: an overview. Phytomed 12:305-317 (Pubitemid 40471030)
7. Dash VB, Kashyap VL (1980) Materia medica of Ayurveda. Concept Publishing Company, New Delhi, pp 53-54
8. Singh HK, Dhawan BN (1997) Neuropsychopharmacological effects of the Ayurvedic nootropic Bacopa monniera Linn. (Brahmi). Ind J Pharmacol 29:359-365
9. Anand T, Naika Mahadeva, Swamy MSL, Khanum Farhath (2011) Antioxidant and DNA damage preventive properties of Bacopa monniera (L.) Wettst. Free Radic Antioxid 1:84-90
10. Tripathi YB, Chaurasia S, Tripathi E, Upadhyay A, Dubey GP (1996) Bacopa monniera Linn. as an antioxidant: mechanism of action. Ind J Exp Biol 34:523-526
11. Anand T, Phani Kumar G, Pandareesh MD, Swamy MSL, Khanum F, Bawa AS (2012) Effect of bacoside extract from Bacopa monniera on physical fatigue induced by forced swimming. Phytother Res 26:587-593
12. Channa S, Dar A, Anjum S, Yaqoob M, Rahman A (2006) Antiinflammatory activity of Bacopa monniera in rodents. J Ethnopharmacol 104:286-289 (Pubitemid 43234118)
13. Pandareesh MD, Anand T (2013) Neuromodulatory propensity of Bacopa monniera against Scopolamine-induced cytotoxicity in PC12 cells via down regulation of AChE and up regulation of BDNF and muscarnic 1 receptor expression. Cell Mol Neurobiol 33:875-884
14. Anand T, Bhanu Prakash K, Pandareesh MD, Farhath Khanum (2013). Development of bacoside enriched date syrup juice and its evaluation for physical endurance. J Food Sci Technol. doi:10. 1007/s13197-013-0955-5
15. Mark RJ, Keller JN, Kruman I, Mattson MP (1997) Basic FGF attenuates amyloid b-peptide-induced oxidative stress, mitochondrial dysfunction, and impairment of Na+/K+-ATPase activity in hippocampal neurons. Brain Res 756:205-214 (Pubitemid 27241628)
16. Ohkawa H, Ohishi N, Yagi K (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95:351-358 (Pubitemid 9194347)
17. Buege JA, Aust SD (1978) Microsomal lipid peroxidation. Methods Enzymol 52:301-310
18. Singh NP, McCoy MT, Tice RR, Schneider EL (1988) A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res 175:184-191
19. Aebi H (1984) Catalase in vitro. Methods Enzymol 105:121-126
20. Roberta RE, Nicoletta P, Anna P, Ananth P, YangM, Catherine RE (1999) Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radic Biol Med 26:1231-1237 (Pubitemid 29262709)
21. Wang H, Yu S-W, Koh DW, Lew J, Coombos C, Bowers W, Federoff HJ, Poirier GG, Dawson TM, Dawson VL (2004) Apoptosis-Inducing Factor Substitutes For Caspase Executioners in NMDA-triggered excitotoxic neuronal death. J Neurosci 24:10963-10973 (Pubitemid 39602407)
22. Lowry OH, Rosenberg NJ, Farr AL, Randal RJ (1951) Protein measurement with Folin phenol reagent. J Biol Chem 193:265-275
23. Imam SZ, El-Yazal J, Newport GD, Itzhak Y, Cadet JL, Slikker W, Ali SF (2001) Methamphetamine-induced dopaminergic neurotoxicity: role of peroxynitrite and neuroprotective role of antioxidants and peroxynitrite decomposition catalysts. Ann NY Acad Sci 939:366-380 (Pubitemid 32620088)
24. Pytlowany M, Strosznajder JB, Jesko H, Cakala M, Strosznajder RP (2008) Molecular mechanism of PC12 cell death evoked by sodium nitroprusside, a nitric oxide donor. Acta Biochim Pol 55:339-347 (Pubitemid 351947548)
25. Ning N, Jin-feng HU, Yu-he Y, Xin-yuan Z, Jun-gui D, Nai-hong C (2012) Huperzine A derivative M3 protects PC12 cells against sodium nitroprusside-induced apoptosis. Acta Pharmacol Sin 33:34-40
26. Crow JP (1997) Dichlorodihydrofluorescein and dihydrorhodamine 123 are sensitive indicators of peroxynitrite in vitro: implications for intracellular measurement of reactive nitrogen and oxygen species. Nitric Oxide 1:145-157
27. Culmsee C, Gerling N, Landshamer S, Rickerts B, Duchstein HJ, Umezawa K, Klumpp S, Krieglstein J (2005) Nitric oxide donors induce neurotrophin-like survival signaling and protect neurons against apoptosis. Mol Pharmacol 68:1006-1017 (Pubitemid 41345792)
28. Adamczyk A, Czapski GA, KaŸmierczak A, Strosznajder JB (2009) Effect of N-methyl-D-aspartate (NMDA) receptor antagonists on a-synuclein-evoked neuronal nitric oxide synthase activation in the rat brain. Pharmacol Rep 61:1078-1085
29. Motterlini R, Foresti R, Intaglietta M, Winslow RM (1996) NO-mediated activation of heme oxygenase: endogenous cytoprotection against oxidative stress to endothelium. Am J Physiol Heart Circ Physiol 270:107-114
30. Motterlini R, Foresti R, Bassi R, Calabrese V, Clark JE, Green CJ (2000) Endothelial heme oxygenase-1 induction by hypoxia modulation by inducible nitric-oxide synthase and s-nitrosothiols. J Biol Chem 275:13613-13620 (Pubitemid 30257429)
31. Maines MD (1997) The heme oxygenase system: a regulator of second messenger gases. Ann Rev Pharmacol Toxicol 37:517-554
32. Foresti R, Motterlini R (1999) The heme oxygenase pathway and its interaction with nitric oxide in the control of cellular homeostasis. Free Radic Res 31:459-475
33. Murer MG, Yan Q, Raisman-Vozari R (2001) Brain-derived neurotrophic factor in the control human brain, and in Alzheimer's disease and Parkinson's disease. Prog Neurobiol 63:71-124
34. LeBel CP, Ischiropoulos H, Bondy SC (1992) Evaluation of the probe 2′,7′-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress. Chem Res Toxicol 5: 227-231
35. Ly JD, Grubb DR, Lawen A (2003) The mitochondrial membrane potential (Δψm) in apoptosis; an update. Apoptosis 8:115-128 (Pubitemid 36553052)
36. Ubl JJ, Chatton JY, Chen S, Stucki JW (1996) A critical evaluation of in situ measurement of mitochondrial electrical potentials in single hepatocytes. Biochim Biophys Acta 1276:124-132 (Pubitemid 26308728)
37. Hruszkewycz AM (1992) Lipid peroxidation and mtDNA degeneration. A hypothesis. Mutat Res 275:243-248
38. Kim YM, Bergonia H, Lancaster JR (1995) Nitrogen oxide-induced autoprotection in isolated rat hepatocytes. FEBS Lett 374:228-232
39. Fehsel K, Kroncke KD, Meyer KL, Huber H, Wahn V, Kolb-Bachofen V (1995) Nitric oxide induces apoptosis in mouse thymocytes. J Immunol 155:2858-2865
40. Von Knethen A, Callsen D, Brune B (1999) NF-B and AP-1 activation by nitric oxide attenuated apoptotic cell death in RAW 264.7 macrophages. Mol Biol Cell 10:361-372 (Pubitemid 29156478)
41. Kirkinezos IG, Moraes CT (2001) Reactive oxygen species and mitochondrial diseases. Semin Cell Dev Biol 12:449-457
42. Li JL, Wang QY, Luan HY, Kang ZC, Wang CB (2012) Effects of L-carnitine against oxidative stress in human hepatocytes: involvement of peroxisome proliferator-activated receptor alpha. J Biomed Sci 19:32
43. Merad-Boudia M, Nicole A, Santiard-Baron D, Saille C, Ceballos-Picot I (1998) Mitochondrial impairment as an early event in the process of apoptosis induced by glutathione depletion in neuronal cells: relevance to Parkinson's disease. Biochem Pharmacol 56:645-655 (Pubitemid 28458903)
44. Ibi M, Sawada H, Kume T, Katsuki H, Kaneko S, Shimohama S, Akaike A (1999) Depletion of intracellular glutathione increases susceptibility to nitric oxide in mesencephalic dopaminergic neurons. J Neurochem 73:1696-1703 (Pubitemid 29440173)
45. Seif-el-Nasr M, Fahim AT (2001) Antioxidant effect of N omega-nitro-L-arginine methyl ester (L-NAME) on global cerebral ischemia in a rat model. Arzneimittelforschung 51:628-632
46. Sayan H, Ugurlu B, Babul A, Take G, Erdogan D (2004) Effects of L-arginine and NG-nitro L-arginine methyl ester on lipid peroxide, superoxide dismutase and nitrate levels after experimental sciatic nerve ischemia-reperfusion in rats. Int J Neurosci 114:349-364 (Pubitemid 38268779)
47. Awooda HA, Lutfi MF, Sharara GM, Saeed AM (2013) Role of N-Nitro-L-Arginine-Methylester as anti-oxidant in transient cerebral ischemia and reperfusion in rats. Exp Transl Stroke Med 5:1-6
48. Ding-Zhou L, Marchand-Verrecchia C, Croci N, Plotkine M, Margaill I (2002) L-NAME reduces infarction, neurological deficit and blood-brain barrier disruption following cerebral ischemia in mice. Eur J Pharmacol 457:137-146 (Pubitemid 35447655)
49. Rakesh KS, Steven JS, Khan La, Richard H, Edward GL, Dan LL (1999) Bcl-2 and Bcl-XL Block Thapsigargin-Induced Nitric Oxide Generation, c-Jun NH2-Terminal Kinase Activity, and Apoptosis. Mol Cell Biol 19:5659-5674