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Volumn 73, Issue 4, 1999, Pages 1696-1703

Depletion of intracellular glutathione increases susceptibility to nitric oxide in mesencephalic dopaminergic neurons

Author keywords

Dopaminergic neuron; Glutamate; Glutathione; Iron; Nitric oxide

Indexed keywords

ACETYLCYSTEINE; BUTHIONINE SULFOXIMINE; DEFEROXAMINE; GLUTAMIC ACID; GLUTATHIONE; GLUTATHIONE SYNTHASE; IRON; NITRIC OXIDE;

EID: 0032877449     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1999.731696.x     Document Type: Article
Times cited : (51)

References (43)
  • 1
    • 0028580508 scopus 로고
    • Regulation by neuroprotective factors of NMDA receptor mediated nitric oxide synthesis in the brain and retina
    • Akaike A., Tamura Y., Terada K., and Nakata N. (1994) Regulation by neuroprotective factors of NMDA receptor mediated nitric oxide synthesis in the brain and retina. Prog. Brain Res. 103, 391-403.
    • (1994) Prog. Brain Res. , vol.103 , pp. 391-403
    • Akaike, A.1    Tamura, Y.2    Terada, K.3    Nakata, N.4
  • 2
    • 0016652087 scopus 로고
    • Brain peroxidase and catalase in Parkinson's disease
    • Ambani L. M., Van Woert M. H., and Murphy S. (1975) Brain peroxidase and catalase in Parkinson's disease. Arch. Neurol. 32, 114-118.
    • (1975) Arch. Neurol. , vol.32 , pp. 114-118
    • Ambani, L.M.1    Van Woert, M.H.2    Murphy, S.3
  • 3
    • 0000582530 scopus 로고    scopus 로고
    • Revised guide for the care and use of laboratory animals available
    • Bayne K. (1996) Revised guide for the care and use of laboratory animals available. Physiologist 39, 199-208.
    • (1996) Physiologist , vol.39 , pp. 199-208
    • Bayne, K.1
  • 4
    • 0027141376 scopus 로고
    • Aconitase, a two-faced protein: Enzyme and iron regulatory factor
    • Beinert H. and Kennedy M. C. (1993) Aconitase, a two-faced protein: enzyme and iron regulatory factor. FASEB J. 7, 1442-1449.
    • (1993) FASEB J. , vol.7 , pp. 1442-1449
    • Beinert, H.1    Kennedy, M.C.2
  • 5
    • 0026040282 scopus 로고
    • Iron-melanin interaction and lipid peroxidation: Implications for Parkinson's disease
    • Ben-Shachar D., Riederer P., and Youdim M. B. (1991) Iron-melanin interaction and lipid peroxidation: implications for Parkinson's disease. J. Neurochem. 57, 1609-1614.
    • (1991) J. Neurochem. , vol.57 , pp. 1609-1614
    • Ben-Shachar, D.1    Riederer, P.2    Youdim, M.B.3
  • 6
    • 0029012812 scopus 로고
    • Age-and peroxidative stress-related modifications of the cerebral enzymatic activities linked to mitochondria and the glutathione system
    • Benzi G. and Moretti A. (1995) Age-and peroxidative stress-related modifications of the cerebral enzymatic activities linked to mitochondria and the glutathione system. Free Radic. Biol. Med. 19, 77-101.
    • (1995) Free Radic. Biol. Med. , vol.19 , pp. 77-101
    • Benzi, G.1    Moretti, A.2
  • 8
    • 0027476024 scopus 로고
    • A synaptic model of memory: Long-term potentiation in the hippocampus
    • Bliss T. and Collingridge G. L. (1993) A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361, 31-39.
    • (1993) Nature , vol.361 , pp. 31-39
    • Bliss, T.1    Collingridge, G.L.2
  • 9
    • 0024378999 scopus 로고
    • Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum
    • Bredt D. S. and Snyder S. H. (1989) Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum. Proc. Natl. Acad. Sci. USA 86, 9030-9033.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 9030-9033
    • Bredt, D.S.1    Snyder, S.H.2
  • 10
    • 0025622914 scopus 로고
    • Monoamine oxidase and oxidative stress as dopaminergic synapses
    • Cohen G. (1990) Monoamine oxidase and oxidative stress as dopaminergic synapses. J. Neural Transm. Suppl. 32, 229-238.
    • (1990) J. Neural Transm. Suppl. , vol.32 , pp. 229-238
    • Cohen, G.1
  • 11
    • 0025338354 scopus 로고
    • Excitatory amino acid receptors and synaptic plasticity
    • Collingridge G. and Singer W. (1990) Excitatory amino acid receptors and synaptic plasticity. Trends Pharmacol. Sci. 11, 290-296.
    • (1990) Trends Pharmacol. Sci. , vol.11 , pp. 290-296
    • Collingridge, G.1    Singer, W.2
  • 13
    • 0027178135 scopus 로고
    • Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures
    • Dawson V. L., Dawson T. M., Bartley D. A., Uhl G. R., and Snyder S. H. (1993) Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures. J. Neurosci. 13, 2651-2661.
    • (1993) J. Neurosci. , vol.13 , pp. 2651-2661
    • Dawson, V.L.1    Dawson, T.M.2    Bartley, D.A.3    Uhl, G.R.4    Snyder, S.H.5
  • 14
    • 0025821265 scopus 로고
    • Alterations in the levels of iron, ferritin and other trace metals in Parkinson's disease and other neurodegenerative diseases affecting the basal ganglia
    • Dexter D. T., Carayon A., Javoy-Agid F., Agid Y., Wells F. R., Daniel S. E., Lees A. J., Jenner P., and Marsden C. D. (1991) Alterations in the levels of iron, ferritin and other trace metals in Parkinson's disease and other neurodegenerative diseases affecting the basal ganglia. Brain 114, 1953-1975.
    • (1991) Brain , vol.114 , pp. 1953-1975
    • Dexter, D.T.1    Carayon, A.2    Javoy-Agid, F.3    Agid, Y.4    Wells, F.R.5    Daniel, S.E.6    Lees, A.J.7    Jenner, P.8    Marsden, C.D.9
  • 15
    • 0022461970 scopus 로고
    • Murine cytotoxic activated macrophages inhibit aconitase in tumor cells. Inhibition involves the iron-sulfur prosthetic group and is reversible
    • Drapier J. C. and Hibbs J. B. Jr. (1986) Murine cytotoxic activated macrophages inhibit aconitase in tumor cells. Inhibition involves the iron-sulfur prosthetic group and is reversible. J. Clin. Invest. 78, 790-797.
    • (1986) J. Clin. Invest. , vol.78 , pp. 790-797
    • Drapier, J.C.1    Hibbs J.B., Jr.2
  • 16
    • 0027301897 scopus 로고
    • Biosynthesis of nitric oxide activates iron regulatory factor in macrophages
    • Drapier J. C., Hirling H., Wietzerbin J., Kaldy P., and Kuhn L. C. (1993) Biosynthesis of nitric oxide activates iron regulatory factor in macrophages. EMBO J. 12, 3643-3649.
    • (1993) EMBO J. , vol.12 , pp. 3643-3649
    • Drapier, J.C.1    Hirling, H.2    Wietzerbin, J.3    Kaldy, P.4    Kuhn, L.C.5
  • 18
    • 0018095085 scopus 로고
    • Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones
    • Graham D. G. (1978) Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones. Mol. Pharmacol. 14, 633-643.
    • (1978) Mol. Pharmacol. , vol.14 , pp. 633-643
    • Graham, D.G.1
  • 19
    • 0030918062 scopus 로고    scopus 로고
    • Basic fibroblast growth factor stimulation of glial cells protects dopamine neurons from 6-hydroxydopamine toxicity: Involvement of the glutathione system
    • Hou J.-G. G., Cohen G., and Mytilineou C. (1997) Basic fibroblast growth factor stimulation of glial cells protects dopamine neurons from 6-hydroxydopamine toxicity: involvement of the glutathione system. J. Neurochem. 69, 76-83.
    • (1997) J. Neurochem. , vol.69 , pp. 76-83
    • Hou, J.-G.G.1    Cohen, G.2    Mytilineou, C.3
  • 20
    • 0029751104 scopus 로고    scopus 로고
    • Oxidative stress and the pathogenesis of Parkinson's disease
    • Jenner P. and Olanow C. W. (1996) Oxidative stress and the pathogenesis of Parkinson's disease. Neurology 47 (Suppl. 3), S161-S170.
    • (1996) Neurology , vol.47 , Issue.SUPPL. 3
    • Jenner, P.1    Olanow, C.W.2
  • 21
    • 0031031148 scopus 로고    scopus 로고
    • Nitric oxide protects cultured rat hepatocytes from tumor necrosis factor-α-induced apoptosis by inducing heat shock protein 70 expression
    • Kim Y. M., de Vera M. E., Watkins S. C., and Billiar T. R. (1997) Nitric oxide protects cultured rat hepatocytes from tumor necrosis factor-α-induced apoptosis by inducing heat shock protein 70 expression. J. Biol. Chem. 272, 1402-1411.
    • (1997) J. Biol. Chem. , vol.272 , pp. 1402-1411
    • Kim, Y.M.1    De Vera, M.E.2    Watkins, S.C.3    Billiar, T.R.4
  • 22
    • 0027452550 scopus 로고
    • Regulating the fate of mRNA: The control of cellular iron metabolism
    • Klausner R. D., Rouault T. A., and Harford J. B. (1993) Regulating the fate of mRNA: the control of cellular iron metabolism. Cell 72, 19-28.
    • (1993) Cell , vol.72 , pp. 19-28
    • Klausner, R.D.1    Rouault, T.A.2    Harford, J.B.3
  • 23
    • 0029075141 scopus 로고
    • S-nitrosoglutathione improves functional recovery in the isolated rat heart after cardioplegic ischemic arrest - Evidence for a cardioprotective effect of nitric oxide
    • Konorev E. A., Tarpey M. M., Joseph J., Baker J. E., and Kalyanaraman B. (1995) S-Nitrosoglutathione improves functional recovery in the isolated rat heart after cardioplegic ischemic arrest - evidence for a cardioprotective effect of nitric oxide. J. Pharmacol. Exp. Ther. 274, 200-206.
    • (1995) J. Pharmacol. Exp. Ther. , vol.274 , pp. 200-206
    • Konorev, E.A.1    Tarpey, M.M.2    Joseph, J.3    Baker, J.E.4    Kalyanaraman, B.5
  • 24
    • 0027332625 scopus 로고
    • 35S]glutathione binding sites in spinal cords from patients with amyotrophic lateral sclerosis
    • 35S]glutathione binding sites in spinal cords from patients with amyotrophic lateral sclerosis. Neurosci. Lett. 163, 89-92.
    • (1993) Neurosci. Lett. , vol.163 , pp. 89-92
    • Lanius, R.A.1    Krieger, C.2    Wagey, R.3    Shaw, C.A.4
  • 25
    • 0030867994 scopus 로고    scopus 로고
    • A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion
    • Li Y., Maher P., and Schubert D. (1997a) A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion. Neuron 19, 453-463.
    • (1997) Neuron , vol.19 , pp. 453-463
    • Li, Y.1    Maher, P.2    Schubert, D.3
  • 26
    • 0030782430 scopus 로고    scopus 로고
    • Requirement for cGMP in nerve cell death caused by glutathione depletion
    • Li Y., Maher P., and Schubert D. (1997b) Requirement for cGMP in nerve cell death caused by glutathione depletion. J. Cell Biol. 139, 1317-1324.
    • (1997) J. Cell Biol. , vol.139 , pp. 1317-1324
    • Li, Y.1    Maher, P.2    Schubert, D.3
  • 27
    • 0030960327 scopus 로고    scopus 로고
    • Inhibition of the neutral magnesium-dependent sphingomyelinase by glutathione
    • Liu B. and Hannun Y. A. (1997) Inhibition of the neutral magnesium-dependent sphingomyelinase by glutathione. J. Biol. Chem. 272, 16281-16287.
    • (1997) J. Biol. Chem. , vol.272 , pp. 16281-16287
    • Liu, B.1    Hannun, Y.A.2
  • 28
    • 0030779127 scopus 로고    scopus 로고
    • The role of glutathione in dopaminergic neuronal survival
    • Nakamura K., Wang W., and Kang U. J. (1997) The role of glutathione in dopaminergic neuronal survival. J. Neurochem. 69, 1850-1858.
    • (1997) J. Neurochem. , vol.69 , pp. 1850-1858
    • Nakamura, K.1    Wang, W.2    Kang, U.J.3
  • 29
    • 0028929741 scopus 로고
    • Nitric oxide signaling to iron-regulatory protein: Direct control of ferrilin mRNA translation and transferrin receptor mRNA stability in transfected fibroblasts
    • Pantopoulos K. and Hentze M. W. (1995) Nitric oxide signaling to iron-regulatory protein: direct control of ferrilin mRNA translation and transferrin receptor mRNA stability in transfected fibroblasts. Proc. Natl. Acad. Sci. USA 92, 1267-1271.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 1267-1271
    • Pantopoulos, K.1    Hentze, M.W.2
  • 30
    • 0022553605 scopus 로고
    • Idiopathic parkinson's disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patients
    • Perry T. M. and Young W. W. (1986) Idiopathic Parkinson's disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patients. Neurosci. Lett. 67, 269-274.
    • (1986) Neurosci. Lett. , vol.67 , pp. 269-274
    • Perry, T.M.1    Young, W.W.2
  • 31
    • 0024537271 scopus 로고
    • Reduction of brain glutathione by L-buthionine sulfoximine potentiates the dopamine-depleting action of 6-hydroxydopamine in rat striatum
    • Pileblad E., Magnusson T., and Fornstedt B. (1989) Reduction of brain glutathione by L-buthionine sulfoximine potentiates the dopamine-depleting action of 6-hydroxydopamine in rat striatum. J. Neurochem. 52, 978-980.
    • (1989) J. Neurochem. , vol.52 , pp. 978-980
    • Pileblad, E.1    Magnusson, T.2    Fornstedt, B.3
  • 32
    • 0029984860 scopus 로고    scopus 로고
    • Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity
    • Przedborski S., Jackson-Lewis V., Yokoyama R., Shibata T., Dawson V. L., and Dawson T. M. (1996) Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity. Proc. Natl. Acad. Sci. USA 93, 4565-4571.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 4565-4571
    • Przedborski, S.1    Jackson-Lewis, V.2    Yokoyama, R.3    Shibata, T.4    Dawson, V.L.5    Dawson, T.M.6
  • 33
    • 15844413958 scopus 로고    scopus 로고
    • S-nitrosothiols and nitric oxide, but not sodium nitroprusside, protect nigrostriatal dopamine neurons against iron-induced oxidative stress in vivo
    • Rauhala P., Mohanakumar K. P., Sziraki I., Lin A. M., and Chiueh C. C. (1996) S-Nitrosothiols and nitric oxide, but not sodium nitroprusside, protect nigrostriatal dopamine neurons against iron-induced oxidative stress in vivo. Synapse 23, 58-60.
    • (1996) Synapse , vol.23 , pp. 58-60
    • Rauhala, P.1    Mohanakumar, K.P.2    Sziraki, I.3    Lin, A.M.4    Chiueh, C.C.5
  • 34
    • 0031889724 scopus 로고    scopus 로고
    • Neurotprotection by S-nitrosoglutathione of brain dopamine neurons from oxidative stress
    • Rauhala P., Lin A. M., and Chiueh C. C. (1998) Neurotprotection by S-nitrosoglutathione of brain dopamine neurons from oxidative stress. FASEB J. 12, 165-173.
    • (1998) FASEB J. , vol.12 , pp. 165-173
    • Rauhala, P.1    Lin, A.M.2    Chiueh, C.C.3
  • 35
    • 0029876907 scopus 로고    scopus 로고
    • Different mechanisms of glutamate-induced neuronal death between dopaminergic and nondopaminergic neurons in rat mesencephalic culture
    • Sawada H., Kawamura T., Shimohama S., Akaike A., and Kimura J. (1996a) Different mechanisms of glutamate-induced neuronal death between dopaminergic and nondopaminergic neurons in rat mesencephalic culture. J. Neurosci. Res. 43, 503-510.
    • (1996) J. Neurosci. Res. , vol.43 , pp. 503-510
    • Sawada, H.1    Kawamura, T.2    Shimohama, S.3    Akaike, A.4    Kimura, J.5
  • 37
    • 0028075410 scopus 로고
    • Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia
    • Sian J., Dexter D. T., Lees A. J., Daniel S., Agid Y., Javoy-Agid F., Jenner P., and Marsden C. D. (1994) Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia. Ann. Neurol. 36, 348-355.
    • (1994) Ann. Neurol. , vol.36 , pp. 348-355
    • Sian, J.1    Dexter, D.T.2    Lees, A.J.3    Daniel, S.4    Agid, Y.5    Javoy-Agid, F.6    Jenner, P.7    Marsden, C.D.8
  • 38
    • 0026689954 scopus 로고
    • Brain-derived neurotrophic factor protects dopamine neurons against 6-hydroxydopamine and N-methyl-4-phenylpyridinium ion toxicity: Involvement of the glutathione system
    • Spina M. B., Squinto S. P., Miller J., Lindsay R. M., and Hyman C. (1992) Brain-derived neurotrophic factor protects dopamine neurons against 6-hydroxydopamine and N-methyl-4-phenylpyridinium ion toxicity: involvement of the glutathione system. J. Neurochem. 59, 99-106.
    • (1992) J. Neurochem. , vol.59 , pp. 99-106
    • Spina, M.B.1    Squinto, S.P.2    Miller, J.3    Lindsay, R.M.4    Hyman, C.5
  • 39
    • 0025731384 scopus 로고
    • Effect of exogenous and endogenous nitric oxide on mitochondrial respiration of rat hepatocytes
    • Stadler J., Billiar T. R., Curran R. D., Stuehr D. J., Ochoa J. B., and Simmons R. L. (1991) Effect of exogenous and endogenous nitric oxide on mitochondrial respiration of rat hepatocytes. Am. J. Physiol. 260, C910-C916.
    • (1991) Am. J. Physiol. , vol.260
    • Stadler, J.1    Billiar, T.R.2    Curran, R.D.3    Stuehr, D.J.4    Ochoa, J.B.5    Simmons, R.L.6
  • 40
    • 0028956707 scopus 로고
    • Nitric oxide donor compounds inhibit the toxicity of oxidized low-density lipoprotein to endothelial cells
    • Struck A. T., Hogg N., Thomas J. P., and Kalyanaraman B. (1995) Nitric oxide donor compounds inhibit the toxicity of oxidized low-density lipoprotein to endothelial cells. FEBS Lett. 361, 291-294.
    • (1995) FEBS Lett. , vol.361 , pp. 291-294
    • Struck, A.T.1    Hogg, N.2    Thomas, J.P.3    Kalyanaraman, B.4
  • 41
    • 0031025924 scopus 로고    scopus 로고
    • Glutathione depletion in rat brain does not cause nigrostriatal pathway degeneration
    • Toffa S., Kunikowska G. M., Zeng B. Y., Jenner P., and Marsden C. D. (1997) Glutathione depletion in rat brain does not cause nigrostriatal pathway degeneration. J. Neural Transm. 104, 67-75.
    • (1997) J. Neural Transm. , vol.104 , pp. 67-75
    • Toffa, S.1    Kunikowska, G.M.2    Zeng, B.Y.3    Jenner, P.4    Marsden, C.D.5


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