-
1
-
-
33645560785
-
Extracellular matrix in disc degeneration
-
Feng, H., Danfelter, M., Stromqvist, B., and Heinegard, D. (2006) Extracellular matrix in disc degeneration. J. Bone Joint Surg. Am. 88, 25-29
-
(2006)
J. Bone Joint Surg. Am.
, vol.88
, pp. 25-29
-
-
Feng, H.1
Danfelter, M.2
Stromqvist, B.3
Heinegard, D.4
-
2
-
-
33645562104
-
Mechanobiology of the intervertebral disc and relevance to disc degeneration
-
Setton L. A., and Chen, J. (2006) Mechanobiology of the intervertebral disc and relevance to disc degeneration. J. Bone Joint Surg. Am. 88, 52-57
-
(2006)
J. Bone Joint Surg. Am.
, vol.88
, pp. 52-57
-
-
Setton, L.A.1
Chen, J.2
-
3
-
-
0028814521
-
Ingrowth of blood vessels in disc degeneration. Angiographic and histological studies of cadaveric spines
-
Kauppila L. I. (1995) Ingrowth of blood vessels in disc degeneration. Angiographic and histological studies of cadaveric spines. J. Bone Joint Surg. Am. 77, 26-31
-
(1995)
J. Bone Joint Surg. Am.
, vol.77
, pp. 26-31
-
-
Kauppila, L.I.1
-
4
-
-
0035989142
-
Phenotypic characteristics of the nucleus pulposus. Expression of hypoxia inducing factor-1, glucose transporter-1 and MMP-2
-
Rajpurohit, R., Risbud, M. V., Ducheyne, P., Vresilovic, E. J., and Shapiro, I. M. (2002) Phenotypic characteristics of the nucleus pulposus. Expression of hypoxia inducing factor-1, glucose transporter-1 and MMP-2. Cell Tissue Res. 308, 401-407
-
(2002)
Cell Tissue Res.
, vol.308
, pp. 401-407
-
-
Rajpurohit, R.1
Risbud, M.V.2
Ducheyne, P.3
Vresilovic, E.J.4
Shapiro, I.M.5
-
5
-
-
33646010313
-
Nucleus pulposus cells express HIF-1α under normoxic culture conditions. A metabolic adaptation to the intervertebral disc microenvironment
-
Risbud, M. V., Guttapalli, A., Stokes, D. G., Hawkins, D., Danielson, K. G., Schaer, T. P., Albert, T. J., and Shapiro, I. M. (2006) Nucleus pulposus cells express HIF-1α under normoxic culture conditions. A metabolic adaptation to the intervertebral disc microenvironment. J. Cell Biochem. 98, 152-159
-
(2006)
J. Cell Biochem.
, vol.98
, pp. 152-159
-
-
Risbud, M.V.1
Guttapalli, A.2
Stokes, D.G.3
Hawkins, D.4
Danielson, K.G.5
Schaer, T.P.6
Albert, T.J.7
Shapiro, I.M.8
-
6
-
-
38749107818
-
HIF-1α is a regulator of Galectin-3 expression in the intervertebral disc
-
Zeng, Y., Danielson, K. G., Albert, T. J., Shapiro, I. M., and Risbud, M. V. (2007) HIF-1α is a regulator of Galectin-3 expression in the intervertebral disc. J. Bone Miner. Res. 22, 1851-1861
-
(2007)
J. Bone Miner. Res.
, vol.22
, pp. 1851-1861
-
-
Zeng, Y.1
Danielson, K.G.2
Albert, T.J.3
Shapiro, I.M.4
Risbud, M.V.5
-
7
-
-
77956362994
-
Hypoxia-inducible factor regulation of ANK expression in nucleus pulposus cells. Possible implications in controlling dystrophic mineralization in the intervertebral disc
-
Skubutyte, R., Markova, D., Freeman, T. A., Anderson, D. G., Dion, A. S., Williams, C. J., Shapiro, I. M., and Risbud, M. V. (2010) Hypoxia-inducible factor regulation of ANK expression in nucleus pulposus cells. Possible implications in controlling dystrophic mineralization in the intervertebral disc. Arthritis Rheum. 62, 2707-2715
-
(2010)
Arthritis Rheum.
, vol.62
, pp. 2707-2715
-
-
Skubutyte, R.1
Markova, D.2
Freeman, T.A.3
Anderson, D.G.4
Dion, A.S.5
Williams, C.J.6
Shapiro, I.M.7
Risbud, M.V.8
-
8
-
-
34547763695
-
Normoxic stabilization of HIF-1α drives glycolytic metabolism and regulates aggrecan gene expression in nucleus pulposus cells of the rat intervertebral disk
-
Agrawal, A., Guttapalli, A., Narayan, S., Albert, T. J., Shapiro, I. M., and Risbud, M. V. (2007) Normoxic stabilization of HIF-1α drives glycolytic metabolism and regulates aggrecan gene expression in nucleus pulposus cells of the rat intervertebral disk. Am. J. Physiol. Cell Physiol. 293, C621-C631
-
(2007)
Am. J. Physiol. Cell Physiol.
, vol.293
-
-
Agrawal, A.1
Guttapalli, A.2
Narayan, S.3
Albert, T.J.4
Shapiro, I.M.5
Risbud, M.V.6
-
9
-
-
79959843998
-
Hypoxic regulation of β-1, 3-glucuronyltransferase 1 expression in nucleus pulposus cells of the rat intervertebral disc
-
Gogate, S. S., Nasser, R., Shapiro, I. M., and Risbud, M. V. (2011) Hypoxic regulation of β-1, 3-glucuronyltransferase 1 expression in nucleus pulposus cells of the rat intervertebral disc. Role of hypoxia-inducible factor proteins. Arthritis Rheum. 63, 1950-1960
-
(2011)
Role of Hypoxia-inducible Factor Proteins. Arthritis Rheum.
, vol.63
, pp. 1950-1960
-
-
Gogate, S.S.1
Nasser, R.2
Shapiro, I.M.3
Risbud, M.V.4
-
10
-
-
84856160786
-
HIF-1α and HIF-2α degradation is differentially regulated in nucleus pulposus cells of the intervertebral disc
-
Fujita, N., Chiba, K., Shapiro, I. M., and Risbud, M. V. (2012) HIF-1α and HIF-2α degradation is differentially regulated in nucleus pulposus cells of the intervertebral disc. J. Bone Miner. Res. 27, 401-412
-
(2012)
J. Bone Miner. Res.
, vol.27
, pp. 401-412
-
-
Fujita, N.1
Chiba, K.2
Shapiro, I.M.3
Risbud, M.V.4
-
11
-
-
84859926202
-
Tonicity enhancer binding protein (TonEBP) and hypoxia-inducible factor (HIF) coordinate heat shock protein 70 (Hsp70) expression in hypoxic nucleus pulposus cells. Role of Hsp70 in HIF-1α degradation
-
Gogate, S. S., Fujita, N., Skubutyte, R., Shapiro, I. M., and Risbud, M. V. (2012) Tonicity enhancer binding protein (TonEBP) and hypoxia-inducible factor (HIF) coordinate heat shock protein 70 (Hsp70) expression in hypoxic nucleus pulposus cells. Role of Hsp70 in HIF-1α degradation. J. Bone Miner. Res. 27, 1106-1117
-
(2012)
J. Bone Miner. Res.
, vol.27
, pp. 1106-1117
-
-
Gogate, S.S.1
Fujita, N.2
Skubutyte, R.3
Shapiro, I.M.4
Risbud, M.V.5
-
12
-
-
22544464403
-
Coordinate regulation of the oxygen-dependent degradation domains of hypoxia-inducible factor 1α
-
Chan, D. A., Sutphin, P. D., Yen, S. E., and Giaccia, A. J. (2005) Coordinate regulation of the oxygen-dependent degradation domains of hypoxia-inducible factor 1α. Mol. Cell Biol. 25, 6415-6426
-
(2005)
Mol. Cell Biol.
, vol.25
, pp. 6415-6426
-
-
Chan, D.A.1
Sutphin, P.D.2
Yen, S.E.3
Giaccia, A.J.4
-
13
-
-
0041465022
-
HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1α in normoxia
-
Berra, E., Benizri, E., Ginouvès, A., Volmat, V., Roux, D., and Pouysségur, J. (2003) HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1α in normoxia. EMBO J. 22, 4082-4090
-
(2003)
EMBO J.
, vol.22
, pp. 4082-4090
-
-
Berra, E.1
Benizri, E.2
Ginouvès, A.3
Volmat, V.4
Roux, D.5
Pouysségur, J.6
-
15
-
-
84860864145
-
Expression of prolyl hydroxylases (PHDs) is selectively controlled by HIF-1 and HIF-2 proteins in nucleus pulposus cells of the intervertebral disc
-
Fujita, N., Markova, D., Anderson, D. G., Chiba, K., Toyama Y., Shapiro I. M., and Risbud M. V. (2012) Expression of prolyl hydroxylases (PHDs) is selectively controlled by HIF-1 and HIF-2 proteins in nucleus pulposus cells of the intervertebral disc. J. Biol. Chem. 287, 16975-16986
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 16975-16986
-
-
Fujita, N.1
Markova, D.2
Anderson, D.G.3
Chiba, K.4
Toyama, Y.5
Shapiro, I.M.6
Risbud, M.V.7
-
16
-
-
27844514169
-
Two transactivation mechanisms cooperate for the bulk of HIF-1-responsive gene expression
-
Kasper, L. H., Boussouar, F., Boyd, K., Xu, W., Biesen, M., Rehg, J., Baudino, T. A., Cleveland, J. L., and Brindle, P. K. (2005) Two transactivation mechanisms cooperate for the bulk of HIF-1-responsive gene expression. EMBO J. 24, 3846-3858
-
(2005)
EMBO J.
, vol.24
, pp. 3846-3858
-
-
Kasper, L.H.1
Boussouar, F.2
Boyd, K.3
Xu, W.4
Biesen, M.5
Rehg, J.6
Baudino, T.A.7
Cleveland, J.L.8
Brindle, P.K.9
-
17
-
-
0029803552
-
An essential role for p300/CBP in the cellular response to hypoxia
-
Arany, Z., Huang, L. E., Eckner, R., Bhattacharya, S., Jiang, C., Goldberg, M. A., Bunn, H. F., and Livingston, D. M. (1996) An essential role for p300/CBP in the cellular response to hypoxia. Proc. Natl. Acad. Sci. U. S. A. 93, 12969-12973
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 12969-12973
-
-
Arany, Z.1
Huang, L.E.2
Eckner, R.3
Bhattacharya, S.4
Jiang, C.5
Goldberg, M.A.6
Bunn, H.F.7
Livingston, D.M.8
-
18
-
-
0037097861
-
FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor
-
Lando, D., Peet, D. J., Gorman, J. J., Whelan, D. A., Whitelaw, M. L., and Bruick, R. K. (2002) FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor. Genes Dev. 16, 1466-1471
-
(2002)
Genes Dev.
, vol.16
, pp. 1466-1471
-
-
Lando, D.1
Peet, D.J.2
Gorman, J.J.3
Whelan, D.A.4
Whitelaw, M.L.5
Bruick, R.K.6
-
19
-
-
0037180452
-
Structure of factor-inhibiting hypoxia-inducible factor 1: An asparaginyl hydroxylase involved in the hypoxic response pathway
-
Dann, C. E., 3rd, Bruick, R. K., and Deisenhofer, J. (2002) Structure of factor-inhibiting hypoxia-inducible factor 1: an asparaginyl hydroxylase involved in the hypoxic response pathway. Proc. Natl. Acad. Sci. U. S. A. 99, 15351-15356
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 15351-15356
-
-
Dann III, C.E.1
Bruick, R.K.2
Deisenhofer, J.3
-
20
-
-
79953891392
-
Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors
-
Tian, Y. M., Yeoh, K. K., Lee, M. K., Eriksson, T., Kessler, B. M., Kramer, H. B., Edelmann, M. J., Willam, C., Pugh, C. W., Schofield, C. J., and Ratcliffe, P. J. (2011) Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors. J. Biol. Chem. 286, 13041-13051
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 13041-13051
-
-
Tian, Y.M.1
Yeoh, K.K.2
Lee, M.K.3
Eriksson, T.4
Kessler, B.M.5
Kramer, H.B.6
Edelmann, M.J.7
Willam, C.8
Pugh, C.W.9
Schofield, C.J.10
Ratcliffe, P.J.11
-
21
-
-
0033599341
-
X11L2, a new member of the X11 protein family, interacts with Alzheimer's β-amyloid precursor protein
-
Tanahashi, H., and Tabira, T. (1999) X11L2, a new member of the X11 protein family, interacts with Alzheimer's β-amyloid precursor protein. Biochem. Biophys. Res. Commun. 255, 663-667
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.255
, pp. 663-667
-
-
Tanahashi, H.1
Tabira, T.2
-
22
-
-
0031736233
-
Mint 3: A ubiquitous mint isoform that does not bind to munc18-1 or -2
-
Okamoto, M., and Südhof, T. C. (1998) Mint 3: a ubiquitous mint isoform that does not bind to munc18-1 or -2. Eur. J. Cell Biol. 77, 161-165
-
(1998)
Eur. J. Cell Biol.
, vol.77
, pp. 161-165
-
-
Okamoto, M.1
Südhof, T.C.2
-
23
-
-
71049186343
-
Mint3 enhances the activity of hypoxiainducible factor-1 (HIF-1) in macrophages by suppressing the activity of factor inhibiting HIF-1
-
Sakamoto, T., and Seiki, M. (2009) Mint3 enhances the activity of hypoxiainducible factor-1 (HIF-1) in macrophages by suppressing the activity of factor inhibiting HIF-1. J. Biol. Chem. 284, 30350-30359
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 30350-30359
-
-
Sakamoto, T.1
Seiki, M.2
-
24
-
-
0028172988
-
Interleukin-1 β-modulated gene expression in immortalized human chondrocytes
-
Goldring, M. B., Birkhead, J. R., Suen, L. F., Yamin, R., Mizuno, S., Glowacki, J., Arbiser, J. L., and Apperley, J. F. (1994) Interleukin-1 β-modulated gene expression in immortalized human chondrocytes. J. Clin. Invest. 94, 2307-2316
-
(1994)
J. Clin. Invest.
, vol.94
, pp. 2307-2316
-
-
Goldring, M.B.1
Birkhead, J.R.2
Suen, L.F.3
Yamin, R.4
Mizuno, S.5
Glowacki, J.6
Arbiser, J.L.7
Apperley, J.F.8
-
25
-
-
84885106363
-
Recruitment of the Mint3 adaptor is necessary for export of the amyloid precursor protein (APP) from the Golgi complex
-
Caster, A. H., and Kahn, R. A. (2013) Recruitment of the Mint3 adaptor is necessary for export of the amyloid precursor protein (APP) from the Golgi complex. J. Biol. Chem. 288, 28567-28580
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 28567-28580
-
-
Caster, A.H.1
Kahn, R.A.2
-
26
-
-
84861494579
-
Subcellular FIH-1 expression patterns in invasive breast cancer in relation to HIF-1α expression
-
Hyseni, A., van der Groep, P., van der Wall, E., and van Diest, P. J. (2011) Subcellular FIH-1 expression patterns in invasive breast cancer in relation to HIF-1α expression. Cell Oncol. (Dordr.) 34, 565-570
-
(2011)
Cell Oncol. (Dordr.)
, vol.34
, pp. 565-570
-
-
Hyseni, A.1
Van Der Groep, P.2
Van Der Wall, E.3
Van Diest, P.J.4
-
27
-
-
58149189405
-
Overexpression of the oxygen sensors PHD-1, PHD-2, PHD-3, and FIH is associated with tumor aggressiveness in pancreatic endocrine tumors
-
Couvelard, A., Deschamps, L., Rebours, V., Sauvanet, A., Gatter, K., Pezzella, F., Ruszniewski, P., and Bedossa, P. (2008) Overexpression of the oxygen sensors PHD-1, PHD-2, PHD-3, and FIH Is associated with tumor aggressiveness in pancreatic endocrine tumors. Clin. Cancer Res. 14, 6634-6639
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 6634-6639
-
-
Couvelard, A.1
Deschamps, L.2
Rebours, V.3
Sauvanet, A.4
Gatter, K.5
Pezzella, F.6
Ruszniewski, P.7
Bedossa, P.8
-
28
-
-
78649630859
-
Expression of nuclear FIH independently predicts overall survival of clear cell renal cell carcinoma patients
-
Kroeze, S. G., Vermaat, J. S., van Brussel, A., van Melick, H. H., Voest, E. E., Jonges, T. G., van Diest, P. J., Hinrichs, J., Bosch, J. L., and Jans, J. J. (2010) Expression of nuclear FIH independently predicts overall survival of clear cell renal cell carcinoma patients. Eur. J. Cancer 46, 3375-3382
-
(2010)
Eur. J. Cancer
, vol.46
, pp. 3375-3382
-
-
Kroeze, S.G.1
Vermaat, J.S.2
Van Brussel, A.3
Van Melick, H.H.4
Voest, E.E.5
Jonges, T.G.6
Van Diest, P.J.7
Hinrichs, J.8
Bosch, J.L.9
Jans, J.J.10
-
29
-
-
0037386143
-
Intracellular localisation of human HIF-1α hydroxylases: Implications for oxygen sensing
-
Metzen, E., Berchner-Pfannschmidt, U., Stengel, P., Marxsen, J. H., Stolze, I., Klinger, M., Huang, W. Q., Wotzlaw, C., Hellwig-Bürgel, T., Jelkmann, W., Acker, H., and Fandrey, J. (2003) Intracellular localisation of human HIF-1α hydroxylases: implications for oxygen sensing. J. Cell Sci. 116, 1319-1326
-
(2003)
J. Cell Sci.
, vol.116
, pp. 1319-1326
-
-
Metzen, E.1
Berchner-Pfannschmidt, U.2
Stengel, P.3
Marxsen, J.H.4
Stolze, I.5
Klinger, M.6
Huang, W.Q.7
Wotzlaw, C.8
Hellwig-Bürgel, T.9
Jelkmann, W.10
Acker, H.11
Fandrey, J.12
-
30
-
-
33745394425
-
Protein kinase Cζ attenuates hypoxia-induced proliferation of fibroblasts by regulating MAP kinase phosphatase-1 expression
-
Short, M. D., Fox, S. M., Lam, C. F., Stenmark, K. R., and Das, M. (2006) Protein kinase Cζ attenuates hypoxia-induced proliferation of fibroblasts by regulating MAP kinase phosphatase-1 expression. Mol. Biol. Cell. 17, 1995-2008
-
(2006)
Mol. Biol. Cell.
, vol.17
, pp. 1995-2008
-
-
Short, M.D.1
Fox, S.M.2
Lam, C.F.3
Stenmark, K.R.4
Das, M.5
-
31
-
-
35148860529
-
Protein kinase C-mediated modulation of FIH-1 expression by the homeodomain protein CDP/Cut/Cux
-
Li, J., Wang, E., Dutta, S., Lau, J. S., Jiang, S. W., Datta, K., and Mukhopadhyay, D. (2007) Protein kinase C-mediated modulation of FIH-1 expression by the homeodomain protein CDP/Cut/Cux. Mol. Cell Biol. 27, 7345-7353
-
(2007)
Mol. Cell Biol.
, vol.27
, pp. 7345-7353
-
-
Li, J.1
Wang, E.2
Dutta, S.3
Lau, J.S.4
Jiang, S.W.5
Datta, K.6
Mukhopadhyay, D.7
-
32
-
-
0043234538
-
Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor
-
Hirsilä, M., Koivunen, P., Günzler, V., Kivirikko, K. I., and Myllyharju, J. (2003) Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor. J. Biol. Chem. 278, 30772-30780
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 30772-30780
-
-
Hirsilä, M.1
Koivunen, P.2
Günzler, V.3
Kivirikko, K.I.4
Myllyharju, J.5
-
33
-
-
1642315195
-
Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases
-
Koivunen, P., Hirsilä, M., Günzler, V., Kivirikko, K. I., and Myllyharju, J. (2004) Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases. J. Biol. Chem. 279, 9899-9904
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 9899-9904
-
-
Koivunen, P.1
Hirsilä, M.2
Günzler, V.3
Kivirikko, K.I.4
Myllyharju, J.5
-
34
-
-
84899874531
-
The role of factor inhibiting HIF (FIH-1) in inhibiting HIF-1 transcriptional activity in glioblastoma multiforme
-
Wang, E., Zhang, C., Polavaram, N., Liu, F., Wu, G., Schroeder, M. A., Lau, J. S., Mukhopadhyay, D., Jiang, S. W., O'Neill, B. P., Datta, K., and Li, J. (2014) The role of factor inhibiting HIF (FIH-1) in inhibiting HIF-1 transcriptional activity in glioblastoma multiforme. PLoS One. 9, e86102
-
(2014)
PLoS One.
, vol.9
-
-
Wang, E.1
Zhang, C.2
Polavaram, N.3
Liu, F.4
Wu, G.5
Schroeder, M.A.6
Lau, J.S.7
Mukhopadhyay, D.8
Jiang, S.W.9
O'Neill, B.P.10
Datta, K.11
Li, J.12
-
35
-
-
77958089464
-
Factor inhibiting HIF limits the expression of hypoxia-inducible genes in podocytes and distal tubular cells
-
Schödel, J., Bohr, D., Klanke, B., Schley, G., Schlötzer- Schrehardt, U., Warnecke, C., Kurtz, A., Amann, K., Eckardt, K. U., and Willam, C. (2010) Factor inhibiting HIF limits the expression of hypoxia-inducible genes in podocytes and distal tubular cells. Kidney Int. 78, 857-867
-
(2010)
Kidney Int.
, vol.78
, pp. 857-867
-
-
Schödel, J.1
Bohr, D.2
Klanke, B.3
Schley, G.4
Schlötzer-Schrehardt, U.5
Warnecke, C.6
Kurtz, A.7
Amann, K.8
Eckardt, K.U.9
Willam, C.10
-
36
-
-
84864841589
-
Hypoxia decreases podocyte expression of slit diaphragm proteins
-
Lu, H., Kapur, G., Mattoo, T. K., and Lyman, W. D. (2012) Hypoxia decreases podocyte expression of slit diaphragm proteins. Int. J. Nephrol. Renovasc. Dis. 5, 101-107
-
(2012)
Int. J. Nephrol. Renovasc. Dis.
, vol.5
, pp. 101-107
-
-
Lu, H.1
Kapur, G.2
Mattoo, T.K.3
Lyman, W.D.4
-
37
-
-
40449110083
-
HIF activation protects from acute kidney injury
-
Weidemann, A., Bernhardt, W. M., Klanke, B., Daniel, C., Buchholz, B., Câmpean, V., Amann, K., Warnecke, C., Wiesener, M. S., Eckardt, K. U., and Willam, C. (2008) HIF activation protects from acute kidney injury. J. Am. Soc. Nephrol. 19, 486-494
-
(2008)
J. Am. Soc. Nephrol.
, vol.19
, pp. 486-494
-
-
Weidemann, A.1
Bernhardt, W.M.2
Klanke, B.3
Daniel, C.4
Buchholz, B.5
Câmpean, V.6
Amann, K.7
Warnecke, C.8
Wiesener, M.S.9
Eckardt, K.U.10
Willam, C.11
-
38
-
-
78649962039
-
Renal protection in chronic kidney disease: Hypoxia-inducible factor activation vs angiotensin II blockade
-
Deng, A., Arndt, M. A., Satriano, J., Singh, P., Rieg, T., Thomson, S., Tang, T., and Blantz, R. C. (2010) Renal protection in chronic kidney disease: hypoxia-inducible factor activation vs. angiotensin II blockade. Am. J. Physiol. Renal Physiol. 299, F1365-F1373
-
(2010)
Am. J. Physiol. Renal Physiol.
, vol.299
-
-
Deng, A.1
Arndt, M.A.2
Satriano, J.3
Singh, P.4
Rieg, T.5
Thomson, S.6
Tang, T.7
Blantz, R.C.8
-
39
-
-
77955284188
-
The asparaginyl hydroxylase factor inhibiting HIF-1α is an essential regulator of metabolism
-
Zhang, N., Fu, Z., Linke, S., Chicher, J., Gorman, J. J., Visk, D., Haddad, G. G., Poellinger, L., Peet, D. J., Powell, F., and Johnson, R. S. (2010) The asparaginyl hydroxylase factor inhibiting HIF-1α is an essential regulator of metabolism. Cell Metab. 11, 364-378
-
(2010)
Cell Metab.
, vol.11
, pp. 364-378
-
-
Zhang, N.1
Fu, Z.2
Linke, S.3
Chicher, J.4
Gorman, J.J.5
Visk, D.6
Haddad, G.G.7
Poellinger, L.8
Peet, D.J.9
Powell, F.10
Johnson, R.S.11
-
40
-
-
33749518516
-
Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)
-
Cockman, M. E., Lancaster, D. E., Stolze, I. P., Hewitson, K. S., McDonough, M. A., Coleman, M. L., Coles, C. H., Yu, X., Hay, R. T., Ley, S. C., Pugh, C. W., Oldham, N. J., Masson, N., Schofield, C. J., and Ratcliffe, P. J. (2006) Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH). Proc. Natl. Acad. Sci. U. S. A. 103, 14767-14772
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 14767-14772
-
-
Cockman, M.E.1
Lancaster, D.E.2
Stolze, I.P.3
Hewitson, K.S.4
McDonough, M.A.5
Coleman, M.L.6
Coles, C.H.7
Yu, X.8
Hay, R.T.9
Ley, S.C.10
Pugh, C.W.11
Oldham, N.J.12
Masson, N.13
Schofield, C.J.14
Ratcliffe, P.J.15
-
41
-
-
34548239264
-
Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor
-
Coleman, M. L., McDonough, M. A., Hewitson, K. S., Coles, C., Mecinovic, J., Edelmann, M., Cook, K. M., Cockman, M. E., Lancaster, D. E., Kessler, B. M., Oldham, N. J., Ratcliffe, P. J., and Schofield, C. J. (2007) Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor. J. Biol. Chem. 282, 24027-24038
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 24027-24038
-
-
Coleman, M.L.1
McDonough, M.A.2
Hewitson, K.S.3
Coles, C.4
Mecinovic, J.5
Edelmann, M.6
Cook, K.M.7
Cockman, M.E.8
Lancaster, D.E.9
Kessler, B.M.10
Oldham, N.J.11
Ratcliffe, P.J.12
Schofield, C.J.13
-
42
-
-
63049095888
-
Differences in hydroxylation and binding of Notch and HIF-1α demonstrate substrate selectivity for factor inhibiting HIF-1 (FIH-1)
-
Wilkins, S. E., Hyvärinen, J., Chicher, J., Gorman, J. J., Peet, D. J., Bilton, R. L., and Koivunen, P. (2009) Differences in hydroxylation and binding of Notch and HIF-1α demonstrate substrate selectivity for factor inhibiting HIF-1 (FIH-1). Int. J. Biochem. Cell Biol. 41, 1563-1571
-
(2009)
Int. J. Biochem. Cell Biol.
, vol.41
, pp. 1563-1571
-
-
Wilkins, S.E.1
Hyvärinen, J.2
Chicher, J.3
Gorman, J.J.4
Peet, D.J.5
Bilton, R.L.6
Koivunen, P.7
-
43
-
-
80053211441
-
Quantitative mass spectrometry reveals dynamics of factor-inhibiting hypoxia-inducible factor-catalyzed hydroxylation
-
Singleton, R. S., Trudgian, D. C., Fischer, R., Kessler, B. M., Ratcliffe, P. J., and Cockman, M. E. (2011) Quantitative mass spectrometry reveals dynamics of factor-inhibiting hypoxia-inducible factor-catalyzed hydroxylation. J. Biol. Chem. 286, 33784-33794
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 33784-33794
-
-
Singleton, R.S.1
Trudgian, D.C.2
Fischer, R.3
Kessler, B.M.4
Ratcliffe, P.J.5
Cockman, M.E.6
-
44
-
-
79955567515
-
Hypoxia activates the notch signaling pathway in cells of the intervertebral disc: Implications in degenerative disc disease
-
Hiyama, A., Skubutyte, R., Markova, D., Anderson, D. G., Yadla, S., Sakai, D., Mochida, J., Albert, T. J., Shapiro, I. M., and Risbud, M. V. (2011) Hypoxia activates the notch signaling pathway in cells of the intervertebral disc: implications in degenerative disc disease. Arthritis Rheum. 63, 1355-1364
-
(2011)
Arthritis Rheum.
, vol.63
, pp. 1355-1364
-
-
Hiyama, A.1
Skubutyte, R.2
Markova, D.3
Anderson, D.G.4
Yadla, S.5
Sakai, D.6
Mochida, J.7
Albert, T.J.8
Shapiro, I.M.9
Risbud, M.V.10
-
45
-
-
78651325895
-
Prevention of apoptosis by the interaction between FIH1 and Bax
-
Yan, B., Kong, M., and Chen, Y. H. (2011) Prevention of apoptosis by the interaction between FIH1 and Bax. Mol. Cell Biochem. 348, 1-9
-
(2011)
Mol. Cell Biochem.
, vol.348
, pp. 1-9
-
-
Yan, B.1
Kong, M.2
Chen, Y.H.3
-
46
-
-
84869203441
-
Prolyl hydroxylase 3 (PHD3) modulates catabolic effects of tumor necrosis factor-α (TNF-α) on cells of the nucleus pulposus through co-activation of nuclear factor κB (NF-κB)/p65 signaling
-
Fujita, N., Gogate, S. S., Chiba, K., Toyama, Y., Shapiro, I. M., and Risbud, M. V. (2012) Prolyl hydroxylase 3 (PHD3) modulates catabolic effects of tumor necrosis factor-α (TNF-α) on cells of the nucleus pulposus through co-activation of nuclear factor κB (NF-κB)/p65 signaling. J. Biol. Chem. 287, 39942-39953
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 39942-39953
-
-
Fujita, N.1
Gogate, S.S.2
Chiba, K.3
Toyama, Y.4
Shapiro, I.M.5
Risbud, M.V.6
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