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Volumn 289, Issue 30, 2014, Pages 20448-20461

Synergistic signaling of tumor cell invasiveness by Hepatocyte growth factor and hypoxia

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; CELLS; CHEMICAL ACTIVATION; CYTOLOGY; OXYGEN; PROTEINS; SIGNALING;

EID: 84905392051     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.580597     Document Type: Article
Times cited : (25)

References (50)
  • 3
    • 33749238874 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumor suppressor gene product represses oncogenic betacatenin signaling in renal carcinoma cells
    • Peruzzi, B., Athauda, G., and Bottaro, D. P. (2006) The von Hippel-Lindau tumor suppressor gene product represses oncogenic betacatenin signaling in renal carcinoma cells. Proc. Natl. Acad. Sci. U. S. A. 103, 14531-14536
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 14531-14536
    • Peruzzi, B.1    Athauda, G.2    Bottaro, D.P.3
  • 4
    • 84905400449 scopus 로고    scopus 로고
    • HGF basis sequence: Mouse
    • 10.6072/H0. MP. A004032.01
    • Rubin, J. S., and Bottaro, D. P. (2011) HGF basis sequence: mouse. UCSD Molecule Pages 10.6072/H0. MP. A004032.01
    • (2011) UCSD Molecule Pages
    • Rubin, J.S.1    Bottaro, D.P.2
  • 8
    • 84887019324 scopus 로고    scopus 로고
    • Hypoxia and metastasis in an orthotopic cervix cancer xenograft model
    • Chaudary, N., Mujcic, H., Wouters, B. G., and Hill, R. P. (2013) Hypoxia and metastasis in an orthotopic cervix cancer xenograft model. Radiother. Oncol. 108, 506-510
    • (2013) Radiother. Oncol. , vol.108 , pp. 506-510
    • Chaudary, N.1    Mujcic, H.2    Wouters, B.G.3    Hill, R.P.4
  • 10
    • 33745354482 scopus 로고    scopus 로고
    • Hypoxia enhances c-Met/HGF receptor expression and signaling by activating HIF-1γ in human salivary gland cancer cells
    • Hara, S., Nakashiro, K., Klosek, S. K., Ishikawa, T., Shintani, S., and Hamakawa, H. (2006) Hypoxia enhances c-Met/HGF receptor expression and signaling by activating HIF-1γ in human salivary gland cancer cells. Oral Oncol. 42, 593-598
    • (2006) Oral Oncol. , vol.42 , pp. 593-598
    • Hara, S.1    Nakashiro, K.2    Klosek, S.K.3    Ishikawa, T.4    Shintani, S.5    Hamakawa, H.6
  • 11
    • 33751569391 scopus 로고    scopus 로고
    • Tumor-stromal cell interaction under hypoxia increases the invasiveness of pancreatic cancer cells through the hepatocyte growth factor/c-Met pathway
    • Ide, T., Kitajima, Y., Miyoshi, A., Ohtsuka, T., Mitsuno, M., Ohtaka, K., Koga, Y., and Miyazaki, K. (2006) Tumor-stromal cell interaction under hypoxia increases the invasiveness of pancreatic cancer cells through the hepatocyte growth factor/c-Met pathway. Int. J. Cancer 119, 2750-2759
    • (2006) Int. J. Cancer , vol.119 , pp. 2750-2759
    • Ide, T.1    Kitajima, Y.2    Miyoshi, A.3    Ohtsuka, T.4    Mitsuno, M.5    Ohtaka, K.6    Koga, Y.7    Miyazaki, K.8
  • 15
    • 0035805597 scopus 로고    scopus 로고
    • Activation of hepatocyte growth factor (HGF) by endogenous HGF activator is required for metanephric kidney morphogenesis in vitro
    • van Adelsberg, J., Sehgal, S., Kukes, A., Brady, C., Barasch, J., Yang, J., and Huan, Y. (2001) Activation of hepatocyte growth factor (HGF) by endogenous HGF activator is required for metanephric kidney morphogenesis in vitro. J. Biol. Chem. 276, 15099-15106
    • (2001) J. Biol. Chem. , vol.276 , pp. 15099-15106
    • Van Adelsberg, J.1    Sehgal, S.2    Kukes, A.3    Brady, C.4    Barasch, J.5    Yang, J.6    Huan, Y.7
  • 16
    • 33745697763 scopus 로고    scopus 로고
    • Targeting the c-Met signaling pathway in cancer
    • Peruzzi, B., and Bottaro, D. P. (2006) Targeting the c-Met signaling pathway in cancer. Clin. Cancer Res. 12, 3657-3660
    • (2006) Clin. Cancer Res. , vol.12 , pp. 3657-3660
    • Peruzzi, B.1    Bottaro, D.P.2
  • 17
    • 33845673263 scopus 로고    scopus 로고
    • β-Catenin signaling: Linking renal cell carcinoma and polycystic kidney disease
    • Peruzzi, B., and Bottaro, D. P. (2006) β-Catenin signaling: linking renal cell carcinoma and polycystic kidney disease. Cell Cycle 5, 2839-2841
    • (2006) Cell Cycle , vol.5 , pp. 2839-2841
    • Peruzzi, B.1    Bottaro, D.P.2
  • 19
    • 80052214870 scopus 로고    scopus 로고
    • Gq protein-induced apoptosis is mediated by AKT kinase inhibition that leads to protein kinase C-induced c-Jun. N-terminal kinase activation
    • Ben-Ami, I., Yao, Z., Naor, Z., and Seger, R. (2011) Gq protein-induced apoptosis is mediated by AKT kinase inhibition that leads to protein kinase C-induced c-Jun. N-terminal kinase activation. J. Biol. Chem. 286, 31022-31031
    • (2011) J. Biol. Chem. , vol.286 , pp. 31022-31031
    • Ben-Ami, I.1    Yao, Z.2    Naor, Z.3    Seger, R.4
  • 20
    • 34250635347 scopus 로고    scopus 로고
    • Protein kinase C-mediated downregulation of cyclin D1 involves activation of the translational repressor 4E-BP1 via a phosphoinositide 3-kinase/Akt-independent, protein phosphatase 2A-dependent mechanism in intestinal epithelial cells
    • Guan, L., Song, K., Pysz, M. A., Curry, K. J., Hizli, A. A., Danielpour, D., Black, A. R., and Black, J. D. (2007) Protein kinase C-mediated downregulation of cyclin D1 involves activation of the translational repressor 4E-BP1 via a phosphoinositide 3-kinase/Akt-independent, protein phosphatase 2A-dependent mechanism in intestinal epithelial cells. J. Biol. Chem. 282, 14213-14225
    • (2007) J. Biol. Chem. , vol.282 , pp. 14213-14225
    • Guan, L.1    Song, K.2    Pysz, M.A.3    Curry, K.J.4    Hizli, A.A.5    Danielpour, D.6    Black, A.R.7    Black, J.D.8
  • 21
    • 77953408308 scopus 로고    scopus 로고
    • Physiological regulation of Akt activity and stability
    • Liao, Y., and Hung, M. C. (2010) Physiological regulation of Akt activity and stability. Am. J. Transl. Res. 2, 19-42
    • (2010) Am. J. Transl. Res. , vol.2 , pp. 19-42
    • Liao, Y.1    Hung, M.C.2
  • 22
    • 0032961449 scopus 로고    scopus 로고
    • Differential distribution of protein phosphatase 2A in human breast carcinoma cell lines and its relation to estrogen receptor status
    • Gopalakrishna, R., Gundimeda, U., Fontana, J. A., and Clarke, R. (1999) Differential distribution of protein phosphatase 2A in human breast carcinoma cell lines and its relation to estrogen receptor status. Cancer Lett. 136, 143-151
    • (1999) Cancer Lett. , vol.136 , pp. 143-151
    • Gopalakrishna, R.1    Gundimeda, U.2    Fontana, J.A.3    Clarke, R.4
  • 25
    • 34548188741 scopus 로고    scopus 로고
    • Self-eating and self-killing: Cross-talk between autophagy and apoptosis
    • Maiuri, M. C., Zalckvar, E., Kimchi, A., and Kroemer, G. (2007) Self-eating and self-killing: cross-talk between autophagy and apoptosis. Nat. Rev. Mol. Cell Biol. 8, 741-752
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 741-752
    • Maiuri, M.C.1    Zalckvar, E.2    Kimchi, A.3    Kroemer, G.4
  • 26
    • 35448981935 scopus 로고    scopus 로고
    • Autophagy: From phenomenology to molecular understanding in less than a decade
    • Klionsky, D. J. (2007) Autophagy: from phenomenology to molecular understanding in less than a decade. Nat. Rev. Mol. Cell Biol. 8, 931-937
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 931-937
    • Klionsky, D.J.1
  • 29
    • 33645090169 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1-dependent repression of E-cadherin in von Hippel-Lindau tumor suppressornull renal cell carcinoma mediated by TCF3, ZFHX1A, and ZFHX1B
    • Krishnamachary, B., Zagzag, D., Nagasawa, H., Rainey, K., Okuyama, H., Baek, J. H., and Semenza, G. L. (2006) Hypoxia-inducible factor-1-dependent repression of E-cadherin in von Hippel-Lindau tumor suppressornull renal cell carcinoma mediated by TCF3, ZFHX1A, and ZFHX1B. Cancer Res. 66, 2725-2731
    • (2006) Cancer Res. , vol.66 , pp. 2725-2731
    • Krishnamachary, B.1    Zagzag, D.2    Nagasawa, H.3    Rainey, K.4    Okuyama, H.5    Baek, J.H.6    Semenza, G.L.7
  • 31
    • 34547124062 scopus 로고    scopus 로고
    • Hypoxia: A key regulator of angiogenesis in cancer
    • Liao, D., and Johnson, R. S. (2007) Hypoxia: a key regulator of angiogenesis in cancer. Cancer Metastasis Rev. 26, 281-290
    • (2007) Cancer Metastasis Rev. , vol.26 , pp. 281-290
    • Liao, D.1    Johnson, R.S.2
  • 32
    • 77950476293 scopus 로고    scopus 로고
    • ERβ impedes prostate cancer EMT by destabilizing HIF-1γ and inhibiting VEGF-mediated snail nuclear localization: Implications for Gleason grading
    • Mak, P., Leav, I., Pursell, B., Bae, D., Yang, X., Taglienti, C. A., Gouvin, L. M., Sharma, V. M., and Mercurio, A. M. (2010) ERβ impedes prostate cancer EMT by destabilizing HIF-1γ and inhibiting VEGF-mediated snail nuclear localization: implications for Gleason grading. Cancer Cell 17, 319-332
    • (2010) Cancer Cell , vol.17 , pp. 319-332
    • Mak, P.1    Leav, I.2    Pursell, B.3    Bae, D.4    Yang, X.5    Taglienti, C.A.6    Gouvin, L.M.7    Sharma, V.M.8    Mercurio, A.M.9
  • 33
    • 80052221592 scopus 로고    scopus 로고
    • Interplay between HDAC3 and WDR5 is essential for hypoxia-induced epithelial-mesenchymal transition
    • Wu, M. Z., Tsai, Y. P., Yang, M. H., Huang, C. H., Chang, S. Y., Chang, C. C., Teng, S. C., and Wu, K. J. (2011) Interplay between HDAC3 and WDR5 is essential for hypoxia-induced epithelial-mesenchymal transition. Mol. Cell 43, 811-822
    • (2011) Mol. Cell , vol.43 , pp. 811-822
    • Wu, M.Z.1    Tsai, Y.P.2    Yang, M.H.3    Huang, C.H.4    Chang, S.Y.5    Chang, C.C.6    Teng, S.C.7    Wu, K.J.8
  • 34
    • 12844251358 scopus 로고    scopus 로고
    • Identification of ASK1, MKK4, JNK, c-Jun, and caspase-3 as a signaling cascade involved in cadmium-induced neuronal cell apoptosis
    • Kim, S. D., Moon, C. K., Eun, S. Y., Ryu, P. D., and Jo, S. A. (2005) Identification of ASK1, MKK4, JNK, c-Jun, and caspase-3 as a signaling cascade involved in cadmium-induced neuronal cell apoptosis. Biochem. Biophys. Res. Commun. 328, 326-334
    • (2005) Biochem. Biophys. Res. Commun. , vol.328 , pp. 326-334
    • Kim, S.D.1    Moon, C.K.2    Eun, S.Y.3    Ryu, P.D.4    Jo, S.A.5
  • 35
    • 33750909999 scopus 로고    scopus 로고
    • Reactive oxygen species-induced activation of the MAP kinase signaling pathways
    • McCubrey, J. A., Lahair, M. M., and Franklin, R. A. (2006) Reactive oxygen species-induced activation of the MAP kinase signaling pathways. Antioxid. Redox. Signal. 8, 1775-1789
    • (2006) Antioxid. Redox. Signal. , vol.8 , pp. 1775-1789
    • McCubrey, J.A.1    Lahair, M.M.2    Franklin, R.A.3
  • 36
    • 33644958235 scopus 로고    scopus 로고
    • Critical role of ASK1 in the 6-hydroxydopamineinduced apoptosis in human neuroblastoma SH-SY5Y cells
    • Ouyang, M., and Shen, X. (2006) Critical role of ASK1 in the 6-hydroxydopamineinduced apoptosis in human neuroblastoma SH-SY5Y cells. J. Neurochem. 97, 234-244
    • (2006) J. Neurochem. , vol.97 , pp. 234-244
    • Ouyang, M.1    Shen, X.2
  • 37
    • 38349132592 scopus 로고    scopus 로고
    • Selenium attenuates ROSmediated apoptotic cell death of injured spinal cord through prevention of mitochondria dysfunction: In vitro and in vivo study
    • Yeo, J. E., Kim, J. H., and Kang, S. K. (2008) Selenium attenuates ROSmediated apoptotic cell death of injured spinal cord through prevention of mitochondria dysfunction: in vitro and in vivo study. Cell Physiol. Biochem. 21, 225-238
    • (2008) Cell Physiol. Biochem. , vol.21 , pp. 225-238
    • Yeo, J.E.1    Kim, J.H.2    Kang, S.K.3
  • 38
    • 0142043984 scopus 로고    scopus 로고
    • Redox signaling and the MAP kinase pathways
    • Torres, M., and Forman, H. J. (2003) Redox signaling and the MAP kinase pathways. Biofactors 17, 287-296
    • (2003) Biofactors , vol.17 , pp. 287-296
    • Torres, M.1    Forman, H.J.2
  • 39
    • 84880822964 scopus 로고    scopus 로고
    • Mitochondrial dysfunction promotes breast cancer cell migration and invasion through HIF1γ accumulation via increased production of reactive oxygen species
    • Ma, J., Zhang, Q., Chen, S., Fang, B., Yang, Q., Chen, C., Miele, L., Sarkar, F. H., Xia, J., and Wang, Z. (2013) Mitochondrial dysfunction promotes breast cancer cell migration and invasion through HIF1γ accumulation via increased production of reactive oxygen species. PLoS One 8, e69485
    • (2013) PLoS One , vol.8
    • Ma, J.1    Zhang, Q.2    Chen, S.3    Fang, B.4    Yang, Q.5    Chen, C.6    Miele, L.7    Sarkar, F.H.8    Xia, J.9    Wang, Z.10
  • 40
    • 27144512084 scopus 로고    scopus 로고
    • Met/hepatocyte growth factor receptor ubiquitination suppresses transformation and is required for Hrs phosphorylation
    • Abella, J. V., Peschard, P., Naujokas, M. A., Lin, T., Saucier, C., Urbé, S., and Park, M. (2005) Met/hepatocyte growth factor receptor ubiquitination suppresses transformation and is required for Hrs phosphorylation. Mol. Cell. Biol. 25, 9632-9645
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 9632-9645
    • Abella, J.V.1    Peschard, P.2    Naujokas, M.A.3    Lin, T.4    Saucier, C.5    Urbé, S.6    Park, M.7
  • 41
    • 0037148532 scopus 로고    scopus 로고
    • Ras and TGFβ cooperatively regulate epithelial cell plasticity and metastasis: Dissection of Ras signaling pathways
    • Janda, E., Lehmann, K., Killisch, I., Jechlinger, M., Herzig, M., Downward, J., Beug, H., and Grünert, S. (2002) Ras and TGFβ cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways. J. Cell Biol. 156, 299-313
    • (2002) J. Cell Biol. , vol.156 , pp. 299-313
    • Janda, E.1    Lehmann, K.2    Killisch, I.3    Jechlinger, M.4    Herzig, M.5    Downward, J.6    Beug, H.7    Grünert, S.8
  • 43
    • 0032500111 scopus 로고    scopus 로고
    • Activation of the 41/43 kDa mitogen-activated protein kinase signaling pathway is required for hepatocyte growth factor-induced cell scattering
    • Tanimura, S., Chatani, Y., Hoshino, R., Sato, M., Watanabe, S., Kataoka, T., Nakamura, T., and Kohno, M. (1998) Activation of the 41/43 kDa mitogen-activated protein kinase signaling pathway is required for hepatocyte growth factor-induced cell scattering. Oncogene 17, 57-65
    • (1998) Oncogene , vol.17 , pp. 57-65
    • Tanimura, S.1    Chatani, Y.2    Hoshino, R.3    Sato, M.4    Watanabe, S.5    Kataoka, T.6    Nakamura, T.7    Kohno, M.8
  • 44
    • 77952930298 scopus 로고    scopus 로고
    • The investigation of mitogen-activated protein kinase phosphatase-1 as a potential pharmacological target in non-small cell lung carcinomas, assisted by non-invasive molecular imaging
    • Tai, C. J., Wu, A. T., Chiou, J. F., Jan, H. J., Wei, H. J., Hsu, C. H., Lin, C. T., Chiu, W. T., Wu, C. W., Lee, H. M., and Deng, W. P. (2010) The investigation of mitogen-activated protein kinase phosphatase-1 as a potential pharmacological target in non-small cell lung carcinomas, assisted by non-invasive molecular imaging. BMC Cancer 10, 95
    • (2010) BMC Cancer , vol.10 , pp. 95
    • Tai, C.J.1    Wu, A.T.2    Chiou, J.F.3    Jan, H.J.4    Wei, H.J.5    Hsu, C.H.6    Lin, C.T.7    Chiu, W.T.8    Wu, C.W.9    Lee, H.M.10    Deng, W.P.11
  • 46
    • 33847026354 scopus 로고    scopus 로고
    • Autophagy delays apoptotic death in breast cancer cells following DNA damage
    • Abedin, M. J., Wang, D., McDonnell, M. A., Lehmann, U., and Kelekar, A. (2007) Autophagy delays apoptotic death in breast cancer cells following DNA damage. Cell Death Differ. 14, 500-510
    • (2007) Cell Death Differ. , vol.14 , pp. 500-510
    • Abedin, M.J.1    Wang, D.2    McDonnell, M.A.3    Lehmann, U.4    Kelekar, A.5
  • 49
    • 84881027754 scopus 로고    scopus 로고
    • Rapid estrogen receptor signaling mediates estrogen-induced inhibition of vascular smooth muscle cell proliferation
    • Ueda, K., Lu, Q., Baur, W., Aronovitz, M. J., and Karas, R. H. (2013) Rapid estrogen receptor signaling mediates estrogen-induced inhibition of vascular smooth muscle cell proliferation. Arterioscler. Thromb. Vasc. Biol. 33, 1837-1843
    • (2013) Arterioscler. Thromb. Vasc. Biol. , vol.33 , pp. 1837-1843
    • Ueda, K.1    Lu, Q.2    Baur, W.3    Aronovitz, M.J.4    Karas, R.H.5


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