Identification of ASK1, MKK4, JNK, c-Jun, and caspase-3 as a signaling cascade involved in cadmium-induced neuronal cell apoptosis

Biochemical and Biophysical Research Communications

Volumn 328, Issue 1, 2005, Pages 326-334

  Kim, Sun Don ^a   Moon, Chang Kyu ^b   Eun, Su Yong ^a,b   Ryu, Pan Dong ^a   Jo, Sangmee Ahn ^a,b  

^a Korea National Institute of Health   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Apoptosis; c Jun; Cadmium; Caspase 3; MAP kinases; Oxidative stress; Signaling

Indexed keywords

ACETYLCYSTEINE; APOPTOSIS SIGNAL REGULATING KINASE 1; BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CADMIUM; CASPASE 3; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; PROTEIN C JUN; SCAVENGER; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CROSS LINKING; DATA ANALYSIS; ENZYME ACTIVITY; ENZYME INHIBITION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; NERVE CELL NECROSIS; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

APOPTOSIS; CADMIUM; CASPASE 3; CASPASES; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE KINASE 4; MAP KINASE KINASE KINASE 5; MAP KINASE KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MULTIENZYME COMPLEXES; NEUROBLASTOMA; NEURONS; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

EID: 12844251358     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.11.173     Document Type: Article

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