-
1
-
-
0024444624
-
Pathology, histochem-istry and immunocytochemistry of lesions in acute multiple sclerosis
-
Adams CW, Poston RN, Buk SJ. 1989. Pathology, histochem-istry and immunocytochemistry of lesions in acute multiple sclerosis. J Neurol Sci 92:291-306.
-
(1989)
J Neurol Sci
, vol.92
, pp. 291-306
-
-
Adams, C.W.1
Poston, R.N.2
Buk, S.J.3
-
2
-
-
84879881949
-
CXCL13 is a biomarker of inflammation in multiple sclerosis, neuromyelitis optica, and other neurological conditions
-
Alvarez E, Piccio L, Mikesell RJ, Klawiter EC, Parks BJ, Naismith RT, and others. 2013. CXCL13 is a biomarker of inflammation in multiple sclerosis, neuromyelitis optica, and other neurological conditions. Mult Scler 19:1204-1208.
-
(2013)
Mult Scler
, vol.19
, pp. 1204-1208
-
-
Alvarez, E.1
Piccio, L.2
Mikesell, R.J.3
Klawiter, E.C.4
Parks, B.J.5
Naismith, R.T.6
-
3
-
-
0037376779
-
A new approach for evaluating antigen-specific T cell responses to myelin antigens during the course of multiple sclerosis
-
Arbour N, Holz A, Sipe JC, Naniche D, Romine JS, Zyroff J, and others. 2003. A new approach for evaluating antigen-specific T cell responses to myelin antigens during the course of multiple sclerosis. J Neuroimmunol 137:197-209.
-
(2003)
J Neuroimmunol
, vol.137
, pp. 197-209
-
-
Arbour, N.1
Holz, A.2
Sipe, J.C.3
Naniche, D.4
Romine, J.S.5
Zyroff, J.6
-
4
-
-
84876337179
-
Modulation of immune function occurs within hours of therapy initiation for multiple sclerosis
-
Ayers CL, Mendoza JP, Sinha S, Cunnusamy K, Greenberg BM, Frohman EM, and others. 2013. Modulation of immune function occurs within hours of therapy initiation for multiple sclerosis. Clin Immunol 147:105-119.
-
(2013)
Clin Immunol
, vol.147
, pp. 105-119
-
-
Ayers, C.L.1
Mendoza, J.P.2
Sinha, S.3
Cunnusamy, K.4
Greenberg, B.M.5
Frohman, E.M.6
-
5
-
-
0032966258
-
Interferon-gamma secretion by peripheral blood T-cell subsets in multiple sclerosis: Correlation with disease phase and interferon-beta therapy
-
Becher B, Giacomini PS, Pelletier D, McCrea E, Prat A, Antel JP. 1999. Interferon-gamma secretion by peripheral blood T-cell subsets in multiple sclerosis: correlation with disease phase and interferon-beta therapy. Ann Neurol 45: 247-250.
-
(1999)
Ann Neurol
, vol.45
, pp. 247-250
-
-
Becher, B.1
Giacomini, P.S.2
Pelletier, D.3
McCrea, E.4
Prat, A.5
Antel, J.P.6
-
6
-
-
0033786776
-
Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: Results of a phase II clinical trial with an altered peptide ligand
-
Bielekova B, Goodwin B, Richert N, Cortese I, Kondo T, Afshar G, and others. 2000. Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand. Nat Med 6:1167-1175.
-
(2000)
Nat Med
, vol.6
, pp. 1167-1175
-
-
Bielekova, B.1
Goodwin, B.2
Richert, N.3
Cortese, I.4
Kondo, T.5
Afshar, G.6
-
7
-
-
84870722172
-
Cer-ebrospinal fluid IL-12p40, CXCL13 and IL-8 as a combinatorial biomarker of active intrathecal inflammation
-
Bielekova B, Komori M, Xu Q, Reich DS, Wu T. 2012. Cer-ebrospinal fluid IL-12p40, CXCL13 and IL-8 as a combinatorial biomarker of active intrathecal inflammation. PLoS One 7:e48370.
-
(2012)
PLoS One
, vol.7
-
-
Bielekova, B.1
Komori, M.2
Xu, Q.3
Reich, D.S.4
Wu, T.5
-
8
-
-
1542723658
-
Expansion and functional relevance of high-avidity myelin-specific CD4+ T cells in multiple sclerosis
-
Bielekova B, Sung MH, Kadom N, Simon R, McFarland H, Martin R. 2004. Expansion and functional relevance of high-avidity myelin-specific CD4 + T cells in multiple sclerosis. J Immunol 172:3893-3904.
-
(2004)
J Immunol
, vol.172
, pp. 3893-3904
-
-
Bielekova, B.1
Sung, M.H.2
Kadom, N.3
Simon, R.4
McFarland, H.5
Martin, R.6
-
9
-
-
0032524181
-
ELI-spot of Th-1 cytokine secreting PBMC's in multiple sclerosis: Correlation with MRI lesions
-
Calabresi PA, Fields NS, Farnon EC, Frank JA, Bash CN, Kawanashi T, and others. 1998. ELI-spot of Th-1 cytokine secreting PBMC's in multiple sclerosis: correlation with MRI lesions. J Neuroimmunol 85:212-219.
-
(1998)
J Neuroimmunol
, vol.85
, pp. 212-219
-
-
Calabresi, P.A.1
Fields, N.S.2
Farnon, E.C.3
Frank, J.A.4
Bash, C.N.5
Kawanashi, T.6
-
10
-
-
84874566824
-
Systemic inflammation in progressive multiple sclerosis involves follicular T-helper, Th17-and activated B-cells and correlates with progression
-
Christensen JR, Börnsen L, Ratzer R, Piehl F, Khademi M, Olsson T, and others. 2013. Systemic inflammation in progressive multiple sclerosis involves follicular T-helper, Th17-and activated B-cells and correlates with progression. PLoS One 8:e57820.
-
(2013)
PLoS One
, vol.8
-
-
Christensen, J.R.1
Börnsen, L.2
Ratzer, R.3
Piehl, F.4
Khademi, M.5
Olsson, T.6
-
11
-
-
76149140914
-
Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis
-
Cohen JA, Barkhof F, Comi G, Hartung HP, Khatri BO, Montalban X, and others. 2010. Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis. N Engl J Med 362:402-415.
-
(2010)
N Engl J Med
, vol.362
, pp. 402-415
-
-
Cohen, J.A.1
Barkhof, F.2
Comi, G.3
Hartung, H.P.4
Khatri, B.O.5
Montalban, X.6
-
12
-
-
84869507357
-
Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: A randomised controlled phase 3 trial
-
Coles AJ, Twyman CL, Arnold DL, Cohen JA, Confavreux C, Fox EJ, and others. 2012. Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: a randomised controlled phase 3 trial. Lancet 380:1829-1839.
-
(2012)
Lancet
, vol.380
, pp. 1829-1839
-
-
Coles, A.J.1
Twyman, C.L.2
Arnold, D.L.3
Cohen, J.A.4
Confavreux, C.5
Fox, E.J.6
-
13
-
-
0028906889
-
Patterns of cytokine secretion by auto-reactive proteolipid protein-specific T cell clones during the course of multiple sclerosis
-
Correale J, Gilmore W, McMillan M, Li S, McCarthy K, Le T, and others. 1995. Patterns of cytokine secretion by auto-reactive proteolipid protein-specific T cell clones during the course of multiple sclerosis. J Immunol 154:2959-2968.
-
(1995)
J Immunol
, vol.154
, pp. 2959-2968
-
-
Correale, J.1
Gilmore, W.2
McMillan, M.3
Li, S.4
McCarthy, K.5
Le, T.6
-
14
-
-
84876479682
-
Diminished Th17 (not Th1) responses underlie multiple sclerosis disease abrogation after hematopoietic stem cell transplantation
-
Darlington PJ, Touil T, Doucet JS, Gaucher D, Zeidan J, Gauchat D, and others. 2013. Diminished Th17 (not Th1) responses underlie multiple sclerosis disease abrogation after hematopoietic stem cell transplantation. Ann Neurol 73:341-354.
-
(2013)
Ann Neurol
, vol.73
, pp. 341-354
-
-
Darlington, P.J.1
Touil, T.2
Doucet, J.S.3
Gaucher, D.4
Zeidan, J.5
Gauchat, D.6
-
15
-
-
84857062025
-
Lesion detection at seven Tesla in multiple sclerosis using magnetisation prepared 3D-FLAIR and 3D-DIR
-
de Graaf WL, Zwanenburg JJ, Visser F, Wattjes MP, Pouwels PJ, Geurts JJ, and others. 2012. Lesion detection at seven Tesla in multiple sclerosis using magnetisation prepared 3D-FLAIR and 3D-DIR. Eur Radiol 22:221-231.
-
(2012)
Eur Radiol
, vol.22
, pp. 221-231
-
-
De Graaf, W.L.1
Zwanenburg, J.J.2
Visser, F.3
Wattjes, M.P.4
Pouwels, P.J.5
Geurts, J.J.6
-
16
-
-
0005966256
-
T-cell responses to myelin antigens in multiple sclerosis; Relevance of the predominant autoimmune reactivity to myelin oligodendrocyte glycopro-tein
-
de Rosbo NK, Ben-Nun A. 1998. T-cell responses to myelin antigens in multiple sclerosis; relevance of the predominant autoimmune reactivity to myelin oligodendrocyte glycopro-tein. J Autoimmun 11:287-299.
-
(1998)
J Autoimmun
, vol.11
, pp. 287-299
-
-
De Rosbo, N.K.1
Ben-Nun, A.2
-
17
-
-
84871695430
-
Immune response during interferon beta-1b treatment in patients with multiple sclerosis who experienced relapses and those who were relapse-free in the START study
-
Dhib-Jalbut S, Sumandeep S, Valenzuela R, Ito K, Patel P, Rametta M. 2013. Immune response during interferon beta-1b treatment in patients with multiple sclerosis who experienced relapses and those who were relapse-free in the START study. J Neuroimmunol 254:131-140.
-
(2013)
J Neuroimmunol
, vol.254
, pp. 131-140
-
-
Dhib-Jalbut, S.1
Sumandeep, S.2
Valenzuela, R.3
Ito, K.4
Patel, P.5
Rametta, M.6
-
18
-
-
0032879769
-
Autoreactivity to myelin antigens: Myelin/oligodendro-cyte glycoprotein is a prevalent autoantigen
-
Diaz-Villoslada P, Shih A, Shao L, Genain CP, Hauser SL. 1999. Autoreactivity to myelin antigens: myelin/oligodendro-cyte glycoprotein is a prevalent autoantigen. J Neuroimmunol 99:36-43.
-
(1999)
J Neuroimmunol
, vol.99
, pp. 36-43
-
-
Diaz-Villoslada, P.1
Shih, A.2
Shao, L.3
Genain, C.P.4
Hauser, S.L.5
-
19
-
-
0024578770
-
Chronic relapsing experimental allergic encephalomyelitis in SJL mice following the adoptive transfer of an epitope-specific T cell line
-
Fallis RJ, Raine CS, McFarlin DE. 1989. Chronic relapsing experimental allergic encephalomyelitis in SJL mice following the adoptive transfer of an epitope-specific T cell line. J Neuroimmunol 22:93-105.
-
(1989)
J Neuroimmunol
, vol.22
, pp. 93-105
-
-
Fallis, R.J.1
Raine, C.S.2
McFarlin, D.E.3
-
20
-
-
70450184483
-
Serum levels of CXCL13 are elevated in active multiple sclerosis
-
Festa ED, Hankiewicz K, Kim S, Skurnick J, Wolansky LJ, Cook SD, and others. 2009. Serum levels of CXCL13 are elevated in active multiple sclerosis. Mult Scler 15:1271-1279.
-
(2009)
Mult Scler
, vol.15
, pp. 1271-1279
-
-
Festa, E.D.1
Hankiewicz, K.2
Kim, S.3
Skurnick, J.4
Wolansky, L.J.5
Cook, S.D.6
-
21
-
-
0345700237
-
Monocyte-derived IL12, CD86 (B7-2) and CD40L expression in relapsing and progressive multiple sclerosis
-
Filion LG, Matusevicius D, Graziani-Bowering GM, Kumar A, Freedman MS. 2003. Monocyte-derived IL12, CD86 (B7-2) and CD40L expression in relapsing and progressive multiple sclerosis. Clin Immunol 106:127-138.
-
(2003)
Clin Immunol
, vol.106
, pp. 127-138
-
-
Filion, L.G.1
Matusevicius, D.2
Graziani-Bowering, G.M.3
Kumar, A.4
Freedman, M.S.5
-
22
-
-
0031546005
-
Serial contrast-enhanced MR in patients with multiple sclerosis and varying levels of disability
-
Filippi M, Rossi P, Campi A, Colombo B, Pereira C, Comi G. 1997. Serial contrast-enhanced MR in patients with multiple sclerosis and varying levels of disability. AJNR Am J Neu-roradiol 18:1549-1556.
-
(1997)
AJNR Am J Neu-roradiol
, vol.18
, pp. 1549-1556
-
-
Filippi, M.1
Rossi, P.2
Campi, A.3
Colombo, B.4
Pereira, C.5
Comi, G.6
-
23
-
-
66549130329
-
The relation between inflammation and neurodegeneration in multiple sclerosis brains
-
Frischer JM, Bramow S, Dal-Bianco A, Lucchinetti CF, Rauschka H, Schmidbauer M, and others. 2009. The relation between inflammation and neurodegeneration in multiple sclerosis brains. Brain 132:1175-1189.
-
(2009)
Brain
, vol.132
, pp. 1175-1189
-
-
Frischer, J.M.1
Bramow, S.2
Dal-Bianco, A.3
Lucchinetti, C.F.4
Rauschka, H.5
Schmidbauer, M.6
-
24
-
-
84872106441
-
A novel data mining system points out hidden relationships between immunological markers in multiple sclerosis
-
Gironi M, Saresella M, Rovaris M, Vaghi M, Nemni R, Clerici M, and others. 2013. A novel data mining system points out hidden relationships between immunological markers in multiple sclerosis. Immun Ageing 10:1.
-
(2013)
Immun Ageing
, vol.10
, pp. 1
-
-
Gironi, M.1
Saresella, M.2
Rovaris, M.3
Vaghi, M.4
Nemni, R.5
Clerici, M.6
-
25
-
-
84879239117
-
Daclizumab high-yield process in relapsing-remitting multiple sclerosis (SELECT): A randomised, double-blind, placebo-controlled trial
-
Gold R, Giovannoni G, Selmaj K, Havrdova E, Montalban X, Radue EW, and others. 2013. Daclizumab high-yield process in relapsing-remitting multiple sclerosis (SELECT): a randomised, double-blind, placebo-controlled trial. Lancet 381:2167-2175.
-
(2013)
Lancet
, vol.381
, pp. 2167-2175
-
-
Gold, R.1
Giovannoni, G.2
Selmaj, K.3
Havrdova, E.4
Montalban, X.5
Radue, E.W.6
-
26
-
-
67349090563
-
Myelin pep-tides in multiple sclerosis
-
Grau-López L, Raïch D, Ramo-Tello C, Naranjo-Gómez M, Dàvalos A, Pujol-Borrell R, and others. 2009. Myelin pep-tides in multiple sclerosis. Autoimmun Rev 8:650-653.
-
(2009)
Autoimmun Rev
, vol.8
, pp. 650-653
-
-
Grau-López, L.1
Raïch, D.2
Ramo-Tello, C.3
Naranjo-Gómez, M.4
Dàvalos, A.5
Pujol-Borrell, R.6
-
27
-
-
51249090471
-
T helper cell type 1 (Th1), Th2 and Th17 responses to myelin basic protein and disease activity in multiple sclerosis
-
Hedegaard CJ, Krakauer M, Bendtzen K, Lund H, Sellebjerg F, Nielsen CH. 2008. T helper cell type 1 (Th1), Th2 and Th17 responses to myelin basic protein and disease activity in multiple sclerosis. Immunology 125:161-169.
-
(2008)
Immunology
, vol.125
, pp. 161-169
-
-
Hedegaard, C.J.1
Krakauer, M.2
Bendtzen, K.3
Lund, H.4
Sellebjerg, F.5
Nielsen, C.H.6
-
28
-
-
0035254476
-
T-cell reactivity to multiple myelin antigens in multiple sclerosis patients and healthy controls
-
Hellings N, Barée M, Verhoeven C, D'hooghe MB, Medaer R, Bernard CC, and others. 2001. T-cell reactivity to multiple myelin antigens in multiple sclerosis patients and healthy controls. J Neurosci Res 63:290-302.
-
(2001)
J Neurosci Res
, vol.63
, pp. 290-302
-
-
Hellings, N.1
Barée, M.2
Verhoeven, C.3
D'Hooghe, M.B.4
Medaer, R.5
Bernard, C.C.6
-
29
-
-
0036096668
-
Longitudinal study of antimyelin T-cell reactivity in relapsing-remitting multiple sclerosis: Association with clinical and MRI activity
-
Hellings N, Gelin G, Medaer R, Bruckers L, Palmers Y, Raus J, and others. 2002. Longitudinal study of antimyelin T-cell reactivity in relapsing-remitting multiple sclerosis: association with clinical and MRI activity. J Neuroimmunol 126: 143-160.
-
(2002)
J Neuroimmunol
, vol.126
, pp. 143-160
-
-
Hellings, N.1
Gelin, G.2
Medaer, R.3
Bruckers, L.4
Palmers, Y.5
Raus, J.6
-
30
-
-
79951677394
-
Fate mapping of IL-17-producing T cells in inflammatory responses
-
Hirota K, Duarte JH, Veldhoen M, Hornsby E, Li Y, Cua DJ, and others. 2011. Fate mapping of IL-17-producing T cells in inflammatory responses. Nat Immunol 12:255-263.
-
(2011)
Nat Immunol
, vol.12
, pp. 255-263
-
-
Hirota, K.1
Duarte, J.H.2
Veldhoen, M.3
Hornsby, E.4
Li, Y.5
Cua, D.J.6
-
31
-
-
79951743212
-
Functional specialization of interleukin-17 family members
-
Iwakura Y, Ishigame H, Saijo S, Nakae S. 2011. Functional specialization of interleukin-17 family members. Immunity 34:149-162.
-
(2011)
Immunity
, vol.34
, pp. 149-162
-
-
Iwakura, Y.1
Ishigame, H.2
Saijo, S.3
Nakae, S.4
-
32
-
-
33748510173
-
Innate immunity in multiple sclerosis: Myeloid dendritic cells in secondary progressive multiple sclerosis are activated and drive a proinflammatory immune response
-
Karni A, Abraham M, Monsonego A, Cai G, Freeman GJ, Hafler D, and others. 2006. Innate immunity in multiple sclerosis: myeloid dendritic cells in secondary progressive multiple sclerosis are activated and drive a proinflammatory immune response. J Immunol 177:4196-4202.
-
(2006)
J Immunol
, vol.177
, pp. 4196-4202
-
-
Karni, A.1
Abraham, M.2
Monsonego, A.3
Cai, G.4
Freeman, G.J.5
Hafler, D.6
-
33
-
-
0036229763
-
IL-18 is linked to raised IFN-gamma in multiple sclerosis and is induced by activated CD4(+ ) T cells via CD40-CD40 ligand interactions
-
Karni A, Koldzic DN, Bharanidharan P, Khoury SJ, Weiner HL. 2002. IL-18 is linked to raised IFN-gamma in multiple sclerosis and is induced by activated CD4(+ ) T cells via CD40-CD40 ligand interactions. J Neuroimmunol 125: 134-140.
-
(2002)
J Neuroimmunol
, vol.125
, pp. 134-140
-
-
Karni, A.1
Koldzic, D.N.2
Bharanidharan, P.3
Khoury, S.J.4
Weiner, H.L.5
-
34
-
-
70350052626
-
Preferential recruitment of interferon-gamma-expressing TH17 cells in multiple sclerosis
-
Kebir H, Ifergan I, Alvarez JI, Bernard M, Poirier J, Arbour N, and others. 2009. Preferential recruitment of interferon-gamma-expressing TH17 cells in multiple sclerosis. Ann Neurol 66:390-402.
-
(2009)
Ann Neurol
, vol.66
, pp. 390-402
-
-
Kebir, H.1
Ifergan, I.2
Alvarez, J.I.3
Bernard, M.4
Poirier, J.5
Arbour, N.6
-
35
-
-
79953179371
-
Cerebrospinal fluid CXCL13 in multiple sclerosis: A suggestive prognostic marker for the disease course
-
Khademi M, Kockum I, Andersson ML, Iacobaeus E, Brundin L, Sellebjerg F, and others. 2011. Cerebrospinal fluid CXCL13 in multiple sclerosis: a suggestive prognostic marker for the disease course. Mult Scler 17:335-343.
-
(2011)
Mult Scler
, vol.17
, pp. 335-343
-
-
Khademi, M.1
Kockum, I.2
Andersson, M.L.3
Iacobaeus, E.4
Brundin, L.5
Sellebjerg, F.6
-
36
-
-
79954611536
-
Differential effects of fingolimod (FTY720) on immune cells in the CSF and blood of patients with MS
-
Kowarik MC, Pellkofer HL, Cepok S, Korn T, Kümpfel T, Buck D, and others. 2011. Differential effects of fingolimod (FTY720) on immune cells in the CSF and blood of patients with MS. Neurology 76:1214-1221.
-
(2011)
Neurology
, vol.76
, pp. 1214-1221
-
-
Kowarik, M.C.1
Pellkofer, H.L.2
Cepok, S.3
Korn, T.4
Kümpfel, T.5
Buck, D.6
-
37
-
-
46949104323
-
IL-12-and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition
-
Kroenke MA, Carlson TJ, Andjelkovic AV, Segal BM. 2008. IL-12-and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition. J Exp Med 205:1535-1541.
-
(2008)
J Exp Med
, vol.205
, pp. 1535-1541
-
-
Kroenke, M.A.1
Carlson, T.J.2
Andjelkovic, A.V.3
Segal, B.M.4
-
38
-
-
30344446249
-
Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitment
-
Krumbholz M, Theil D, Cepok S, Hemmer B, Kivisäkk P, Ransohoff RM, and others. 2006. Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitment. Brain 129: 200-211.
-
(2006)
Brain
, vol.129
, pp. 200-211
-
-
Krumbholz, M.1
Theil, D.2
Cepok, S.3
Hemmer, B.4
Kivisäkk, P.5
Ransohoff, R.M.6
-
39
-
-
27644552194
-
Cortical de-myelination and diffuse white matter injury in multiple sclerosis
-
Kutzelnigg A, Lucchinetti CF, Stadelmann C, Brück W, Rauschka H, Bergmann M, and others. 2005. Cortical de-myelination and diffuse white matter injury in multiple sclerosis. Brain 128:2705-2712.
-
(2005)
Brain
, vol.128
, pp. 2705-2712
-
-
Kutzelnigg, A.1
Lucchinetti, C.F.2
Stadelmann, C.3
Brück, W.4
Rauschka, H.5
Bergmann, M.6
-
40
-
-
84872914335
-
Longitudinal interferon-b effects in multiple sclerosis: Differential regulation of IL-10 and IL-17A, while no sustained effects on IFN-g, IL-4 or IL-13
-
Kvarnström M, Ydrefors J, Ekerfelt C, Vrethem M, Ernerudh J. 2013. Longitudinal interferon-b effects in multiple sclerosis: differential regulation of IL-10 and IL-17A, while no sustained effects on IFN-g, IL-4 or IL-13. J Neurol Sci 325: 79-85.
-
(2013)
J Neurol Sci
, vol.325
, pp. 79-85
-
-
Kvarnström, M.1
Ydrefors, J.2
Ekerfelt, C.3
Vrethem, M.4
Ernerudh, J.5
-
41
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
Langrish CL, Chen Y, Blumenschein WM, Mattson J, Basham B, Sedgwick JD, and others. 2005. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 201:233-240.
-
(2005)
J Exp Med
, vol.201
, pp. 233-240
-
-
Langrish, C.L.1
Chen, Y.2
Blumenschein, W.M.3
Mattson, J.4
Basham, B.5
Sedgwick, J.D.6
-
42
-
-
77955656367
-
Axonal and neuronal pathology in multiple sclerosis: What have we learnt from animal models
-
Lassmann H. 2010. Axonal and neuronal pathology in multiple sclerosis: what have we learnt from animal models. Exp Neurol 225:2-8.
-
(2010)
Exp Neurol
, vol.225
, pp. 2-8
-
-
Lassmann, H.1
-
43
-
-
34249700046
-
Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology
-
Magliozzi R, Howell O, Vora A, Serafini B, Nicholas R, Puo-polo M, and others. 2007. Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology. Brain 130: 1089-1104.
-
(2007)
Brain
, vol.130
, pp. 1089-1104
-
-
Magliozzi, R.1
Howell, O.2
Vora, A.3
Serafini, B.4
Nicholas, R.5
Puo-Polo, M.6
-
44
-
-
0142043832
-
Interferon gamma responses to myelin peptides in multiple sclerosis correlate with a new clinical measure of disease progression
-
Moldovan IR, Rudick RA, Cotleur AC, Born SE, Lee JC, Karafa MT, and others. 2003. Interferon gamma responses to myelin peptides in multiple sclerosis correlate with a new clinical measure of disease progression. J Neuroimmunol 141:132-140.
-
(2003)
J Neuroimmunol
, vol.141
, pp. 132-140
-
-
Moldovan, I.R.1
Rudick, R.A.2
Cotleur, A.C.3
Born, S.E.4
Lee, J.C.5
Karafa, M.T.6
-
45
-
-
20144364415
-
Longitudinal single-cell cyto-kine responses reveal recurrent autoimmune myelin reactivity in relapsing-remitting multiple sclerosis patients
-
Moldovan IR, Rudick RA, Cotleur AC, Born SE, Lee JC, Karafa MT, and others. 2005. Longitudinal single-cell cyto-kine responses reveal recurrent autoimmune myelin reactivity in relapsing-remitting multiple sclerosis patients. Mult Scler 11:251-260.
-
(2005)
Mult Scler
, vol.11
, pp. 251-260
-
-
Moldovan, I.R.1
Rudick, R.A.2
Cotleur, A.C.3
Born, S.E.4
Lee, J.C.5
Karafa, M.T.6
-
46
-
-
0029762023
-
Review: Cytokines and the patho-genesis of multiple sclerosis
-
Navikas V, Link H. 1996. Review: cytokines and the patho-genesis of multiple sclerosis. J Neurosci Res 45:322-333.
-
(1996)
J Neurosci Res
, vol.45
, pp. 322-333
-
-
Navikas, V.1
Link, H.2
-
47
-
-
0025314243
-
Interrater variability with the Expanded Disability Status Scale (EDSS) and Functional Systems (FS) in a multiple sclerosis clinical trial. The Canadian Cooperation MS Study Group
-
Noseworthy JH, Vandervoort MK, Wong CJ, Ebers GC. 1990. Interrater variability with the Expanded Disability Status Scale (EDSS) and Functional Systems (FS) in a multiple sclerosis clinical trial. The Canadian Cooperation MS Study Group. Neurology 40:971-975.
-
(1990)
Neurology
, vol.40
, pp. 971-975
-
-
Noseworthy, J.H.1
Vandervoort, M.K.2
Wong, C.J.3
Ebers, G.C.4
-
48
-
-
0033638507
-
Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
-
Oppmann B, Lesley R, Blom B, Timans JC, Xu Y, Hunte B, and others. 2000. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity 13:715-725.
-
(2000)
Immunity
, vol.13
, pp. 715-725
-
-
Oppmann, B.1
Lesley, R.2
Blom, B.3
Timans, J.C.4
Xu, Y.5
Hunte, B.6
-
49
-
-
41549135632
-
The biological functions of T helper 17 cell effector cytokines in inflammation
-
Ouyang W, Kolls JK, Zheng Y. 2008. The biological functions of T helper 17 cell effector cytokines in inflammation. Immunity 28:454-467.
-
(2008)
Immunity
, vol.28
, pp. 454-467
-
-
Ouyang, W.1
Kolls, J.K.2
Zheng, Y.3
-
50
-
-
8844222623
-
Interferon beta-1b in secondary progressive MS: Results from a 3-year controlled study
-
Panitch H, Miller A, Paty D, Weinshenker B. 2004. Interferon beta-1b in secondary progressive MS: results from a 3-year controlled study. Neurology 63:1788-1795.
-
(2004)
Neurology
, vol.63
, pp. 1788-1795
-
-
Panitch, H.1
Miller, A.2
Paty, D.3
Weinshenker, B.4
-
51
-
-
0033546980
-
Quantitative MRI in patients with secondary progressive MS treated with monoclonal antibody Campath 1H
-
Paolillo A, Coles AJ, Molyneux PD, Gawne-Cain M, MacManus D, Barker GJ, and others. 1999. Quantitative MRI in patients with secondary progressive MS treated with monoclonal antibody Campath 1H. Neurology 53: 751-757.
-
(1999)
Neurology
, vol.53
, pp. 751-757
-
-
Paolillo, A.1
Coles, A.J.2
Molyneux, P.D.3
Gawne-Cain, M.4
MacManus, D.5
Barker, G.J.6
-
52
-
-
0034326642
-
Surges of increased T cell reactivity to an encephalitogenic region of myelin proteolipid protein occur more often in patients with multiple sclerosis than in healthy subjects
-
Pender MP, Csurhes PA, Greer JM, Mowat PD, Henderson RD, Cameron KD, and others. 2000. Surges of increased T cell reactivity to an encephalitogenic region of myelin proteolipid protein occur more often in patients with multiple sclerosis than in healthy subjects. J Immunol 165: 5322-5331.
-
(2000)
J Immunol
, vol.165
, pp. 5322-5331
-
-
Pender, M.P.1
Csurhes, P.A.2
Greer, J.M.3
Mowat, P.D.4
Henderson, R.D.5
Cameron, K.D.6
-
53
-
-
84355166761
-
Th17 cells induce ectopic lym-phoid follicles in central nervous system tissue inflammation
-
Peters A, Pitcher LA, Sullivan JM, Mitsdoerffer M, Acton SE, Franz B, and others. 2011. Th17 cells induce ectopic lym-phoid follicles in central nervous system tissue inflammation. Immunity 35:986-996.
-
(2011)
Immunity
, vol.35
, pp. 986-996
-
-
Peters, A.1
Pitcher, L.A.2
Sullivan, J.M.3
Mitsdoerffer, M.4
Acton, S.E.5
Franz, B.6
-
54
-
-
77953341196
-
Changes in B-and T-lymphocyte and chemokine levels with rituximab treatment in multiple sclerosis
-
Piccio L, Naismith RT, Trinkaus K, Klein RS, Parks BJ, Lyons JA, and others. 2010. Changes in B-and T-lymphocyte and chemokine levels with rituximab treatment in multiple sclerosis. Arch Neurol 67:707-714.
-
(2010)
Arch Neurol
, vol.67
, pp. 707-714
-
-
Piccio, L.1
Naismith, R.T.2
Trinkaus, K.3
Klein, R.S.4
Parks, B.J.5
Lyons, J.A.6
-
55
-
-
33644584352
-
A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis
-
Polman CH, O'Connor PW, Havrdova E, Hutchinson M, Kappos L, Miller DH, and others. 2006. A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis. N Engl J Med 354:899-910.
-
(2006)
N Engl J Med
, vol.354
, pp. 899-910
-
-
Polman, C.H.1
O'Connor, P.W.2
Havrdova, E.3
Hutchinson, M.4
Kappos, L.5
Miller, D.H.6
-
56
-
-
0018760184
-
Multiple sclerosis: Presence of lymphatic capillaries and lymphoid tissue in the brain and spinal cord
-
Prineas JW. 1979. Multiple sclerosis: presence of lymphatic capillaries and lymphoid tissue in the brain and spinal cord. Science 203:1123-1125.
-
(1979)
Science
, vol.203
, pp. 1123-1125
-
-
Prineas, J.W.1
-
57
-
-
79959494654
-
Multiple sclerosis: BAFF and CXCL13 in cerebrospinal fluid
-
Ragheb S, Li Y, Simon K, VanHaerents S, Galimberti D, De Riz M, and others. 2011. Multiple sclerosis: BAFF and CXCL13 in cerebrospinal fluid. Mult Scler 17:819-829.
-
(2011)
Mult Scler
, vol.17
, pp. 819-829
-
-
Ragheb, S.1
Li, Y.2
Simon, K.3
Vanhaerents, S.4
Galimberti, D.5
De Riz, M.6
-
58
-
-
84878347050
-
CSF inflammation and axonal damage are increased and correlate in progressive multiple sclerosis
-
Romme Christensen J, Börnsen L, Khademi M, Olsson T, Jensen PE, Sørensen PS, and others. 2013. CSF inflammation and axonal damage are increased and correlate in progressive multiple sclerosis. Mult Scler 19:877-884.
-
(2013)
Mult Scler
, vol.19
, pp. 877-884
-
-
Romme Christensen, J.1
Börnsen, L.2
Khademi, M.3
Olsson, T.4
Jensen, P.E.5
Sørensen, P.S.6
-
59
-
-
0031816173
-
In vivo effects of interferon beta-1a on immunosuppressive cytokines in multiple sclerosis
-
Rudick RA, Ransohoff RM, Lee JC, Peppler R, Yu M, Mathisen PM, and others. 1998. In vivo effects of interferon beta-1a on immunosuppressive cytokines in multiple sclerosis. Neurology 50:1294-1300.
-
(1998)
Neurology
, vol.50
, pp. 1294-1300
-
-
Rudick, R.A.1
Ransohoff, R.M.2
Lee, J.C.3
Peppler, R.4
Yu, M.5
Mathisen, P.M.6
-
60
-
-
0022447418
-
Studies of experimental allergic encephalomy-elitis by using encephalitogenic T cell lines and clones in euthymic and athymic mice
-
Sakai K, Namikawa T, Kunishita T, Yamanouchi K, Tabira T. 1986. Studies of experimental allergic encephalomy-elitis by using encephalitogenic T cell lines and clones in euthymic and athymic mice. J Immunol 137:1527-1531.
-
(1986)
J Immunol
, vol.137
, pp. 1527-1531
-
-
Sakai, K.1
Namikawa, T.2
Kunishita, T.3
Yamanouchi, K.4
Tabira, T.5
-
61
-
-
80051684615
-
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
-
Sawcer S, Hellenthal G, Pirinen M, Spencer CC, Patsopoulos NA, Moutsianas L, and others. 2011. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature 476:214-219.
-
(2011)
Nature
, vol.476
, pp. 214-219
-
-
Sawcer, S.1
Hellenthal, G.2
Pirinen, M.3
Spencer, C.C.4
Patsopoulos, N.A.5
Moutsianas, L.6
-
62
-
-
73349109797
-
Increased cerebrospinal fluid concentrations of the chemokine CXCL13 in active MS
-
Sellebjerg F, Börnsen L, Khademi M, Krakauer M, Olsson T, Frederiksen JL, and others. 2009. Increased cerebrospinal fluid concentrations of the chemokine CXCL13 in active MS. Neurology 73:2003-2010.
-
(2009)
Neurology
, vol.73
, pp. 2003-2010
-
-
Sellebjerg, F.1
Börnsen, L.2
Khademi, M.3
Krakauer, M.4
Olsson, T.5
Frederiksen, J.L.6
-
63
-
-
2442708947
-
Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis
-
Serafini B, Rosicarelli B, Magliozzi R, Stigliano E, Aloisi F. 2004. Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis. Brain Pathol 14:164-174.
-
(2004)
Brain Pathol
, vol.14
, pp. 164-174
-
-
Serafini, B.1
Rosicarelli, B.2
Magliozzi, R.3
Stigliano, E.4
Aloisi, F.5
-
64
-
-
33745728404
-
How to successfully apply animal studies in experimental allergic encephalomyelitis to research on multiple sclerosis
-
Steinman L, Zamvil SS. 2006. How to successfully apply animal studies in experimental allergic encephalomyelitis to research on multiple sclerosis. Ann Neurol 60:12-21.
-
(2006)
Ann Neurol
, vol.60
, pp. 12-21
-
-
Steinman, L.1
Zamvil, S.S.2
-
65
-
-
53049107590
-
The effects of natalizumab on the innate and adaptive immune system in the central nervous system
-
Stüve O. 2008. The effects of natalizumab on the innate and adaptive immune system in the central nervous system. J Neurol Sci 274:39-41.
-
(2008)
J Neurol Sci
, vol.274
, pp. 39-41
-
-
Stüve, O.1
-
66
-
-
48249139449
-
Multiple sclerosis: An immune or neurodegenerative disorder?
-
Trapp BD, Nave KA. 2008. Multiple sclerosis: an immune or neurodegenerative disorder? Annu Rev Neurosci 31:247-269.
-
(2008)
Annu Rev Neurosci
, vol.31
, pp. 247-269
-
-
Trapp, B.D.1
Nave, K.A.2
-
67
-
-
38749143286
-
Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis
-
Tzartos JS, Friese MA, Craner MJ, Palace J, Newcombe J, Esiri MM, and others. 2008. Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis. Am J Pathol 172: 146-155.
-
(2008)
Am J Pathol
, vol.172
, pp. 146-155
-
-
Tzartos, J.S.1
Friese, M.A.2
Craner, M.J.3
Palace, J.4
Newcombe, J.5
Esiri, M.M.6
-
68
-
-
33847241851
-
Sensitivity of immediate and delayed gadolinium-enhanced MRI after injection of 0.5 M and 1.0M gadolinium chelates for detecting multiple sclerosis lesions
-
Uysal E, Erturk SM, Yildirim H, Seleker F, Basak M. 2007. Sensitivity of immediate and delayed gadolinium-enhanced MRI after injection of 0.5 M and 1.0M gadolinium chelates for detecting multiple sclerosis lesions. AJR Am J Roent-genol 188:697-702.
-
(2007)
AJR Am J Roent-genol
, vol.188
, pp. 697-702
-
-
Uysal, E.1
Erturk, S.M.2
Yildirim, H.3
Seleker, F.4
Basak, M.5
-
69
-
-
80155211551
-
Interleukin 2 receptor a gene polymorphism and risk of multiple sclerosis: A meta-analysis
-
Wang LM, Zhang DM, Xu YM, Sun SL. 2011. Interleukin 2 receptor a gene polymorphism and risk of multiple sclerosis: a meta-analysis. J Int Med Res 39:1625-1635.
-
(2011)
J Int Med Res
, vol.39
, pp. 1625-1635
-
-
Wang, L.M.1
Zhang, D.M.2
Xu, Y.M.3
Sun, S.L.4
-
70
-
-
0035205741
-
Relationship between serum levels of IL-10, MRI activity and interferon beta-1a therapy in patients with relapsing remitting MS
-
Waubant E, Gee L, Bacchetti P, Sloan R, Cotleur A, Rudick R, and others. 2001. Relationship between serum levels of IL-10, MRI activity and interferon beta-1a therapy in patients with relapsing remitting MS. J Neuroimmunol 112:139-145.
-
(2001)
J Neuroimmunol
, vol.112
, pp. 139-145
-
-
Waubant, E.1
Gee, L.2
Bacchetti, P.3
Sloan, R.4
Cotleur, A.5
Rudick, R.6
-
71
-
-
40349096095
-
A shift from adaptive to innate immunity: A potential mechanism of disease progression in multiple sclerosis
-
Weiner HL. 2008. A shift from adaptive to innate immunity: a potential mechanism of disease progression in multiple sclerosis. J Neurol 255 Suppl 1:3-11.
-
(2008)
J Neurol
, vol.255
, Issue.SUPPL. 1
, pp. 3-11
-
-
Weiner, H.L.1
-
72
-
-
77951626389
-
Genetic variation in the IL7RA/IL7 pathway increases multiple sclerosis susceptibility
-
Zuvich RL, McCauley JL, Oksenberg JR, Sawcer SJ, De Jager PL, Aubin C, and others. 2010. Genetic variation in the IL7RA/IL7 pathway increases multiple sclerosis susceptibility. Hum Genet 127:525-535.
-
(2010)
Hum Genet
, vol.127
, pp. 525-535
-
-
Zuvich, R.L.1
McCauley, J.L.2
Oksenberg, J.R.3
Sawcer, S.J.4
De Jager, P.L.5
Aubin, C.6
|