-
1
-
-
76149140914
-
Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis
-
Cohen JA, Barkhof F, Comi G, et al. Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis. N Engl J Med 2010;362:402-415.
-
(2010)
N Engl J Med
, vol.362
, pp. 402-415
-
-
Cohen, J.A.1
Barkhof, F.2
Comi, G.3
-
2
-
-
77955799815
-
Oral fingolimod (FTY720) for relapsing multiple sclerosis
-
DOI 10.1056/NEJMoa052643
-
Kappos L, Antel J, Comi G, et al. Oral fingolimod (FTY720) for relapsing multiple sclerosis. N Engl J Med 2006;355:1124-1140. (Pubitemid 44394919)
-
(2006)
New England Journal of Medicine
, vol.355
, Issue.11
, pp. 1124-1140
-
-
Kappos, L.1
Antel, J.2
Comi, G.3
Montalban, X.4
O'Connor, P.5
Polman, C.H.6
Haas, T.7
Korn, A.A.8
Karlsson, G.9
Radue, E.W.10
-
3
-
-
0037066466
-
Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists
-
DOI 10.1126/science.1070238
-
Mandala S, Hajdu R, Bergstrom J, et al. Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists. Science 2002;296:346-349. (Pubitemid 34303689)
-
(2002)
Science
, vol.296
, Issue.5566
, pp. 346-349
-
-
Mandala, S.1
Hajdu, R.2
Bergstrom, J.3
Quackenbush, E.4
Xie, J.5
Milligan, J.6
Thornton, R.7
Shei, G.-J.8
Card, D.9
Keohane, C.10
Rosenbach, M.11
Hale, J.12
Lynch, C.L.13
Rupprecht, K.14
Parsons, W.15
Rosen, H.16
-
4
-
-
1642580757
-
Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
-
DOI 10.1038/nature02284
-
Matloubian M, Lo CG, Cinamon G, et al. Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1. Nature 2004;427:355-360. (Pubitemid 38133663)
-
(2004)
Nature
, vol.427
, Issue.6972
, pp. 355-360
-
-
Matloubian, M.1
Lo, C.G.2
Cinamon, G.3
Lesneski, M.J.4
Xu, Y.5
Brinkmann, V.6
Allende, M.L.7
Proia, R.L.8
Cyster, J.G.9
-
5
-
-
0030248747
-
Immunosuppressive effect of a new drug, FTY720, on lymphocyte responses in vitro and cardiac allograft survival in rats
-
DOI 10.1016/S0966-3274(96)80026-8
-
Suzuki S, Enosawa S, Kakefuda T, et al. Immunosuppressive effect of a new drug, FTY720, on lymphocyte responses in vitro and cardiac allograft survival in rats. Transpl Immunol 1996;4:252-255. (Pubitemid 26340578)
-
(1996)
Transplant Immunology
, vol.4
, Issue.3
, pp. 252-255
-
-
Suzuki, S.1
Enosawa, S.2
Kakefuda, T.3
Li, X.-K.4
Mitsusada, M.5
Takahara, S.6
Amemiya, H.7
-
6
-
-
0032525049
-
FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats. I. FTY720 selectively decreases the number of circulating mature lymphocytes by acceleration of lymphocyte homing
-
Chiba K, Yanagawa Y, Masubuchi Y, et al. FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats: I: FTY720 selectively decreases the number of circulating mature lymphocytes by acceleration of lymphocyte homing. J Immunol 1998;160:5037-5044. (Pubitemid 28215340)
-
(1998)
Journal of Immunology
, vol.160
, Issue.10
, pp. 5037-5044
-
-
Chiba, K.1
Yanagawa, Y.2
Masubuchi, Y.3
Kataoka, H.4
Kawaguchi, T.5
Ohtsuki, M.6
Hoshino, Y.7
-
7
-
-
33748695513
-
Fingolimod and sphingosine-1-phosphate - Modifiers of lymphocyte migration
-
DOI 10.1056/NEJMp068159
-
Massberg S, von Andrian UH. Fingolimod and sphingosine- 1-phosphate: modifiers of lymphocyte migration. N Engl J Med 2006;355:1088-1091. (Pubitemid 44394915)
-
(2006)
New England Journal of Medicine
, vol.355
, Issue.11
, pp. 1088-1091
-
-
Massberg, S.1
Von Andrian, U.H.2
-
8
-
-
1342306184
-
FTY720 exerts differential effects on CD4- and CD8-T-lymphocyte subpopulations expressing chemokine and adhesion receptors
-
Bohler T, Waiser J, Schuetz M, Neumayer HH, Budde K. FTY720 exerts differential effects on CD4-and CD8-T-lymphocyte subpopulations expressing chemokine and adhesion receptors. Nephrol Dial Transplant 2004;19: 702-713.
-
(2004)
Nephrol Dial Transplant
, vol.19
, pp. 702-713
-
-
Bohler, T.1
Waiser, J.2
Schuetz, M.3
Neumayer, H.H.4
Budde, K.5
-
9
-
-
33749588466
-
Altered CD4-/ CD8-T-cell ratios in cerebrospinal fluid of natalizumabtreated patients with multiple sclerosis
-
Stuve O, Marra CM, Bar-Or A, et al. Altered CD4-/ CD8-T-cell ratios in cerebrospinal fluid of natalizumabtreated patients with multiple sclerosis. Arch Neurol 2006; 63:1383-1387.
-
(2006)
Arch Neurol
, vol.63
, pp. 1383-1387
-
-
Stuve, O.1
Marra, C.M.2
Bar-Or, A.3
-
10
-
-
33646347610
-
Immune surveillance in multiple sclerosis patients treated with natalizumab
-
DOI 10.1002/ana.20858
-
Stuve O, Marra CM, Jerome KR, et al. Immune surveillance in multiple sclerosis patients treated with natalizumab. Ann Neurol 2006;59:743-747. (Pubitemid 43673151)
-
(2006)
Annals of Neurology
, vol.59
, Issue.5
, pp. 743-747
-
-
Stuve, O.1
Marra, C.M.2
Jerome, K.R.3
Cook, L.4
Cravens, P.D.5
Cepok, S.6
Frohman, E.M.7
Phillips, T.8
Arendt, G.9
Hemmer, B.10
Monson, N.L.11
Racke, M.K.12
-
11
-
-
33750605554
-
Accumulation of class switched IgD-IgM- memory B cells in the cerebrospinal fluid during neuroinflammation
-
DOI 10.1016/j.jneuroim.2006.06.031, PII S0165572806002724
-
Cepok S, von Geldern G, Grummel V, et al. Accumulation of class switched IgD-IgM- memory B cells in the cerebrospinal fluid during neuroinflammation. J Neuroimmunol 2006;180:33-39. (Pubitemid 44692322)
-
(2006)
Journal of Neuroimmunology
, vol.180
, Issue.1-2
, pp. 33-39
-
-
Cepok, S.1
Von Geldern, G.2
Grummel, V.3
Hochgesand, S.4
Celik, H.5
Hartung, H.6
Hemmer, B.7
-
12
-
-
55449137632
-
Natalizumab disproportionately increases circulating pre-B and B cells in multiple sclerosis
-
Krumbholz M, Meinl I, Kumpfel T, Hohlfeld R, Meinl E. Natalizumab disproportionately increases circulating pre-B and B cells in multiple sclerosis. Neurology 2008;71: 1350-1354.
-
(2008)
Neurology
, vol.71
, pp. 1350-1354
-
-
Krumbholz, M.1
Meinl, I.2
Kumpfel, T.3
Hohlfeld, R.4
Meinl, E.5
-
13
-
-
33646098169
-
FTY720 treatment of kidney transplant patients: A differential effect on B cells, naive T cells, memory T cells and NK cells
-
Vaessen LM, Van Besouw NM, Mol WM, Ijzermans JN, Weimar W. FTY720 treatment of kidney transplant patients: a differential effect on B cells, naive T cells, memory T cells and NK cells. Transpl Immunol 2006;15:281-288.
-
(2006)
Transpl Immunol
, vol.15
, pp. 281-288
-
-
Vaessen, L.M.1
Van Besouw, N.M.2
Mol, W.M.3
Ijzermans, J.N.4
Weimar, W.5
-
14
-
-
3242796768
-
Sphingosine 1-phosphate receptor 1 promotes B cell localization in the splenic marginal zone
-
DOI 10.1038/ni1083
-
Cinamon G, Matloubian M, Lesneski MJ, et al. Sphingosine 1-phosphate receptor 1 promotes B cell localization in the splenic marginal zone. Nat Immunol 2004;5:713-720. (Pubitemid 39023303)
-
(2004)
Nature Immunology
, vol.5
, Issue.7
, pp. 713-720
-
-
Cinamon, G.1
Matloubian, M.2
Lesneski, M.J.3
Xu, Y.4
Low, C.5
Lu, T.6
Proia, R.L.7
Cyster, J.G.8
-
15
-
-
54449099880
-
FTY720 therapy exerts differential effects on T cell subsets in multiple sclerosis
-
Mehling M, Brinkmann V, Antel J, et al. FTY720 therapy exerts differential effects on T cell subsets in multiple sclerosis. Neurology 2008;71:1261-1267.
-
(2008)
Neurology
, vol.71
, pp. 1261-1267
-
-
Mehling, M.1
Brinkmann, V.2
Antel, J.3
-
16
-
-
33747837449
-
Physiologically based pharmacokinetic modeling of FTY720 (2-amino-2[2-(-4-octylphenyl)ethyl]propane-1,3-diol hydrochloride) in rats after oral and intravenous doses
-
DOI 10.1124/dmd.105.009001
-
Meno-Tetang GM, Li H, Mis S, et al. Physiologically based pharmacokinetic modeling of FTY720 (2-amino- 2[2-(-4-octylphenyl)ethyl]propane-1,3-diol hydrochloride) in rats after oral and intravenous doses. Drug Metab Dispos 2006;34:1480-1487. (Pubitemid 44285388)
-
(2006)
Drug Metabolism and Disposition
, vol.34
, Issue.9
, pp. 1480-1487
-
-
Meno-Tetang, G.M.L.1
Li, H.2
Mis, S.3
Pyszczynski, N.4
Heining, P.5
Lowe, P.6
Jusko, W.J.7
|