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Volumn 19, Issue 7, 2013, Pages 877-884

CSF inflammation and axonal damage are increased and correlate in progressive multiple sclerosis

Author keywords

axonal damage; cerebrospinal fluid; demyelination; ELISA; inflammation; Multiple sclerosis; oxidative stress

Indexed keywords

CXCL13 CHEMOKINE; DIRUCOTIDE; GELATINASE B; OSTEOPONTIN;

EID: 84878347050     PISSN: 13524585     EISSN: 14770970     Source Type: Journal    
DOI: 10.1177/1352458512466929     Document Type: Article
Times cited : (72)

References (36)
  • 1
    • 0034676548 scopus 로고    scopus 로고
    • Relapses and progression of disability in multiple sclerosis
    • Confavreux C, Vukusic S, Moreau T, et al. Relapses and progression of disability in multiple sclerosis. N Engl J Med. 2000 ; 343: 1430-1438
    • (2000) N Engl J Med , vol.343 , pp. 1430-1438
    • Confavreux, C.1    Vukusic, S.2    Moreau, T.3
  • 2
    • 82255160649 scopus 로고    scopus 로고
    • Age and disability accumulation in multiple sclerosis
    • Scalfari A, Neuhaus A, Daumer M, et al. Age and disability accumulation in multiple sclerosis. Neurology. 2011 ; 77: 1246-1252
    • (2011) Neurology , vol.77 , pp. 1246-1252
    • Scalfari, A.1    Neuhaus, A.2    Daumer, M.3
  • 3
    • 73449124392 scopus 로고    scopus 로고
    • Progressive multiple sclerosis
    • Bradl M, Lassmann H.. Progressive multiple sclerosis. Semin Immunopathol. 2009 ; 31: 455-465
    • (2009) Semin Immunopathol , vol.31 , pp. 455-465
    • Bradl, M.1    Lassmann, H.2
  • 4
    • 27644552194 scopus 로고    scopus 로고
    • Cortical demyelination and diffuse white matter injury in multiple sclerosis
    • Kutzelnigg A, Lucchinetti CF, Stadelmann C, et al. Cortical demyelination and diffuse white matter injury in multiple sclerosis. Brain. 2005 ; 128 (Pt 11). 2705-2712
    • (2005) Brain , vol.128 , Issue.PART 11 , pp. 2705-2712
    • Kutzelnigg, A.1    Lucchinetti, C.F.2    Stadelmann, C.3
  • 5
    • 33847227721 scopus 로고    scopus 로고
    • Widespread demyelination in the cerebellar cortex in multiple sclerosis
    • Kutzelnigg A, Faber-Rod JC, Bauer J, et al. Widespread demyelination in the cerebellar cortex in multiple sclerosis. Brain Pathol. 2007 ; 17: 38-44
    • (2007) Brain Pathol , vol.17 , pp. 38-44
    • Kutzelnigg, A.1    Faber-Rod, J.C.2    Bauer, J.3
  • 6
    • 0033870097 scopus 로고    scopus 로고
    • Multiple sclerosis and chronic autoimmune encephalomyelitis: A comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions
    • Kornek B, Storch MK, Weissert R, et al. Multiple sclerosis and chronic autoimmune encephalomyelitis: A comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions. Am J Pathol. 2000 ; 157: 267-276
    • (2000) Am J Pathol , vol.157 , pp. 267-276
    • Kornek, B.1    Storch, M.K.2    Weissert, R.3
  • 7
    • 66549130329 scopus 로고    scopus 로고
    • The relation between inflammation and neurodegeneration in multiple sclerosis brains
    • Frischer JM, Bramow S, Dal-Bianco A, et al. The relation between inflammation and neurodegeneration in multiple sclerosis brains. Brain. 2009 ; 132 (Pt 5). 1175-1189
    • (2009) Brain , vol.132 , Issue.PART 5 , pp. 1175-1189
    • Frischer, J.M.1    Bramow, S.2    Dal-Bianco, A.3
  • 8
    • 80052927697 scopus 로고    scopus 로고
    • Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis
    • Howell OW, Reeves CA, Nicholas R, et al. Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis. Brain. 2011 ; 134 (Pt 9). 2755-2771
    • (2011) Brain , vol.134 , Issue.PART 9 , pp. 2755-2771
    • Howell, O.W.1    Reeves, C.A.2    Nicholas, R.3
  • 9
    • 54149084585 scopus 로고    scopus 로고
    • Multiple sclerosis
    • Compston A, Coles A.. Multiple sclerosis. Lancet. 2008 ; 372: 1502-1517
    • (2008) Lancet , vol.372 , pp. 1502-1517
    • Compston, A.1    Coles, A.2
  • 10
    • 81555223903 scopus 로고    scopus 로고
    • The molecular basis of neurodegeneration in multiple sclerosis
    • Lassmann H, van Horssen J.. The molecular basis of neurodegeneration in multiple sclerosis. FEBS Lett. 2011 ; 585: 3715-3723
    • (2011) FEBS Lett , vol.585 , pp. 3715-3723
    • Lassmann, H.1    Van Horssen, J.2
  • 11
    • 22444447949 scopus 로고    scopus 로고
    • Primary progressive multiple sclerosis: Current and future treatment options
    • Leary SM, Thompson AJ.. Primary progressive multiple sclerosis: Current and future treatment options. CNS Drugs. 19: 369-376
    • CNS Drugs , vol.19 , pp. 369-376
    • Leary, S.M.1    Thompson, A.J.2
  • 12
    • 33644974688 scopus 로고    scopus 로고
    • Secondary progressive multiple sclerosis: Current knowledge and future challenges
    • Rovaris M, Confavreux C, Furlan R, et al. Secondary progressive multiple sclerosis: Current knowledge and future challenges. Lancet Neurol. 2006 ; 5: 343-354
    • (2006) Lancet Neurol , vol.5 , pp. 343-354
    • Rovaris, M.1    Confavreux, C.2    Furlan, R.3
  • 13
    • 73349109797 scopus 로고    scopus 로고
    • Increased cerebrospinal fluid concentrations of the chemokine CXCL13 in active MS
    • Sellebjerg F, Bornsen L, Khademi M, et al. Increased cerebrospinal fluid concentrations of the chemokine CXCL13 in active MS. Neurology. 2009 ; 73: 2003-2010
    • (2009) Neurology , vol.73 , pp. 2003-2010
    • Sellebjerg, F.1    Bornsen, L.2    Khademi, M.3
  • 14
    • 78650973099 scopus 로고    scopus 로고
    • Osteopontin concentrations are increased in cerebrospinal fluid during attacks of multiple sclerosis
    • Bornsen L, Khademi M, Olsson T, et al. Osteopontin concentrations are increased in cerebrospinal fluid during attacks of multiple sclerosis. Mult Scler. 2011 ; 17: 32-42
    • (2011) Mult Scler , vol.17 , pp. 32-42
    • Bornsen, L.1    Khademi, M.2    Olsson, T.3
  • 15
    • 0346103689 scopus 로고    scopus 로고
    • Neurofilament light protein and glial fibrillary acidic protein as biological markers in MS
    • Malmestrom C, Haghighi S, Rosengren L, et al. Neurofilament light protein and glial fibrillary acidic protein as biological markers in MS. Neurology. 2003 ; 61: 1720-1725
    • (2003) Neurology , vol.61 , pp. 1720-1725
    • Malmestrom, C.1    Haghighi, S.2    Rosengren, L.3
  • 16
    • 12444288619 scopus 로고    scopus 로고
    • Axonal damage accumulates in the progressive phase of multiple sclerosis: Three year follow up study
    • Petzold A, Eikelenboom MJ, Keir G, et al. Axonal damage accumulates in the progressive phase of multiple sclerosis: Three year follow up study. J Neurol Neurosurg Psychiatry. 2005 ; 76: 206-211
    • (2005) J Neurol Neurosurg Psychiatry , vol.76 , pp. 206-211
    • Petzold, A.1    Eikelenboom, M.J.2    Keir, G.3
  • 17
    • 0023788471 scopus 로고
    • The short-term effect of an immunosuppressive treatment on CSF myelin basic protein in chronic progressive multiple sclerosis
    • Lamers KJ, Uitdehaag BM, Hommes OR, et al. The short-term effect of an immunosuppressive treatment on CSF myelin basic protein in chronic progressive multiple sclerosis. J Neurol Neurosurg Psychiatry. 1988 ; 51: 1334-1337
    • (1988) J Neurol Neurosurg Psychiatry , vol.51 , pp. 1334-1337
    • Lamers, K.J.1    Uitdehaag, B.M.2    Hommes, O.R.3
  • 18
    • 0037334950 scopus 로고    scopus 로고
    • Nitric oxide metabolite determinations reveal continuous inflammation in multiple sclerosis
    • Danilov AI, Andersson M, Bavand N, et al. Nitric oxide metabolite determinations reveal continuous inflammation in multiple sclerosis. J Neuroimmunol. 2003 ; 136: 112-118
    • (2003) J Neuroimmunol , vol.136 , pp. 112-118
    • Danilov, A.I.1    Andersson, M.2    Bavand, N.3
  • 19
    • 7044253039 scopus 로고    scopus 로고
    • CSF nitric oxide metabolites are associated with activity and progression of multiple sclerosis
    • Rejdak K, Eikelenboom MJ, Petzold A, et al. CSF nitric oxide metabolites are associated with activity and progression of multiple sclerosis. Neurology. 2004 ; 63: 1439-1445
    • (2004) Neurology , vol.63 , pp. 1439-1445
    • Rejdak, K.1    Eikelenboom, M.J.2    Petzold, A.3
  • 20
    • 82955198543 scopus 로고    scopus 로고
    • A phase III study evaluating the efficacy and safety of MBP8298 in secondary progressive MS
    • Freedman MS, Bar-Or A, Oger J, et al. A phase III study evaluating the efficacy and safety of MBP8298 in secondary progressive MS. Neurology. 2011 ; 77: 1551-1560
    • (2011) Neurology , vol.77 , pp. 1551-1560
    • Freedman, M.S.1    Bar-Or, A.2    Oger, J.3
  • 21
    • 0034955141 scopus 로고    scopus 로고
    • Recommended diagnostic criteria for multiple sclerosis: Guidelines from the International Panel on the diagnosis of multiple sclerosis
    • McDonald WI, Compston A, Edan G, et al. Recommended diagnostic criteria for multiple sclerosis: Guidelines from the International Panel on the diagnosis of multiple sclerosis. Ann Neurol. 2001 ; 50: 121-127
    • (2001) Ann Neurol , vol.50 , pp. 121-127
    • McDonald, W.I.1    Compston, A.2    Edan, G.3
  • 22
    • 0035941106 scopus 로고    scopus 로고
    • The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease
    • Chabas D, Baranzini SE, Mitchell D, et al. The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease. Science. 2001 ; 294: 1731-1735
    • (2001) Science , vol.294 , pp. 1731-1735
    • Chabas, D.1    Baranzini, S.E.2    Mitchell, D.3
  • 23
    • 0036105484 scopus 로고    scopus 로고
    • Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis
    • Lock C, Hermans G, Pedotti R, et al. Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis. Nat Med. 2002 ; 8: 500-508
    • (2002) Nat Med , vol.8 , pp. 500-508
    • Lock, C.1    Hermans, G.2    Pedotti, R.3
  • 24
    • 33846998653 scopus 로고    scopus 로고
    • Osteopontin-induced relapse and progression of autoimmune brain disease through enhanced survival of activated T cells
    • Hur EM, Youssef S, Haws ME, et al. Osteopontin-induced relapse and progression of autoimmune brain disease through enhanced survival of activated T cells. Nat Immunol. 2007 ; 8: 74-83
    • (2007) Nat Immunol , vol.8 , pp. 74-83
    • Hur, E.M.1    Youssef, S.2    Haws, M.E.3
  • 25
    • 43549094992 scopus 로고    scopus 로고
    • Increased osteopontin levels in the cerebrospinal fluid of patients with multiple sclerosis
    • Braitch M, Nunan R, Niepel G, et al. Increased osteopontin levels in the cerebrospinal fluid of patients with multiple sclerosis. Arch Neurol. 2008 ; 65: 633-635
    • (2008) Arch Neurol , vol.65 , pp. 633-635
    • Braitch, M.1    Nunan, R.2    Niepel, G.3
  • 26
    • 62849098757 scopus 로고    scopus 로고
    • The effects of natalizumab on inflammatory mediators in multiple sclerosis: Prospects for treatment-sensitive biomarkers
    • Khademi M, Bornsen L, Rafatnia F, et al. The effects of natalizumab on inflammatory mediators in multiple sclerosis: Prospects for treatment-sensitive biomarkers. Eur J Neurol. 2009 ; 16: 528-536
    • (2009) Eur J Neurol , vol.16 , pp. 528-536
    • Khademi, M.1    Bornsen, L.2    Rafatnia, F.3
  • 27
    • 30344446249 scopus 로고    scopus 로고
    • Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitment
    • Krumbholz M, Theil D, Cepok S, et al. Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitment. Brain. 2006 ; 129 (Pt 1). 200-211
    • (2006) Brain , vol.129 , Issue.PART 1 , pp. 200-211
    • Krumbholz, M.1    Theil, D.2    Cepok, S.3
  • 28
    • 2442708947 scopus 로고    scopus 로고
    • Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis
    • Serafini B, Rosicarelli B, Magliozzi R, et al. Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis. Brain Pathol. 2004 ; 14: 164-174
    • (2004) Brain Pathol , vol.14 , pp. 164-174
    • Serafini, B.1    Rosicarelli, B.2    Magliozzi, R.3
  • 29
    • 58149402415 scopus 로고    scopus 로고
    • Perivascular spaces and the two steps to neuroinflammation
    • Owens T, Bechmann I, Engelhardt B.. Perivascular spaces and the two steps to neuroinflammation. J Neuropathol Exp Neurol. 2008 ; 67: 1113-1121
    • (2008) J Neuropathol Exp Neurol , vol.67 , pp. 1113-1121
    • Owens, T.1    Bechmann, I.2    Engelhardt, B.3
  • 30
    • 0031798063 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 (gelatinase B) is selectively elevated in CSF during relapses and stable phases of multiple sclerosis
    • Leppert D, Ford J, Stabler G, et al. Matrix metalloproteinase-9 (gelatinase B) is selectively elevated in CSF during relapses and stable phases of multiple sclerosis. Brain. 1998 ; 121 (Pt 12). 2327-2334
    • (1998) Brain , vol.121 , Issue.PART 12 , pp. 2327-2334
    • Leppert, D.1    Ford, J.2    Stabler, G.3
  • 31
    • 20044394594 scopus 로고    scopus 로고
    • Up-regulation of osteopontin and alphaBeta-crystallin in the normal-appearing white matter of multiple sclerosis: An immunohistochemical study utilizing tissue microarrays
    • Sinclair C, Mirakhur M, Kirk J, et al. Up-regulation of osteopontin and alphaBeta-crystallin in the normal-appearing white matter of multiple sclerosis: An immunohistochemical study utilizing tissue microarrays. Neuropathol Appl Neurobiol. 2005 ; 31: 292-303
    • (2005) Neuropathol Appl Neurobiol , vol.31 , pp. 292-303
    • Sinclair, C.1    Mirakhur, M.2    Kirk, J.3
  • 32
    • 0034842248 scopus 로고    scopus 로고
    • The expression profile of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in lesions and normal appearing white matter of multiple sclerosis
    • Lindberg RL, De Groot CJ, Montagne L, et al. The expression profile of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in lesions and normal appearing white matter of multiple sclerosis. Brain. 2001 ; 124 (Pt 9). 1743-1753
    • (2001) Brain , vol.124 , Issue.PART 9 , pp. 1743-1753
    • Lindberg, R.L.1    De Groot, C.J.2    Montagne, L.3
  • 33
    • 0032408994 scopus 로고    scopus 로고
    • Cerebrospinal fluid measures of disease activity in patients with multiple sclerosis
    • Sellebjerg F, Christiansen M, Nielsen PM, et al. Cerebrospinal fluid measures of disease activity in patients with multiple sclerosis. Mult Scler. 1998 ; 4: 475-479
    • (1998) Mult Scler , vol.4 , pp. 475-479
    • Sellebjerg, F.1    Christiansen, M.2    Nielsen, P.M.3
  • 34
    • 0034465872 scopus 로고    scopus 로고
    • Immunological effects of oral high-dose methylprednisolone in acute optic neuritis and multiple sclerosis
    • Sellebjerg F, Christiansen M, Jensen J, et al. Immunological effects of oral high-dose methylprednisolone in acute optic neuritis and multiple sclerosis. Eur J Neurol. 2000 ; 7: 281-289
    • (2000) Eur J Neurol , vol.7 , pp. 281-289
    • Sellebjerg, F.1    Christiansen, M.2    Jensen, J.3
  • 35
    • 0037330434 scopus 로고    scopus 로고
    • Gadolinium-enhanced magnetic resonance imaging predicts response to methylprednisolone in multiple sclerosis
    • Sellebjerg F, Jensen CV, Larsson HB, et al. Gadolinium-enhanced magnetic resonance imaging predicts response to methylprednisolone in multiple sclerosis. Mult Scler. 2003 ; 9: 102-107
    • (2003) Mult Scler , vol.9 , pp. 102-107
    • Sellebjerg, F.1    Jensen, C.V.2    Larsson, H.B.3
  • 36
    • 79551478161 scopus 로고    scopus 로고
    • Axonal damage in relapsing multiple sclerosis is markedly reduced by natalizumab
    • Gunnarsson M, Malmestrom C, Axelsson M, et al. Axonal damage in relapsing multiple sclerosis is markedly reduced by natalizumab. Ann Neurol. 2011 ; 69: 83-89
    • (2011) Ann Neurol , vol.69 , pp. 83-89
    • Gunnarsson, M.1    Malmestrom, C.2    Axelsson, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.