메뉴 건너뛰기




Volumn 11, Issue 8, 2014, Pages 847-854

A method to recapitulate early embryonic spatial patterning in human embryonic stem cells

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN; BETA CATENIN; BONE MORPHOGENETIC PROTEIN 4; EPITHELIAL CELL ADHESION MOLECULE; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN NODAL; SMAD1 PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR BRA; TRANSCRIPTION FACTOR CDX2; TRANSCRIPTION FACTOR EOMES; TRANSCRIPTION FACTOR GATA 6; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR SOX17; TRANSCRIPTION FACTOR SOX2; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

EID: 84905258655     PISSN: 15487091     EISSN: 15487105     Source Type: Journal    
DOI: 10.1038/nMeth.3016     Document Type: Article
Times cited : (638)

References (41)
  • 1
    • 58849097959 scopus 로고    scopus 로고
    • Making a commitment: Cell lineage allocation and axis patterning in the early mouse embryo
    • Arnold, S.J. & Robertson, E.J. Making a commitment: cell lineage allocation and axis patterning in the early mouse embryo. Nat. Rev. Mol. Cell Biol. 10, 91-103 (2009).
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , pp. 91-103
    • Arnold, S.J.1    Robertson, E.J.2
  • 2
    • 28644448149 scopus 로고    scopus 로고
    • Effcient differentiation of human embryonic stem cells to defnitive endoderm
    • D'Amour, K.A. et al. Effcient differentiation of human embryonic stem cells to defnitive endoderm. Nat. Biotechnol. 23, 1534-1541 (2005).
    • (2005) Nat. Biotechnol. , vol.23 , pp. 1534-1541
    • D'Amour, K.A.1
  • 3
    • 62149125434 scopus 로고    scopus 로고
    • Highly effcient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling
    • Chambers, S.M. et al. Highly effcient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nat. Biotechnol. 27, 275-280 (2009).
    • (2009) Nat. Biotechnol. , vol.27 , pp. 275-280
    • Chambers, S.M.1
  • 4
    • 79551597211 scopus 로고    scopus 로고
    • Stage-specifc optimization of Activin/Nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines
    • Kattman, S.J. et al. Stage-specifc optimization of Activin/Nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines. Cell Stem Cell 8, 228-240 (2011).
    • (2011) Cell Stem Cell , vol.8 , pp. 228-240
    • Kattman, S.J.1
  • 5
    • 84871535695 scopus 로고    scopus 로고
    • SMAD7 directly converts human embryonic stem cells to telencephalic fate by a default mechanism
    • Ozair, M.Z., Noggle, S., Warmfash, A., Krzyspiak, J.E. & Brivanlou, A.H. SMAD7 directly converts human embryonic stem cells to telencephalic fate by a default mechanism. Stem Cells 31, 35-47 (2013).
    • (2013) Stem Cells , vol.31 , pp. 35-47
    • Ozair, M.Z.1    Noggle, S.2    Warmfash, A.3    Krzyspiak, J.E.4    Brivanlou, A.H.5
  • 6
    • 33747842468 scopus 로고    scopus 로고
    • The nodal precursor acting via activin receptors induces mesoderm by maintaining a source of its convertases and BMP4
    • Ben-Haim, N. et al. The nodal precursor acting via activin receptors induces mesoderm by maintaining a source of its convertases and BMP4. Dev. Cell 11, 313-323 (2006).
    • (2006) Dev. Cell , vol.11 , pp. 313-323
    • Ben-Haim, N.1
  • 7
    • 54949102409 scopus 로고    scopus 로고
    • Wnt signaling mediates self-organization and axis formation in embryoid bodies
    • ten Berge, D. et al. Wnt signaling mediates self-organization and axis formation in embryoid bodies. Cell Stem Cell 3, 508-518 (2008).
    • (2008) Cell Stem Cell , vol.3 , pp. 508-518
    • Ten Berge, D.1
  • 8
    • 84862000566 scopus 로고    scopus 로고
    • Isolation of primitive endoderm, mesoderm, vascular endothelial and trophoblast progenitors from human pluripotent stem cells
    • Drukker, M. et al. Isolation of primitive endoderm, mesoderm, vascular endothelial and trophoblast progenitors from human pluripotent stem cells. Nat. Biotechnol. 30, 531-542 (2012).
    • (2012) Nat. Biotechnol. , vol.30 , pp. 531-542
    • Drukker, M.1
  • 9
    • 84867028809 scopus 로고    scopus 로고
    • Endogenous Wnt signalling in human embryonic stem cells generates an equilibrium of distinct lineage-specifed progenitors
    • Blauwkamp, T.A., Nigam, S., Ardehali, R., Weissman, I.L. & Nusse, R. Endogenous Wnt signalling in human embryonic stem cells generates an equilibrium of distinct lineage-specifed progenitors. Nat. Commun. 3, 1070 (2012).
    • (2012) Nat. Commun. , vol.3 , pp. 1070
    • Blauwkamp, T.A.1    Nigam, S.2    Ardehali, R.3    Weissman, I.L.4    Nusse, R.5
  • 10
    • 36249022693 scopus 로고    scopus 로고
    • Niche-mediated control of human embryonic stem cell self-renewal and differentiation
    • Peerani, R. et al. Niche-mediated control of human embryonic stem cell self-renewal and differentiation. EMBO J. 26, 4744-4755 (2007).
    • (2007) EMBO J. , vol.26 , pp. 4744-4755
    • Peerani, R.1
  • 11
    • 55049120510 scopus 로고    scopus 로고
    • Control of human embryonic stem cell colony and aggregate size heterogeneity infuences differentiation trajectories
    • Bauwens, C.L. et al. Control of human embryonic stem cell colony and aggregate size heterogeneity infuences differentiation trajectories. Stem Cells 26, 2300-2310 (2008).
    • (2008) Stem Cells , vol.26 , pp. 2300-2310
    • Bauwens, C.L.1
  • 12
    • 78650991303 scopus 로고    scopus 로고
    • Embryoid body culture of mouse embryonic stem cells using microwell and micropatterned chips
    • Sakai, Y., Yoshiura, Y. & Nakazawa, K. Embryoid body culture of mouse embryonic stem cells using microwell and micropatterned chips. J. Biosci. Bioeng. 111, 85-91 (2011).
    • (2011) J. Biosci. Bioeng. , vol.111 , pp. 85-91
    • Sakai, Y.1    Yoshiura, Y.2    Nakazawa, K.3
  • 13
    • 16244400050 scopus 로고    scopus 로고
    • TGFβ/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells
    • James, D., Levine, A.J., Besser, D. & Hemmati-Brivanlou, A. TGFβ/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells. Development 132, 1273-1282 (2005).
    • (2005) Development , vol.132 , pp. 1273-1282
    • James, D.1    Levine, A.J.2    Besser, D.3    Hemmati-Brivanlou, A.4
  • 14
    • 48149098004 scopus 로고    scopus 로고
    • NANOG is a direct target of TGFβ/activin-mediated SMAD signaling in human ESCs
    • Xu, R.-H. et al. NANOG is a direct target of TGFβ/activin-mediated SMAD signaling in human ESCs. Cell Stem Cell 3, 196-206 (2008).
    • (2008) Cell Stem Cell , vol.3 , pp. 196-206
    • Xu, R.-H.1
  • 15
    • 1242267927 scopus 로고    scopus 로고
    • Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specifc inhibitor
    • Sato, N., Meijer, L., Skaltsounis, L., Greengard, P. & Brivanlou, A.H. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specifc inhibitor. Nat. Med. 10, 55-63 (2004).
    • (2004) Nat. Med. , vol.10 , pp. 55-63
    • Sato, N.1    Meijer, L.2    Skaltsounis, L.3    Greengard, P.4    Brivanlou, A.H.5
  • 16
    • 79952161362 scopus 로고    scopus 로고
    • FGF2 sustains NANOG and switches the outcome of BMP4-induced human embryonic stem cell differentiation
    • Yu, P., Pan, G., Yu, J. & Thomson, J.A. FGF2 sustains NANOG and switches the outcome of BMP4-induced human embryonic stem cell differentiation. Cell Stem Cell 8, 326-334 (2011).
    • (2011) Cell Stem Cell , vol.8 , pp. 326-334
    • Yu, P.1    Pan, G.2    Yu, J.3    Thomson, J.A.4
  • 17
    • 84875522268 scopus 로고    scopus 로고
    • Complete and unidirectional conversion of human embryonic stem cells to trophoblast by BMP4
    • Amita, M. et al. Complete and unidirectional conversion of human embryonic stem cells to trophoblast by BMP4. Proc. Natl. Acad. Sci. USA 110, E1212-E1221 (2013).
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110
    • Amita, M.1
  • 18
    • 84867800506 scopus 로고    scopus 로고
    • FGF inhibition directs BMP4-mediated differentiation of human embryonic stem cells to syncytiotrophoblast
    • Sudheer, S., Bhushan, R., Fauler, B., Lehrach, H. & Adjaye, J. FGF inhibition directs BMP4-mediated differentiation of human embryonic stem cells to syncytiotrophoblast. Stem Cells Dev. 21, 2987-3000 (2012).
    • (2012) Stem Cells Dev. , vol.21 , pp. 2987-3000
    • Sudheer, S.1    Bhushan, R.2    Fauler, B.3    Lehrach, H.4    Adjaye, J.5
  • 19
    • 84884246541 scopus 로고    scopus 로고
    • + cytotrophoblast stem cell state
    • + cytotrophoblast stem cell state. Development 140, 3965-3976 (2013).
    • (2013) Development , vol.140 , pp. 3965-3976
    • Li, Y.1
  • 20
    • 79961149681 scopus 로고    scopus 로고
    • BRACHYURY and CDX2 mediate BMP-induced differentiation of human and mouse pluripotent stem cells into embryonic and extraembryonic lineages
    • Bernardo, A.S. et al. BRACHYURY and CDX2 mediate BMP-induced differentiation of human and mouse pluripotent stem cells into embryonic and extraembryonic lineages. Cell Stem Cell 9, 144-155 (2011).
    • (2011) Cell Stem Cell , vol.9 , pp. 144-155
    • Bernardo, A.S.1
  • 21
    • 79953847687 scopus 로고    scopus 로고
    • A precarious balance: Pluripotency factors as lineage specifers
    • Loh, K.M. & Lim, B. A precarious balance: pluripotency factors as lineage specifers. Cell Stem Cell 8, 363-369 (2011).
    • (2011) Cell Stem Cell , vol.8 , pp. 363-369
    • Loh, K.M.1    Lim, B.2
  • 22
    • 79958263080 scopus 로고    scopus 로고
    • Pluripotency factors in embryonic stem cells regulate differentiation into germ layers
    • Thomson, M. et al. Pluripotency factors in embryonic stem cells regulate differentiation into germ layers. Cell 145, 875-889 (2011).
    • (2011) Cell , vol.145 , pp. 875-889
    • Thomson, M.1
  • 23
    • 79551592864 scopus 로고    scopus 로고
    • Pluripotency factors regulate defnitive endoderm specifcation through eomesodermin
    • Teo, A.K.K. et al. Pluripotency factors regulate defnitive endoderm specifcation through eomesodermin. Genes Dev. 25, 238-250 (2011).
    • (2011) Genes Dev. , vol.25 , pp. 238-250
    • Teo, A.K.K.1
  • 24
    • 84859539293 scopus 로고    scopus 로고
    • Distinct lineage specifcation roles for NANOG, OCT4, and SOX2 in human embryonic stem cells
    • Wang, Z., Oron, E., Nelson, B., Razis, S. & Ivanova, N. Distinct lineage specifcation roles for NANOG, OCT4, and SOX2 in human embryonic stem cells. Cell Stem Cell 10, 440-454 (2012).
    • (2012) Cell Stem Cell , vol.10 , pp. 440-454
    • Wang, Z.1    Oron, E.2    Nelson, B.3    Razis, S.4    Ivanova, N.5
  • 25
    • 84887150842 scopus 로고    scopus 로고
    • Location of transient ectodermal progenitor potential in mouse development
    • Li, L. et al. Location of transient ectodermal progenitor potential in mouse development. Development 140, 4533-4543 (2013).
    • (2013) Development , vol.140 , pp. 4533-4543
    • Li, L.1
  • 27
    • 84856221662 scopus 로고    scopus 로고
    • Mouse primitive streak forms in situ by initiation of epithelial to mesenchymal transition without migration of a cell population
    • Williams, M., Burdsal, C., Periasamy, A., Lewandoski, M. & Sutherland, A. Mouse primitive streak forms in situ by initiation of epithelial to mesenchymal transition without migration of a cell population. Dev. Dyn. 241, 270-283 (2012).
    • (2012) Dev. Dyn. , vol.241 , pp. 270-283
    • Williams, M.1    Burdsal, C.2    Periasamy, A.3    Lewandoski, M.4    Sutherland, A.5
  • 28
    • 75349094231 scopus 로고    scopus 로고
    • Characterization of epithelial cell adhesion molecule as a surface marker on undifferentiated human embryonic stem cells
    • Ng, V.Y., Ang, S.N., Chan, J.X. & Choo, A.B.H. Characterization of epithelial cell adhesion molecule as a surface marker on undifferentiated human embryonic stem cells. Stem Cells 28, 29-35 (2010).
    • (2010) Stem Cells , vol.28 , pp. 29-35
    • Ng, V.Y.1    Ang, S.N.2    Chan, J.X.3    Choo, A.B.H.4
  • 29
    • 0036085920 scopus 로고    scopus 로고
    • SB-431542 is a potent and specifc inhibitor of transforming growth factor-β superfamily type i activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7
    • Inman, G.J. et al. SB-431542 is a potent and specifc inhibitor of transforming growth factor-β superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7. Mol. Pharmacol. 62, 65-74 (2002).
    • (2002) Mol. Pharmacol. , vol.62 , pp. 65-74
    • Inman, G.J.1
  • 30
    • 0034628534 scopus 로고    scopus 로고
    • The organizer factors Chordin and Noggin are required for mouse forebrain development
    • Bachiller, D. et al. The organizer factors Chordin and Noggin are required for mouse forebrain development. Nature 403, 658-661 (2000).
    • (2000) Nature , vol.403 , pp. 658-661
    • Bachiller, D.1
  • 31
    • 18744404768 scopus 로고    scopus 로고
    • Nodal antagonists in the anterior visceral endoderm prevent the formation of multiple primitive streaks
    • Perea-Gomez, A. et al. Nodal antagonists in the anterior visceral endoderm prevent the formation of multiple primitive streaks. Dev. Cell 3, 745-756 (2002).
    • (2002) Dev. Cell , vol.3 , pp. 745-756
    • Perea-Gomez, A.1
  • 32
    • 0033756556 scopus 로고    scopus 로고
    • A fattened mouse embryo: Leveling the playing feld
    • Behringer, R.R., Wakamiya, M., Tsang, T.E. & Tam, P.P. A fattened mouse embryo: leveling the playing feld. Genesis 28, 23-30 (2000).
    • (2000) Genesis , vol.28 , pp. 23-30
    • Behringer, R.R.1    Wakamiya, M.2    Tsang, T.E.3    Tam, P.P.4
  • 34
    • 70350126572 scopus 로고    scopus 로고
    • Microwell-mediated control of embryoid body size regulates embryonic stem cell fate via differential expression of WNT5a and WNT11
    • Hwang, Y.-S. et al. Microwell-mediated control of embryoid body size regulates embryonic stem cell fate via differential expression of WNT5a and WNT11. Proc. Natl. Acad. Sci. USA 106, 16978-16983 (2009).
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 16978-16983
    • Hwang, Y.-S.1
  • 35
    • 84857735045 scopus 로고    scopus 로고
    • Predictive microfuidic control of regulatory ligand trajectories in individual pluripotent cells
    • Moledina, F. et al. Predictive microfuidic control of regulatory ligand trajectories in individual pluripotent cells. Proc. Natl. Acad. Sci. USA 109, 3264-3269 (2012).
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 3264-3269
    • Moledina, F.1
  • 36
    • 79953749322 scopus 로고    scopus 로고
    • Self-organizing optic-cup morphogenesis in three-dimensional culture
    • Eiraku, M. et al. Self-organizing optic-cup morphogenesis in three-dimensional culture. Nature 472, 51-56 (2011).
    • (2011) Nature , vol.472 , pp. 51-56
    • Eiraku, M.1
  • 37
    • 84884414984 scopus 로고    scopus 로고
    • Cerebral organoids model human brain development and microcephaly
    • Lancaster, M.A. et al. Cerebral organoids model human brain development and microcephaly. Nature 501, 373-379 (2013).
    • (2013) Nature , vol.501 , pp. 373-379
    • Lancaster, M.A.1
  • 38
    • 67349123408 scopus 로고    scopus 로고
    • Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
    • Sato, T. et al. Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature 459, 262-265 (2009).
    • (2009) Nature , vol.459 , pp. 262-265
    • Sato, T.1
  • 39
    • 84878760040 scopus 로고    scopus 로고
    • Growing self-organizing mini-guts from a single intestinal stem cell: Mechanism and applications
    • Sato, T. & Clevers, H. Growing self-organizing mini-guts from a single intestinal stem cell: mechanism and applications. Science 340, 1190-1194 (2013).
    • (2013) Science , vol.340 , pp. 1190-1194
    • Sato, T.1    Clevers, H.2
  • 40
    • 79551686425 scopus 로고    scopus 로고
    • Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro
    • Spence, J.R. et al. Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro. Nature 470, 105-109 (2011).
    • (2011) Nature , vol.470 , pp. 105-109
    • Spence, J.R.1
  • 41
    • 84863977346 scopus 로고    scopus 로고
    • Dynamics of TGF-β signaling reveal adaptive and pulsatile behaviors refected in the nuclear localization of transcription factor SMAD4
    • Warmfash, A. et al. Dynamics of TGF-β signaling reveal adaptive and pulsatile behaviors refected in the nuclear localization of transcription factor SMAD4. Proc. Natl. Acad. Sci. USA 109, E1947-E1956 (2012).
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109
    • Warmfash, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.