BMP4-directed trophoblast differentiation of human embryonic stem cells is mediated through a ΔNp63+ cytotrophoblast stem cell state

Development (Cambridge)

Volumn 140, Issue 19, 2013, Pages 3965-3976

  Li, Yingchun ^a   Moretto Zita, Matteo ^a   Soncin, Francesca ^a   Wakeland, Anna ^a   Wolfe, Lynlee ^a   Leon Garcia, Sandra ^a   Pandian, Raj ^b   Pizzo, Donald ^a   Cui, Li ^a   Nazor, Kristopher ^c   Loring, Jeanne F ^c   Crum, Christopher P ^d   Laurent, Louise C ^a   Parast, Mana M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b QUEST DIAGNOSTICS NICHOLS INSTITUTE   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Np63; BMP4; Human embryonic stem cells; Placenta; Trophoblast

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; CYCLIN B1; KRUPPEL LIKE FACTOR 4; PROTEIN P53; PROTEIN P63; SHORT HAIRPIN RNA;

ARTICLE; CELL DIFFERENTIATION; CHORION VILLUS; CYTOTROPHOBLAST; DOWN REGULATION; EMBRYO; EMBRYONIC STEM CELL; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNCYTIOTROPHOBLAST; TROPHOBLAST;

ΔNP63; BMP4; HUMAN EMBRYONIC STEM CELLS; PLACENTA; TROPHOBLAST;

BONE MORPHOGENETIC PROTEIN 4; CELL DIFFERENTIATION; CELLS, CULTURED; EMBRYONIC STEM CELLS; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GESTATIONAL AGE; HUMANS; PLACENTA; PREGNANCY; REAL-TIME POLYMERASE CHAIN REACTION; TROPHOBLASTS;

EID: 84884246541     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.092155     Document Type: Article

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