A unique DNA entry gate serves for regulated loading of the eukaryotic replicative helicase MCM2-7 onto DNA

Genes and Development

Volumn 28, Issue 15, 2014, Pages 1653-1666

  Samel, Stefan A ^a   Fernández Cid, Alejandra ^a   Sun, Jingchuan ^b   Riera, Alberto ^a   Tognetti, Silvia ^a   Carmen Herrera, M ^a   Li, Huilin ^b,c   Speck, Christian ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b BROOKHAVEN NATIONAL LABORATORY   (United States)

^c STONY BROOK UNIVERSITY   (United States)

Author keywords

Cancer; DNA licensing; DNA replication; Genomic stability; pre RC; Replicative helicase

Indexed keywords

ADENOSINE TRIPHOSPHATASE; DNA; HELICASE; MINICHROMOSOME MAINTENANCE PROTEIN 2; MINICHROMOSOME MAINTENANCE PROTEIN 3; MINICHROMOSOME MAINTENANCE PROTEIN 4; MINICHROMOSOME MAINTENANCE PROTEIN 5; MINICHROMOSOME MAINTENANCE PROTEIN 6; MINICHROMOSOME MAINTENANCE PROTEIN 7;

ARTICLE; CELL CYCLE PROGRESSION; CHROMATIN; COMPLEX FORMATION; CONTROLLED STUDY; DNA PROTEIN COMPLEX; DNA REPLICATION; GENE INSERTION; GENOMIC INSTABILITY; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; SACCHAROMYCES CEREVISIAE;

CANCER; DNA LICENSING; DNA REPLICATION; GENOMIC STABILITY; PRE-RC; REPLICATIVE HELICASE;

ADENOSINE TRIPHOSPHATE; CELL CYCLE; CHROMOSOMES, FUNGAL; DNA, FUNGAL; ENZYME ACTIVATION; HYDROLYSIS; MINICHROMOSOME MAINTENANCE PROTEINS; MULTIPROTEIN COMPLEXES; PROTEIN SUBUNITS; REPLICATION ORIGIN; SACCHAROMYCES CEREVISIAE;

EID: 84905255551     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.242404.114     Document Type: Article

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