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Volumn 38, Issue 18, 2010, Pages 6078-6088

The Saccharomyces cerevisiae Mcm6/2 and Mcm5/3 ATPase active sites contribute to the function of the putative Mcm2-7 'gate'

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ARGININE; MINICHROMOSOME MAINTENANCE PROTEIN 2; MINICHROMOSOME MAINTENANCE PROTEIN 3; MINICHROMOSOME MAINTENANCE PROTEIN 4; MINICHROMOSOME MAINTENANCE PROTEIN 5; MINICHROMOSOME MAINTENANCE PROTEIN 6; MINICHROMOSOME MAINTENANCE PROTEIN 7; CDC46 PROTEIN, S CEREVISIAE; CDC47 PROTEIN, S CEREVISIAE; CELL CYCLE PROTEIN; CIRCULAR DNA; DNA; DNA BINDING PROTEIN; HELICASE; MCM2 PROTEIN, S CEREVISIAE; MCM3 PROTEIN, S CEREVISIAE; MCM6 PROTEIN, S CEREVISIAE; NONHISTONE PROTEIN; NUCLEAR PROTEIN; PROTEIN SUBUNIT; SACCHAROMYCES CEREVISIAE PROTEIN; SINGLE STRANDED DNA;

EID: 78049431126     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkq422     Document Type: Article
Times cited : (45)

References (29)
  • 1
    • 71449107031 scopus 로고    scopus 로고
    • The Mcm complex: unwinding the mechanism of a replicative helicase
    • Bochman,M. and Schwacha,A. (2009) The Mcm complex: unwinding the mechanism of a replicative helicase. Microbiol. Mol. Biol. Rev., 73, 652-683.
    • (2009) Microbiol. Mol. Biol. Rev. , vol.73 , pp. 652-683
    • Bochman, M.1    Schwacha, A.2
  • 2
    • 33745041480 scopus 로고    scopus 로고
    • Evolutionary relationships and structural mechanisms of AAA + proteins
    • Erzberger,J.P. and Berger,J.M. (2006) Evolutionary relationships and structural mechanisms of AAA + proteins. Annu. Rev. Biophys. Biomol. Struct., 35, 93-114.
    • (2006) Annu. Rev. Biophys. Biomol. Struct. , vol.35 , pp. 93-114
    • Erzberger, J.P.1    Berger, J.M.2
  • 3
    • 1642325936 scopus 로고    scopus 로고
    • Evolutionary history and higher order classification of AAA + ATPases
    • Iyer,L.M., Leipe,D.D., Koonin,E.V. and Aravind,L. (2004) Evolutionary history and higher order classification of AAA + ATPases. J. Struct. Biol., 146, 11-31.
    • (2004) J. Struct. Biol. , vol.146 , pp. 11-31
    • Iyer, L.M.1    Leipe, D.D.2    Koonin, E.V.3    Aravind, L.4
  • 4
    • 0027267908 scopus 로고
    • A common set of conserved motifs in a vast variety of putative nucleic acid-dependent ATPases including MCM proteins involved in the initiation of eukaryotic DNA replication
    • Koonin,E.V. (1993) A common set of conserved motifs in a vast variety of putative nucleic acid-dependent ATPases including MCM proteins involved in the initiation of eukaryotic DNA replication. Nucleic Acids Res., 21, 2541-2547.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 2541-2547
    • Koonin, E.V.1
  • 5
    • 36349008252 scopus 로고    scopus 로고
    • Differences in the single-stranded DNA binding activities of MCM2-7 and MCM467: MCM2 and MCM5 define a slow ATP-dependent step
    • Bochman,M.L. and Schwacha,A. (2007) Differences in the single-stranded DNA binding activities of MCM2-7 and MCM467: MCM2 and MCM5 define a slow ATP-dependent step. J. Biol. Chem., 282, 33795-33804.
    • (2007) J. Biol. Chem. , vol.282 , pp. 33795-33804
    • Bochman, M.L.1    Schwacha, A.2
  • 6
    • 0348133607 scopus 로고    scopus 로고
    • Hexameric ring structure of the full-length archaeal MCM protein complex
    • Pape,T., Meka,H., Chen,S., Vicentini,G., van Heel,M. and Onesti,S. (2003) Hexameric ring structure of the full-length archaeal MCM protein complex. EMBO Rep., 4, 1079-1083.
    • (2003) EMBO Rep. , vol.4 , pp. 1079-1083
    • Pape, T.1    Meka, H.2    Chen, S.3    Vicentini, G.4    van Heel, M.5    Onesti, S.6
  • 7
    • 0033786801 scopus 로고    scopus 로고
    • Structure and function of hexameric helicases
    • Patel,S.S. and Picha,K.M. (2000) Structure and function of hexameric helicases. Annu. Rev. Biochem., 69, 651-697.
    • (2000) Annu. Rev. Biochem. , vol.69 , pp. 651-697
    • Patel, S.S.1    Picha, K.M.2
  • 8
    • 1542405310 scopus 로고    scopus 로고
    • Eukaryotic MCM proteins: beyond replication initiation
    • Forsburg,S.L. (2004) Eukaryotic MCM proteins: beyond replication initiation. Microbiol. Mol. Biol. Rev., 68, 109-131.
    • (2004) Microbiol. Mol. Biol. Rev. , vol.68 , pp. 109-131
    • Forsburg, S.L.1
  • 9
    • 64549101067 scopus 로고    scopus 로고
    • Ancient diversification of eukaryotic MCM DNA replication proteins
    • Liu,Y., Richards,T.A. and Aves,S.J. (2009) Ancient diversification of eukaryotic MCM DNA replication proteins. BMC Evol. Biol., 9, 60.
    • (2009) BMC Evol. Biol. , vol.9 , pp. 60
    • Liu, Y.1    Richards, T.A.2    Aves, S.J.3
  • 11
    • 22744445013 scopus 로고    scopus 로고
    • Pumps, paradoxes and ploughshares: mechanism of the MCM2-7 DNA helicase
    • Takahashi,T.S., Wigley,D.B. and Walter,J.C. (2005) Pumps, paradoxes and ploughshares: mechanism of the MCM2-7 DNA helicase. Trends Biochem. Sci., 30, 437-444.
    • (2005) Trends Biochem. Sci. , vol.30 , pp. 437-444
    • Takahashi, T.S.1    Wigley, D.B.2    Walter, J.C.3
  • 12
    • 52649096993 scopus 로고    scopus 로고
    • Subunit organization of Mcm2-7 and the unequal role of active sites in ATP hydrolysis and viability
    • Bochman,M.L., Bell,S.P. and Schwacha,A. (2008) Subunit organization of Mcm2-7 and the unequal role of active sites in ATP hydrolysis and viability. Mol. Cell. Biol., 28, 5865-5873.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 5865-5873
    • Bochman, M.L.1    Bell, S.P.2    Schwacha, A.3
  • 13
    • 0038475879 scopus 로고    scopus 로고
    • Reconstitution of the Mcm2-7p heterohexamer, subunit arrangement, and ATP site architecture
    • Davey,M.J., Indiani,C. and O'Donnell,M. (2003) Reconstitution of the Mcm2-7p heterohexamer, subunit arrangement, and ATP site architecture. J. Biol. Chem., 278, 4491-4499.
    • (2003) J. Biol. Chem. , vol.278 , pp. 4491-4499
    • Davey, M.J.1    Indiani, C.2    O'Donnell, M.3
  • 14
    • 47349114465 scopus 로고    scopus 로고
    • The Mcm2-7 complex has in vitro helicase activity
    • Bochman,M.L. and Schwacha,A. (2008) The Mcm2-7 complex has in vitro helicase activity. Mol. Cell, 31, 287-293.
    • (2008) Mol. Cell , vol.31 , pp. 287-293
    • Bochman, M.L.1    Schwacha, A.2
  • 15
    • 0035930346 scopus 로고    scopus 로고
    • Interactions between two catalytically distinct MCM subgroups are essential for coordinated ATP hydrolysis and DNA replication
    • Schwacha,A. and Bell,S.P. (2001) Interactions between two catalytically distinct MCM subgroups are essential for coordinated ATP hydrolysis and DNA replication. Mol. Cell, 8, 1093-1104.
    • (2001) Mol. Cell , vol.8 , pp. 1093-1104
    • Schwacha, A.1    Bell, S.P.2
  • 16
    • 67650683478 scopus 로고    scopus 로고
    • ATP binding and hydrolysis by Mcm2 regulate DNA binding by Mcm complexes
    • Stead,B.E., Sorbara,C.D., Brandl,C.J. and Davey,M.J. (2009) ATP binding and hydrolysis by Mcm2 regulate DNA binding by Mcm complexes. J. Mol. Biol., 391, 301-313.
    • (2009) J. Mol. Biol. , vol.391 , pp. 301-313
    • Stead, B.E.1    Sorbara, C.D.2    Brandl, C.J.3    Davey, M.J.4
  • 17
    • 57649171240 scopus 로고    scopus 로고
    • Mcm subunits can assemble into two different active unwinding complexes
    • Kanter,D.M., Bruck,I. and Kaplan,D.L. (2008) Mcm subunits can assemble into two different active unwinding complexes. J. Biol. Chem., 283, 31172-31182.
    • (2008) J. Biol. Chem. , vol.283 , pp. 31172-31182
    • Kanter, D.M.1    Bruck, I.2    Kaplan, D.L.3
  • 18
    • 0030859463 scopus 로고    scopus 로고
    • A DNA helicase activity is associated with an MCM4, -6, and -7 protein complex
    • Ishimi,Y. (1997) A DNA helicase activity is associated with an MCM4, -6, and -7 protein complex. J. Biol. Chem., 272, 24508-24513.
    • (1997) J. Biol. Chem. , vol.272 , pp. 24508-24513
    • Ishimi, Y.1
  • 20
    • 0014945567 scopus 로고
    • The lac repressor-operator interaction. 3. Kinetic studies
    • Riggs,A.D., Bourgeois,S. and Cohn,M. (1970) The lac repressor-operator interaction. 3. Kinetic studies. J. Mol. Biol., 53, 401-417.
    • (1970) J. Mol. Biol. , vol.53 , pp. 401-417
    • Riggs, A.D.1    Bourgeois, S.2    Cohn, M.3
  • 21
    • 0019867850 scopus 로고
    • Diffusion-driven mechanisms of protein translocation on nucleic acids. 3. The Escherichia coli lac repressor-operator interaction: kinetic measurements and conclusions
    • Winter,R.B., Berg,O.G. and von Hippel,P.H. (1981) Diffusion-driven mechanisms of protein translocation on nucleic acids. 3. The Escherichia coli lac repressor-operator interaction: kinetic measurements and conclusions. Biochemistry, 20, 6961-6977.
    • (1981) Biochemistry , vol.20 , pp. 6961-6977
    • Winter, R.B.1    Berg, O.G.2    von Hippel, P.H.3
  • 22
    • 74749095240 scopus 로고    scopus 로고
    • Activation of the MCM2-7 helicase by association with Cdc45 and GINS proteins
    • Ilves,I., Petojevic,T., Pesavento,J.J. and Botchan,M.R. (2010) Activation of the MCM2-7 helicase by association with Cdc45 and GINS proteins. Mol. Cell, 37, 247-258.
    • (2010) Mol. Cell , vol.37 , pp. 247-258
    • Ilves, I.1    Petojevic, T.2    Pesavento, J.J.3    Botchan, M.R.4
  • 23
    • 0026501124 scopus 로고
    • Simian virus 40 T-antigen DNA helicase is a hexamer which forms a binary complex during bidirectional unwinding from the viral origin of DNA replication
    • Wessel,R., Schweizer,J. and Stahl,H. (1992) Simian virus 40 T-antigen DNA helicase is a hexamer which forms a binary complex during bidirectional unwinding from the viral origin of DNA replication. J. Virol., 66, 804-815.
    • (1992) J. Virol. , vol.66 , pp. 804-815
    • Wessel, R.1    Schweizer, J.2    Stahl, H.3
  • 24
    • 4444226952 scopus 로고    scopus 로고
    • Mechanisms of conformational change for a replicative hexameric helicase of SV40 large tumor antigen
    • Gai,D., Zhao,R., Li,D., Finkielstein,C.V. and Chen,X.S. (2004) Mechanisms of conformational change for a replicative hexameric helicase of SV40 large tumor antigen. Cell, 119, 47-60.
    • (2004) Cell , vol.119 , pp. 47-60
    • Gai, D.1    Zhao, R.2    Li, D.3    Finkielstein, C.V.4    Chen, X.S.5
  • 25
    • 35348971984 scopus 로고    scopus 로고
    • ATPase site architecture and helicase mechanism of an archaeal MCM
    • Moreau,M.J., McGeoch,A.T., Lowe,A.R., Itzhaki,L.S. and Bell,S.D. (2007) ATPase site architecture and helicase mechanism of an archaeal MCM. Mol. Cell, 28, 304-314.
    • (2007) Mol. Cell , vol.28 , pp. 304-314
    • Moreau, M.J.1    McGeoch, A.T.2    Lowe, A.R.3    Itzhaki, L.S.4    Bell, S.D.5
  • 27
    • 70350751416 scopus 로고    scopus 로고
    • Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing
    • Remus,D., Beuron,F., Tolun,G., Griffith,J.D., Morris,E.P. and Diffley,J.F. (2009) Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing. Cell, 139, 719-730.
    • (2009) Cell , vol.139 , pp. 719-730
    • Remus, D.1    Beuron, F.2    Tolun, G.3    Griffith, J.D.4    Morris, E.P.5    Diffley, J.F.6
  • 28
    • 23944507608 scopus 로고    scopus 로고
    • Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork
    • Calzada,A., Hodgson,B., Kanemaki,M., Bueno,A. and Labib,K. (2005) Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork. Genes Dev., 19, 1905-1919.
    • (2005) Genes Dev. , vol.19 , pp. 1905-1919
    • Calzada, A.1    Hodgson, B.2    Kanemaki, M.3    Bueno, A.4    Labib, K.5
  • 29
    • 33745925880 scopus 로고    scopus 로고
    • Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase
    • Moyer,S.E., Lewis,P.W. and Botchan,M.R. (2006) Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase. Proc. Natl Acad. Sci. USA, 103, 10236-10241.
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 10236-10241
    • Moyer, S.E.1    Lewis, P.W.2    Botchan, M.R.3


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