메뉴 건너뛰기




Volumn 42, Issue 4, 2014, Pages 2257-2269

The ORC/Cdc6/MCM2-7 complex facilitates MCM2-7 dimerization during prereplicative complex formation

Author keywords

[No Author keywords available]

Indexed keywords

HELICASE; MINICHROMOSOME MAINTENANCE PROTEIN 2 7 HELICASE; MULTIPROTEIN COMPLEX; ORIGIN RECOGNITION COMPLEX CELL CYCLE PROTEIN 6 MINICHROMOSOME MAINTENANCE PROTEIN 2 7 COMPLEX; PREREPLICATIVE COMPLEX; REPLICATION LICENSING FACTOR CDT1; UNCLASSIFIED DRUG;

EID: 84895788981     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkt1148     Document Type: Article
Times cited : (30)

References (31)
  • 1
    • 40549108563 scopus 로고    scopus 로고
    • Cell cycle regulation of DNA replication
    • Sclafani, R.A. and Holzen, T.M. (2007) Cell cycle regulation of DNA replication. Annu. Rev. Genet., 41, 237-280.
    • (2007) Annu. Rev. Genet. , vol.41 , pp. 237-280
    • Sclafani, R.A.1    Holzen, T.M.2
  • 2
    • 70549085855 scopus 로고    scopus 로고
    • Eukaryotic DNA replication control: Lock and load then fire
    • Remus, D. and Diffley, J.F. (2009) Eukaryotic DNA replication control: lock and load, then fire. Curr. Opin. Cell Biol., 21, 771-777.
    • (2009) Curr. Opin. Cell Biol. , vol.21 , pp. 771-777
    • Remus, D.1    Diffley, J.F.2
  • 3
    • 73949091058 scopus 로고    scopus 로고
    • A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication
    • Evrin, C., Clarke, P., Zech, J., Lurz, R., Sun, J., Uhle, S., Li, H., Stillman, B. and Speck, C. (2009) A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication. Proc. Natl Acad. Sci. USA, 106, 20240-20245.
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 20240-20245
    • Evrin, C.1    Clarke, P.2    Zech, J.3    Lurz, R.4    Sun, J.5    Uhle, S.6    Li, H.7    Stillman, B.8    Speck, C.9
  • 4
    • 70350751416 scopus 로고    scopus 로고
    • Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing
    • Remus, D., Beuron, F., Tolun, G., Griffith, J.D., Morris, E.P. and Diffley, J.F. (2009) Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing. Cell, 139, 719-730.
    • (2009) Cell , vol.139 , pp. 719-730
    • Remus, D.1    Beuron, F.2    Tolun, G.3    Griffith, J.D.4    Morris, E.P.5    Diffley, J.F.6
  • 5
    • 79953220813 scopus 로고    scopus 로고
    • MCM2-7 form double hexamers at licensed origins in Xenopus egg extract
    • Gambus, A., Khoudoli, G.A., Jones, R.C. and Blow, J.J. (2011) MCM2-7 form double hexamers at licensed origins in Xenopus egg extract. J. Biol. Chem., 286, 11855-11864.
    • (2011) J. Biol. Chem. , vol.286 , pp. 11855-11864
    • Gambus, A.1    Khoudoli, G.A.2    Jones, R.C.3    Blow, J.J.4
  • 6
    • 33745925880 scopus 로고    scopus 로고
    • Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex a candidate for the eukaryotic DNA replication fork helicase
    • Moyer, S.E., Lewis, P.W. and Botchan, M.R. (2006) Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase. Proc. Natl Acad. Sci. USA, 103, 10236-10241.
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 10236-10241
    • Moyer, S.E.1    Lewis, P.W.2    Botchan, M.R.3
  • 7
    • 47349114465 scopus 로고    scopus 로고
    • The Mcm2-7 complex has in vitro helicase activity
    • Bochman, M.L. and Schwacha, A. (2008) The Mcm2-7 complex has in vitro helicase activity. Mol. Cell, 31, 287-293.
    • (2008) Mol. Cell , vol.31 , pp. 287-293
    • Bochman, M.L.1    Schwacha, A.2
  • 8
    • 0032969563 scopus 로고    scopus 로고
    • AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes
    • Neuwald, A.F., Aravind, L., Spouge, J.L. and Koonin, E.V. (1999) AAA+: a class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes. Genome Res., 9, 27-43.
    • (1999) Genome Res. , vol.9 , pp. 27-43
    • Neuwald, A.F.1    Aravind, L.2    Spouge, J.L.3    Koonin, E.V.4
  • 9
    • 29544446184 scopus 로고    scopus 로고
    • ATPase-dependent cooperative binding of ORC and Cdc6 to origin DNA
    • Speck, C., Chen, Z., Li, H. and Stillman, B. (2005) ATPase-dependent cooperative binding of ORC and Cdc6 to origin DNA. Nat. Struct. Mol. Biol., 12, 965-971.
    • (2005) Nat. Struct. Mol. Biol. , vol.12 , pp. 965-971
    • Speck, C.1    Chen, Z.2    Li, H.3    Stillman, B.4
  • 10
    • 29544435484 scopus 로고    scopus 로고
    • Sequential ATP hydrolysis by Cdc6 and ORC directs loading of the Mcm2-7 helicase
    • Randell, J.C., Bowers, J.L., Rodriguez, H.K. and Bell, S.P. (2006) Sequential ATP hydrolysis by Cdc6 and ORC directs loading of the Mcm2-7 helicase. Mol. Cell, 21, 29-39.
    • (2006) Mol. Cell , vol.21 , pp. 29-39
    • Randell, J.C.1    Bowers, J.L.2    Rodriguez, H.K.3    Bell, S.P.4
  • 11
    • 0034687677 scopus 로고    scopus 로고
    • Stepwise assembly of initiation proteins at budding yeast replication origins in vitro
    • Seki, T. and Diffley, J.F. (2000) Stepwise assembly of initiation proteins at budding yeast replication origins in vitro. Proc. Natl Acad. Sci. USA, 97, 14115-14120.
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 14115-14120
    • Seki, T.1    Diffley, J.F.2
  • 13
    • 29244451896 scopus 로고    scopus 로고
    • The ATPase activity of MCM2-7 is dispensable for pre-RC assembly but is required for DNA unwinding
    • Ying, C.Y. and Gautier, J. (2005) The ATPase activity of MCM2-7 is dispensable for pre-RC assembly but is required for DNA unwinding. EMBO J., 24, 4334-4344.
    • (2005) EMBO J. , vol.24 , pp. 4334-4344
    • Ying, C.Y.1    Gautier, J.2
  • 14
    • 83455235480 scopus 로고    scopus 로고
    • Multiple Cdt1 molecules act at each origin to load replication-competent Mcm2-7 helicases
    • Takara, T.J. and Bell, S.P. (2011) Multiple Cdt1 molecules act at each origin to load replication-competent Mcm2-7 helicases. EMBO J., 30, 4885-4896.
    • (2011) EMBO J. , vol.30 , pp. 4885-4896
    • Takara, T.J.1    Bell, S.P.2
  • 18
    • 29644436609 scopus 로고    scopus 로고
    • Double hexamer disruption and biochemical activities of Methanobacterium thermoautotrophicum MCM
    • Fletcher, R.J., Shen, J., Gomez-Llorente, Y., Martin, C.S., Carazo, J.M. and Chen, X.S. (2005) Double hexamer disruption and biochemical activities of Methanobacterium thermoautotrophicum MCM. J. Biol. Chem., 280, 42405-42410.
    • (2005) J. Biol. Chem. , vol.280 , pp. 42405-42410
    • Fletcher, R.J.1    Shen, J.2    Gomez-Llorente, Y.3    Martin, C.S.4    Carazo, J.M.5    Chen, X.S.6
  • 19
    • 48249084972 scopus 로고    scopus 로고
    • Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication
    • Ibarra, A., Schwob, E. and Mendez, J. (2008) Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication. Proc. Natl Acad. Sci. USA, 105, 8956-8961.
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 8956-8961
    • Ibarra, A.1    Schwob, E.2    Mendez, J.3
  • 20
    • 37249025795 scopus 로고    scopus 로고
    • Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress
    • Ge, X.Q., Jackson, D.A. and Blow, J.J. (2007) Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress. Genes Dev., 21, 3331-3341.
    • (2007) Genes Dev. , vol.21 , pp. 3331-3341
    • Ge, X.Q.1    Jackson, D.A.2    Blow, J.J.3
  • 21
    • 14544277626 scopus 로고    scopus 로고
    • Origin recognition and the chromosome cycle
    • Stillman, B. (2005) Origin recognition and the chromosome cycle. FEBS Lett., 579, 877-884.
    • (2005) FEBS Lett. , vol.579 , pp. 877-884
    • Stillman, B.1
  • 22
    • 36249005517 scopus 로고    scopus 로고
    • Orc6 is required for dynamic recruitment of Cdt1 during repeated Mcm2-7 loading
    • Chen, S., de Vries, M.A. and Bell, S.P. (2007) Orc6 is required for dynamic recruitment of Cdt1 during repeated Mcm2-7 loading. Genes Dev., 21, 2897-2907.
    • (2007) Genes Dev. , vol.21 , pp. 2897-2907
    • Chen, S.1    De Vries, M.A.2    Bell, S.P.3
  • 23
    • 61849173573 scopus 로고    scopus 로고
    • Incorporation into the prereplicative complex activates the Mcm2-7 helicase for Cdc7-Dbf4 phosphorylation
    • Francis, L.I., Randell, J.C., Takara, T.J., Uchima, L. and Bell, S.P. (2009) Incorporation into the prereplicative complex activates the Mcm2-7 helicase for Cdc7-Dbf4 phosphorylation. Genes Dev., 23, 643-654.
    • (2009) Genes Dev. , vol.23 , pp. 643-654
    • Francis, L.I.1    Randell, J.C.2    Takara, T.J.3    Uchima, L.4    Bell, S.P.5
  • 24
    • 78149462002 scopus 로고    scopus 로고
    • Mec1 is one of multiple kinases that prime the Mcm2-7 helicase for phosphorylation by Cdc7
    • Randell, J.C., Fan, A., Chan, C., Francis, L.I., Heller, R.C., Galani, K. and Bell, S.P. (2010) Mec1 is one of multiple kinases that prime the Mcm2-7 helicase for phosphorylation by Cdc7. Mol. Cell, 40, 353-363.
    • (2010) Mol. Cell , vol.40 , pp. 353-363
    • Randell, J.C.1    Fan, A.2    Chan, C.3    Francis, L.I.4    Heller, R.C.5    Galani, K.6    Bell, S.P.7
  • 25
    • 0026607331 scopus 로고
    • ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex
    • Bell, S.P. and Stillman, B. (1992) ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex. Nature, 357, 128-134.
    • (1992) Nature , vol.357 , pp. 128-134
    • Bell, S.P.1    Stillman, B.2
  • 26
    • 0029048775 scopus 로고
    • ORC and Cdc6p interact and determine the frequency of initiation of DNA replication in the genome
    • Liang, C., Weinreich, M. and Stillman, B. (1995) ORC and Cdc6p interact and determine the frequency of initiation of DNA replication in the genome. Cell, 81, 667-676.
    • (1995) Cell , vol.81 , pp. 667-676
    • Liang, C.1    Weinreich, M.2    Stillman, B.3
  • 27
    • 0030030623 scopus 로고    scopus 로고
    • An essential role for the Cdc6 protein in forming the pre-replicative complexes of budding yeast
    • Cocker, J.H., Piatti, S., Santocanale, C., Nasmyth, K. and Diffley, J.F. (1996) An essential role for the Cdc6 protein in forming the pre-replicative complexes of budding yeast. Nature, 379, 180-182.
    • (1996) Nature , vol.379 , pp. 180-182
    • Cocker, J.H.1    Piatti, S.2    Santocanale, C.3    Nasmyth, K.4    Diffley, J.F.5
  • 28
    • 34249739682 scopus 로고    scopus 로고
    • Cdc6 ATPase activity regulates ORC x Cdc6 stability and the selection of specific DNA sequences as origins of DNA replication
    • Speck, C. and Stillman, B. (2007) Cdc6 ATPase activity regulates ORC x Cdc6 stability and the selection of specific DNA sequences as origins of DNA replication. J. Biol. Chem., 282, 11705-11714.
    • (2007) J. Biol. Chem. , vol.282 , pp. 11705-11714
    • Speck, C.1    Stillman, B.2
  • 29
    • 0030271388 scopus 로고    scopus 로고
    • The Xenopus Cdc6 protein is essential for the initiation of a single round of DNA replication in cell-free extracts
    • Coleman, T.R., Carpenter, P.B. and Dunphy, W.G. (1996) The Xenopus Cdc6 protein is essential for the initiation of a single round of DNA replication in cell-free extracts. Cell, 87, 53-63.
    • (1996) Cell , vol.87 , pp. 53-63
    • Coleman, T.R.1    Carpenter, P.B.2    Dunphy, W.G.3
  • 30
    • 0036125511 scopus 로고    scopus 로고
    • Interdependent nuclear accumulation of budding yeast Cdt1 and Mcm2-7 during G1 phase
    • Tanaka, S. and Diffley, J.F. (2002) Interdependent nuclear accumulation of budding yeast Cdt1 and Mcm2-7 during G1 phase. Nat. Cell Biol., 4, 198-207.
    • (2002) Nat. Cell Biol. , vol.4 , pp. 198-207
    • Tanaka, S.1    Diffley, J.F.2
  • 31
    • 10944235448 scopus 로고    scopus 로고
    • ATP hydrolysis by ORC catalyzes reiterative Mcm2-7 assembly at a defined origin of replication
    • Bowers, J.L., Randell, J.C., Chen, S. and Bell, S.P. (2004) ATP hydrolysis by ORC catalyzes reiterative Mcm2-7 assembly at a defined origin of replication. Mol. Cell, 16, 967-978.
    • (2004) Mol. Cell , vol.16 , pp. 967-978
    • Bowers, J.L.1    Randell, J.C.2    Chen, S.3    Bell, S.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.