Metabolic engineering of Escherichia coli to enhance shikimic acid production from sorbitol

World Journal of Microbiology and Biotechnology

Volumn 30, Issue 9, 2014, Pages 2543-2550

  Liu, Xianglei ^a   Lin, Jun ^a   Hu, Haifeng ^a   Zhou, Bin ^a   Zhu, Baoquan ^a  

^a China State Institute of Pharmaceutical Industry   (China)

Author keywords

Escherichia coli; Red recombination; Shikimic acid; Sorbitol

Indexed keywords

CARBOXYLIC ACIDS; ENZYMES; ESCHERICHIA COLI; GENES;

HIGH EFFICIENT; LOW CONSUMPTION; METABOLIC PATHWAYS; RED RECOMBINATION; SHIKIMATE KINASE; SHIKIMIC ACIDS; SORBITOL; SYNTHETIC MATERIALS;

ALCOHOLS;

ESCHERICHIA COLI;

CARBON; RECOMBINANT PROTEIN; SHIKIMIC ACID; SORBITOL;

ESCHERICHIA COLI; GENE DELETION; GENE EXPRESSION; GENETICS; METABOLIC ENGINEERING; METABOLISM; PLASMID;

CARBON; ESCHERICHIA COLI; GENE DELETION; GENE EXPRESSION; METABOLIC ENGINEERING; METABOLIC NETWORKS AND PATHWAYS; PLASMIDS; RECOMBINANT PROTEINS; SHIKIMIC ACID; SORBITOL;

EID: 84905102220     PISSN: 09593993     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11274-014-1679-z     Document Type: Article

References (30)

1. Ahn JO, Lee HW, Saha R, Park MS, Jung JK, Lee DY (2008) Exploring the effects of carbon sources on the metabolic capacity for shikimic acid production in Escherichia coli using in silico metabolic predictions. J Microbiol Biotechnol 18(11): 1773-1784. doi: 10. 4014/jmb. 0700. 705.
2. Baba T, Ara T, Hasegawa M, Takai Y, Okumura Y, Baba M, Datsenko KA, Tomita M, Wanner BL, Mori H (2006) Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol Syst Biol 2(2006): 0008. doi: 10. 1038/msb4100050.
3. Bochkov DV, Sysolyatin SV, Kalashnikov AI, Surmacheva IA (2012) Shikimic acid: review of its analytical, isolation, and purification techniques from plant and microbial sources. J Chem Biol 5(1): 5-17. doi: 10. 1007/s12154-011-0064-8.
4. Chandran SS, Yi J, Draths KM, von Daeniken R, Weber W, Frost JW (2003) Phosphoenolpyruvate availability and the biosynthesis of shikimic acid. Biotechnol Prog 19(3): 808-814. doi: 10. 1021/bp025769p.
5. Chen K, Dou J, Tang S, Yang Y, Wang H, Fang H, Zhou C (2012) Deletion of the aroK gene is essential for high shikimic acid accumulation through the shikimate pathway in E. coli. Bioresour Technol 119: 141-147. doi: 10. 1016/j. biortech. 2012. 05. 100.
6. R cassettes with the option of Flp-catalyzed excision of the antibiotic-resistance determinant. Gene 158(1): 9-14. doi: 10. 1016/0378-1119(95)00193-A.
7. Cui YY, Ling C, Zhang YY, Huang J, Liu JZ (2014) Production of shikimic acid from Escherichia coli through chemically inducible chromosomal evolution and cofactor metabolic engineering. Microb Cell Fact 13: 21. doi: 10. 1186/1475-2859-13-21.
8. Datsenko KA, Wanner BL (2000) One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Natl Acad Sci USA 97(12): 6640-6645. doi: 10. 1073/pnas. 120163297.
9. Draths KM, Knop DR, Frost JW (1999) Shikimic acid and quinic acid replacing isolation from plant sources with recombinant microbial biocatalysis. J Am Chem Soc 12: 1603-1604. doi: 10. 1021/ja9830243.
10. Escalante A, Calderon R, Valdivia A, de Anda R, Hernandez G, Ramirez OT, Gosset G, Bolivar F (2010) Metabolic engineering for the production of shikimic acid in an evolved Escherichia coli strain lacking the phosphoenolpyruvate: carbohydrate phosphotransferase system. Microb Cell Fact 9: 21. doi: 10. 1186/1475-2859-9-21.
11. Estevez AM, Estevez RJ (2012) A short overview on the medicinal chemistry of (-)-shikimic acid. Mini Rev Med Chem 12(14): 1443-1454. doi: 10. 2174/138955712803832735.
12. Ghosh S, Chisti Y, Banerjee UC (2012) Production of shikimic acid. Biotechnol Adv 30(6): 1425-1431. doi: 10. 1016/j. biotechadv. 2012. 03. 001.
13. Herrmann KM, Weaver LM (1999) The shikimate pathway. Ann Rev Plant Physiol Plant Mol Biol 50: 473-503. doi: 10. 1146/annurev. arplant. 50. 1. 473.
14. Johansson L, Liden G (2006) Transcriptome analysis of a shikimic acid producing strain of Escherichia coli W3110 grown under carbon- and phosphate-limited conditions. J Biotechnol 126(4): 528-545. doi: 10. 1016/j. jbiotec. 2006. 05. 007.
15. Knop DR, Draths KM, Chandran SS, Barker JL, von Daeniken R, Weber W, Frost JW (2001) Hydroaromatic equilibration during biosynthesis of shikimic acid. J Am Chem Soc 123(42): 10173-10182. doi: 10. 1021/ja0109444.
16. Kramer M, Bongaerts J, Bovenberg R, Kremer S, Muller U, Orf S, Wubbolts M, Raeven L (2003) Metabolic engineering for microbial production of shikimic acid. Metab Eng 5(4): 277-283. doi: 10. 1016/j. ymben. 2003. 09. 001.
17. Li K, Frost JW (1999) Microbial synthesis of 3-dehydroshikimic acid: a comparative analysis of D-xylose, L-arabinose, and D-glucose carbon sources. Biotechnol Prog 15(5): 876-883. doi: 10. 1021/bp990095c.
18. Li K, Mikola MR, Draths KM, Worden RM, Frost JW (1999) Fed-batch fermentor synthesis of 3-dehydroshikimic acid using recombinant Escherichia coli. Biotechnol Bioeng 64(1): 61-73. doi: 10. 1002/(SICI)1097-0290(19990705)64: 1<61: AID-BIT7>3. 3. CO;2-7.
19. Lin H, Bennett GN, San KY (2005) Effect of carbon sources differing in oxidation state and transport route on succinate production in metabolically engineered Escherichia coli. J Ind Microbiol Biotechnol 32(3): 87-93. doi: 10. 1007/s10295-005-0206-5.
20. Lu J, Tang J, Liu Y, Zhu X, Zhang T, Zhang X (2012) Combinatorial modulation of galP and glk gene expression for improved alternative glucose utilization. Appl Microbiol Biotechnol 93(6): 2455-2462. doi: 10. 1007/s00253-011-3752-y.
21. Maeda H, Dudareva N (2012) The shikimate pathway and aromatic amino acid biosynthesis in plants. Ann Rev Plant Biol 63: 73-105. doi: 10. 1146/annurev-arplant-042811-105439.
22. Matsuda F, Ishii J, Kondo T, Ida K, Tezuka H, Kondo A (2013) Increased isobutanol production in Saccharomyces cerevisiae by eliminating competing pathways and resolving cofactor imbalance. Microb Cell Fact 12: 119. doi: 10. 1186/1475-2859-12-119.
23. Meza E, Becker J, Bolivar F, Gosset G, Wittmann C (2012) Consequences of phosphoenolpyruvate: sugar phosphotranferase system and pyruvate kinase isozymes inactivation in central carbon metabolism flux distribution in Escherichia coli. Microb Cell Fact 11: 127. doi: 10. 1186/1475-2859-11-127.
24. Perrakis A, Romier C (2008) Assembly of protein complexes by coexpression in prokaryotic and eukaryotic hosts: an overview. Methods Mol Biol 426: 247-256. doi: 10. 1007/978-1-60327-058-8_15.
25. Rawat G, Tripathi P, Jahan F, Saxena RK (2013a) A natural isolate producing shikimic acid: isolation, identification, and culture condition optimization. Appl Biochem Biotechnol 169(8): 2290-2302. doi: 10. 1007/s12010-013-0150-1.
26. Rawat G, Tripathi P, Saxena RK (2013b) Expanding horizons of shikimic acid: recent progresses in production and its endless frontiers in application and market trends. Appl Microbiol Biotechnol 97(10): 4277-4287. doi: 10. 1007/s00253-013-4840-y.
27. Saxena RK, Tripathi P, Rawat G (2012) Pandemism of swine flu and its prospective drug therapy. Eur J Clin Microbiol Infect Dis 31(12): 3265-3279. doi: 10. 1007/s10096-012-1716-5.
28. Shi A, Zhu X, Lu J, Zhang X, Ma Y (2012) Activating transhydrogenase and NAD kinase in combination for improving isobutanol production. Metab Eng 16C: 1-10. doi: 10. 1016/j. ymben. 2012. 11. 008.
29. Tripathi P, Rawat G, Yadav S, Saxena RK (2013) Fermentative production of shikimic acid: a paradigm shift of production concept from plant route to microbial route. Bioprocess Biosyst Eng 36(11): 1665-1673. doi: 10. 1007/s00449-013-0940-4.
30. Yi J, Draths KM, Li K, Frost JW (2003) Altered glucose transport and shikimate pathway product yields in E. coli. Biotechnol Prog 19(5): 1450-1459. doi: 10. 1021/bp0340584.