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Volumn 22, Issue 15, 2014, Pages 4083-4098
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Development of radamide analogs as Grp94 inhibitors
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Author keywords
Grp94; Hsp90
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Indexed keywords
GLUCOSE REGULATED PROTEIN 94;
HEAT SHOCK PROTEIN 90 INHIBITOR;
METHYL 2 [3 (BENZYLAMINO) 3 OXOPROPYL] 3 CHLORO 4,6 DIHYDROXYBENZOIC ACID;
METHYL 2 [3 ([1,10 BIPHENYL] 3 YLAMINO) 3 OXOPROPYL] 3 CHLORO 4,6 DIHYDROXYBENZOIC ACID;
METHYL 2 [3 [(2 AMINOPHENYL)AMINO] 3 OXOPROPYL] 3 CHLORO 4,6 DIHYDROXYBENZOIC ACID;
METHYL 2 [3 [(2 BROMOPHENYL)AMINO] 3 OXOPROPYL] 4,6 DIHYDROXYBENZOIC ACID;
METHYL 2 [3 [(3 ACETAMIDOPHENYL)AMINO] 3 OXOPROPYL] 3 CHLORO 4,6 DIHYDROXYBENZOIC ACID;
METHYL 2 [3 [(3 AMINOPHENYL)AMINO] 3 OXOPROPYL] 3 CHLORO 4,6 DIHYDROXYBENZOIC ACID;
METHYL 2 [3[(3 BROMOPHENYL)AMINO] 3 OXOPROPYL] 3 CHLORO 4,6 DIHYDROBENZOIC ACID;
METHYL 3 CHLORO 2 [3 (CYCLOHEXYLAMINO) 3 OXOPROPYL] 4,6 DIHYDROXYBENZOIC ACID;
METHYL 3 CHLORO 2 [3 [(2 CHLOROPHENYL)AMINO] 3 OXOPROPYL] 4,6 DIHYDROXYBENZOIC ACID;
METHYL 3 CHLORO 2 [3 [(3 CHLOROPHENYL)AMINO] 3 OXOPROPYL] 4,6 DIHYDROXYBENZOIC ACID;
METHYL 3 CHLORO 2 [3 [(3 FLUOROPHENYL)AMINO] 3 OXOPROPYL] 4,6 DIHYDROXYBENZOIC ACID;
METHYL 3 CHLORO 4,6 DIHYDROXY 2 (3 OXO 3 (PHENYLAMINO)PROPYL)BENZOIC ACID;
METHYL 3 CHLORO 4,6 DIHYDROXY 2 (3 [[2 YDROXYPHENYL)AMINO] 3 OXOPROPYL]BENZOIC ACID;
METHYL 3 CHLORO 4,6 DIHYDROXY 2 [3 OXO 3 (2 PHENYLHYDRAZINYL)PROPYL]BENZOIC ACID;
METHYL 3 CHLORO 4,6 DIHYDROXY 2 [3 OXO 3 (ORTHO TOLYLAMINO)PROPYL]BENZOIC ACID;
METHYL 3 CHLORO 4,6 DIHYDROXY 2 [3 OXO 3 (PHENETHYLAMINO)PROPYL]BENZOIC ACID;
METHYL 3 CHLORO 4,6 DIHYDROXY 2 [3 OXO 3 (PYRIDIN 2 YLAMINO)PROPYL]BENZOIC ACID;
METHYL 3 CHLORO 4,6 DIHYDROXY 2 [3 OXO 3 (THIAZOL 2 YLAMINO)PROPYL]BENZOIC ACID;
METHYL 3 CHLORO 4,6 DIHYDROXY 2 [3 OXO 3 [[2 (TRIFLUOROMETHYL)PHENYL]AMINO]PROPYL]BENZOIC ACID;
METHYL 3 CHLORO 4,6 DIHYDROXY 2 [3 [(2 IODOPHENYL)AMINO] 3 OXOPROPYL]BENZOIC ACID;
METHYL 3 CHLORO 4,6 DIHYDROXY 2 [3 [(3 HYDROXYPHENYL)AMINO]3 OXOPROPYL]BENZOIC ACID;
METHYL 3 CHLORO 4,6 DIHYDROXY 2 [3 [(3 METHOXYPHENYL)AMINO]3 OXOPROPYL]BENZOIC ACID;
METHYL 3 FLUORO 2 [3 [(2 CHLOROPHENYL)AMINO] 3 OXOPROPYL] 4,6 DIHYDROXYBENZOIC ACID;
METHYL 3-CHLORO 4,6 DIHYDROXY 2 [3 OXO 3 [[3 (TRIFLUOROMETHYL)PHENYL]AMINO]PROPYL]BENZOIC ACID;
METHYL 3CHLORO 4,6 DIHYDROXY 2 [3 [(2 METHOXYPHENYL)AMINO] 3 OXOPROPYL]BENZOIC ACID;
RADAMIDE DERIVATIVE;
RADICICOL;
UNCLASSIFIED DRUG;
UNINDEXED DRUG;
ACETANILIDE DERIVATIVE;
BENZOIC ACID DERIVATIVE;
GLUCOSE-REGULATED PROTEINS;
HEAT SHOCK PROTEIN 70;
MEMBRANE PROTEIN;
PROTEIN BINDING;
RADAMIDE;
ANTINEOPLASTIC ACTIVITY;
ANTIPROLIFERATIVE ACTIVITY;
ARTICLE;
BINDING AFFINITY;
BREAST CANCER CELL LINE;
CELL ASSAY;
CELL MIGRATION;
CONTROLLED STUDY;
DRUG PROTEIN BINDING;
DRUG SELECTIVITY;
DRUG STRUCTURE;
HYDROPHOBICITY;
METASTASIS POTENTIAL;
MULTIPLE MYELOMA CELL LINE;
STRUCTURE ACTIVITY RELATION;
SUBSTITUTION REACTION;
ANTAGONISTS AND INHIBITORS;
CELL MOTION;
CELL PROLIFERATION;
CHEMISTRY;
DRUG EFFECTS;
FLUORESCENCE POLARIZATION;
HUMAN;
ISOMERISM;
KINETICS;
METABOLISM;
TUMOR CELL LINE;
ACETANILIDES;
BENZOATES;
CELL LINE, TUMOR;
CELL MOVEMENT;
CELL PROLIFERATION;
FLUORESCENCE POLARIZATION;
HSP70 HEAT-SHOCK PROTEINS;
HUMANS;
ISOMERISM;
KINETICS;
MEMBRANE PROTEINS;
PROTEIN BINDING;
STRUCTURE-ACTIVITY RELATIONSHIP;
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EID: 84905094596
PISSN: 09680896
EISSN: 14643391
Source Type: Journal
DOI: 10.1016/j.bmc.2014.05.075 Document Type: Article |
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Times cited : (26)
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References (53)
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