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Volumn 74, Issue 13, 2009, Pages 4697-4704
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Synthesis and evaluation of radamide analogues, a chimera of radicicol and geldanamycin
a
a
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Author keywords
[No Author keywords available]
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Indexed keywords
ANTIPROLIFERATIVE ACTIVITIES;
ATP BINDING POCKETS;
CHEMICAL EQUATIONS;
GELDANAMYCIN;
IN-VITRO;
INHIBITORY ACTIVITY;
N-TERMINAL;
NATURAL PRODUCTS;
OPEN CHAIN;
RADICICOL;
SIGNALING PROTEINS;
STRUCTURE ACTIVITY RELATIONSHIPS;
TETHER LENGTHS;
UNSATURATED AMIDES;
AMIDES;
CHEMICAL REACTIONS;
UNSATURATED COMPOUNDS;
ADENOSINE TRIPHOSPHATE;
AMIDE;
ANTINEOPLASTIC AGENT;
GELDANAMYCIN;
HEAT SHOCK PROTEIN 90;
HEAT SHOCK PROTEIN 90 INHIBITOR;
QUINONE DERIVATIVE;
RADAMIDE DERIVATIVE;
RADICICOL;
RESORCINOL;
UNCLASSIFIED DRUG;
AMINO TERMINAL SEQUENCE;
ANTINEOPLASTIC ACTIVITY;
ARTICLE;
BINDING AFFINITY;
BINDING SITE;
CELL STRAIN MCF 7;
CONTROLLED STUDY;
DRUG PROTEIN BINDING;
DRUG SCREENING;
DRUG STRUCTURE;
DRUG SYNTHESIS;
HORNER WADSWORTH EMMONS REACTION;
HUMAN;
HUMAN CELL;
IN VITRO STUDY;
PROTEIN DEGRADATION;
PROTEIN SYNTHESIS INHIBITION;
STEREOCHEMISTRY;
STRUCTURE ACTIVITY RELATION;
ACETANILIDES;
ADENOSINE TRIPHOSPHATASES;
ANTINEOPLASTIC AGENTS;
BENZOATES;
BENZOQUINONES;
BINDING SITES;
BREAST NEOPLASMS;
CELL LINE, TUMOR;
CELL PROLIFERATION;
DRUG DESIGN;
FEMALE;
HSP90 HEAT-SHOCK PROTEINS;
HUMANS;
LACTAMS, MACROCYCLIC;
LACTONES;
MACROLIDES;
MOLECULAR STRUCTURE;
RECEPTOR, ERBB-2;
STRUCTURE-ACTIVITY RELATIONSHIP;
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EID: 67649586399
PISSN: 00223263
EISSN: None
Source Type: Journal
DOI: 10.1021/jo900278g Document Type: Article |
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Times cited : (24)
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References (12)
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