Design, synthesis, and biological evaluation of conformationally constrained cis-amide HSP90 inhibitors

Organic Letters

Volumn 11, Issue 11, 2009, Pages 2353-2356

  Duerfeldt, Adam S ^a   Brandt, Gary E L ^a   Blagg, Brian S J ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; AMIDE; ANTINEOPLASTIC AGENT; BENZOQUINONE DERIVATIVE; GELDANAMYCIN; HEAT SHOCK PROTEIN 90; MACROCYCLIC LACTAM;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG DESIGN; DRUG SCREENING; FEMALE; HUMAN; STEREOISOMERISM; SYNTHESIS;

ADENOSINE TRIPHOSPHATASES; AMIDES; ANTINEOPLASTIC AGENTS; BENZOQUINONES; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HSP90 HEAT-SHOCK PROTEINS; HUMANS; LACTAMS, MACROCYCLIC; MOLECULAR STRUCTURE; STEREOISOMERISM;

EID: 66149188136     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol900783m     Document Type: Article

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