Complexing Aβ prevents the cellular anomalies induced by the peptide alone

Journal of Molecular Neuroscience

Volumn 53, Issue 4, 2014, Pages 661-668

  Henriques, A G ^a   Oliveira, J M ^a   Gomes, B ^a   Ruivo, R ^a   Da Cruz E Silva, E F ^a   Da Cruz E Silva, O A B ^a  

^a UNIVERSITY OF AVEIRO   (Portugal)

Author keywords

Aggregation; Alzheimer's disease therapeutics; F actin; Fibril inhibition; Gelsolin; Laminin

Indexed keywords

ACTIN; AMYLOID BETA PROTEIN; GELSOLIN; LAMININ;

ANIMAL; CELL CULTURE; DRUG EFFECTS; HELA CELL LINE; HUMAN; METABOLISM; NERVE CELL; PROTEINOSIS; RAT; WISTAR RAT;

ACTINS; AMYLOID BETA-PEPTIDES; ANIMALS; CELLS, CULTURED; GELSOLIN; HELA CELLS; HUMANS; LAMININ; NEURONS; PROTEIN AGGREGATION, PATHOLOGICAL; RATS; RATS, WISTAR;

EID: 84905085258     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-014-0233-7     Document Type: Article

References (50)

1. Amador FC, Henriques AG, da Cruz e Silva OA, da Cruz e Silva EF (2004) Monitoring protein phosphatase 1 isoform levels as a marker for cellular stress. Neurotoxicol Teratol 26:387-395 (Pubitemid 38534471)
2. Atwood CS, Martins RN, Smith MA, Perry G (2002) Senile plaque composition and posttranslational modification of amyloid-beta peptide and associated proteins. Peptides 23:1343-1350 (Pubitemid 34786713)
3. Brody DL, Magnoni S, Schwetye KE et al (2008) Amyloid-beta dynamics correlate with neurological status in the injured human brain. Science 321:1221-1224
4. Bronfman FC, Garrido J, Alvarez A, Morgan C, Inestrosa NC (1996) Laminin inhibits amyloid-beta-peptide fibrillation. Neurosci Lett 218:201-203
5. Carlson CD, Czilli DL, Gitter BD (2000) Regulation of amyloid precursor protein processing by Abeta in human glioma cells. Neurobiol Aging 21:747-756
6. Carro E (2010) Gelsolin as therapeutic target in Alzheimer 's disease. Expert Opin Ther Targets 14:585-592
7. Chauhan VP, Ray I, Chauhan A, Wisniewski HM (1999) Binding of gelsolin, a secretory protein, to amyloid beta-protein. Biochem Biophys Res Commun 258:241-246 (Pubitemid 29287035)
8. Chauhan V, Ji L, Chauhan A (2008) Anti-amyloidogenic, anti-oxidant and anti-apoptotic role of gelsolin in Alzheimer 's disease. Biogerontology 9:381-389. doi: 10.1007/s10522-008-9169-z
9. da Cruz e Silva EF, da Cruz e Silva OA (2003) Protein phosphorylation and APP metabolism. Neurochem Res 28:1553-1561
10. Dahlgren KN, Manelli AM, Stine WB Jr, Baker LK, Krafft GA, LaDu MJ (2002) Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability. J Biol Chem 277:32046-32053 (Pubitemid 34969015)
11. Davis-Salinas J, Saporito-Irwin SM, Cotman CW, Van Nostrand WE (1995) Amyloid beta-protein induces its own production in cultured degenerating cerebrovascular smoothmuscle cells. J Neurochem65: 931-934
12. Drouet B, Pincon-Raymond M, Chambaz J, Pillot T (1999) Laminin 1 attenuates beta-amyloid peptide Abeta(1-40) neurotoxicity of cultured fetal rat cortical neurons. J Neurochem 73:742-749 (Pubitemid 29339849)
13. Gandy S, Caporaso G, Buxbaum J, Frangione B, Greengard P (1994) APP processing, a beta-amyloidogenesis, and the pathogenesis of Alzheimer 's disease. Neurobiol Aging 15:253-256 (Pubitemid 24120839)
14. Giuffrida ML, Caraci F, Pignataro B et al (2009) Beta-amyloid monomers are neuroprotective. J Neurosci 29:10582-10587
15. Glenner GG, Wong CW (1984) Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem Biophys Res Commun 120:885-890 (Pubitemid 14104991)
16. Guntert A, Campbell J, Saleem M et al (2010) Plasma gelsolin is decreased and correlates with rate of decline in Alzheimer 's disease. J Alzheimers Dis 21:585-596
17. Henriques AG, Vieira SI, Rebelo S, Domingues SC, da Cruz e Silva EF, da Cruz e Silva OA (2007) Isoform specific amyloid-beta protein precursor metabolism. J Alzheimers Dis 11:85-95 (Pubitemid 46376712)
18. Henriques AG, Vieira SI, Crespo-Lopez ME, Guiomar de Oliveira MA, da Cruz e Silva EF, da Cruz e Silva OA (2009a) Intracellular sAPP retention in response to Abeta is mapped to cytoskeleton-associated structures. J Neurosci Res 87:1449-1461
19. Henriques AG, Vieira SI, da Cruz e Silva EF (2009b) Abeta hinders nuclear targeting of AICD and Fe65 in primary neuronal cultures. J Mol Neurosci 39:248-255
20. Henriques AG, Vieira SI, da Cruz e Silva EF, da Cruz e Silva OA (2010) Abeta promotes Alzheimer 's disease-like cytoskeleton abnormalities with consequences to APP processing in neurons. J Neurochem 113:761-771
21. Hirko AC, Meyer EM, King MA, Hughes JA (2007) Peripheral transgene expression of plasma gelsolin reduces amyloid in transgenic mouse models of Alzheimer 's disease. Mol Ther 15:1623-1629 (Pubitemid 47289005)
22. Howard T, Chaponnier C, Yin H, Stossel T (1990) Gelsolin-actin interaction and actin polymerization in human neutrophils. J Cell Biol 110:1983-1991
23. Janmey PA, Chaponnier C, Lind SE, Zaner KS, Stossel TP, Yin HL (1985) Interactions of gelsolin and gelsolin-actin complexes with actin. Effects of calcium on actin nucleation, filament severing, and end blocking. Biochemistry 24:3714-3723 (Pubitemid 15011909)
24. Ji L, Chauhan A, Chauhan V (2008) Cytoplasmic gelsolin in pheochromocytoma-12 cells forms a complex with amyloid beta-protein. Neuroreport 19:463-466 (Pubitemid 351301606)
25. Kaether C, Haass C, Steiner H (2006) Assembly, trafficking and function of gamma-secretase. Neurodegener Dis 3:275-283
26. Kaminsky YG, Marlatt MW, Smith MA, Kosenko EA (2010) Subcellular and metabolic examination of amyloid-beta peptides in Alzheimer disease pathogenesis: evidence for Abeta(25-35). Exp Neurol 221: 26-37
27. Kulakowska A, Drozdowski W, Sadzynski A, Bucki R, Janmey PA (2008) Gelsolin concentration in cerebrospinal fluid from patients with multiple sclerosis and other neurological disorders. Eur J Neurol 15:584-588 (Pubitemid 351677512)
28. Kwiatkowski DJ, Mehl R, Izumo S, Nadal-Ginard B, Yin HL (1988) Muscle is the major source of plasma gelsolin. J Biol Chem 263: 8239-8243
29. Lee HG, Casadesus G, Zhu X, Takeda A, Perry G, Smith MA (2004) Challenging the amyloid cascade hypothesis: senile plaques and amyloid-beta as protective adaptations to Alzheimer disease. Ann N YAcad Sci 1019:1-4 (Pubitemid 38951274)
30. LeVine H 3rd (1993) Thioflavine T interaction with synthetic Alzheimer 's disease beta-amyloid peptides: detection of amyloid aggregation in solution. Protein Sci 2:404-410
31. Lorenzo A, Yankner BA (1994) Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red. Proc Natl Acad Sci U S A 91:12243-12247 (Pubitemid 24368641)
32. Matsuoka Y, Saito M, LaFrancois J et al (2003) Novel therapeutic approach for the treatment of Alzheimer's disease by peripheral administration of agents with an affinity to beta-amyloid. J Neurosci 23:29-33 (Pubitemid 36050401)
33. Mattson MP, Cheng B, Culwell AR, Esch FS, Lieberburg I, Rydel RE (1993) Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein. Neuron 10:243-254 (Pubitemid 23079546)
34. Meziane H, Dodart JC, Mathis C et al (1998) Memory-enhancing effects of secreted forms of the beta-amyloid precursor protein in normal and amnestic mice. Proc Natl Acad Sci U S A 95:12683-12688 (Pubitemid 28483825)
35. Monji A, Tashiro K, Yoshida I et al (1999) Laminin inhibits both Abeta40 and Abeta42 fibril formation but does not affect Abeta40 or Abeta42-induced cytotoxicity in PC12 cells. Neurosci Lett 266:85-88 (Pubitemid 29227330)
36. Monning U, Sandbrink R, Weidemann A, Banati RB, Masters CL, Beyreuther K (1995) Extracellular matrix influences the biogenesis of amyloid precursor protein in microglial cells. J Biol Chem 270:7104-7110
37. Moreno-Flores MT, Salinero O, Wandosell F (1998) BetaA amyloid peptide (25-35) induced APP expression in cultured astrocytes. J Neurosci Res 52:661-671 (Pubitemid 28300046)
38. Morgan C, Inestrosa NC (2001) Interactions of laminin with the amyloid beta peptide. Implications for Alzheimer 's disease. Braz J Med Biol Res 34:597-601 (Pubitemid 33606293)
39. Morgan C, Bugueno MP, Garrido J, Inestrosa NC (2002) Laminin affects polymerization, depolymerization and neurotoxicity of Abeta peptide. Peptides 23:1229-1240 (Pubitemid 34786702)
40. Paunio T (1994) Quantification of serum and cerebrospinal fluid gelsolin in familial amyloidosis, Finnish type (AGel). Amyloid 1:80-89
41. Pereira C, Ferreiro E, Cardoso SM, de Oliveira CR (2004) Cell degeneration induced by amyloid-beta peptides: implications for Alzheimer 's disease. J Mol Neurosci 23:97-104 (Pubitemid 41359192)
42. Pike CJ, Burdick D, Walencewicz AJ, Glabe CG, Cotman CW (1993) Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state. J Neurosci 13:1676-1687 (Pubitemid 23095409)
43. Qiao H, Koya RC, Nakagawa K et al (2005) Inhibition of Alzheimer's amyloid-beta peptide-induced reduction of mitochondrial membrane potential and neurotoxicity by gelsolin. Neurobiol Aging 26:849-855 (Pubitemid 40249487)
44. Ray I, Chauhan A, Wegiel J, Chauhan VP (2000) Gelsolin inhibits the fibrillization of amyloid beta-protein, and also defibrillizes its preformed fibrils. Brain Res 853:344-351 (Pubitemid 30035235)
45. Schmitt TL, Steiner E, Trieb K, Grubeck-Loebenstein B (1997) Amyloid beta-protein(25-35) increases cellular APP and inhibits the secretion of APPs in human extraneuronal cells. Exp Cell Res 234:336-340 (Pubitemid 27335175)
46. Soucek T, Cumming R, Dargusch R, Maher P, Schubert D (2003) The regulation of glucose metabolism by HIF-1 mediates a neuroprotective response to amyloid beta peptide. Neuron 39:43-56 (Pubitemid 36830947)
47. Tanaka J, Sobue K (1994) Localization and characterization of gelsolin in nervous tissues: gelsolin is specifically enriched in myelin-forming cells. J Neurosci 14:1038-1052 (Pubitemid 24081902)
48. Vassar R, Bennett BD, Babu-Khan S et al (1999) Beta-secretase cleavage of Alzheimer 's amyloid precursor protein by the transmembrane aspartic protease BACE. Science 286:735-741
49. Vieira SI, Rebelo S, Domingues SC, da Cruz e Silva EF, da Cruz e Silva OA (2009) S655 phosphorylation enhances APP secretory traffic. Mol Cell Biochem 328:145-154
50. Yan R, Han P, Miao H, Greengard P, Xu H (2001) The transmembrane domain of the Alzheimer 's beta-secretase (BACE1) determines its late Golgi localization and access to beta-amyloid precursor protein (APP) substrate. J Biol Chem 276:36788-36796