Gelsolin concentration in cerebrospinal fluid from patients with multiple sclerosis and other neurological disorders

European Journal of Neurology

Volumn 15, Issue 6, 2008, Pages 584-588

  Kulakowska, A ^a   Drozdowski, W ^a   Sadzynski, A ^b   Bucki, R ^c   Janmey, P A ^c  

^a MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

^b Suwalki's District Hospital   (Poland)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Cerebrospinal fluid; Human; Plasma gelsolin

Indexed keywords

G ACTIN; GELSOLIN;

ACTIN POLYMERIZATION; ARTICLE; BELL PALSY; CEREBROSPINAL FLUID ANALYSIS; CLINICAL ARTICLE; DIAGNOSTIC VALUE; HEADACHE; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; INTERVERTEBRAL DISK DEGENERATION; ISCHIALGIA; MULTIPLE SCLEROSIS; NEUROLOGIC DISEASE; PRIORITY JOURNAL; RADIAL NEUROPATHY; SUBARACHNOID HEMORRHAGE;

BIOLOGICAL MARKERS; GELSOLIN; HUMANS; IMMUNOBLOTTING; MULTIPLE SCLEROSIS; NERVOUS SYSTEM DISEASES;

EID: 43549107082     PISSN: 13515101     EISSN: 14681331     Source Type: Journal    
DOI: 10.1111/j.1468-1331.2008.02133.x     Document Type: Article

References (38)

1. Huhmer AF, Biringer RG, Amato H, Fonteh AN, Harrington MG. Protein analysis in human cerebrospinal fluid: physiological aspects, current progress and future challenges. Disease Markers 2006 22 : 3 26.
2. Maury CP, Sletten K, Totty N, Kangas H, Liljestrom M. Identification of the circulating amyloid precursor and other gelsolin metabolites in patients with G654A mutation in the gelsolin gene (Finnish familial amyloidosis): pathogenetic and diagnostic implications. Laboratory Investigation 1997 77 : 299 304.
3. Paunio T, Kangas H, Heinonen O, et al. Cells of the neuronal lineage play a major role in the generation of amyloid precursor fragments in gelsolin-related amyloidosis. Journal of Biological Chemistry 1998 273 : 16319 16324.
4. Piubelli C, Fiorini M, Zanusso G, et al. Searching for markers of Creutzfeldt-Jakob disease in cerebrospinal fluid by two-dimensional mapping. Proteomics 2006 6 (Suppl. 1 S256 S261.
5. Rozek W, Ricardo-Dukelow M, Holloway S, et al. Cerebrospinal fluid proteomic profiling of HIV-1-infected patients with cognitive impairment. Journal of Proteome Research 2007 6 : 4189 4199.
6. Yuan X, Desiderio DM. Proteomics analysis of phosphotyrosyl-proteins in human lumbar cerebrospinal fluid. Journal of Proteome Research 2003 2 : 476 487.
7. Noben JP, Dumont D, Kwasnikowska N, et al. Lumbar cerebrospinal fluid proteome in multiple sclerosis: characterization by ultrafiltration, liquid chromatography, and mass spectrometry. Journal of Proteome Research 2006 5 : 1647 1657.
8. Yin HL, Stossel TP. Control of cytoplasmic actin gel-sol transformation by gelsolin, a calcium-dependent regulatory protein. Nature 1979 281 : 583 586.
9. Janmey PA, Stossel TP. Gelsolin-polyphosphoinositide interaction. Full expression of gelsolin-inhibiting function by polyphosphoinositides in vesicular form and inactivation by dilution, aggregation, or masking of the inositol head group. Journal of Biological Chemistry 1989 264 : 4825 4831.
10. Harris HE, Weeds AG. Plasma gelsolin caps and severs actin filaments. FEBS Letters 1984 177 : 184 188.
11. Kwiatkowski DJ. Functions of gelsolin: motility, signaling, apoptosis, cancer. Current Opinion in Cell Biology 1999 11 : 103 108.
12. Smith DB, Janmey PA, Lind SE. Circulating actin-gelsolin complexes following oleic acid-induced lung injury. American Journal of Pathology 1988 130 : 261 267.
13. Kwiatkowski DJ, Mehl R, Izumo S, Nadal-Ginard B, Yin HL. Muscle is the major source of plasma gelsolin. Journal of Biological Chemistry 1988 263 : 8239 8243.
14. Janmey PA, Lind SE, Yin HL, Stossel TP. Effects of semi-dilute actin solutions on the mobility of fibrin protofibrils during clot formation. Biochimica et Biophysica Acta 1985 841 : 151 158.
15. Haddad JG, Harper KD, Guoth M, Pietra GG, Sanger JW. Angiopathic consequences of saturating the plasma scavenger system for actin. Proceedings of the National Academy of Sciences U S A 1990 87 : 1381 1385.
16. Lind SE, Smith CJ. Actin is a noncompetitive plasmin inhibitor. Journal of Biological Chemistry 1991 266 : 5273 5278.
17. Lee WM, Galbraith RM. The extracellular actin-scavenger system and actin toxicity. New England Journal of Medicine 1992 326 : 1335 1341.
18. Goetzl EJ, Lee H, Azuma T, et al. Gelsolin binding and cellular presentation of lysophosphatidic acid. Journal of Biological Chemistry 2000 275 : 14573 14578.
19. Osborn TM, Dahlgren C, Hartwig JH, Stossel TP. Modifications of cellular responses to lysophosphatidic acid and platelet-activating factor by plasma gelsolin. American Journal of Physiology. Cell Physiology 2007 292 : C1323 C1330.
20. Bucki R, Georges PC, Espinassous Q, et al. Inactivation of endotoxin by human plasma gelsolin. Biochemistry 2005 44 : 9590 9597.
21. Lee PS, Waxman AB, Cotich KL, Chung SW, Perrella MA, Stossel TP. Plasma gelsolin is a marker and therapeutic agent in animal sepsis. Critical Care Medicine 2007 35 : 849 855.
22. Mounzer KC, Moncure M, Smith YR, DiNubile MJ. Relationship of admission plasma gelsolin levels to clinical outcomes in patients after major trauma. American Journal of Respiratory and Critical Care Medicine 1999 160 : 1673 1681.
23. Lind SE, Smith DB, Janmey PA, Stossel TP. Depression of gelsolin levels and detection of gelsolin-actin complexes in plasma of patients with acute lung injury. American Review of Respiratory Disease 1988 138 : 429 434.
24. Christofidou-Solomidou M, Scherpereel A, Solomides CC, et al. Changes in plasma gelsolin concentration during acute oxidant lung injury in mice. Lung 2002 180 : 91 104.
25. Smith DB, Janmey PA, Sherwood JA, Howard RJ, Lind SE. Decreased plasma gelsolin levels in patients with Plasmodium falciparum malaria: a consequence of hemolysis? Blood 1988 72 : 214 218.
26. Ito H, Kambe H, Kimura Y, et al. Depression of plasma gelsolin level during acute liver injury. Gastroenterology 1992 102 : 1686 1692.
27. Suhler E, Lin W, Yin HL, Lee WM. Decreased plasma gelsolin concentrations in acute liver failure, myocardial infarction, septic shock, and myonecrosis. Critical Care Medicine 1997 25 : 594 598.
28. DiNubile MJ. Plasma gelsolin: in search of its raison d'etre. Focus on "modifications of cellular responses to lysophosphatidic acid and platelet-activating factor by plasma gelsolin". American Journal of Physiology. Cell Physiology 2007 292 : C1240 C1242.
29. Kurtzke JF. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 1983 33 : 1444 1452.
30. Spudich JA, Watt S. The regulation of rabbit skeletal muscle contraction. I. Biochemical studies of the interaction of the tropomyosin-troponin complex with actin and the proteolytic fragments of myosin. Journal of Biological Chemistry 1971 246 : 4866 4871.
31. Kouyama T, Mihashi K. Fluorimetry study of N-(1-pyrenyl)iodoacetamide- labelled F-actin. Local structural change of actin protomer both on polymerization and on binding of heavy meromyosin. European Journal of Biochemistry 1981 114 : 33 38.
32. DiNubile MJ, Stossel TP, Ljunghusen OC, Ferrara JL, Antin JH. Prognostic implications of declining plasma gelsolin levels after allogeneic stem cell transplantation. Blood 2002 100 : 4367 4371.
33. Jiang L, Lindpaintner K, Li HF, et al. Proteomic analysis of the cerebrospinal fluid of patients with schizophrenia. Amino Acids 2003 25 : 49 57.
34. Dumont D, Noben JP, Raus J, Stinissen P, Robben J. Proteomic analysis of cerebrospinal fluid from multiple sclerosis patients. Proteomics 2004 4 : 2117 2124.
35. Baraniuk JN, Casado B, Maibach H, Clauw DJ, Pannell LK, Hess SS. A chronic fatigue syndrome - elated proteome in human cerebrospinal fluid. BioMed Central Neurology 2005 5 : 22 26.
36. Kappos L, Antel J, Comi G, et al. Oral fingolimod (FTY720) for relapsing multiple sclerosis. New England Journal of Medicine 2006 355 : 1124 1140.
37. Janmey PA, Bucki R. Methods of using gelsolin to treat or prevent bacterial sepsis. US patent application 20070238668 514015000 (USPTO) Trustees of the University of Pennsylvania, USA 2006. http://www.freshpatents.com (Accessed January 25; 2008).
38. Lofberg M, Paunio T, Tahtela R, Kiuru S, Somer H. Serum gelsolin and rhabdomyolysis. Journal of Neurological Sciences 1998 157 : 187 190.