Phosphatase of regenerating liver 2 (PRL2) is essential for placental development by down-regulating PTEN (phosphatase and tensin homologue deleted on chromosome 10) and activating Akt protein

Journal of Biological Chemistry

Volumn 287, Issue 38, 2012, Pages 32172-32179

  Dong, Yuanshu ^a   Zhang, Lujuan ^a   Zhang, Sheng ^a   Bai, Yunpeng ^a   Chen, Hanying ^a   Sun, Xiaoxin ^a   Yong, Weidong ^a   Li, Wei ^a   Colvin, Stephanie C ^a   Rhodes, Simon J ^a   Shou, Weinian ^a   Zhang, Zhong Yin ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AKT ACTIVATION; BIOCHEMICAL ANALYSIS; FETAL GROWTH RETARDATION; IN-VIVO; PHOSPHATASE AND TENSIN HOMOLOGUE DELETED ON CHROMOSOME 10; PHOSPHATASE OF REGENERATING LIVERS; PROTEASOMES; STRUCTURAL DEFECT; TUMOR SUPPRESSORS;

ACTIVATION ANALYSIS; CELL PROLIFERATION;

PHOSPHATASES;

PHOSPHATASE; PHOSPHATASE OF REGENERATING LIVER 2; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HYPOTROPHY; INTRAUTERINE GROWTH RETARDATION; MOUSE; NONHUMAN; PLACENTA DEVELOPMENT; PLACENTA INSUFFICIENCY; PRIORITY JOURNAL; SPONGIOTROPHOBLAST; TROPHOBLAST;

ALLELES; ANGIOGENIC PROTEINS; ANIMALS; CELL MOVEMENT; CELL PROLIFERATION; CYCLOHEXIMIDE; EMBRYONIC STEM CELLS; FEMALE; HEK293 CELLS; HUMANS; IMMEDIATE-EARLY PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; ONCOGENE PROTEINS; PLACENTA; PREGNANCY; PREGNANCY, ANIMAL; PROTEIN TYROSINE PHOSPHATASES; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; TROPHOBLASTS;

EID: 84866346272     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.393462     Document Type: Article

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