A complex of α6 integrin and E-cadherin drives liver metastasis of colorectal cancer cells through hepatic angiopoietin-like 6

EMBO Molecular Medicine

Volumn 4, Issue 11, 2012, Pages 1156-1175

  Marchiò, Serena ^a,b,c   Soster, Marco ^a,b   Cardaci, Sabrina ^a,b   Muratore, Andrea ^b   Bartolini, Alice ^a,b   Barone, Vanessa ^a,b   Ribero, Dario ^d   Monti, Maria ^e   Bovino, Paola ^a,b   Sun, Jessica ^f   Giavazzi, Raffaella ^g   Asioli, Sofia ^h   Cassoni, Paola ^h   Capussotti, Lorenzo ^d   Pucci, Piero ^e   Bugatti, Antonella ⁱ   Rusnati, Marco ⁱ   Pasqualini, Renata ^f   Arap, Wadih ^f   Bussolino, Federico ^a,b,c  

^a UNIVERSITY OF TURIN   (Italy)

^b CANDIOLO CANCER INSTITUTE   (Italy)

^c APAvadis Biotechnologies Srl   (Italy)

^d MAURIZIANO HOSPITAL   (Italy)

^e UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^f UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^g MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^h UNIVERSITY OF TURIN   (Italy)

ⁱ UNIVERSITY OF BRESCIA   (Italy)

Author keywords

6 integrin; Angiopoietin like 6; E cadherin; Metastatic colorectal cancer; Microenvironment

Indexed keywords

ALPHA6 INTEGRIN; ANGIOPOIETIN LIKE 6; GLYCOPROTEIN; PEPTIDE; UNCLASSIFIED DRUG; UVOMORULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER GROWTH; CELL HOMING; CIRCULATING TUMOR CELL; CLINICAL ARTICLE; COLORECTAL CANCER; COMPLEX FORMATION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER METASTASIS; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PEPTIDE LIBRARY; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; TUMOR MICROENVIRONMENT;

AMINO ACID MOTIFS; ANGIOPOIETINS; ANIMALS; BLOOD VESSELS; CADHERINS; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; FEMALE; HUMANS; INTEGRIN ALPHA6; LIVER; LIVER NEOPLASMS; MICE; MICE, NUDE; NEOPLASM METASTASIS; PROTEIN BINDING;

EID: 84868319447     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.201101164     Document Type: Article

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