A nanoparticle formula for delivering siRNA or miRNAs to tumor cells in cell culture and in vivo

Nature Protocols

Volumn 9, Issue 8, 2014, Pages 1900-1915

  Choi, Ki Young ^a,b   Silvestre, Oscar F ^a   Huang, Xinglu ^a   Hida, Naoki ^a   Liu, Gang ^a,c   Ho, Don N ^a   Lee, Seulki ^a,d   Lee, Sang Wook ^e   Hong, Jong In ^e   Chen, Xiaoyuan ^a  

^a NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING   (United States)

^b Massachusetts Institute of Technology Cambridge   (United States)

^c XIAMEN UNIVERSITY   (China)

^d JOHNS HOPKINS UNIVERSITY   (United States)

^e Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; CARBOXYL GROUP; FUNCTIONAL GROUP; HYALURONIC ACID; MICRORNA; MICRORNA 34A; NANOPARTICLE; OLIGORIBONUCLEOTIDE; SMALL INTERFERING RNA; THIOL GROUP; UNCLASSIFIED DRUG; ZINC DIPICOLYLAMINE DERIVATIVE; ORGANOMETALLIC COMPOUND; PICOLINE DERIVATIVE; ZN(II) DIPICOLYLAMINE;

ARTICLE; CANCER TISSUE; CELL TRANSPORT; CONJUGATION; CONTROLLED STUDY; COVALENT BOND; EXPERIMENTAL DESIGN; FLUC GENE; GENE DELIVERY SYSTEM; GENE SILENCING; HUMAN; HUMAN CELL; HYDRODYNAMICS; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; MALE; NANOANALYSIS; NANOENCAPSULATION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; REPORTER GENE; RNA SEQUENCE; STRUCTURE ANALYSIS; TUMOR CELL CULTURE; ANIMAL; CHEMISTRY; CULTURE TECHNIQUE; FEMALE; GENE THERAPY; HCT116 CELL LINE; NUDE MOUSE; PROCEDURES; RNA INTERFERENCE; TUMOR CELL LINE;

ANIMALS; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; FEMALE; GENETIC THERAPY; HCT116 CELLS; HUMANS; HYALURONIC ACID; MICE, NUDE; MICRORNAS; NANOPARTICLES; ORGANOMETALLIC COMPOUNDS; PICOLINES; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84905024272     PISSN: 17542189     EISSN: 17502799     Source Type: Journal    
DOI: 10.1038/nprot.2014.128     Document Type: Article

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