Reactive oxygen species and the bacterial response to lethal stress

Current Opinion in Microbiology

Volumn 21, Issue , 2014, Pages 1-6

  Zhao, Xilin ^a,b   Drlica, Karl ^b  

^a XIAMEN UNIVERSITY   (China)

^b RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; ANTIOXIDANT; REACTIVE OXYGEN METABOLITE; AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT; BETA LACTAM ANTIBIOTIC; POLYMYXIN DERIVATIVE; QUINOLONE DERIVATIVE;

ANTIBACTERIAL ACTIVITY; APOPTOSIS; BACTERIAL CELL; BACTERIUM; CELL DEATH; DIET SUPPLEMENTATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; OXIDATIVE STRESS; REVIEW; BACTERIAL GROWTH; BACTERICIDAL ACTIVITY; BACTERIOSTASIS; CELLULAR STRESS RESPONSE; LETHALITY; LIPID PEROXIDATION; MOLECULAR PROBE; DRUG EFFECTS; METABOLISM; SIGNAL TRANSDUCTION; THEORETICAL MODEL;

ANTI-BACTERIAL AGENTS; BACTERIA; MODELS, THEORETICAL; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84904915069     PISSN: 13695274     EISSN: 18790364     Source Type: Journal    
DOI: 10.1016/j.mib.2014.06.008     Document Type: Review

References (45)

1. Imlay J.A. Pathways of oxidative damage. Annu Rev Microbiol 2003, 57:395-418.
2. Greenberg J.T., Monach P., Chou J.H., Josephy P.D., Demple B. Positive control of a global antioxidant defense regulon activated by superoxide-generating agents in Escherichia coli. Proc Natl Acad Sci U S A 1990, 87:6181-6185.
3. Oethinger M., Podglajen I., Kern W.V., Levy S.B. Overexpression of the marA or soxS regulatory gene in clinical topoisomerase mutants of Escherichia coli. Antimicrob Agents Chemother 1998, 42:2089-2094.
4. Koutsolioutsou A., Martins E.A., White D.G., Levy S.B., Demple B. A soxRS-constitutive mutation contributing to antibiotic resistance in a clinical isolate of Salmonella enterica (Serovar typhimurium). Antimicrob Agents Chemother 2001, 45:38-43.
5. Goswami M., Mangoli S.H., Jawali N. Involvement of reactive oxygen species in the action of ciprofloxacin against Escherichia coli. Antimicrob Agents Chemother 2006, 50:949-954.
6. Goswami M., Mangoli S.H., Jawali N. Effects of glutathione and ascorbic acid on streptomycin sensitivity of Escherichia coli. Antimicrob Agents Chemother 2007, 51:1119-1122.
7. Albesa I., Becerra M.C., Battan P.C., Paez P.L. Oxidative stress involved in the antibacterial action of different antibiotics. Biochem Biophys Res Commun 2004, 317:605-609.
8. Becerra M.C., Albesa I. Oxidative stress induced by ciprofloxacin in Staphylococcus aureus. Biochem Biophys Res Commun 2002, 297:1003-1007.
9. Kohanski M.A., Dwyer D.J., Hayete B., Lawrence C.A., Collins J.J. A common mechanism of cellular death induced by bactericidal antibiotics. Cell 2007, 130:797-810.
10. Lewin C.S., Morrissey I., Smith J.T. The mode of action of quinolones: the paradox in activity of low and high concentrations and activity in the anaerobic environment. Eur J Clin Microbiol Infect Dis 1991, 10:240-248.
11. Malik M., Hussain S., Drlica K. Effect of anaerobic growth on quinolone lethality with Escherichia coli. Antimicrob Agents Chemother 2007, 51:28-34.
12. Wang X., Zhao X. Contribution of oxidative damage to antimicrobial lethality. Antimicrob Agents Chemother 2009, 53:1395-1402.
13. Liu Y., Liu X., Qu Y., Wang X., Li L., Zhao X. Inhibitors of reactive oxygen species accumulation delay and/or reduce the lethality of several antistaphylococcal agents. Antimicrob Agents Chemother 2012, 56:6048-6050.
14. Burger R.M., Drlica K. Superoxide protects Escherichia coli from bleomycin mediated lethality. J Inorg Biochem 2009, 103:1273-1277.
15. Mosel M., Li L., Drlica K., Zhao X. Superoxide-mediated protection of Escherichia coli from antimicrobials. Antimicrob Agents Chemother 2013, 57:5755-5759.
16. Farr S.B., Natvig D.O., Kogoma T. Toxicity and mutagenicity of plumbagin and the induction of a possible new DNA repair pathway in Escherichia coli. J Bacteriol 1985, 164:1309-1316.
17. Wang X., Zhao X., Malik M., Drlica K. Contribution of reactive oxygen species to pathways of quinolone-mediated bacterial cell death. J Antimicrobial Chemother 2010, 65:520-524.
18. Becerra M.C., Paez P.L., Larovere L.E., Albesa I. Lipids and DNA oxidation in Staphylococcus aureus as a consequence of oxidative stress generated by ciprofloxacin. Mol Cell Biochem 2006, 285:29-34.
19. Ling J., Cho C., Guo L.T., Aerni H.R., Rinehart J., Soll D. Protein aggregation caused by aminoglycoside action is prevented by a hydrogen peroxide scavenger. Mol Cell 2012, 48:713-722.
20. Foti J.J., Devadoss B., Winkler J.A., Collins J.J., Walker G.C. Oxidation of the guanine nucleotide pool underlies cell death by bactericidal antibiotics. Science 2012, 336:315-319.
21. Gusarov I., Shatalin K., Starodubtseva M., Nudler E. Endogenous nitric oxide protects bacteria against a wide spectrum of antibiotics. Science 2009, 325:1380-1384.
22. Shatalin K., Shatalina E., Mironov A., Nudler E. H2S: a universal defense against antibiotics in bacteria. Science 2011, 334:986-990.
23. Keren I., Wu Y., Inocencio J., Mulcahy L.R., Lewis K. Killing by bactericidal antibiotics does not depend on reactive oxygen species. Science 2013, 339:1213-1216.
24. Ezraty B., Vergnes A., Banzhaf M., Duverger Y., Huguenot A., Brochado A.R., Su S.Y., Espinosa L., Loiseau L., Py B., et al. Fe-S cluster biosynthesis controls uptake of aminoglycosides in a ROS-less death pathway. Science 2013, 340:1583-1587.
25. Mahoney T.F., Silhavy T.J. The Cpx stress response confers resistance to some, but not all, bactericidal antibiotics. J Bacteriol 2013, 195:1869-1874.
26. Dorsey-Oresto A., Lu T., Mosel M., Wang X., Salz T., Drlica K., Zhao X. YihE kinase is a central regulator of programmed cell death in bacteria. Cell Rep 2013, 3:528-537.
27. Kohanski M.A., Dwyer D.J., Wierzbowski J., Cottarel G., Collins J.J. Mistranslation of membrane proteins and two-component system activation trigger antibiotic-mediated cell death. Cell 2008, 135:679-690.
28. Davies B.W., Kohanski M.A., Simmons L.A., Winkler J.A., Collins J.J., Walker G.C. Hydroxyurea induces hydroxyl radical-mediated cell death in Escherichia coli. Mol Cell 2009, 36:845-860.
29. Liu Y., Imlay J.A. Cell death from antibiotics without the involvement of reactive oxygen species. Science 2013, 339:1210-1213.
30. Dwyer D.J., Belenky P., Yang J.H., MacDonald I.C., Martell J.D., Takahashi N., Chan C.T.Y., Lobritz M.A., Braff D., Schwarz E.G., et al. Antibiotics induce redox-related physiological alterations as part of their lethality. Proc Natl Acad Sci U S A 2014, 111:E2100-E2109.
31. Wu Y., Vulic M., Keren I., Lewis K. Role of oxidative stress in persister tolerance. Antimicrob Agents Chemother 2012, 56:4922-4926.
32. Lewis K. Persister cells. Annu Rev Microbiol 2010, 64:357-372.
33. Zhang Y., Zhang J., Hoeflich K.P., Ikura M., Qing G., Inouye M. MazF cleaves cellular mRNAs specifically at ACA to block protein synthesis in Escherichia coli. Mol Cell 2003, 12:913-923.
34. Gerdes K., Christensen S.K., Lobner-Olesen A. Prokaryotic toxin-antitoxin stress response loci. Nat Rev Microbiol 2005, 3:371-382.
35. Pogliano J., Lynch A.S., Belin D., Lin E.C., Beckwith J. Regulation of Escherichia coli cell envelope proteins involved in protein folding and degradation by the Cpx two-component system. Genes Dev 1997, 11:1169-1182.
36. Raivio T.L., Silhavy T.J. Periplasmic stress and ECF sigma factors. Annu Rev Microbiol 2001, 55:591-624.
37. Engelberg-Kulka H., Amitai S., Kolodkin-Gal I., Hazan R. Bacterial programmed cell death and multicellular behavior in bacteria. PLoS Genet 2006, 2:e135.
38. Pedersen K., Christensen S.K., Gerdes K. Rapid induction and reversal of a bacteriostatic condition by controlled expression of toxins and antitoxins. Mol Microbiol 2002, 45:501-510.
39. Wu X., Wang X., Drlica K., Zhao X. A toxin-antitoxin module in Bacillus subtilis can both mitigate and amplify effects of lethal stress. PLoS One 2011, 6:e23909.
40. Marathe S.A., Kumar R., Ajitkumar P., Nagaraja V., Chakravortty D. Curcumin reduces the antimicrobial activity of ciprofloxacin against Salmonella typhimurium and Salmonella typhi. J Antimicrob Chemother 2013, 68:139-152.
41. Radimer K., Bindewald B., Hughes J., Ervin B., Swanson C., Picciano M.F. Dietary supplement use by US adults: data from the National Health and Nutrition Examination Survey, 1999-2000. Am J Epidemiol 2004, 160:339-349.
42. Holden J.K., Li H., Jing Q., Kang S., Richo J., Silverman R.B., Poulos T.L. Structural and biological studies on bacterial nitric oxide synthase inhibitors. Proc Natl Acad Sci U S A 2013, 110:18127-18131.
43. Brynildsen M.P., Winkler J.A., Spina C.S., MacDonald I.C., Collins J.J. Potentiating antibacterial activity by predictably enhancing endogenous microbial ROS production. Nat Biotechnol 2013, 31:160-165.
44. Yeom J., Imlay J.A., Park W. Iron homeostasis affects antibiotic-mediated cell death in Pseudomonas species. J Biol Chem 2010, 285:22689-22695.
45. Sampson T.R., Liu X., Schroeder M.R., Kraft C.S., Burd E.M., Weiss D.S. Rapid killing of Acinetobacter baumannii by polymyxins is mediated by a hydroxyl radical death pathway. Antimicrob Agents Chemother 2012, 56:5642-5649.