Regulation of Escherichia coli cell envelope proteins involved in protein folding and degradation by the Cpx two-component system

Genes and Development

Volumn 11, Issue 9, 1997, Pages 1169-1182

  Pogliano, Joe ^a,d   Lynch, A Simon ^a,c   Belin, Dominique ^b   Lin, E C C ^a   Beckwith, Jon ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^c AMGEN INC   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cpx; DegP; DsbA; protein folding; transcription

Indexed keywords

ENVELOPE PROTEIN;

ARTICLE; BACTERIAL GENE; BACTERIAL MEMBRANE; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FOLDING; TRANSCRIPTION REGULATION;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0030992719     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.11.9.1169     Document Type: Article

References (66)

1. Babior, B.M. 1992. The respiratory burst oxidase. Enzymol. Rel. Areas Mol. Biol. 65: 49-65.
2. Badwey, J.A. and M.L. Karnovsky. 1980. Active oxygen species and the functions of phagocytic leukocytes. Annu. Rev. Biochem. 49: 695-726.
3. Bardwell, J.C.A., K. McGovern, and J. Beckwith. 1991. Identification of a protein required for disulfide bond formation in vivo. Cell 67: 581-589.
4. Bardwell, J.C.A., J. Lee, G. Jander, N. Martin, D. Belin, and J. Beckwith. 1993. A pathway for disulfide bond formation in vivo. Proc. Natl. Acad. Sci. 90: 1038-1042.
5. Baumler, A.J., J.G. Kusters, I. Stojiljkovic, and F. Heffron. 1994. Salmonella typhimurium loci involved in survival within macrophages. Infect. Immun. 62: 1623-1630.
6. Belin, D. 1996a. The preparation of riboprobes. Basic DNA and RNA protocols Methods Mol. Biol. 58: 83-91.
7. _. 1996b. The RNase protection assay. Basic DNA and RNA protocols. Methods Mol. Biol. 58: 131-136.
8. Belin, D., J. Hedgpeth, G.B Selzer, and R.H. Epstein. 1979. Temperature-sensitive mutation in the initiation codon of the rIIB gene of bacteriophage T4. Proc. Natl. Acad. Sci. 76: 700-704.
9. Belin, P. and P.L. Boquet. 1994. The Escherichia coli dsbA gene is partly transcribed from the promoter of a weakly expressed upstream gene. Microbiology 140: 3337-3348.
10. Bost, S. and D. Belin. 1995. A new genetic selection identifies essential residues in SecG, a component of the Escherichia coli protein export machinery. EMBO J. 14: 4412-4421.
11. Boucher, J.C., J. Martinez-Salazar, M.J. Schurr, M.H. Mudd, and V. Deretic. 1996. Two distinct loci affecting conversion to mucoidy in Pseudomonas aeruginosa in cystic fibrosis encode homologs of the serine protease HtrA. J. Bacteriol. 178: 511-523.
12. Busby, S. and R.H. Ebright. 1994. Promoter structure, promoter recognition, and transcription activation in prokaryotes. Cell 79: 743-746.
13. Clubb, R.T., S.B. Ferguson, C.T. Walsh, and G. Wagner. 1994. Three-dimensional solution structure of Escherichia coli periplasmic cyclophiln. Biochemistry 33: 2761-2772.
14. Cosma, C.L., P.N. Danese, J.H. Carlson, T.J. Silhavy, and W.B. Snyder. 1995. Mutational activation of the Cpx signal transduction pathway of Escherichia coli suppresses the toxicity conferred by certain envelope-associated stresses. Mol. Microbiol. 18: 491-505.
15. E and the Cpx signal transduction systems control the synthesis of periplasmic protein-folding enzymes in Escherichia coli. Genes & Dev. (this issue).
16. Danese, P.N., W.B. Snyder, C.L. Cosma, L.J.B. Davis, and T.J. Silhavy. 1995. The Cpx two-component signal transduction pathway of Escherichia coli regulates transcription of the gene specifying the stress-inducible periplasmic protease, DegP. Genes & Dev. 9: 387-398.
17. E. Mol. Microbiol. (in press).
18. Dong, J.M., S. Iuchi, H.S. Kwan, Z. Lu, and E.C.C. Lin. 1993. The deduced amino acid sequence of the cloned cpxR gene suggests the protein is the cognate regulator for the membrane sensor, CpxA, in a two-component signal transduction system of Escherichia coli. Gene 136: 227-230.
19. Elzer, P.H., R.W. Phillips, M.E. Kovach, K.M. Peterson, and R.M. Roop II. 1994. Characterization and genetic complementation of a Brucella abortus high-temperature-requirement A (htrA) deletion mutant. Infect. Immun. 62: 4135-4139.
20. E subunit of Escherichia coli RNA polymerase: A second alternate σ factor involved in high-temperature gene expression. Genes & Dev. 3: 1462-1471.
21. Govan, J.R. and V. Deretic. 1996. Microbial pathogenesis in cystic fibrosis: Mucoid Pseudomonas aeruginosa and Burkholderia cepacia. Microbiol. Rev. 60: 539-574.
22. Guilhot, C., G. Jander, N.L. Martin, and J. Beckwith. 1995. Evidence that the pathway of disulfide bond formation in Escherichia coli involves interactions between the cysteines of DsbB and DsbA. Proc. Natl. Acad. Sci. 92: 9895-9899.
23. Gupta, S.D., B.T.O. Lee, J. Camakaris, and H.C. Wu. 1995. Identification of cutC and cutF (nlpE) genes involved in copper tolerance in Escherichia coli. J. Bacteriol. 177: 4207-4215.
24. Guzman, L.M., D. Belin, M.J. Carson, and J. Beckwith. 1995. Tight regulation, modulation, and high-level expression by vectors containing the arabinose Pbad promoter. J. Bacteriol. 177: 4121-4130.
25. Hacker, J. and G. Fischer. 1993. Immunophilins: Structure-function relationship and possible role in microbial pathogenicity. Mol. Microbiol. 10: 445-456.
26. Hayano, T., N. Takahashi, S. Kato, N. Kaki, and M. Suzuki. 1991. Two distinct forms of peptidyl-prolyl-cis-trans-isomerase are expressed separately in periplasmic and cytoplasmic compartments of Escherichia coli cells. Biochemistry 30: 3041-3048.
27. Horne, S.M. and K.D. Young. 1995. Escherichia coli and other species of the Enterobacteriaceae encode a protein similar to the family of Mip-like FK506-binding proteins. Arch. Microbiol. 163: 357-365.
28. Iuchi, S. and E.C.C. Lin. 1988. arcA (dye), a global regulatory gene in Escherichia coli mediating repression of enzymes in aerobic pathways. Proc. Natl. Acad. Sci. 85: 1888-1892.
29. Jander, G., N.L. Martin, and J. Beckwith. 1994. Two cysteines in each periplasmic domain of the membrane protein DsbB are required for its function in protein disulfide bond formation. EMBO J. 13: 5121-5127.
30. Johnson, K., I. Charles, G. Dougan, D. Pickard, O. O'Gaora, G. Costa, I. Miller, and C. Hormaeche. 1991. The role of stress-response protein in Salmonella typhimurium virulence. Mol. Microbiol. 5: 401-407.
31. Joung, J., D. Koepp, and A. Hochschild. 1994. Synergistic activation of transcription by bacteriophage lambda cI protein and E. coli cAMP receptor protein. Science 265: 1863-1866.
32. Kamitani, S., Y. Akiyama, and K. Ito. 1992. Identification and characterization of an Escherichia coli gene required for the formation of correctly folded alkaline phosphatase, a periplasmic enzyme. EMBO J. 11: 57-62.
33. Kawamukai, M., H. Matsuda, W. Fujii, R. Utsumi, and T. Komano. 1989. Nucleotide sequences of fic and fic-1 genes involved in cell filamentation induced by cAMP in Escherichia coli. J. Bacteriol. 171: 4525-4529.
34. Kleerebezem, M., M. Heutink, and J. Tommassen. 1995. Characterization of an Escherichia coli rotA mutant, affected in periplasmic peptidyl-prolyl cis/trans isomerase. Mol. Microbiol. 18: 313-320.
35. Lazar, S.W. and R. Kolter. 1996. SurA assists the folding of Escherichia coli outer membrane proteins. J. Bacteriol. 178: 1770-1773.
36. Li, M., H. Moyle, and M. Susskind. 1994. Target of the transcriptional activation function of phage lambda cI protein. Science 263: 75-77.
37. 32-independent mechanism of heat-inducible transcription. Nucleic Acids Res. 16: 10053-10067.
38. Liu, J. and C.T. Walsh. 1990. Peptidyl-prolyl cis-trans-isomerase from Escherichia coli: A periplasmic homolog of cyclophilin that is not inhibited by cyclosporin A. Proc. Natl. Acad. Sci. 87: 4028-4032.
39. Lynch, A.S. and E.C.C. Lin. 1996. Transcriptional control mediated by the ArcA two-component response regulator protein of Escherichia coli: Characterization of DNA binding at target promoters. J. Bacteriol. 178: 6238-6249.
40. Marletta, M.A. 1993. Nitric oxide synthase: Function and mechanism. Adv. Exp. Med. Biol. 338: 281-284.
41. E, an Escherichia coli heat-inducible a-factor, is modulated by expression of outer membrane proteins. Genes & Dev. 7: 2618-2628.
42. Menard, R., C. Dehio, and P.J. Sansonetti. 1996. Bacterial entry into epithelial cells: The paradigm of Shigella. Trends Microbiol 4: 220-226.
43. Missiakas, D., J. Betton, and S. Raina. 1996. New components of protein folding in extracytoplasmic compartments of Escherichia coli SurA, FkpA and Skp/OmpH. Mol. Microbiol. 21: 871-884.
44. Nakayama, S. and H. Watanabe. 1995. Involvement of cpxA, a sensor of a two-component regulatory system, in the pH-dependent regulation of expression of Shigella sonnei virF gene. J. Bacteriol. 177: 5062-5069.
45. Nathan, C.F. and J.B. Hibbs. 1991. Role of nitric oxide synthesis in macrophage antimicrobial activity. Curr. Opin. Immunol. 3: 65-70.
46. Niu, W., Y. Kim, G. Tau, T. Heyduk, and R.H. Ebright. 1996. Transcription activation at class II CAP-dependent promoters: Two interactions between CAP and RNA polymerase. Cell 87: 1123-1134.
47. Norregaard-Madsen, M., B. Mygind, R. Pedersen, P. Valentin-Hansen, and L. Sogaard-Andersen. 1994. The gene encoding the periplasmic cyclophilin homoloque, PPIase A, in Escherichia coli, is expressed from four promoters, three of which are activated by the cAMP-CRP complex and negatively regulated by the CytR repressor. Mol. Microbiol. 14: 989-997.
48. Parkinson, J.S. and E.C. Kofoid. 1992. Communication modules in bacterial signaling proteins. Annu. Rev. Genet. 26: 71-112.
49. Peek, J.A. and R.K. Taylor. 1992. Characterization of a periplasmic thiol:disulfide interchange protein required for the functional maturation of secreted virulence factors of Vibrio cholerae. Proc. Natl. Acad. Sci. 89: 6210-6214.
50. Pogliano, K.J. and J. Beckwith. 1993. The Cs sec mutants of Escherichia coli reflect the cold sensitivity of protein export itself. Genetics 133: 763-773.
51. Rahfeld, J., A. Schierhorn, K. Mann, and G. Fischer. 1994. A novel peptidyl-prolyl cis/trans isomerase from Escherichia coli. FEBS Lett. 343: 65-69.
52. 24) heat shock sigma factor of Escherichia coli. EMBO J. 14: 1043-1055.
53. Rainwater, S. and P. Silverman. 1990. The Cpx proteins of Escherichia coli K-12: Evidence that cpxA, ecfB, ssd, and eup mutations all identify the same gene. J. Bacteriol. 172: 2456-2461.
54. Rietsch, A., D. Belin, N. Martin, and J. Beckwith. 1996. An in vivo pathway for disulfide bond isomerization in Escherichia coli. Proc. Natl. Acad. Sci. 93: 13048-13053.
55. Roof, W.D., S.M. Horne, K.D. Young, and Y. Young. 1994. slyD, a host gene required for ΦX174 lysis, is related to the FK506-binding protein family of peptidyl-prolyl cis-trans isomerases. J. Biol. Chem. 269: 2902-2910.
56. Rouvière, P.E. and C.A. Gross. 1996. SurA, a periplasmic protein with peptidyl-prolyl isomerase activity, participates in the assembly of outer membrane porins. Genes & Dev. 10: 3170-3182.
57. E, in Escherichia coli. EMBO J. 14: 1032-1042.
58. Rudd, K.E., H.J. Sofia, E.V. Koonin, G. Plunkett III, S. Lazar, and P.E. Rouviere. 1995. A new family of peptidyl-prolyl isomerase. Trends Biochem. Sci. 20: 12-14.
59. Schonbrunner, E.R. and F.X. Schmid. 1992. Peptidyl-prolyl cistrans isomerase improves the efficiency of protein disulfide isomerase as a catalyst of protein folding. Proc. Natl. Acad. Sci. 89: 4510-4513.
60. Snyder, W.B., L.J. Davis, P.N. Danese, C.L. Cosma, and T.J. Silhavy. 1995. Overproduction of N1pE, a new outer membrane lipoprotein, suppresses the toxicity of periplasmic LacZ by activation of the Cpx signal transduction pathway. J. Bacteriol. 177: 4216-4223.
61. Strauch, K.L. and J. Beckwith. 1988. An Escherichia coli mutation preventing degradation of abnormal periplasmic proteins. Proc. Natl. Acad. Sci. 85: 1576-1580.
62. Strauch, K.L., K. Johnson, and J. Beckwith. 1989. Characterization of degP, a gene required for proteolysis in the cell envelope and essential for growth of Escherichia coli at high temperature. J. Bacteriol. 171: 2689-2696.
63. Visick, J.E. and S. Clarke. 1995. Repair, refold, recycle: How bacteria can deal with spontaneous and environmental damage to proteins. Mol. Microbiol. 16: 835-845.
64. Watarai, M., T. Tobe, M. Yoshikawa, and C. Sasakawa. 1995. Disulfide oxidoreductase activity of Shigella flexneri is required for release of Ipa proteins and invasion of epithelial cells. Proc. Natl Acad. Sci. 92: 4927-4931.
65. Wulfing, C. and A. Pluckthun. 1994. Protein folding in the periplasm of Escherichia coli. Mol. Microbiol. 12: 685-692.
66. Wulfing, C., J. Lombardero, and A. Pluckthun. 1994. An Escherichia coli protein consisting of a domain homologous to FK506-binding proteins (FKBP) and a new metal binding motif. J. Biol. Chem. 269: 2895-2901.