Hydroxyurea Induces Hydroxyl Radical-Mediated Cell Death in Escherichia coli

Molecular Cell

Volumn 36, Issue 5, 2009, Pages 845-860

  Davies, Bryan W ^a   Kohanski, Michael A ^b,c   Simmons, Lyle A ^a,e   Winkler, Jonathan A ^d   Collins, James J ^b,c   Walker, Graham C ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b Boston University   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Biochemistry   (United States)

^e UNIVERSITY OF MICHIGAN   (United States)

Author keywords

CELLCYCLE; DNA; SYSBIO

Indexed keywords

BACTERIAL PROTEIN; CYTOCHROME C OXIDASE; HYDROXYL RADICAL; HYDROXYUREA; PROTEIN MAZF; PROTEIN RELE; RIBONUCLEOTIDE REDUCTASE; UNCLASSIFIED DRUG;

ARTICLE; CELL DEATH; DNA DAMAGE; DRUG MECHANISM; ESCHERICHIA COLI; GENOMIC INSTABILITY; NONHUMAN; PROTEIN SYNTHESIS; UPREGULATION;

APOPTOSIS; BACTERIAL TOXINS; CELL MEMBRANE; DNA DAMAGE; DNA REPLICATION; DNA-BINDING PROTEINS; ENDORIBONUCLEASES; ENZYME INHIBITORS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENOME, BACTERIAL; HYDROXYUREA; MODELS, BIOLOGICAL; SUPEROXIDES; TIME FACTORS; TRANSCRIPTION, GENETIC;

ESCHERICHIA COLI;

EID: 71149083755     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2009.11.024     Document Type: Article

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