Structural and biological studies on bacterial nitric oxide synthase inhibitors

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 45, 2013, Pages 18127-18131

  Holden, Jeffrey K ^a   Li, Huiying ^a   Jing, Qing ^b   Kang, Soosung ^b   Richo, Jerry ^a   Silverman, Richard B ^b   Poulos, Thomas L ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Antibiotics; Crystallography

Indexed keywords

ANTIINFECTIVE AGENT; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACILLUS SUBTILIS; BACTERIAL GROWTH; BACTERIAL VIABILITY; CRYSTAL STRUCTURE; DRUG STRUCTURE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

ANTIBIOTICS; CRYSTALLOGRAPHY;

ANIMALS; ANTI-BACTERIAL AGENTS; BACILLUS SUBTILIS; CATALYTIC DOMAIN; CLONING, MOLECULAR; CRYSTALLIZATION; HEME; IMIDAZOLES; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; NITRIC OXIDE SYNTHASE; OXIDATIVE STRESS; PROTEIN BINDING; RATS; REGRESSION ANALYSIS;

EID: 84887306037     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1314080110     Document Type: Article

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