-
1
-
-
0036741098
-
A role for local inflammation in the formation of drusen in the aging eye
-
Anderson DH, Mullins RF, Hageman GS, Johnson LV (2002) A role for local inflammation in the formation of drusen in the aging eye. Am J Ophthalmol 134(3):411-431
-
(2002)
Am J Ophthalmol
, vol.134
, Issue.3
, pp. 411-431
-
-
Anderson, D.H.1
Mullins, R.F.2
Hageman, G.S.3
Johnson, L.V.4
-
2
-
-
0034832029
-
An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration
-
Hageman GS, Luthert PJ, Victor Chong NH, Johnson LV, Anderson DH, Mullins RF (2001) An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration. Prog Retin Eye Res 20(6):705-732
-
(2001)
Prog Retin Eye Res
, vol.20
, Issue.6
, pp. 705-732
-
-
Hageman, G.S.1
Luthert, P.J.2
Victor Chong, N.H.3
Johnson, L.V.4
Anderson, D.H.5
Mullins, R.F.6
-
3
-
-
0035699547
-
Complement activation and inflammatory processes in Drusen formation and age related macular degeneration
-
Johnson LV, Leitner WP, Staples MK, Anderson DH (2001) Complement activation and inflammatory processes in Drusen formation and age related macular degeneration. Exp Eye Res 73(6):887-896
-
(2001)
Exp Eye Res
, vol.73
, Issue.6
, pp. 887-896
-
-
Johnson, L.V.1
Leitner, W.P.2
Staples, M.K.3
Anderson, D.H.4
-
5
-
-
77249147331
-
The pivotal role of the complement system in aging and age-related macular degeneration: Hypothesis re-visited
-
Anderson DH, Radeke MJ, Gallo NB, Chapin EA, Johnson PT, Curletti CR, Hancox LS, Hu J, Ebright JN, Malek G, Hauser MA, Bowes Rickman C, Bok D, Hageman GS, Johnson LV (2010) The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited. Prog Retin Eye Res 29(2):95-112
-
(2010)
Prog Retin Eye Res
, vol.29
, Issue.2
, pp. 95-112
-
-
Anderson, D.H.1
Radeke, M.J.2
Gallo, N.B.3
Chapin, E.A.4
Johnson, P.T.5
Curletti, C.R.6
Hancox, L.S.7
Hu, J.8
Ebright, J.N.9
Malek, G.10
Hauser, M.A.11
Bowes Rickman, C.12
Bok, D.13
Hageman, G.S.14
Johnson, L.V.15
-
6
-
-
31144460785
-
The central role of the alternative complement pathway in human disease
-
Thurman JM, Holers VM (2006) The central role of the alternative complement pathway in human disease. J Immunol 176(3):1305-1310
-
(2006)
J Immunol
, vol.176
, Issue.3
, pp. 1305-1310
-
-
Thurman, J.M.1
Holers, V.M.2
-
7
-
-
33751243644
-
Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid
-
Johnson PT, Betts KE, Radeke MJ, Hageman GS, Anderson DH, Johnson LV (2006) Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid. Proc Natl Acad Sci U S A 103(46):17456-17461
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, Issue.46
, pp. 17456-17461
-
-
Johnson, P.T.1
Betts, K.E.2
Radeke, M.J.3
Hageman, G.S.4
Anderson, D.H.5
Johnson, L.V.6
-
8
-
-
0036699540
-
Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H
-
Pickering MC, Cook HT, Warren J, Bygrave AE, Moss J, Walport MJ, Botto M (2002) Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H. Nat Genet 31(4):424-428
-
(2002)
Nat Genet
, vol.31
, Issue.4
, pp. 424-428
-
-
Pickering, M.C.1
Cook, H.T.2
Warren, J.3
Bygrave, A.E.4
Moss, J.5
Walport, M.J.6
Botto, M.7
-
9
-
-
36749004311
-
Complement factor H deficiency in aged mice causes retinal abnormalities and visual dysfunction
-
Coffey PJ, Gias C, McDermott CJ, Lundh P, Pickering MC, Sethi C, Bird A, Fitzke FW, Maass A, Chen LL, Holder GE, Luthert PJ, Salt TE, Moss SE, Greenwood J (2007) Complement factor H deficiency in aged mice causes retinal abnormalities and visual dysfunction. Proc Natl Acad Sci U S A 104(42):16651-16656
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, Issue.42
, pp. 16651-16656
-
-
Coffey, P.J.1
Gias, C.2
McDermott, C.J.3
Lundh, P.4
Pickering, M.C.5
Sethi, C.6
Bird, A.7
Fitzke, F.W.8
Maass, A.9
Chen, L.L.10
Holder, G.E.11
Luthert, P.J.12
Salt, T.E.13
Moss, S.E.14
Greenwood, J.15
-
10
-
-
67649969175
-
Complement factor h is critical in the maintenance of retinal perfusion
-
Lundh von Leithner P, Kam JH, Bainbridge J, Catchpole I, Gough G, Coffey P, Jeffery G (2009) Complement factor h is critical in the maintenance of retinal perfusion. Am J Pathol 175(1):412-421
-
(2009)
Am J Pathol
, vol.175
, Issue.1
, pp. 412-421
-
-
Lundh von Leithner, P.1
Kam, J.H.2
Bainbridge, J.3
Catchpole, I.4
Gough, G.5
Coffey, P.6
Jeffery, G.7
-
11
-
-
0027313975
-
Mouse Crry/p65 is a regulator of the alternative pathway of complement activation
-
Foley S, Li B, Dehoff M, Molina H, Holers VM (1993) Mouse Crry/p65 is a regulator of the alternative pathway of complement activation. Eur J Immunol 23(6):1381-1384
-
(1993)
Eur J Immunol
, vol.23
, Issue.6
, pp. 1381-1384
-
-
Foley, S.1
Li, B.2
Dehoff, M.3
Molina, H.4
Holers, V.M.5
-
12
-
-
0032487432
-
Transgenic mice overexpressing the complement inhibitor crry as a soluble protein are protected from antibody-induced glomerular injury
-
Quigg RJ, He C, Lim A, Berthiaume D, Alexander JJ, Kraus D, Holers VM (1998) Transgenic mice overexpressing the complement inhibitor crry as a soluble protein are protected from antibody-induced glomerular injury. J Exp Med 188(7):1321-1331
-
(1998)
J Exp Med
, vol.188
, Issue.7
, pp. 1321-1331
-
-
Quigg, R.J.1
He, C.2
Lim, A.3
Berthiaume, D.4
Alexander, J.J.5
Kraus, D.6
Holers, V.M.7
-
13
-
-
0036679142
-
Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice
-
Wyss-Coray T, Yan F, Lin AH, Lambris JD, Alexander JJ, Quigg RJ, Masliah E (2002) Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice. Proc Natl Acad Sci U S A 99(16):10837-10842
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, Issue.16
, pp. 10837-10842
-
-
Wyss-Coray, T.1
Yan, F.2
Lin, A.H.3
Lambris, J.D.4
Alexander, J.J.5
Quigg, R.J.6
Masliah, E.7
-
14
-
-
38749112528
-
Targeting age-related macular degeneration with Alzheimer's disease based immunotherapies: Anti-amyloid-beta antibody attenuates pathologies in an age-related macular degeneration mouse model
-
Ding JD, Lin J, Mace BE, Herrmann R, Sullivan P, Bowes Rickman C (2008) Targeting age-related macular degeneration with Alzheimer's disease based immunotherapies: anti-amyloid-beta antibody attenuates pathologies in an age-related macular degeneration mouse model. Vision Res 48(3):339-345
-
(2008)
Vision Res
, vol.48
, Issue.3
, pp. 339-345
-
-
Ding, J.D.1
Lin, J.2
Mace, B.E.3
Herrmann, R.4
Sullivan, P.5
Bowes Rickman, C.6
-
15
-
-
0037015020
-
The Alzheimer's A beta -peptide is deposited at sites of complement activation in pathologic deposits associated with aging and age-related macular degeneration
-
Johnson LV, Leitner WP, Rivest AJ, Staples MK, Radeke MJ, Anderson DH (2002) The Alzheimer's A beta -peptide is deposited at sites of complement activation in pathologic deposits associated with aging and age-related macular degeneration. Proc Natl Acad Sci U S A 99(18):11830-11835
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, Issue.18
, pp. 11830-11835
-
-
Johnson, L.V.1
Leitner, W.P.2
Rivest, A.J.3
Staples, M.K.4
Radeke, M.J.5
Anderson, D.H.6
-
17
-
-
79955050748
-
Transgenic mice expressing variants of complement factor H develop AMDlike retinal findings
-
Ufret-Vincenty RL, Aredo B, Liu X, McMahon A, Chen PW, Sun H, Niederkorn JY, Kedzierski W (2010) Transgenic mice expressing variants of complement factor H develop AMDlike retinal findings. Invest Ophthal Vis Sci 51(11):5878-5887
-
(2010)
Invest Ophthal Vis Sci
, vol.51
, Issue.11
, pp. 5878-5887
-
-
Ufret-Vincenty, R.L.1
Aredo, B.2
Liu, X.3
McMahon, A.4
Chen, P.W.5
Sun, H.6
Niederkorn, J.Y.7
Kedzierski, W.8
-
18
-
-
23844463473
-
Apolipoprotein E allele-dependent pathogenesis: A model for age-related retinal degeneration
-
Malek G, Johnson LV, Mace BE, Saloupis P, Schmechel DE, Rickman DW, Toth CA, Sullivan PM, Bowes Rickman C (2005) Apolipoprotein E allele-dependent pathogenesis: a model for age-related retinal degeneration. Proc Natl Acad Sci U S A 102(33):11900-11905
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, Issue.33
, pp. 11900-11905
-
-
Malek, G.1
Johnson, L.V.2
Mace, B.E.3
Saloupis, P.4
Schmechel, D.E.5
Rickman, D.W.6
Toth, C.A.7
Sullivan, P.M.8
Bowes Rickman, C.9
-
19
-
-
79961005068
-
Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration
-
Ding JD, Johnson LV, Herrmann R, Farsiu S, Smith SG, Groelle M, Mace BE, Sullivan P, Jamison JA, Kelly U, Harrabi O, Bollini SS, Dilley J, Kobayashi D, Kuang B, Li W, Pons J, Lin JC, Rickman CB (2011) Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration. Proc Natl Acad Sci U S A 108(28):E279-E287
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.28
, pp. E279-E287
-
-
Ding, J.D.1
Johnson, L.V.2
Herrmann, R.3
Farsiu, S.4
Smith, S.G.5
Groelle, M.6
Mace, B.E.7
Sullivan, P.8
Jamison, J.A.9
Kelly, U.10
Harrabi, O.11
Bollini, S.S.12
Dilley, J.13
Kobayashi, D.14
Kuang, B.15
Li, W.16
Pons, J.17
Lin, J.C.18
Rickman, C.B.19
|