Transgenic mice overexpressing the complement inhibitor Crry as a soluble protein are protected from antibody-induced glomerular injury

Journal of Experimental Medicine

Volumn 188, Issue 7, 1998, Pages 1321-1331

  Quigg, Richard J ^a   He, Chun ^a   Lim, Alice ^a   Berthiaume, Dawn ^b   Alexander, Jessy J ^a   Kraus, Damian ^b   Holers, V Michael ^b  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

Anti glomerular basement membrane disease; Complement; Complement inactivators; Crry; Mice, transgenic

Indexed keywords

BASEMENT MEMBRANE ANTIBODY; COMPLEMENT; COMPLEMENT INHIBITOR; PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPLEMENT ACTIVATION; COMPLEMENT INHIBITION; CONTROLLED STUDY; FEMALE; GLOMERULUS BASEMENT MEMBRANE; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOPATHOGENESIS; MALE; NEPHRITIS; NONHUMAN; PRIORITY JOURNAL; PROTEINURIA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE;

ANIMALS; ANTIBODIES; COMPLEMENT ACTIVATION; COMPLEMENT INACTIVATOR PROTEINS; COMPLEMENT SYSTEM PROTEINS; KIDNEY GLOMERULUS; MICE; MICE, TRANSGENIC; RECEPTORS, COMPLEMENT; SOLUBILITY;

EID: 0032487432     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.188.7.1321     Document Type: Article

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