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Volumn 35, Issue 6, 2014, Pages 6073-6082

SUZ12 is involved in progression of non-small cell lung cancer by promoting cell proliferation and metastasis

Author keywords

Metastasis; NSCLC; Proliferation; SUZ12

Indexed keywords

POLYCOMB REPRESSIVE COMPLEX 2; PROTEIN KINASE; RHO ASSOCIATED COILED COIL CONTAINING PROTEIN KINASE 1; ROUNDABOUT HOMOLOG 1 PROTEIN; SMALL INTERFERING RNA; SUPPRESSOR OF ZESTE 12 PROTEIN; TRANSCRIPTION FACTOR E2F1; TUMOR PROTEIN; UNCLASSIFIED DRUG;

EID: 84904726416     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-014-1804-5     Document Type: Article
Times cited : (43)

References (51)
  • 2
    • 84872967522 scopus 로고    scopus 로고
    • Cancer statistics, 2013
    • doi:10.3322/caac.21166
    • Siegel R, Naishadham D, Jemal A. Cancer statistics, 2013. CA Cancer J Clin. 2013;63(1):11-30. doi:10.3322/caac.21166.
    • (2013) CA Cancer J Clin , vol.63 , Issue.1 , pp. 11-30
    • Siegel, R.1    Naishadham, D.2    Jemal, A.3
  • 3
    • 84863272656 scopus 로고    scopus 로고
    • Clinical trials and biomarker research on lung cancer in China
    • doi:10.1517/14728222.2011.630663
    • Wu YL, Zhou Q. Clinical trials and biomarker research on lung cancer in China. Expert Opin Ther Targets. 2012;16 Suppl 1:S45-50. doi:10.1517/14728222. 2011.630663.
    • (2012) Expert Opin Ther Targets , vol.16 , Issue.SUPPL. 1
    • Wu, Y.L.1    Zhou, Q.2
  • 4
    • 84888767796 scopus 로고    scopus 로고
    • Integrated molecular portrait of non-small cell lung cancers
    • doi:10.1186/1755-8794-6-53
    • Lazar V, Suo C, Orear C, van den Oord J, Balogh Z, Guegan J, et al. Integrated molecular portrait of non-small cell lung cancers. BMC Med Genomics. 2013;6:53. doi:10.1186/1755-8794-6-53.
    • (2013) BMC Med Genomics , vol.6 , pp. 53
    • Lazar, V.1    Suo, C.2    Orear, C.3    Van Den Oord, J.4    Balogh, Z.5    Guegan, J.6
  • 6
    • 52649131951 scopus 로고    scopus 로고
    • Lung cancer
    • doi:10.1056/NEJMra0802714
    • Herbst RS, Heymach JV, Lippman SM. Lung cancer. N Engl J Med. 2008;359(13):1367-80. doi:10.1056/NEJMra0802714.
    • (2008) N Engl J Med , vol.359 , Issue.13 , pp. 1367-1380
    • Herbst, R.S.1    Heymach, J.V.2    Lippman, S.M.3
  • 7
    • 80051965827 scopus 로고    scopus 로고
    • Relative abundance of EGFR mutations predicts benefit from gefitinib treatment for advanced non-small-cell lung cancer
    • doi:10.1200/jco.2010.33.3757
    • Zhou Q, Zhang XC, Chen ZH, Yin XL, Yang JJ, Xu CR, et al. Relative abundance of EGFR mutations predicts benefit from gefitinib treatment for advanced non-small-cell lung cancer. J Clin Oncol Off J Am Soc Clin Oncol. 2011;29(24):3316-21. doi:10.1200/jco.2010.33.3757.
    • (2011) J Clin Oncol off J Am Soc Clin Oncol , vol.29 , Issue.24 , pp. 3316-3321
    • Zhou, Q.1    Zhang, X.C.2    Chen, Z.H.3    Yin, X.L.4    Yang, J.J.5    Xu, C.R.6
  • 9
    • 0036830642 scopus 로고    scopus 로고
    • Role of histone H3 lysine 27 methylation in polycomb-group silencing
    • DOI 10.1126/science.1076997
    • Cao R, Wang L, Wang H, Xia L, Erdjument-Bromage H, Tempst P, et al. Role of histone H3 lysine 27 methylation in Polycomb-group silencing. Science (New York, NY). 2002;298(5595):1039-43. doi:10.1126/science.1076997. (Pubitemid 35247314)
    • (2002) Science , vol.298 , Issue.5595 , pp. 1039-1043
    • Cao, R.1    Wang, L.2    Wang, H.3    Xia, L.4    Erdjument-Bromage, H.5    Tempst, P.6    Jones, R.S.7    Zhang, Y.8
  • 11
    • 8144230178 scopus 로고    scopus 로고
    • Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity
    • DOI 10.1038/sj.emboj.7600402
    • Pasini D, Bracken AP, Jensen MR, Lazzerini Denchi E, Helin K. Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity. EMBO J. 2004;23(20):4061-71. doi:10.1038/sj.emboj.7600402. (Pubitemid 39472427)
    • (2004) EMBO Journal , vol.23 , Issue.20 , pp. 4061-4071
    • Pasini, D.1    Bracken, A.P.2    Jensen, M.R.3    Denchi, E.L.4    Helin, K.5
  • 13
    • 47949125993 scopus 로고    scopus 로고
    • Polycomb complex 2 is required for E-cadherin repression by the Snail1 transcription factor
    • doi:10.1128/mcb.00323-08
    • Herranz N, Pasini D, Diaz VM, Franci C, Gutierrez A, Dave N, et al. Polycomb complex 2 is required for E-cadherin repression by the Snail1 transcription factor. Mol Cell Biol. 2008;28(15):4772-81. doi:10.1128/mcb.00323- 08.
    • (2008) Mol Cell Biol , vol.28 , Issue.15 , pp. 4772-4781
    • Herranz, N.1    Pasini, D.2    Diaz, V.M.3    Franci, C.4    Gutierrez, A.5    Dave, N.6
  • 14
    • 77956547097 scopus 로고    scopus 로고
    • Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells
    • doi:10.1016/j.molcel.2010.08.013
    • Iliopoulos D, Lindahl-Allen M, Polytarchou C, Hirsch HA, Tsichlis PN, Struhl K. Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells. Mol Cell. 2010;39(5):761-72. doi:10.1016/j.molcel.2010.08.013.
    • (2010) Mol Cell , vol.39 , Issue.5 , pp. 761-772
    • Iliopoulos, D.1    Lindahl-Allen, M.2    Polytarchou, C.3    Hirsch, H.A.4    Tsichlis, P.N.5    Struhl, K.6
  • 16
    • 33644822360 scopus 로고    scopus 로고
    • EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast
    • DOI 10.1200/JCO.2005.01.5180
    • Bachmann IM, Halvorsen OJ, Collett K, Stefansson IM, Straume O, Haukaas SA, et al. EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast. J Clin Oncol Off J Am Soc Clin Oncol. 2006;24(2):268-73. doi:10.1200/jco.2005.01.5180. (Pubitemid 46622055)
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.2 , pp. 268-273
    • Bachmann, I.M.1    Halvorsen, O.J.2    Collett, K.3    Stefansson, I.M.4    Straume, O.5    Haukaas, S.A.6    Salvesen, H.B.7    Otte, A.P.8    Akslen, L.A.9
  • 17
    • 34047229950 scopus 로고    scopus 로고
    • EZH2 promotes proliferation and invasiveness of prostate cancer cells
    • DOI 10.1002/pros.20550
    • Bryant RJ, Cross NA, Eaton CL, Hamdy FC, Cunliffe VT. EZH2 promotes proliferation and invasiveness of prostate cancer cells. Prostate. 2007;67(5):547-56. doi:10.1002/pros.20550. (Pubitemid 46536947)
    • (2007) Prostate , vol.67 , Issue.5 , pp. 547-556
    • Bryant, R.J.1    Cross, N.A.2    Eaton, C.L.3    Hamdy, F.C.4    Cunliffe, V.T.5
  • 19
    • 33646596977 scopus 로고    scopus 로고
    • The gene for polycomb group protein enhancer of zeste homolog 2 (EZH2) is amplified in late-stage prostate cancer
    • DOI 10.1002/gcc.20327
    • Saramaki OR, Tammela TL, Martikainen PM, Vessella RL, Visakorpi T. The gene for polycomb group protein enhancer of zeste homolog 2 (EZH2) is amplified in late-stage prostate cancer. Genes Chromosom Cancer. 2006;45(7):639-45. doi:10.1002/gcc.20327. (Pubitemid 43727151)
    • (2006) Genes Chromosomes and Cancer , vol.45 , Issue.7 , pp. 639-645
    • Saramaki, O.R.1    Tammela, T.L.J.2    Martikainen, P.M.3    Vessella, R.L.4    Visakorpi, T.5
  • 20
    • 18644382388 scopus 로고    scopus 로고
    • The polycomb group protein EZH2 is involved in progression of prostate cancer
    • doi:10.1038/nature01075
    • Varambally S, Dhanasekaran SM, Zhou M, Barrette TR, Kumar-Sinha C, Sanda MG, et al. The polycomb group protein EZH2 is involved in progression of prostate cancer. Nature. 2002;419(6907):624-9. doi:10.1038/nature01075.
    • (2002) Nature , vol.419 , Issue.6907 , pp. 624-629
    • Varambally, S.1    Dhanasekaran, S.M.2    Zhou, M.3    Barrette, T.R.4    Kumar-Sinha, C.5    Sanda, M.G.6
  • 21
    • 84869225502 scopus 로고    scopus 로고
    • SUZ12 promotes human epithelial ovarian cancer by suppressing apoptosis via silencing HRK
    • doi:10.1158/1541-7786.mcr-12-0335
    • Li H, Cai Q, Wu H, Vathipadiekal V, Dobbin ZC, Li T, et al. SUZ12 promotes human epithelial ovarian cancer by suppressing apoptosis via silencing HRK. Mol Cancer Res. 2012;10(11):1462-72. doi:10.1158/1541-7786.mcr-12-0335.
    • (2012) Mol Cancer Res , vol.10 , Issue.11 , pp. 1462-1472
    • Li, H.1    Cai, Q.2    Wu, H.3    Vathipadiekal, V.4    Dobbin, Z.C.5    Li, T.6
  • 22
    • 77957256995 scopus 로고    scopus 로고
    • Deregulated expression of the polycomb-group protein SUZ12 target genes characterizes mantle cell lymphoma
    • doi:10.2353/ajpath.2010.090769
    • Martin-Perez D, Sanchez E, Maestre L, Suela J, Vargiu P, Di Lisio L, et al. Deregulated expression of the polycomb-group protein SUZ12 target genes characterizes mantle cell lymphoma. Am J Pathol. 2010;177(2):930-42. doi:10.2353/ajpath.2010.090769.
    • (2010) Am J Pathol , vol.177 , Issue.2 , pp. 930-942
    • Martin-Perez, D.1    Sanchez, E.2    Maestre, L.3    Suela, J.4    Vargiu, P.5    Di Lisio, L.6
  • 23
    • 37349070024 scopus 로고    scopus 로고
    • An E2F1-Dependent Gene Expression Program that Determines the Balance between Proliferation and Cell Death
    • DOI 10.1016/j.ccr.2007.11.031, PII S1535610807003704
    • Hallstrom TC, Mori S, Nevins JR. An E2F1-dependent gene expression program that determines the balance between proliferation and cell death. Cancer cell. 2008;13(1):11-22. doi:10.1016/j.ccr.2007.11.031. (Pubitemid 350309738)
    • (2008) Cancer Cell , vol.13 , Issue.1 , pp. 11-22
    • Hallstrom, T.C.1    Mori, S.2    Nevins, J.R.3
  • 24
    • 0028909272 scopus 로고
    • Amplification of the E2F1 transcription factor gene in the HEL erythroleukemia cell line
    • Saito M, Helin K, Valentine MB, Griffith BB, Willman CL, Harlow E, et al. Amplification of the E2F1 transcription factor gene in the HEL erythroleukemia cell line. Genomics. 1995;25(1):130-8.
    • (1995) Genomics , vol.25 , Issue.1 , pp. 130-138
    • Saito, M.1    Helin, K.2    Valentine, M.B.3    Griffith, B.B.4    Willman, C.L.5    Harlow, E.6
  • 31
    • 0034009592 scopus 로고    scopus 로고
    • Frequent disruption of the RB1 pathway in diffuse large B cell lymphoma: Prognostic significance of E2F-1 and p16(INK4A)
    • Moller MB, Kania PW, Ino Y, Gerdes AM, Nielsen O, Louis DN, et al. Frequent disruption of the RB1 pathway in diffuse large B cell lymphoma: prognostic significance of E2F-1 and p16INK4A. Leukemia. 2000;14(5):898-904. (Pubitemid 30235069)
    • (2000) Leukemia , vol.14 , Issue.5 , pp. 898-904
    • Moller, M.B.1    Kania, P.W.2    Ino, Y.3    Gerdes, A.-M.4    Nielsen, O.5    Louis, D.N.6    Skjodt, K.7    Pedersen, N.T.8
  • 33
    • 0036773453 scopus 로고    scopus 로고
    • Immunohistochemical expression of cyclin, D1, E2F-1, and Ki-67 in benign and malignant thyroid lesions
    • DOI 10.1002/path.1185
    • Saiz AD, Olvera M, Rezk S, Florentine BA, McCourty A, Brynes RK. Immunohistochemical expression of cyclin D1, E2F-1, and Ki-67 in benign and malignant thyroid lesions. J Pathol. 2002;198(2):157-62. doi:10.1002/path.1185. (Pubitemid 35243873)
    • (2002) Journal of Pathology , vol.198 , Issue.2 , pp. 157-162
    • Saiz, A.D.1    Olvera, M.2    Rezk, S.3    Florentine, B.A.4    McCourty, A.5    Brynes, R.K.6
  • 34
    • 37249080638 scopus 로고    scopus 로고
    • E2F1 overexpression correlates with thymidylate synthase and survivin gene expressions and tumor proliferation in non-small-cell lung cancer
    • DOI 10.1158/1078-0432.CCR-07-1539
    • Huang CL, Liu D, Nakano J, Yokomise H, Ueno M, Kadota K, et al. E2F1 overexpression correlates with thymidylate synthase and survivin gene expressions and tumor proliferation in non small-cell lung cancer. Clin Cancer Res Off J Am Assoc Cancer Res. 2007;13(23):6938-46. doi:10.1158/1078-0432.ccr- 07-1539. (Pubitemid 350276873)
    • (2007) Clinical Cancer Research , vol.13 , Issue.23 , pp. 6938-6946
    • Huang, C.-L.1    Liu, D.2    Nakano, J.3    Yokomise, H.4    Ueno, M.5    Kadota, K.6    Wada, H.7
  • 35
    • 84892930021 scopus 로고    scopus 로고
    • Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells
    • doi:10.1073/pnas.1321510111
    • Gilkes DM, Xiang L, Lee SJ, Chaturvedi P, Hubbi ME, Wirtz D, et al. Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells. Proc Natl Acad Sci U S A. 2014;111(3):E384-93. doi:10.1073/pnas.1321510111.
    • (2014) Proc Natl Acad Sci U S A , vol.111 , Issue.3
    • Gilkes, D.M.1    Xiang, L.2    Lee, S.J.3    Chaturvedi, P.4    Hubbi, M.E.5    Wirtz, D.6
  • 36
    • 84904739505 scopus 로고    scopus 로고
    • MicroRNA 135a Suppresses lymph node metastasis through downregulation of ROCK1 in early gastric cancer
    • doi:10.1371/journal.pone.0085205
    • Shin JY, Kim YI, Cho SJ, Lee MK, Kook MC, Lee JH, et al. MicroRNA 135a Suppresses lymph node metastasis through downregulation of ROCK1 in early gastric cancer. PloS One. 2014;9(1):e85205. doi:10.1371/journal.pone.0085205.
    • (2014) PloS One , vol.9 , Issue.1
    • Shin, J.Y.1    Kim, Y.I.2    Cho, S.J.3    Lee, M.K.4    Kook, M.C.5    Lee, J.H.6
  • 37
    • 84893727497 scopus 로고    scopus 로고
    • The effect of ROCK-1 activity change on the adhesive and invasive ability of Y79 retinoblastoma cells
    • doi:10.1186/1471-2407-14-89
    • Wang J, Liu XH, Yang ZJ, Xie B, Zhong YS. The effect of ROCK-1 activity change on the adhesive and invasive ability of Y79 retinoblastoma cells. BMC Cancer. 2014;14(1):89. doi:10.1186/1471-2407-14-89.
    • (2014) BMC Cancer , vol.14 , Issue.1 , pp. 89
    • Wang, J.1    Liu, X.H.2    Yang, Z.J.3    Xie, B.4    Zhong, Y.S.5
  • 38
    • 84888988014 scopus 로고    scopus 로고
    • ROCK has a crucial role in regulating prostate tumor growth through interaction with c-Myc
    • doi:10.1038/onc.2013.505
    • Zhang C, Zhang S, Zhang Z, He J, Xu Y, Liu S. ROCK has a crucial role in regulating prostate tumor growth through interaction with c-Myc. Oncogene. 2013. doi:10.1038/onc.2013.505.
    • (2013) Oncogene
    • Zhang, C.1    Zhang, S.2    Zhang, Z.3    He, J.4    Xu, Y.5    Liu, S.6
  • 39
    • 73849126315 scopus 로고    scopus 로고
    • Rho-kinase inhibitors as therapeutics: From pan inhibition to isoform selectivity
    • doi:10.1007/s00018-009-0189-x
    • Hahmann C, Schroeter T. Rho-kinase inhibitors as therapeutics: from pan inhibition to isoform selectivity. Cell Mol Life Sci. 2010;67(2):171-7. doi:10.1007/s00018-009-0189-x.
    • (2010) Cell Mol Life Sci , vol.67 , Issue.2 , pp. 171-177
    • Hahmann, C.1    Schroeter, T.2
  • 40
    • 54849186600 scopus 로고    scopus 로고
    • The expression and prognostic value of ROCK I and ROCK II and their role in human breast cancer
    • Lane J, Martin TA, Watkins G, Mansel RE, Jiang WG. The expression and prognostic value of ROCK I and ROCK II and their role in human breast cancer. Int J Oncol. 2008;33(3):585-93.
    • (2008) Int J Oncol , vol.33 , Issue.3 , pp. 585-593
    • Lane, J.1    Martin, T.A.2    Watkins, G.3    Mansel, R.E.4    Jiang, W.G.5
  • 41
    • 33847333362 scopus 로고    scopus 로고
    • Hyaluronan stimulates transformation of androgen-independent prostate cancer
    • DOI 10.1093/carcin/bgl134
    • Lin SL, Chang D, Ying SY. Hyaluronan stimulates transformation of androgen-independent prostate cancer. Carcinogenesis. 2007;28(2):310-20. doi:10.1093/carcin/bgl134. (Pubitemid 46321846)
    • (2007) Carcinogenesis , vol.28 , Issue.2 , pp. 310-320
    • Lin, S.-L.1    Chang, D.2    Ying, S.-Y.3
  • 42
    • 72249097073 scopus 로고    scopus 로고
    • Inhibition of rho-associated kinase signaling prevents breast cancer metastasis to human bone
    • doi:10.1158/0008-5472.can-09-1541
    • Liu S, Goldstein RH, Scepansky EM, Rosenblatt M. Inhibition of rho-associated kinase signaling prevents breast cancer metastasis to human bone. Cancer Res. 2009;69(22):8742-51. doi:10.1158/0008-5472.can-09-1541.
    • (2009) Cancer Res , vol.69 , Issue.22 , pp. 8742-8751
    • Liu, S.1    Goldstein, R.H.2    Scepansky, E.M.3    Rosenblatt, M.4
  • 43
    • 77951880868 scopus 로고    scopus 로고
    • Activating ROCK1 somatic mutations in human cancer
    • doi:10.1038/onc.2010.3
    • Lochhead PA, Wickman G, Mezna M, Olson MF. Activating ROCK1 somatic mutations in human cancer. Oncogene. 2010;29(17):2591-8. doi:10.1038/onc.2010.3.
    • (2010) Oncogene , vol.29 , Issue.17 , pp. 2591-2598
    • Lochhead, P.A.1    Wickman, G.2    Mezna, M.3    Olson, M.F.4
  • 44
    • 68549122708 scopus 로고    scopus 로고
    • Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion
    • doi:10.1007/s10555-008-9170-7
    • Narumiya S, Tanji M, Ishizaki T. Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion. Cancer Metastasis Rev. 2009;28(1-2):65-76. doi:10.1007/s10555-008-9170-7.
    • (2009) Cancer Metastasis Rev , vol.28 , Issue.1-2 , pp. 65-76
    • Narumiya, S.1    Tanji, M.2    Ishizaki, T.3
  • 45
    • 10744221211 scopus 로고    scopus 로고
    • Neuronal repellent Slit2 inhibits dendritic cell migration and the development of immune responses
    • Guan H, Zu G, Xie Y, Tang H, Johnson M, Xu X, et al. Neuronal repellent Slit2 inhibits dendritic cell migration and the development of immune responses. J Immunol (Baltimore, Md : 1950). 2003;171(12):6519-26.
    • (2003) J Immunol (Baltimore, Md: 1950) , vol.171 , Issue.12 , pp. 6519-6526
    • Guan, H.1    Zu, G.2    Xie, Y.3    Tang, H.4    Johnson, M.5    Xu, X.6
  • 46
    • 34548440745 scopus 로고    scopus 로고
    • Regulation of axon guidance by slit and netrin signaling in the drosophila ventral nerve cord
    • DOI 10.1534/genetics.107.075085
    • Bhat KM, Gaziova I, Krishnan S. Regulation of axon guidance by slit and netrin signaling in the Drosophila ventral nerve cord. Genetics. 2007;176(4):2235-46. doi:10.1534/genetics.107.075085. (Pubitemid 47360656)
    • (2007) Genetics , vol.176 , Issue.4 , pp. 2235-2246
    • Bhat, K.M.1    Gaziova, I.2    Krishnan, S.3
  • 47
    • 33751162427 scopus 로고    scopus 로고
    • Regulation of commissural axon pathfinding by slit and its Robo receptors
    • doi:10.1146/annurev.cellbio.21.090704.151234
    • Dickson BJ, Gilestro GF. Regulation of commissural axon pathfinding by slit and its Robo receptors. Annu Rev Cell Dev Biol. 2006;22:651-75. doi:10.1146/annurev.cellbio.21.090704.151234.
    • (2006) Annu Rev Cell Dev Biol , vol.22 , pp. 651-675
    • Dickson, B.J.1    Gilestro, G.F.2
  • 48
    • 0032559219 scopus 로고    scopus 로고
    • Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors
    • DOI 10.1016/S0092-8674(00)80915-0
    • Kidd T, Brose K, Mitchell KJ, Fetter RD, Tessier-Lavigne M, Goodman CS, et al. Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors. Cell. 1998;92(2):205-15. (Pubitemid 28073044)
    • (1998) Cell , vol.92 , Issue.2 , pp. 205-215
    • Kidd, T.1    Brose, K.2    Mitchell, K.J.3    Fetter, R.D.4    Tessier-Lavigne, M.5    Goodman, C.S.6    Tear, G.7
  • 49
    • 34447277390 scopus 로고    scopus 로고
    • Deletions in chromosome 4 differentially associated with the development of cervical cancer: Evidence of slit2 as a candidate tumor suppressor gene
    • DOI 10.1007/s00439-007-0375-6
    • Singh RK, Indra D, Mitra S, Mondal RK, Basu PS, Roy A, et al. Deletions in chromosome 4 differentially associated with the development of cervical cancer: evidence of slit2 as a candidate tumor suppressor gene. Hum Genet. 2007;122(1):71-81. doi:10.1007/s00439-007-0375-6. (Pubitemid 47040575)
    • (2007) Human Genetics , vol.122 , Issue.1 , pp. 71-81
    • Singh, R.K.1    Indra, D.2    Mitra, S.3    Mondal, R.K.4    Basu, P.S.5    Roy, A.6    Roychowdhury, S.7    Panda, C.K.8
  • 50
    • 33745493625 scopus 로고    scopus 로고
    • Promoter hypermethylation-mediated inactivation of multiple Slit-Robo pathway genes in cervical cancer progression
    • doi:10.1186/1476-4598-5-16
    • Narayan G, Goparaju C, Arias-Pulido H, Kaufmann AM, Schneider A, Durst M, et al. Promoter hypermethylation-mediated inactivation of multiple Slit-Robo pathway genes in cervical cancer progression. Mol Cancer. 2006;5:16. doi:10.1186/1476-4598-5-16.
    • (2006) Mol Cancer , vol.5 , pp. 16
    • Narayan, G.1    Goparaju, C.2    Arias-Pulido, H.3    Kaufmann, A.M.4    Schneider, A.5    Durst, M.6
  • 51
    • 55549115695 scopus 로고    scopus 로고
    • Slit-2 induces a tumor-suppressive effect by regulating beta-catenin in breast cancer cells
    • doi:10.1074/jbc.M800679200
    • Prasad A, Paruchuri V, Preet A, Latif F, Ganju RK. Slit-2 induces a tumor-suppressive effect by regulating beta-catenin in breast cancer cells. J Biol Chem. 2008;283(39):26624-33. doi:10.1074/jbc.M800679200.
    • (2008) J Biol Chem , vol.283 , Issue.39 , pp. 26624-26633
    • Prasad, A.1    Paruchuri, V.2    Preet, A.3    Latif, F.4    Ganju, R.K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.