-
1
-
-
48249085382
-
Possible role of the RhoC/ROCK pathway in progression of clear cell renal cell carcinoma
-
Abe H, Kamai T, Tsujii T, Nakamura F, Mashidori T, Mizuno T et al. (2008). Possible role of the RhoC/ROCK pathway in progression of clear cell renal cell carcinoma. Biomed Res 29: 155-161.
-
(2008)
Biomed Res
, vol.29
, pp. 155-161
-
-
Abe, H.1
Kamai, T.2
Tsujii, T.3
Nakamura, F.4
Mashidori, T.5
Mizuno, T.6
-
2
-
-
9944251987
-
Rho GTPases in human cancer: An unresolved link to upstream and downstream transcriptional regulation
-
Benitah SA, Valeron PF, van Aelst L, Marshall CJ, Lacal JC. (2004). Rho GTPases in human cancer: an unresolved link to upstream and downstream transcriptional regulation. Biochim Biophys Acta 1705: 121-132.
-
(2004)
Biochim Biophys Acta
, vol.1705
, pp. 121-132
-
-
Benitah, S.A.1
Valeron, P.F.2
Van Aelst, L.3
Marshall, C.J.4
Lacal, J.C.5
-
3
-
-
0031872076
-
Caspase-mediated activation of PAK2 during apoptosis: Proteolytic kinase activation as a general mechanism of apoptotic signal transduction?
-
Bokoch GM. (1998). Caspase-mediated activation of PAK2 during apoptosis: proteolytic kinase activation as a general mechanism of apoptotic signal transduction? Cell Death Differ 5: 637-645.
-
(1998)
Cell Death Differ
, vol.5
, pp. 637-645
-
-
Bokoch, G.M.1
-
4
-
-
0035072953
-
Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK i
-
Coleman ML, Sahai EA, Yeo M, Bosch M, Dewar A, Olson MF. (2001). Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I. Nat Cell Biol 3: 339-345.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 339-345
-
-
Coleman, M.L.1
Sahai, E.A.2
Yeo, M.3
Bosch, M.4
Dewar, A.5
Olson, M.F.6
-
5
-
-
0027225704
-
Correlation between E-cadherin expression and invasiveness in vitro in a human esophageal cancer cell line
-
Doki Y, Shiozaki H, Tahara H, Inoue M, Oka H, Iihara K et al. (1993). Correlation between E-cadherin expression and invasiveness in vitro in a human esophageal cancer cell line. Cancer Res 53: 3421-3426.
-
(1993)
Cancer Res
, vol.53
, pp. 3421-3426
-
-
Doki, Y.1
Shiozaki, H.2
Tahara, H.3
Inoue, M.4
Oka, H.5
Iihara, K.6
-
6
-
-
33947101019
-
Patterns of somatic mutation in human cancer genomes
-
Greenman C, Stephens P, Smith R, Dalgliesh GL, Hunter C, Bignell G et al. (2007). Patterns of somatic mutation in human cancer genomes. Nature 446: 153-158.
-
(2007)
Nature
, vol.446
, pp. 153-158
-
-
Greenman, C.1
Stephens, P.2
Smith, R.3
Dalgliesh, G.L.4
Hunter, C.5
Bignell, G.6
-
7
-
-
0030615004
-
P160ROCK, a Rho-associated coiled-coil forming protein kinase, works downstream of Rho and induces focal adhesions
-
Ishizaki T, Naito M, Fujisawa K, Maekawa M, Watanabe N, Saito Y et al. (1997). p160ROCK, a Rho-associated coiled-coil forming protein kinase, works downstream of Rho and induces focal adhesions. FEBS Lett 404: 118-124.
-
(1997)
FEBS Lett
, vol.404
, pp. 118-124
-
-
Ishizaki, T.1
Naito, M.2
Fujisawa, K.3
Maekawa, M.4
Watanabe, N.5
Saito, Y.6
-
8
-
-
0032935495
-
An essential part for Rho-associated kinase in the transcellular invasion of tumor cells
-
Itoh K, Yoshioka K, Akedo H, Uehata M, Ishizaki T, Narumiya S. (1999). An essential part for Rho-associated kinase in the transcellular invasion of tumor cells. Nat Med 5: 221-225.
-
(1999)
Nat Med
, vol.5
, pp. 221-225
-
-
Itoh, K.1
Yoshioka, K.2
Akedo, H.3
Uehata, M.4
Ishizaki, T.5
Narumiya, S.6
-
9
-
-
33644857442
-
The structure of dimeric rock i reveals the mechanism for ligand selectivity
-
Jacobs M, Hayakawa K, Swenson L, Bellon S, Fleming M, Taslimi P et al. (2006). The structure of dimeric rock i reveals the mechanism for ligand selectivity. J Biol Chem 281: 260-268.
-
(2006)
J Biol Chem
, vol.281
, pp. 260-268
-
-
Jacobs, M.1
Hayakawa, K.2
Swenson, L.3
Bellon, S.4
Fleming, M.5
Taslimi, P.6
-
10
-
-
0036226043
-
The rho/rho-kinase pathway is involved in the progression of testicular germ cell tumour
-
Kamai T, Arai K, Sumi S, Tsujii T, Honda M, Yamanishi T et al. (2002). The rho/rho-kinase pathway is involved in the progression of testicular germ cell tumour. BJU Int 89: 449-453.
-
(2002)
BJU Int
, vol.89
, pp. 449-453
-
-
Kamai, T.1
Arai, K.2
Sumi, S.3
Tsujii, T.4
Honda, M.5
Yamanishi, T.6
-
11
-
-
0037817325
-
Significant association of Rho/ROCK pathway with invasion and metastasis of bladder cancer
-
Kamai T, Tsujii T, Arai K, Takagi K, Asami H, Ito Y et al. (2003). Significant association of Rho/ROCK pathway with invasion and metastasis of bladder cancer. Clin Cancer Res 9: 2632-2641.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 2632-2641
-
-
Kamai, T.1
Tsujii, T.2
Arai, K.3
Takagi, K.4
Asami, H.5
Ito, Y.6
-
12
-
-
3242699514
-
Overexpression of RhoA, Rac1, and Cdc42 GTPases is associated with progression in testicular cancer
-
Kamai T, Yamanishi T, Shirataki H, Takagi K, Asami H, Ito Y et al. (2004). Overexpression of RhoA, Rac1, and Cdc42 GTPases is associated with progression in testicular cancer. Clin Cancer Res 10: 4799-4805.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 4799-4805
-
-
Kamai, T.1
Yamanishi, T.2
Shirataki, H.3
Takagi, K.4
Asami, H.5
Ito, Y.6
-
13
-
-
9244257348
-
Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho
-
Matsui T, Amano M, Yamamoto T, Chihara K, Nakafuku M, Ito M et al. (1996). Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho. EMBO J 15: 2208-2216.
-
(1996)
EMBO J
, vol.15
, pp. 2208-2216
-
-
Matsui, T.1
Amano, M.2
Yamamoto, T.3
Chihara, K.4
Nakafuku, M.5
Ito, M.6
-
14
-
-
0242298683
-
Effect of Wf-536, a novel ROCK inhibitor, against metastasis of B16 melanoma
-
Nakajima M, Hayashi K, Egi Y, Katayama K, Amano Y, Uehata M et al. (2003). Effect of Wf-536, a novel ROCK inhibitor, against metastasis of B16 melanoma. Cancer Chemother Pharmacol 52: 319-324.
-
(2003)
Cancer Chemother Pharmacol
, vol.52
, pp. 319-324
-
-
Nakajima, M.1
Hayashi, K.2
Egi, Y.3
Katayama, K.4
Amano, Y.5
Uehata, M.6
-
15
-
-
68549122708
-
Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion
-
Narumiya S, Tanji M, Ishizaki T. (2009). Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion. Cancer Metastasis Rev 28: 65-76.
-
(2009)
Cancer Metastasis Rev
, vol.28
, pp. 65-76
-
-
Narumiya, S.1
Tanji, M.2
Ishizaki, T.3
-
16
-
-
33846244179
-
Rho-associated kinase inhibitor reduces tumor recurrence after liver transplantation in a rat hepatoma model
-
Ogawa T, Tashiro H, Miyata Y, Ushitora Y, Fudaba Y, Kobayashi T et al. (2007). Rho-associated kinase inhibitor reduces tumor recurrence after liver transplantation in a rat hepatoma model. Am J Transplant 7: 347-355.
-
(2007)
Am J Transplant
, vol.7
, pp. 347-355
-
-
Ogawa, T.1
Tashiro, H.2
Miyata, Y.3
Ushitora, Y.4
Fudaba, Y.5
Kobayashi, T.6
-
17
-
-
62449294770
-
The actin cytoskeleton in cancer cell motility
-
Olson MF, Sahai E. (2009). The actin cytoskeleton in cancer cell motility. Clin Exp Metastasis 26: 273-287.
-
(2009)
Clin Exp Metastasis
, vol.26
, pp. 273-287
-
-
Olson, M.F.1
Sahai, E.2
-
19
-
-
13644252220
-
Direct cleavage of ROCK II by granzyme B induces target cell membrane blebbing in a caspase-independent manner
-
Sebbagh M, Hamelin J, Bertoglio J, Solary E, Breard J. (2005). Direct cleavage of ROCK II by granzyme B induces target cell membrane blebbing in a caspase-independent manner. J Exp Med 201: 465-471.
-
(2005)
J Exp Med
, vol.201
, pp. 465-471
-
-
Sebbagh, M.1
Hamelin, J.2
Bertoglio, J.3
Solary, E.4
Breard, J.5
-
20
-
-
0034708373
-
Rho-kinase inhibitor retards migration and in vivo dissemination of human prostate cancer cells
-
Somlyo AV, Bradshaw D, Ramos S, Murphy C, Myers CE, Somlyo AP. (2000). Rho-kinase inhibitor retards migration and in vivo dissemination of human prostate cancer cells. Biochem Biophys Res Commun 269: 652-659.
-
(2000)
Biochem Biophys Res Commun
, vol.269
, pp. 652-659
-
-
Somlyo, A.V.1
Bradshaw, D.2
Ramos, S.3
Murphy, C.4
Myers, C.E.5
Somlyo, A.P.6
-
21
-
-
0035079891
-
Intermolecular and intramolecular interactions regulate catalytic activity of myotonic dystrophy kinase-related Cdc42-binding kinase {alpha}
-
Tan I, Seow KT, Lim L, Leung T. (2001). Intermolecular and intramolecular interactions regulate catalytic activity of myotonic dystrophy kinase-related Cdc42-binding kinase {alpha}. Mol Cell Biol 21: 2767-2778.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 2767-2778
-
-
Tan, I.1
Seow, K.T.2
Lim, L.3
Leung, T.4
-
22
-
-
54449095663
-
Structure basis and unconventional lipid membrane binding properties of the PH-C1 tandem of Rho kinases
-
Wen W, Liu W, Yan J, Zhang M. (2008). Structure basis and unconventional lipid membrane binding properties of the PH-C1 tandem of Rho kinases. J Biol Chem 283: 26263-26273.
-
(2008)
J Biol Chem
, vol.283
, pp. 26263-26273
-
-
Wen, W.1
Liu, W.2
Yan, J.3
Zhang, M.4
-
23
-
-
47649112981
-
Blockade of Rho/Rho-associated coiled coil-forming kinase signaling can prevent progression of hepatocellular carcinoma in matrix metalloproteinase- dependent manner
-
Xue F, Takahara T, Yata Y, Xia Q, Nonome K, Shinno E et al. (2008). Blockade of Rho/Rho-associated coiled coil-forming kinase signaling can prevent progression of hepatocellular carcinoma in matrix metalloproteinase-dependent manner. Hepatol Res 38: 810-817.
-
(2008)
Hepatol Res
, vol.38
, pp. 810-817
-
-
Xue, F.1
Takahara, T.2
Yata, Y.3
Xia, Q.4
Nonome, K.5
Shinno, E.6
-
24
-
-
33749538874
-
The Rho kinase inhibitor fasudil inhibits tumor progression in human and rat tumor models
-
Ying H, Biroc SL, Li WW, Alicke B, Xuan JA, Pagila R et al. (2006). The Rho kinase inhibitor fasudil inhibits tumor progression in human and rat tumor models. Mol Cancer Ther 5: 2158-2164.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2158-2164
-
-
Ying, H.1
Biroc, S.L.2
Li, W.W.3
Alicke, B.4
Xuan, J.A.5
Pagila, R.6
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