-
1
-
-
68549122708
-
Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion
-
Narumiya S, Tanji M, Ishizaki T. Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion. Cancer Metastasis Rev 2009; 28: 65-76.
-
(2009)
Cancer Metastasis Rev
, vol.28
, pp. 65-76
-
-
Narumiya, S.1
Tanji, M.2
Ishizaki, T.3
-
2
-
-
73849126315
-
Rho-kinase inhibitors as therapeutics: From pan inhibition to isoform selectivity
-
Hahmann C, Schroeter T. Rho-kinase inhibitors as therapeutics: from pan inhibition to isoform selectivity. Cell Mol Life Sci 2010; 67: 171-177.
-
(2010)
Cell Mol Life Sci
, vol.67
, pp. 171-177
-
-
Hahmann, C.1
Schroeter, T.2
-
3
-
-
80053388923
-
Expression of RhoC and ROCK-1 and their effects on MAPK and Akt proteins in prostate carcinoma
-
Bu QTH, Tan J, Hu X, Wang DW. Expression of RhoC and ROCK-1 and their effects on MAPK and Akt proteins in prostate carcinoma. Chin J Oncol 2011; 33: 202-206.
-
(2011)
Chin J Oncol
, vol.33
, pp. 202-206
-
-
Bu, Q.T.H.1
Tan, J.2
Hu, X.3
Wang, D.W.4
-
4
-
-
79951581513
-
The ROCK signaling and breast cancer metastasis
-
Liu S. The ROCK signaling and breast cancer metastasis. Mol Biol Rep 2011; 38: 1363-1366.
-
(2011)
Mol Biol Rep
, vol.38
, pp. 1363-1366
-
-
Liu, S.1
-
6
-
-
0030603119
-
ROCK-I and ROCK-II, two isoforms of Rho-associated coiled-coil forming protein serine/threonine kinase in mice
-
Nakagawa O, Fujisawa K, Ishizaki T, Saito Y, Nakao K, Narumiya S. ROCK-I and ROCK-II, two isoforms of Rho-associated coiled-coil forming protein serine/threonine kinase in mice. FEBS Lett 1996; 392: 189-193.
-
(1996)
FEBS Lett
, vol.392
, pp. 189-193
-
-
Nakagawa, O.1
Fujisawa, K.2
Ishizaki, T.3
Saito, Y.4
Nakao, K.5
Narumiya, S.6
-
7
-
-
17144377069
-
RhoE function is regulated by ROCK I-mediated phosphorylation
-
Riento K, Totty N, Villalonga P, Garg R, Guasch R, Ridley AJ. RhoE function is regulated by ROCK I-mediated phosphorylation. EMBO J 2005; 24: 1170-1180.
-
(2005)
EMBO J
, vol.24
, pp. 1170-1180
-
-
Riento, K.1
Totty, N.2
Villalonga, P.3
Garg, R.4
Guasch, R.5
Ridley, A.J.6
-
8
-
-
69449094525
-
Rock2 controls TGFb signaling and inhibits mesoderm induction in zebrafish embryos
-
Zhang Y, Li X, Qi J, Wang J, Liu X, Zhang H et al. Rock2 controls TGFb signaling and inhibits mesoderm induction in zebrafish embryos. J Cell Sci 2009; 122: 2197-2207.
-
(2009)
J Cell Sci
, vol.122
, pp. 2197-2207
-
-
Zhang, Y.1
Li, X.2
Qi, J.3
Wang, J.4
Liu, X.5
Zhang, H.6
-
10
-
-
72249097073
-
Inhibition of Rho-associated kinase signaling prevents breast cancer metastasis to human bone
-
Liu S, Goldstein RH, Scepansky EM, Rosenblatt M. Inhibition of Rho-associated kinase signaling prevents breast cancer metastasis to human bone. Cancer Res 2009; 69: 8742-8751.
-
(2009)
Cancer Res
, vol.69
, pp. 8742-8751
-
-
Liu, S.1
Goldstein, R.H.2
Scepansky, E.M.3
Rosenblatt, M.4
-
11
-
-
54849186600
-
The expression and prognostic value of ROCK I and ROCK II and their role in human breast cancer
-
Lane J, Martin TA, Watkins G, Mansel RE, Jiang WG. The expression and prognostic value of ROCK I and ROCK II and their role in human breast cancer. Int J Oncol 2008; 33: 585-593.
-
(2008)
Int J Oncol
, vol.33
, pp. 585-593
-
-
Lane, J.1
Martin, T.A.2
Watkins, G.3
Mansel, R.E.4
Jiang, W.G.5
-
12
-
-
33847333362
-
Hyaluronan stimulates transformation of androgenindependent prostate cancer
-
Lin S-L, Chang D, Ying S-Y. Hyaluronan stimulates transformation of androgenindependent prostate cancer. Carcinogenesis 2006; 28: 310-320.
-
(2006)
Carcinogenesis
, vol.28
, pp. 310-320
-
-
Lin, S.-L.1
Chang, D.2
Ying, S.-Y.3
-
13
-
-
77349108330
-
Pharmacological inhibition of Rho-kinase signaling with Y-27632 blocks melanoma tumor growth
-
Routhier A, Lahey D, Monfredo N, Johnson A, Callahan W, Partington A et al. Pharmacological inhibition of Rho-kinase signaling with Y-27632 blocks melanoma tumor growth. Oncogene Rep 2010; 23: 861-867.
-
(2010)
Oncogene Rep
, vol.23
, pp. 861-867
-
-
Routhier, A.1
Lahey, D.2
Monfredo, N.3
Johnson, A.4
Callahan, W.5
Partington, A.6
-
14
-
-
33748171960
-
The c-Myc target gene network
-
Dang CV, O'Donnell KA, Zeller KI, Nguyen T, Osthus RC, Li F. The c-Myc target gene network. Sem Cancer Biol 2006; 16: 253-264.
-
(2006)
Sem Cancer Biol
, vol.16
, pp. 253-264
-
-
Dang, C.V.1
O'Donnell, K.A.2
Zeller, K.I.3
Nguyen, T.4
Osthus, R.C.5
Li, F.6
-
15
-
-
78650828153
-
Reviewing once more the c-myc and Ras collaboration: Converging at the cyclin D1-CDK4 complex and challenging basic concepts of cancer biology
-
Wang C, Lisanti MP, Liao DJ. Reviewing once more the c-myc and Ras collaboration: converging at the cyclin D1-CDK4 complex and challenging basic concepts of cancer biology. Cell Cycle 2011; 10: 57-67.
-
(2011)
Cell Cycle
, vol.10
, pp. 57-67
-
-
Wang, C.1
Lisanti, M.P.2
Liao, D.J.3
-
16
-
-
33748138585
-
Role of post-translational modifications in regulating c-Myc proteolysis, transcriptional activity and biological function
-
Hann SR. Role of post-translational modifications in regulating c-Myc proteolysis, transcriptional activity and biological function. Sem Cancer Biol 2006; 16: 288-302.
-
(2006)
Sem Cancer Biol
, vol.16
, pp. 288-302
-
-
Hann, S.R.1
-
17
-
-
0042972556
-
Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis
-
Watnick RS, Cheng Y-N, Rangarajan A, Ince TA, Weinberg RA. Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis. Cancer Cell 2003; 3: 219-231.
-
(2003)
Cancer Cell
, vol.3
, pp. 219-231
-
-
Watnick, R.S.1
Cheng, Y.-N.2
Rangarajan, A.3
Ince, T.A.4
Weinberg, R.A.5
-
18
-
-
0032935495
-
An essential part for Rho-associated kinase in the transcellular invasion of tumor cells
-
Itoh K, Yoshioka K, Akedo H, Uehata M, Ishizaki T, Narumiya S. An essential part for Rho-associated kinase in the transcellular invasion of tumor cells. Nat Med 1999; 5: 221-225.
-
(1999)
Nat Med
, vol.5
, pp. 221-225
-
-
Itoh, K.1
Yoshioka, K.2
Akedo, H.3
Uehata, M.4
Ishizaki, T.5
Narumiya, S.6
-
19
-
-
0030656619
-
Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
-
Uehata M, Ishizaki T, Satoh H, Ono T, Kawahara T, Morishita T et al. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature 1997; 389: 990-994.
-
(1997)
Nature
, vol.389
, pp. 990-994
-
-
Uehata, M.1
Ishizaki, T.2
Satoh, H.3
Ono, T.4
Kawahara, T.5
Morishita, T.6
-
20
-
-
77951978532
-
Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis
-
Chan CH, Lee SW, Li CF, Wang J, Yang WL, Wu CY et al. Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis. Nat Cell Biol 2010; 12: 457-467.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 457-467
-
-
Chan, C.H.1
Lee, S.W.2
Li, C.F.3
Wang, J.4
Yang, W.L.5
Wu, C.Y.6
-
21
-
-
0034805077
-
ASK1-signaling promotes c-Myc protein stability during apoptosis
-
Noguchi K, Kokubu A, Kitanaka C, Ichijo H, Kuchino Y. ASK1-signaling promotes c-Myc protein stability during apoptosis. Biochem Biophys Res Commun 2001; 281: 1313-1320.
-
(2001)
Biochem Biophys Res Commun
, vol.281
, pp. 1313-1320
-
-
Noguchi, K.1
Kokubu, A.2
Kitanaka, C.3
Ichijo, H.4
Kuchino, Y.5
-
22
-
-
1042289729
-
C-Jun-NH2 kinase (JNK) contributes to the regulation of c-Myc protein stability
-
Alarcon-Vargas D, Ronai Z. c-Jun-NH2 kinase (JNK) contributes to the regulation of c-Myc protein stability. J Biol Chem 2004; 279: 5008-5016.
-
(2004)
J Biol Chem
, vol.279
, pp. 5008-5016
-
-
Alarcon-Vargas, D.1
Ronai, Z.2
-
23
-
-
0037182752
-
Regulation of c-myc stability by selective stress conditions and by MEKK1 requires aa 127-189 of c-myc
-
Alarcon-Vargas D, Tansey WP, Ronai Z. Regulation of c-myc stability by selective stress conditions and by MEKK1 requires aa 127-189 of c-myc. Oncogene 2002; 21: 4384-4391.
-
(2002)
Oncogene
, vol.21
, pp. 4384-4391
-
-
Alarcon-Vargas, D.1
Tansey, W.P.2
Ronai, Z.3
-
24
-
-
1642474000
-
Hedgehog and PI-3 kinase signaling converge on Nmyc1 to promote cell cycle progression in cerebellar neuronal precursors
-
Kenney AM, Widlund HR, Rowitch DH. Hedgehog and PI-3 kinase signaling converge on Nmyc1 to promote cell cycle progression in cerebellar neuronal precursors. Development 2004; 131: 217-228.
-
(2004)
Development
, vol.131
, pp. 217-228
-
-
Kenney, A.M.1
Widlund, H.R.2
Rowitch, D.H.3
-
25
-
-
0027232220
-
Cell cycle regulation of the c-Myc transcriptional activation domain
-
Seth A, Gupta S, Davis RJ. Cell cycle regulation of the c-Myc transcriptional activation domain. Mol Cell Biol 1993; 13: 4125-4136.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 4125-4136
-
-
Seth, A.1
Gupta, S.2
Davis, R.J.3
-
26
-
-
0026657897
-
Mitosis-specific phosphorylation of the nuclear oncoproteins Myc and Myb
-
Luscher B, Eisenman RN. Mitosis-specific phosphorylation of the nuclear oncoproteins Myc and Myb. J Cell Biol 1992; 118: 775-784.
-
(1992)
J Cell Biol
, vol.118
, pp. 775-784
-
-
Luscher, B.1
Eisenman, R.N.2
-
27
-
-
48949119505
-
The estrogen and c-Myc target gene HSPC111 is over-expressed in breast cancer and associated with poor patient outcome
-
Butt A, Sergio CM, Inman C, Anderson L, McNeil C, Russell A et al. The estrogen and c-Myc target gene HSPC111 is over-expressed in breast cancer and associated with poor patient outcome. Breast Cancer Res 2008; 10: R28.
-
(2008)
Breast Cancer Res
, vol.10
, pp. R28
-
-
Butt, A.1
Sergio, C.M.2
Inman, C.3
Anderson, L.4
McNeil, C.5
Russell, A.6
-
28
-
-
28444469246
-
Silencing of microRNAs in vivo with/'antagomirs/'
-
Krutzfeldt J, Rajewsky N, Braich R, Rajeev KG, Tuschl T, Manoharan M et al. Silencing of microRNAs in vivo with/'antagomirs/'. Nature 2005; 438: 685-689.
-
(2005)
Nature
, vol.438
, pp. 685-689
-
-
Krutzfeldt, J.1
Rajewsky, N.2
Braich, R.3
Rajeev, K.G.4
Tuschl, T.5
Manoharan, M.6
-
29
-
-
84863168862
-
Up-regulated miR-17 promotes cell proliferation, tumour growth and cell cycle progression by targeting the RND3 tumour suppressor gene in colorectal carcinoma
-
Hesan Luo JZ, Dong Z, Zeng Q, Wu D, Liu L. Up-regulated miR-17 promotes cell proliferation, tumour growth and cell cycle progression by targeting the RND3 tumour suppressor gene in colorectal carcinoma. Biochem J 2012; 442: 311-321.
-
(2012)
Biochem J
, vol.442
, pp. 311-321
-
-
Hesan Luo, J.Z.1
Dong, Z.2
Zeng, Q.3
Wu, D.4
Liu, L.5
-
30
-
-
84871927424
-
ROCK2 regulates bFGF-induced proliferation of SH-SY5Y cells through GSK-3b and b-catenin pathway
-
Boku S, Nakagawa S, Toda H, Kato A, Takamura N, Omiya Y et al. ROCK2 regulates bFGF-induced proliferation of SH-SY5Y cells through GSK-3b and b-catenin pathway. Brain Res 2013; 1492: 7-17.
-
(2013)
Brain Res
, vol.1492
, pp. 7-17
-
-
Boku, S.1
Nakagawa, S.2
Toda, H.3
Kato, A.4
Takamura, N.5
Omiya, Y.6
-
31
-
-
2342526543
-
A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells
-
Yeh E, Cunningham M, Arnold H, Chasse D, Monteith T, Ivaldi G et al. A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells. Nat Cell Biol 2004; 6: 308-318.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 308-318
-
-
Yeh, E.1
Cunningham, M.2
Arnold, H.3
Chasse, D.4
Monteith, T.5
Ivaldi, G.6
-
32
-
-
73349091840
-
Nodal diffuse large B-cell lymphomas in children and adolescents: Immunohistochemical expression patterns and c-MYC translocation in relation to clinical outcome
-
Gualco G WL, Harrington Jr WJ, Bacchi CE. Nodal diffuse large B-cell lymphomas in children and adolescents: immunohistochemical expression patterns and c-MYC translocation in relation to clinical outcome. Am J Surg Pathol 2009; 33: 1815-1822.
-
(2009)
Am J Surg Pathol
, vol.33
, pp. 1815-1822
-
-
Gualco, G.W.L.1
Harrington, W.J.2
Bacchi, C.E.3
-
33
-
-
77953030981
-
Altered subcellular localization of c-Myc protein identifies aggressive B-cell lymphomas harboring a c-MYC translocation
-
Ruzinova MB CT, Rodig SJ. Altered subcellular localization of c-Myc protein identifies aggressive B-cell lymphomas harboring a c-MYC translocation. Am J Surg Pathol 2010; 34: 882-891.
-
(2010)
Am J Surg Pathol
, vol.34
, pp. 882-891
-
-
Ruzinova, M.B.C.T.1
Rodig, S.J.2
-
34
-
-
0025871767
-
Pro-Leu-Ser/Thr-Pro is a consensus primary sequence for substrate protein phosphorylation. Characterization of the phosphorylation of c-myc and c-jun proteins by an epidermal growth factor receptor threonine 669 protein kinase
-
Alvarez E, Northwood IC, Gonzalez FA, Latour DA, Seth A, Abate C et al. Pro-Leu-Ser/Thr-Pro is a consensus primary sequence for substrate protein phosphorylation. Characterization of the phosphorylation of c-myc and c-jun proteins by an epidermal growth factor receptor threonine 669 protein kinase. J Biol Chem 1991; 266: 15277-15285.
-
(1991)
J Biol Chem
, vol.266
, pp. 15277-15285
-
-
Alvarez, E.1
Northwood, I.C.2
Gonzalez, F.A.3
Latour, D.A.4
Seth, A.5
Abate, C.6
-
35
-
-
0026343730
-
A phosphorylation site located in the NH2-terminal domain of c-Myc increases transactivation of gene expression
-
Seth A, Alvarez E, Gupta S, Davis RJ. A phosphorylation site located in the NH2-terminal domain of c-Myc increases transactivation of gene expression. J Biol Chem 1991; 266: 23521-23524.
-
(1991)
J Biol Chem
, vol.266
, pp. 23521-23524
-
-
Seth, A.1
Alvarez, E.2
Gupta, S.3
Davis, R.J.4
-
36
-
-
13944252067
-
The life cycle of C-myc: From synthesis to degradation
-
Sears RC. The life cycle of C-myc: from synthesis to degradation. Cell Cycle 2004; 3: 1133-1137.
-
(2004)
Cell Cycle
, vol.3
, pp. 1133-1137
-
-
Sears, R.C.1
-
37
-
-
6944227551
-
A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size
-
Welcker M, Orian A, Grim JA, Eisenman RN, Clurman BE. A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size. Curr Biol 2004; 14: 1852-1857.
-
(2004)
Curr Biol
, vol.14
, pp. 1852-1857
-
-
Welcker, M.1
Orian, A.2
Grim, J.A.3
Eisenman, R.N.4
Clurman, B.E.5
-
38
-
-
2942650133
-
The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation
-
Welcker M, Orian A, Jin J, Grim JA, Harper JW, Eisenman RN et al. The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation. Proc Natl Acad Sci USA 2004; 101: 9085-9090.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 9085-9090
-
-
Welcker, M.1
Orian, A.2
Jin, J.3
Grim, J.A.4
Harper, J.W.5
Eisenman, R.N.6
-
39
-
-
35848942129
-
Fbw7 and Usp28 regulate myc protein stability in response to DNA damage
-
Popov N, Herold S, Llamazares M, Schulein C, Eilers M. Fbw7 and Usp28 regulate myc protein stability in response to DNA damage. Cell Cycle 2007; 6: 2327-2331.
-
(2007)
Cell Cycle
, vol.6
, pp. 2327-2331
-
-
Popov, N.1
Herold, S.2
Llamazares, M.3
Schulein, C.4
Eilers, M.5
-
40
-
-
77955283033
-
Polychlorinated biphenyls (PCBs) enhance metastatic properties of breast cancer cells by activating Rho-associated kinase (ROCK)
-
Liu S, Li S, Du Y. Polychlorinated biphenyls (PCBs) enhance metastatic properties of breast cancer cells by activating Rho-associated kinase (ROCK). PLoS One 2010; 5: e11272.
-
(2010)
PLoS One
, vol.5
, pp. e11272
-
-
Liu, S.1
Li, S.2
Du, Y.3
-
41
-
-
48249098902
-
Antagomir-17-5p abolishes the growth of therapy-resistant neuroblastoma through p21 and BIM
-
Fontana L, Fiori ME, Albini S, Cifaldi L, Giovinazzi S, Forloni M et al. Antagomir-17-5p abolishes the growth of therapy-resistant neuroblastoma through p21 and BIM. PLoS One 2008; 3: e2236.
-
(2008)
PLoS One
, vol.3
, pp. e2236
-
-
Fontana, L.1
Fiori, M.E.2
Albini, S.3
Cifaldi, L.4
Giovinazzi, S.5
Forloni, M.6
-
42
-
-
77954255681
-
Integrative genomic profiling of human prostate cancer
-
Taylor BS, Schultz N, Hieronymus H, Gopalan A, Xiao Y, Carver BS et al. Integrative genomic profiling of human prostate cancer. Cancer Cell 2010; 18: 11-22.
-
(2010)
Cancer Cell
, vol.18
, pp. 11-22
-
-
Taylor, B.S.1
Schultz, N.2
Hieronymus, H.3
Gopalan, A.4
Xiao, Y.5
Carver, B.S.6
-
43
-
-
36048955045
-
The function of heme-regulated eIF2a kinase in murine iron homeostasis and macrophage maturation
-
Liu S, RNVS Suragani, Wang F, Han A, Zhao W, Andrews NC et al. The function of heme-regulated eIF2a kinase in murine iron homeostasis and macrophage maturation. J Clin Investig 2007; 117: 3296-3305.
-
(2007)
J Clin Investig
, vol.117
, pp. 3296-3305
-
-
Liu, S.1
Suragani, R.2
Wang, F.3
Han, A.4
Zhao, W.5
Andrews, N.C.6
|