Mitochondrial protein cyclophilin-D-mediated programmed necrosis attributes to berberine-induced cytotoxicity in cultured prostate cancer cells

Biochemical and Biophysical Research Communications

Volumn 450, Issue 1, 2014, Pages 697-703

  Zhang, Long Yang ^a   Wu, Yan Lin ^a   Gao, Xing Hua ^a   Guo, Feng ^a  

^a JINAN CENTRAL HOSPITAL AFFILIATED TO SHANDONG UNIVERSITY   (China)

Author keywords

Berberine; Cyclophilin D; Mitochondrial permeability transition pore (mPTP); Programmed necrosis; Prostate cancer

Indexed keywords

ACETYLCYSTEINE; BERBERINE; CYCLOPHILIN D; CYCLOSPORIN A; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; PIFITHRIN ALPHA; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SANGLIFEHRIN A; SHORT HAIRPIN RNA; SMALL INTERFERING RNA;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; DRUG CYTOTOXICITY; GENE SILENCING; HUMAN; HUMAN CELL; LNCAP CELL LINE; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; PRIORITY JOURNAL; PROGRAMMED NECROSIS; PROSTATE CANCER; PROTEIN DEPLETION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION;

BERBERINE; CYCLOPHILIN-D; MITOCHONDRIAL PERMEABILITY TRANSITION PORE (MPTP); PROGRAMMED NECROSIS; PROSTATE CANCER;

BERBERINE; CELL LINE, TUMOR; CELL SURVIVAL; CYCLOPHILINS; HUMANS; MALE; MITOCHONDRIAL PROTEINS; NECROSIS; PROSTATIC NEOPLASMS; REACTIVE OXYGEN SPECIES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84904721550     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.06.039     Document Type: Article

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