Overexpression of FOXM1 is associated with poor prognosis and clinicopathologic stage of pancreatic ductal adenocarcinoma

Pancreas

Volumn 41, Issue 4, 2012, Pages 629-635

  Xia, Jin Tang ^a   Wang, Hua ^b   Liang, Li Jian ^b   Peng, Bao Gang ^b   Wu, Zhao Feng ^a   Chen, Lian Zhou ^a   Xue, Ling ^b   Li, Zhi ^b   Li, Wen ^b  

^a GUANGZHOU FIRST PEOPLE'S HOSPITAL   (China)

^b SUN YAT SEN UNIVERSITY   (China)

Author keywords

forkhead box M1; pancreatic ductal adenocarcinoma; prognosis

Indexed keywords

MESSENGER RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOXM1; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CANCER STAGING; CANCER SURVIVAL; FEMALE; FOLLOW UP; GENE OVEREXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; PANCREAS; PANCREAS ADENOCARCINOMA; PANCREATIC DUCTAL ADENOCARCINOMA; PRIORITY JOURNAL; PROGNOSIS; TUMOR DIFFERENTIATION;

ADULT; AGED; BLOTTING, WESTERN; CARCINOMA, PANCREATIC DUCTAL; FEMALE; FOLLOW-UP STUDIES; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEOPLASM STAGING; PANCREAS; PANCREATECTOMY; PANCREATIC NEOPLASMS; PROGNOSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SURVIVAL ANALYSIS; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION;

EID: 84862793174     PISSN: 08853177     EISSN: 15364828     Source Type: Journal    
DOI: 10.1097/MPA.0b013e31823bcef2     Document Type: Article

References (33)

1. Niederhuber JE, Brennan MF, Menck HR. The National Cancer Data Base report on pancreatic cancer. Cancer. 1995;76:1671-1677.
2. Parker SL, Tong T, Bolden S, et al. Cancer statistics. CA Cancer J Clin. 1997;47:5-27.
3. Spinelli GP, Zullo A, Romiti A, et al. Long-term survival in metastatic pancreatic cancer. A case report and review of the literature. JOP. 2006;7:486-491. (Pubitemid 44420477)
4. Fisher WE, Berger DH. Angiogenesis and antiangiogenic strategies in pancreatic cancer. Int J Gastrointest Cancer. 2003;33:79-88.
5. Ye H, Kelly TF, Samadani U, et al. Hepatocyte nuclear factor 3/fork head homolog 11 is expressed in proliferating epithelial and mesenchymal cells of embryonic and adult tissues. Mol Cell Biol. 1997;17:1626-1641. (Pubitemid 27097392)
6. Ye H, Holterman AX, Yoo KW, et al. Premature expression of the winged helix transcription factor HFH-11B in regenerating mouse liver accelerates hepatocyte entry into S phase. Mol Cell Biol. 1999;19:8570-8580. (Pubitemid 30414050)
7. Korver W, Roose J, Clevers H, et al. The winged-helix transcription factor Trident is expressed in cycling cells. Nucleic Acids Res. 1997;25:1715-1719. (Pubitemid 27303351)
8. Yao KM, Sha M, Lu Z, et al. Molecular analysis of a novel winged helix protein, WIN. Expression pattern, DNA binding property, and alternative splicing within the DNA binding domain. J Boil Chem. 1997;272:19827-19836. (Pubitemid 27340077)
9. Wonsey DR, Follettie MT. Loss of the forkhead transcription factor FoxM1 causes centrosome amplification and mitotic catastrophe. Cancer Res. 2005;65:5181-5189. (Pubitemid 40827327)
10. Teh MT, Wong ST, Neill GW, et al. FOXM1 is a downstream target of Gli1 in basal cell carcinomas. Cancer Res. 2002;62:4773-4780.
11. Kalin TV, Wang IC, Ackerson TJ, et al. Increased levels of the FoxM1 transcription factor accelerate development and progression of prostate carcinomas in both TRAMP and LADY transgenic mice. Cancer Res. 2006;66:1712-1720. (Pubitemid 43259956)
12. Obama K, Ura K, Li M, et al. Genome-wide analysis of gene expression in human intrahepatic cholangiocarcinoma. Hepatology. 2005;41:1339-1348. (Pubitemid 40770287)
13. Kim IM, Ackerson T, Ramakrishna S, et al. The forkhead Box m1 transcription factor stimulates the proliferation of tumor cells during development of lung cancer. Cancer Res. 2006;66:2153-2161.
14. Van den Boom J, Wolter M, Kuick R, et al. Characterization of gene expression profiles associated with glioma progression using oligonucleotide-based microarray analysis and real-time reverse transcription polymerase chain reaction. Am J Pathol. 2003;163:1033-1043. (Pubitemid 37040139)
15. Kalinichenko VV, Major ML, Wang X, et al. Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor. Genes Dev. 2004;18:830-850. (Pubitemid 38480894)
16. Korver W, Schilham MW, Moerer P, et al. Uncoupling of S phase and mitosis in cardiomyocytes and hepatocytes lacking the winged-helix transcription factor Trident. Curr Biol. 1998;8:1327-1330. (Pubitemid 29006708)
17. Wang X, Kiyokawa H, Dennewitz MB, et al. The forkhead box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration. Proc Natl Acad Sci U S A. 2002;99:16881-16886. (Pubitemid 36034067)
18. Laoukili J, Kooistra MR, Brás A, et al. FoxM1 is required for execution of the mitotic programme and chromosome stability. Nat Cell Biol. 2005;7:126-136. (Pubitemid 40268127)
19. Leung TW, Lin SS, Tsang AC, et al. Over-expression of FoxM1 stimulates cyclin B1 expression. FEBS Lett. 2001;507:59-66. (Pubitemid 33000299)
20. Wang IC, Chen YJ, Hughes D, et al. Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase. Mol Cell Biol. 2005;25:10875-10894. (Pubitemid 41747132)
21. Gialmanidis IP, Bravou V, Amanetopoulou SG, et al. Overexpression of hedgehog pathway molecules and FOXM1 in non-small cell. Lung Carcinomas. 2009;66:64-74.
22. Kayed H, Kleeff J, Osman T, et al. Hedgehog signaling in the normal and diseased pancreas. Pancreas. 2006;32:119-129.
23. Sobin LH, Wittekind CH. TNM Classification of Malignant Tumours. 6th ed. New York, NY: Wiley-Liss; 2002.
24. Bektas N, Haaf A, Veeck J, et al. Tight correlation between expression of the forkhead transcription factor FOXM1 and HER2 in human breast cancer. BMC Cancer. 2008;8:42.
25. LiW, Yu CP, Xia JT, et al. Sphingosine kinase 1 is associated with gastric cancer progression and poor survival of patients. Clin Cancer Res. 2009;15:1393-1399.
26. Remmele W, Stegner HE. Recommendation for uniform definition of an immunoreactive score (IRS) for immunohistochemical estrogen receptor detection (ER-ICA) in breast cancer tissue. Pathologe. 1987;8:138-140.
27. Wang Z, Banerjee S, Kong D, et al. Down-regulation of forkhead Box M1 transcription factor leads to the inhibition of invasion and angiogenesis of pancreatic cancer cells. Cancer Res. 2007;67:8293-8300. (Pubitemid 47395167)
28. Li SK, Smith DK, Leung WY, et al. FoxM1c counteracts oxidative stress induced senescence and stimulated Bmi-1 expression. J Biol Chem. 2008;283(24):16545-16553.
29. Zeng J, Wang L, Li Q, et al. FoxM1 is up-regulated in gastric cancer and its inhibition leads to cellular senescence, partially dependent on p27 kip1. J Pathol. 2009;218(4):419-427.
30. Thayer SP, di Magliano MP, Heiser PW, et al. Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis. Nature. 2003;425(6960):851- 856. (Pubitemid 37355945)
31. Katoh Y, Katoh M. Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation. Curr Mol Med. 2009;9(7):873-886.
32. Nagai S, Nakamura M, Yanai K, et al. Gli1 contributes to the invasiveness of pancreatic cancer through matrix metalloproteinase-9 activation. Cancer Sci. 2008;99:1377-1384. (Pubitemid 351761727)
33. Wang Z, Ahmad A, Banerjee S, et al. FoxM1 is a novel target of a natural agent in pancreatic cancer. Pharm Res. 2010;27(6):1159-1168.