Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-β-dependent cancer metastasis

Journal of Clinical Investigation

Volumn 124, Issue 2, 2014, Pages 564-579

  Xue, Jianfei ^a   Lin, Xia ^b   Chiu, Wen Tai ^a   Chen, Yao Hui ^a   Yu, Guanzhen ^a   Liu, Mingguang ^a   Feng, Xin Hua ^b,c   Sawaya, Raymond ^a   Medema, René H ^d   Hung, Mien Chie ^a,e,f   Huang, Suyun ^a,e  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b Michael E DeBakey Department of Surgery   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^e UNIVERSITY OF TEXAS   (United States)

^f CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; CELL LINE, TUMOR; CELL NUCLEUS; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; HEK293 CELLS; HUMANS; MICE; MICE, INBRED BALB C; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOPLASM TRANSPLANTATION; NIH 3T3 CELLS; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; SMAD4 PROTEIN; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA; UBIQUITIN; UP-REGULATION;

EID: 84893835907     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI71104     Document Type: Article

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