메뉴 건너뛰기




Volumn 25, Issue , 2014, Pages 82-91

Metabolic engineering of Escherichia coli for efficient free fatty acid production from glycerol

Author keywords

Escherichia coli; Fatty acid; Glycerol; Metabolic engineering; Redox bioavailability

Indexed keywords

BIOCHEMISTRY; CARBON; ESCHERICHIA COLI; FATTY ACIDS; METABOLIC ENGINEERING;

EID: 84904576385     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2014.06.009     Document Type: Article
Times cited : (45)

References (53)
  • 1
    • 75249095758 scopus 로고    scopus 로고
    • Conversion of glycerol to poly(3-hydroxypropionate) in recombinant Escherichia coli
    • Andreessen B., Lange A.B., Robenek H., Steinbüchel A. Conversion of glycerol to poly(3-hydroxypropionate) in recombinant Escherichia coli. Appl. Environ. Microbiol. 2010, 76(2):622-626.
    • (2010) Appl. Environ. Microbiol. , vol.76 , Issue.2 , pp. 622-626
    • Andreessen, B.1    Lange, A.B.2    Robenek, H.3    Steinbüchel, A.4
  • 2
    • 77952891180 scopus 로고    scopus 로고
    • Increasing unsaturated fatty acid contents in Escherichia coli by coexpression of three different genes
    • Cao Y., Yang J., Xian M., Xu X., Liu W. Increasing unsaturated fatty acid contents in Escherichia coli by coexpression of three different genes. Appl. Microbiol. Biotechnol. 2010, 87:271-280.
    • (2010) Appl. Microbiol. Biotechnol. , vol.87 , pp. 271-280
    • Cao, Y.1    Yang, J.2    Xian, M.3    Xu, X.4    Liu, W.5
  • 3
    • 84890844710 scopus 로고    scopus 로고
    • Efficient bioconversion of crude glycerol from biodiesel to optically pure d-lactate by metabolically engineered Escherichia coli.
    • Chen X.Z., Tian K.M., Niu D.A.D., Shen W., Algasan G., Singh S., Wang Z.X. Efficient bioconversion of crude glycerol from biodiesel to optically pure d-lactate by metabolically engineered Escherichia coli. Green Chem. 2014, 16:342-350.
    • (2014) Green Chem. , vol.16 , pp. 342-350
    • Chen, X.Z.1    Tian, K.M.2    Niu, D.A.D.3    Shen, W.4    Algasan, G.5    Singh, S.6    Wang, Z.X.7
  • 5
    • 79952582831 scopus 로고    scopus 로고
    • Metabolic engineering of Escherichia coli for the production of 1,2-propanediol from glycerol
    • Clomburg J.M., Gonzalez R. Metabolic engineering of Escherichia coli for the production of 1,2-propanediol from glycerol. Biotech. Bioeng. 2011, 108:867-879.
    • (2011) Biotech. Bioeng. , vol.108 , pp. 867-879
    • Clomburg, J.M.1    Gonzalez, R.2
  • 6
    • 84893649889 scopus 로고    scopus 로고
    • Production of shikimic acid from Escherichia coli through chemically inducible chromosomal evolution and cofactor metabolic engineering
    • Cui Y.Y., Ling C., Zhang Y.Y., Huang J., Liu J.Z. Production of shikimic acid from Escherichia coli through chemically inducible chromosomal evolution and cofactor metabolic engineering. Microb. Cell Fact. 2014, 13:21.
    • (2014) Microb. Cell Fact. , vol.13 , pp. 21
    • Cui, Y.Y.1    Ling, C.2    Zhang, Y.Y.3    Huang, J.4    Liu, J.Z.5
  • 7
    • 0034666431 scopus 로고    scopus 로고
    • Overproduction of acetyl-CoA carboxylase activity increases the rate of fatty acid biosynthesis in Escherichia coli
    • Davis M.S., Solbiati J., Cronan J.E. Overproduction of acetyl-CoA carboxylase activity increases the rate of fatty acid biosynthesis in Escherichia coli. J. Biol. Chem. 2000, 275(37):28593-28598.
    • (2000) J. Biol. Chem. , vol.275 , Issue.37 , pp. 28593-28598
    • Davis, M.S.1    Solbiati, J.2    Cronan, J.E.3
  • 8
    • 0034612342 scopus 로고    scopus 로고
    • One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
    • Datsenko K.A., Wanner B.L. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc. Natl. Acad. Sci. U. S. A. 2000, 7(12):6640-6645.
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.7 , Issue.12 , pp. 6640-6645
    • Datsenko, K.A.1    Wanner, B.L.2
  • 9
    • 23344450789 scopus 로고    scopus 로고
    • Characterization of the acetate-producing pathways in Escherichia coli
    • Dittrich C.R., Bennett G.N., San K.Y. Characterization of the acetate-producing pathways in Escherichia coli. Biotechnol. Prog. 2005, 21:1062-1067.
    • (2005) Biotechnol. Prog. , vol.21 , pp. 1062-1067
    • Dittrich, C.R.1    Bennett, G.N.2    San, K.Y.3
  • 10
    • 79953063344 scopus 로고    scopus 로고
    • Complex binding of the FabR repressor of bacterial unsaturated fatty acid biosynthesis to its cognate promoters
    • Feng Y., Cronan J.E. Complex binding of the FabR repressor of bacterial unsaturated fatty acid biosynthesis to its cognate promoters. Mol. Microbiol. 2011, 80(1):195-218.
    • (2011) Mol. Microbiol. , vol.80 , Issue.1 , pp. 195-218
    • Feng, Y.1    Cronan, J.E.2
  • 11
    • 64049099490 scopus 로고    scopus 로고
    • Different biochemical mechanisms ensure network-wide balancing of reducing equivalents in microbial metabolism
    • Fuhrer T., Sauer U. Different biochemical mechanisms ensure network-wide balancing of reducing equivalents in microbial metabolism. J. Bacteriol. 2009, 191(7):2112-2121.
    • (2009) J. Bacteriol. , vol.191 , Issue.7 , pp. 2112-2121
    • Fuhrer, T.1    Sauer, U.2
  • 12
    • 0029018327 scopus 로고
    • Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoter
    • Guzman L.M., Belin D., Carson M.J., Beckwith J. Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoter. J. Bacteriol. 1995, 177:4121-4130.
    • (1995) J. Bacteriol. , vol.177 , pp. 4121-4130
    • Guzman, L.M.1    Belin, D.2    Carson, M.J.3    Beckwith, J.4
  • 13
    • 78650570829 scopus 로고    scopus 로고
    • Application and engineering of fatty acid biosynthesis in Escherichia coli for advanced fuels and chemicals
    • Handke P., Lynch S.A., Gill R.T. Application and engineering of fatty acid biosynthesis in Escherichia coli for advanced fuels and chemicals. Metab. Eng. 2011, 13:28-37.
    • (2011) Metab. Eng. , vol.13 , pp. 28-37
    • Handke, P.1    Lynch, S.A.2    Gill, R.T.3
  • 14
    • 0029926496 scopus 로고    scopus 로고
    • Roles of the FabA and FabZ β-hydroxyacyl-acyl carrier protein dehydratases in Escherichia coli fatty acid biosynthesis
    • Heath R.J., Rock C.O. Roles of the FabA and FabZ β-hydroxyacyl-acyl carrier protein dehydratases in Escherichia coli fatty acid biosynthesis. J. Biol. Chem. 1996, 271:27795-27801.
    • (1996) J. Biol. Chem. , vol.271 , pp. 27795-27801
    • Heath, R.J.1    Rock, C.O.2
  • 15
    • 84870155643 scopus 로고    scopus 로고
    • Co-production of 3-hydroxypropionic acid and 1,3-propanediol by Klebseilla pneumoniae expressing aldH under microaerobic conditions
    • Huang Y., Li Z., Shimizu K., Ye Q. Co-production of 3-hydroxypropionic acid and 1,3-propanediol by Klebseilla pneumoniae expressing aldH under microaerobic conditions. Bioresour. Technol. 2013, 128:505-512.
    • (2013) Bioresour. Technol. , vol.128 , pp. 505-512
    • Huang, Y.1    Li, Z.2    Shimizu, K.3    Ye, Q.4
  • 16
    • 84886747287 scopus 로고    scopus 로고
    • Metabolic engineering and transhydrogenase effects on NADPH availability in Escherichia coli
    • Jan J., Martinez I., Wang Y., Bennett G.N., San K.Y. Metabolic engineering and transhydrogenase effects on NADPH availability in Escherichia coli. Biotechnol. Prog. 2013, 29:1124-1130.
    • (2013) Biotechnol. Prog. , vol.29 , pp. 1124-1130
    • Jan, J.1    Martinez, I.2    Wang, Y.3    Bennett, G.N.4    San, K.Y.5
  • 17
    • 84862202568 scopus 로고    scopus 로고
    • Improved production of long-chain fatty acid in Escherichia coli by an engineering elongation cycle during fatty acid synthesis (FAS) through genetic manipulation
    • Jeon E.Y., Lee S.H., Yoon Y.J. Improved production of long-chain fatty acid in Escherichia coli by an engineering elongation cycle during fatty acid synthesis (FAS) through genetic manipulation. J. Microbiol. Biotechnol. 2012, 22:990-999.
    • (2012) J. Microbiol. Biotechnol. , vol.22 , pp. 990-999
    • Jeon, E.Y.1    Lee, S.H.2    Yoon, Y.J.3
  • 18
    • 77955429093 scopus 로고    scopus 로고
    • High NADPH/NADP+ ratio improves thymidine production by a metabolically engineered Escherichia coli strain
    • Lee H.C., Kim J.S., Jang W., Kim S.Y. High NADPH/NADP+ ratio improves thymidine production by a metabolically engineered Escherichia coli strain. J Biotechnol. 2010, 149:24-32.
    • (2010) J Biotechnol. , vol.149 , pp. 24-32
    • Lee, H.C.1    Kim, J.S.2    Jang, W.3    Kim, S.Y.4
  • 19
    • 77953044867 scopus 로고    scopus 로고
    • A process for microbial hydrocarbon synthesis: overproduction of fatty acids in Escherichia coli and catalytic conversion to alkanes
    • Lennen R.M., Braden D.J., West R.A., Dumesic J.A., Pfleger B.F. A process for microbial hydrocarbon synthesis: overproduction of fatty acids in Escherichia coli and catalytic conversion to alkanes. Biotechnol. Bioeng. 2010, 106:193-202.
    • (2010) Biotechnol. Bioeng. , vol.106 , pp. 193-202
    • Lennen, R.M.1    Braden, D.J.2    West, R.A.3    Dumesic, J.A.4    Pfleger, B.F.5
  • 20
    • 84862166207 scopus 로고    scopus 로고
    • Effect of acetate formation pathway and long chain fatty acid CoA-ligase on the free fatty acid production in E. coli expressing acy-ACP thioesterase from Ricinus communis
    • Li M., Zhang X.J., Agrawal A., San K.Y. Effect of acetate formation pathway and long chain fatty acid CoA-ligase on the free fatty acid production in E. coli expressing acy-ACP thioesterase from Ricinus communis. Metab. Eng. 2012, 14:380-387.
    • (2012) Metab. Eng. , vol.14 , pp. 380-387
    • Li, M.1    Zhang, X.J.2    Agrawal, A.3    San, K.Y.4
  • 21
    • 33745282141 scopus 로고    scopus 로고
    • Effect of sucA or sucC gene knockout on the metabolism in Escherichia coli based on gene expressions, enzyme activities, intracellular metabolite concentrations and metabolic fluxes by 13C-labeling experiments
    • Li M., Ho P.Y., Yao S.J., Shimizu K. Effect of sucA or sucC gene knockout on the metabolism in Escherichia coli based on gene expressions, enzyme activities, intracellular metabolite concentrations and metabolic fluxes by 13C-labeling experiments. Biochem. Eng. J. 2006, 30:286-296.
    • (2006) Biochem. Eng. J. , vol.30 , pp. 286-296
    • Li, M.1    Ho, P.Y.2    Yao, S.J.3    Shimizu, K.4
  • 22
    • 0027389215 scopus 로고
    • Growth rate regulation of Escherichia coli acetyl coenzyme A carboxylase, which catalyzes the first committed step of lipid biosynthesis
    • Li S.J., Cronan J.E. Growth rate regulation of Escherichia coli acetyl coenzyme A carboxylase, which catalyzes the first committed step of lipid biosynthesis. J. Bacteriol. 1993, 175(2):332-340.
    • (1993) J. Bacteriol. , vol.175 , Issue.2 , pp. 332-340
    • Li, S.J.1    Cronan, J.E.2
  • 23
    • 12744254193 scopus 로고    scopus 로고
    • Genetic reconstruction of the aerobic central metabolism in Escherichia coli for the absolute aerobic production of succinate
    • Lin H., Bennett G.N., San K.Y. Genetic reconstruction of the aerobic central metabolism in Escherichia coli for the absolute aerobic production of succinate. Biotechnol. Bioeng. 2005, 89:148-156.
    • (2005) Biotechnol. Bioeng. , vol.89 , pp. 148-156
    • Lin, H.1    Bennett, G.N.2    San, K.Y.3
  • 24
    • 77953022686 scopus 로고    scopus 로고
    • Quantitative analysis and engineering of fatty acid biosynthesis in E. coli
    • Liu T., Vor H., Khosla C. Quantitative analysis and engineering of fatty acid biosynthesis in E. coli. Metab. Eng. 2010, 12:378-386.
    • (2010) Metab. Eng. , vol.12 , pp. 378-386
    • Liu, T.1    Vor, H.2    Khosla, C.3
  • 25
    • 57049105699 scopus 로고    scopus 로고
    • Overproduction of free fatty acids in E. coli: implications for biodiesel production
    • Lu X., Vora H., Khosla C. Overproduction of free fatty acids in E. coli: implications for biodiesel production. Metab. Eng. 2008, 10:333-339.
    • (2008) Metab. Eng. , vol.10 , pp. 333-339
    • Lu, X.1    Vora, H.2    Khosla, C.3
  • 26
    • 77954254857 scopus 로고    scopus 로고
    • Escherichia coli strains engineered for homofermentative production of d-lactic acid from glycerol
    • Mazumdar S., Clomburg J.M., Gonzalez R. Escherichia coli strains engineered for homofermentative production of d-lactic acid from glycerol. Appl. Environ. Microbiol. 2010, 76:4327-4336.
    • (2010) Appl. Environ. Microbiol. , vol.76 , pp. 4327-4336
    • Mazumdar, S.1    Clomburg, J.M.2    Gonzalez, R.3
  • 27
    • 84872767064 scopus 로고    scopus 로고
    • Efficient synthesis of l-lactic acid from glycerol by metabolically engineered Escherichia coli
    • Mazumdar S., Blankschien M.D., Clomburg J.M., Gonzalez R. Efficient synthesis of l-lactic acid from glycerol by metabolically engineered Escherichia coli. Microb. Cell Fact. 2013, 12:7.
    • (2013) Microb. Cell Fact. , vol.12 , pp. 7
    • Mazumdar, S.1    Blankschien, M.D.2    Clomburg, J.M.3    Gonzalez, R.4
  • 28
    • 0028584330 scopus 로고
    • An Escherichia coli gene (FabZ) encoding (3R)-hydroxymyristoyl acyl carrier protein dehydrase
    • Mohan S., Kelly T.M., Eveland S.S., Raetz C.R., Anderson M.S. An Escherichia coli gene (FabZ) encoding (3R)-hydroxymyristoyl acyl carrier protein dehydrase. J. Biol. Chem. 1994, 269:32896-32903.
    • (1994) J. Biol. Chem. , vol.269 , pp. 32896-32903
    • Mohan, S.1    Kelly, T.M.2    Eveland, S.S.3    Raetz, C.R.4    Anderson, M.S.5
  • 30
    • 41649085020 scopus 로고    scopus 로고
    • Analyses of Mlc-IIBGlc interaction and a plausible molecular mechanism of Mlc inactivation by membrane sequestration
    • Nam T.W., Jung H.I., An Y.J., Park Y.H., Lee S.H., Seok Y.J., Cha S.S. Analyses of Mlc-IIBGlc interaction and a plausible molecular mechanism of Mlc inactivation by membrane sequestration. Proc. Natl. Acad. Sci. U. S. A. 2008, 105(10):3751-3756.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , Issue.10 , pp. 3751-3756
    • Nam, T.W.1    Jung, H.I.2    An, Y.J.3    Park, Y.H.4    Lee, S.H.5    Seok, Y.J.6    Cha, S.S.7
  • 31
    • 38049156419 scopus 로고    scopus 로고
    • Poly(3-hydroxybutyrate) synthesis from glycerol by a recombinant Escherichia coli arcA mutant in fed-batch microaerobic cultures
    • Nikel P.I., Pettinari M.J., Galvagno M.A., Méndez B.S. Poly(3-hydroxybutyrate) synthesis from glycerol by a recombinant Escherichia coli arcA mutant in fed-batch microaerobic cultures. Appl. Microbiol. Biotechnol. 2008, 77(6):1337-1343.
    • (2008) Appl. Microbiol. Biotechnol. , vol.77 , Issue.6 , pp. 1337-1343
    • Nikel, P.I.1    Pettinari, M.J.2    Galvagno, M.A.3    Méndez, B.S.4
  • 32
    • 43549122821 scopus 로고    scopus 로고
    • Platform chemicals for a biorenewable chemical industry
    • Nikolau B.J., Perera M.A., Brachova L., Shanks B. Platform chemicals for a biorenewable chemical industry. Plant J. 2008, 54:536-545.
    • (2008) Plant J. , vol.54 , pp. 536-545
    • Nikolau, B.J.1    Perera, M.A.2    Brachova, L.3    Shanks, B.4
  • 33
    • 0034008457 scopus 로고    scopus 로고
    • Gene expression profiling by DNA microarrays and metabolic fluxes in Escherichia coli
    • Oh M.K., Liao J.C. Gene expression profiling by DNA microarrays and metabolic fluxes in Escherichia coli. Biotechnol. Prog. 2000, 16:278-286.
    • (2000) Biotechnol. Prog. , vol.16 , pp. 278-286
    • Oh, M.K.1    Liao, J.C.2
  • 35
    • 84904555924 scopus 로고    scopus 로고
    • Bacteria and method for synthesizing fatty acids. WO/2013/059218, USA.
    • San, K.Y., Li, M., 2013. Bacteria and method for synthesizing fatty acids. Vol. WO/2013/059218, USA.
    • (2013)
    • San, K.Y.1    Li, M.2
  • 36
    • 84904577501 scopus 로고    scopus 로고
    • Bacteria and method for synthesizing fatty acids. WO/2011/116279, USA.
    • San, K.Y., Li, M., Zhang, X., 2011. Bacteria and method for synthesizing fatty acids. Vol. WO/2011/116279, USA.
    • (2011)
    • San, K.Y.1    Li, M.2    Zhang, X.3
  • 37
    • 33646045867 scopus 로고    scopus 로고
    • Effect of overexpression of a soluble pyridine nucleotide transhydrogenase (UdhA) on the production of poly(3-hydroxybutyrate) in Escherichia coli
    • Sánchez A.M., Andrew J., Hussein I., Bennett G.N., San K-Y. Effect of overexpression of a soluble pyridine nucleotide transhydrogenase (UdhA) on the production of poly(3-hydroxybutyrate) in Escherichia coli. Biotechnol. Prog. 2006, 22(2):420-425.
    • (2006) Biotechnol. Prog. , vol.22 , Issue.2 , pp. 420-425
    • Sánchez, A.M.1    Andrew, J.2    Hussein, I.3    Bennett, G.N.4    San, K.-Y.5
  • 38
    • 1342325419 scopus 로고    scopus 로고
    • The soluble and membrane-bound transhydrogenases UdhA and PntAB have divergent functions in NADPH metabolism of Escherichia coli
    • Sauer U., Canonaco F., Heri S., Perrenoud A., Fischer E. The soluble and membrane-bound transhydrogenases UdhA and PntAB have divergent functions in NADPH metabolism of Escherichia coli. J. Biol. Chem. 2004, 279(8):6613-6619.
    • (2004) J. Biol. Chem. , vol.279 , Issue.8 , pp. 6613-6619
    • Sauer, U.1    Canonaco, F.2    Heri, S.3    Perrenoud, A.4    Fischer, E.5
  • 39
    • 84872131864 scopus 로고    scopus 로고
    • Activating transhydrogenase and NAD kinase in combination for improving isobutanol production
    • Shi A., Zhu X., Lu J., Zhang X., Ma Y. Activating transhydrogenase and NAD kinase in combination for improving isobutanol production. Metab. Eng. 2013, 16:1-10.
    • (2013) Metab. Eng. , vol.16 , pp. 1-10
    • Shi, A.1    Zhu, X.2    Lu, J.3    Zhang, X.4    Ma, Y.5
  • 41
    • 3843085214 scopus 로고    scopus 로고
    • Glc is directly responsible for the inactivation of the global repressor Mlc in Escherichia coli
    • Glc is directly responsible for the inactivation of the global repressor Mlc in Escherichia coli. Mol. Microbiol. 2004, 53(3):941-951.
    • (2004) Mol. Microbiol. , vol.53 , Issue.3 , pp. 941-951
    • Tanaka, Y.1    Itoh, F.2    Kimata, K.3    Aiba, H.4
  • 42
    • 84868098920 scopus 로고    scopus 로고
    • Controlled biosynthesis of odd-chain fuels and chemicals via engineered modular metabolic pathways
    • Tseng H.C., Prather K.L. Controlled biosynthesis of odd-chain fuels and chemicals via engineered modular metabolic pathways. Proc. Natl. Acad. Sci. U. S. A. 2012, 109:17925-17930.
    • (2012) Proc. Natl. Acad. Sci. U. S. A. , vol.109 , pp. 17925-17930
    • Tseng, H.C.1    Prather, K.L.2
  • 43
    • 0028149560 scopus 로고
    • Alteration of the specificity and regulation of fatty acid synthesis of Escherichia coli by expression of plant medium-chain acyl-acyl carrier protein thioesterase
    • Voelker T.A., Davies H.M. Alteration of the specificity and regulation of fatty acid synthesis of Escherichia coli by expression of plant medium-chain acyl-acyl carrier protein thioesterase. J. Bacteriol. 1994, 176:732-7327.
    • (1994) J. Bacteriol. , vol.176 , pp. 732-7327
    • Voelker, T.A.1    Davies, H.M.2
  • 44
    • 84892831820 scopus 로고    scopus 로고
    • Improvement of NADPH bioavailability in Escherichia coli by replacing NAD(+)-dependent glyceraldehyde-3-phosphate dehydrogenase GapA with NADP (+)-dependent GapB from Bacillus subtilis and addition of NAD kinase
    • Wang Y., San K.Y., Bennett G.N. Improvement of NADPH bioavailability in Escherichia coli by replacing NAD(+)-dependent glyceraldehyde-3-phosphate dehydrogenase GapA with NADP (+)-dependent GapB from Bacillus subtilis and addition of NAD kinase. J. Ind. Microbiol. Biotechnol. 2013, 40:1449-1460.
    • (2013) J. Ind. Microbiol. Biotechnol. , vol.40 , pp. 1449-1460
    • Wang, Y.1    San, K.Y.2    Bennett, G.N.3
  • 45
    • 84877804801 scopus 로고    scopus 로고
    • Modular optimization of multi-gene pathways for fatty acids production in E. coli
    • Xu P., Gu Q., Wang W., Wong L., Bower A.G., Collins C.H., Koffas M.A. Modular optimization of multi-gene pathways for fatty acids production in E. coli. Nat. Commun. 2013, 4:1409.
    • (2013) Nat. Commun. , vol.4 , pp. 1409
    • Xu, P.1    Gu, Q.2    Wang, W.3    Wong, L.4    Bower, A.G.5    Collins, C.H.6    Koffas, M.A.7
  • 46
    • 80052021573 scopus 로고    scopus 로고
    • Genome-scale metabolic network modeling results in minimal interventions that cooperatively force carbon flux towards malonyl-CoA
    • Xu P., Ranganathan S., Fowler Z.L., Maranas C.D., Koffas M.A. Genome-scale metabolic network modeling results in minimal interventions that cooperatively force carbon flux towards malonyl-CoA. Metab. Eng. 2011, 13(5):578-587.
    • (2011) Metab. Eng. , vol.13 , Issue.5 , pp. 578-587
    • Xu, P.1    Ranganathan, S.2    Fowler, Z.L.3    Maranas, C.D.4    Koffas, M.A.5
  • 47
    • 84858056650 scopus 로고    scopus 로고
    • Value-added uses for crude glycerol-a byproduct of biodiesel production
    • Yang F., Hanna M.A., Sun R. Value-added uses for crude glycerol-a byproduct of biodiesel production. Biotechnol. Biofuels 2012, 5:13.
    • (2012) Biotechnol. Biofuels , vol.5 , pp. 13
    • Yang, F.1    Hanna, M.A.2    Sun, R.3
  • 48
    • 57049188930 scopus 로고    scopus 로고
    • Engineering Escherichia coli for the efficient conversion of glycerol to ethanol and co-products
    • Yazdani S.S., Gonzalez R. Engineering Escherichia coli for the efficient conversion of glycerol to ethanol and co-products. Metab. Eng. 2008, 10:340-351.
    • (2008) Metab. Eng. , vol.10 , pp. 340-351
    • Yazdani, S.S.1    Gonzalez, R.2
  • 49
    • 82755161073 scopus 로고    scopus 로고
    • Microbial production of diols as platform chemicals: recent progresses
    • Zeng A.P., Sabra W. Microbial production of diols as platform chemicals: recent progresses. Curr. Opin. Biotechnol. 2011, 22:749-757.
    • (2011) Curr. Opin. Biotechnol. , vol.22 , pp. 749-757
    • Zeng, A.P.1    Sabra, W.2
  • 50
    • 63649137435 scopus 로고    scopus 로고
    • Improving cellular malonyl-CoA level in Escherichia coli via metabolic engineering
    • Zha W., Rubin-Pitel S.B., Shao Z., Zhao H. Improving cellular malonyl-CoA level in Escherichia coli via metabolic engineering. Metab. Eng. 2009, 11(3):192-198.
    • (2009) Metab. Eng. , vol.11 , Issue.3 , pp. 192-198
    • Zha, W.1    Rubin-Pitel, S.B.2    Shao, Z.3    Zhao, H.4
  • 51
    • 80555149222 scopus 로고    scopus 로고
    • Efficient free fatty acid production in Escherichia coli using plant acyl-ACP thioesterases
    • Zhang X.J., Li M., Agrawal A., San K.Y. Efficient free fatty acid production in Escherichia coli using plant acyl-ACP thioesterases. Metab. Eng. 2011, 13:713-722.
    • (2011) Metab. Eng. , vol.13 , pp. 713-722
    • Zhang, X.J.1    Li, M.2    Agrawal, A.3    San, K.Y.4
  • 52
    • 77950580812 scopus 로고    scopus 로고
    • Fermentation of glycerol to succinate by metabolically engineered strains of Escherichia coli
    • Zhang X.L., Shanmugam K.T., Ingram L.O. Fermentation of glycerol to succinate by metabolically engineered strains of Escherichia coli. Appl. Environ. Microbiol. 2010, 76(8):2397-2401.
    • (2010) Appl. Environ. Microbiol. , vol.76 , Issue.8 , pp. 2397-2401
    • Zhang, X.L.1    Shanmugam, K.T.2    Ingram, L.O.3
  • 53
    • 0037013190 scopus 로고    scopus 로고
    • The FabR (YijC) transcription factor regulates unsaturated fatty acid biosynthesis in Escherichia coli
    • Zhang Y.M., Marrakchi H., Rock C.O. The FabR (YijC) transcription factor regulates unsaturated fatty acid biosynthesis in Escherichia coli. J. Biol. Chem. 2002, 77(18):15558-15565.
    • (2002) J. Biol. Chem. , vol.77 , Issue.18 , pp. 15558-15565
    • Zhang, Y.M.1    Marrakchi, H.2    Rock, C.O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.