Akt phosphorylation and regulation of transketolase is a nodal point for amino acid control of purine synthesis

Molecular Cell

Volumn 55, Issue 2, 2014, Pages 264-276

  Saha, Arindam ^a   Connelly, Stephen ^b   Jiang, Jingjing ^a   Zhuang, Shunhui ^a   Amador, Deron T ^a   Phan, Tony ^a   Pilz, Renate B ^a   Boss, Gerry R ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CARBON; ESSENTIAL AMINO ACID; I KAPPA B KINASE; LYSINE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; PROTEIN KINASE B; PURINE; THREONINE; TRANSKETOLASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GLUCOSE UTILIZATION; MOUSE; NONHUMAN; PENTOSE PHOSPHATE CYCLE; PURINE SYNTHESIS; REGULATORY MECHANISM; RNA SYNTHESIS;

MAMMALIA; MUS;

AMINO ACID SEQUENCE; AMINO ACIDS; ANIMALS; CONSERVED SEQUENCE; HELA CELLS; HUMANS; I-KAPPA B KINASE; MALE; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; MULTIPROTEIN COMPLEXES; OXIDATION-REDUCTION; PHOSPHORIBOSYL PYROPHOSPHATE; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-AKT; PURINES; TOR SERINE-THREONINE KINASES; TRANSKETOLASE;

EID: 84904546350     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2014.05.028     Document Type: Article

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