Oxidative stress induced age dependent meibomian gland dysfunction in Cu, Zn-superoxide dismutase-1 (Sod1) knockout mice

PLoS ONE

Volumn 9, Issue 7, 2014, Pages

  Ibrahim, Osama M A ^a   Dogru, Murat ^a,b   Matsumoto, Yukihiro ^a   Igarashi, Ayako ^b   Kojima, Takashi ^a   Wakamatsu, Tais Hitomi ^a   Inaba, Takaaki ^a   Shimizu, Takahiko ^c   Shimazaki, Jun ^b   Tsubota, Kazuo ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TOKYO DENTAL COLLEGE   (Japan)

^c CHIBA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYNONENAL; 8 HYDROXYDEOXYGUANOSINE; CD45 ANTIGEN; COPPER ZINC SUPEROXIDE DISMUTASE; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA; INTERLEUKIN-6, MOUSE; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DAMAGE; CELL INFILTRATION; CELL ULTRASTRUCTURE; CONTROLLED STUDY; COTTON THREAD TEAR TEST; DISEASE ASSOCIATION; DNA DAMAGE; DRY EYE; ENZYME DEFICIENCY; EPITHELIUM CELL; KNOCKOUT MOUSE; LACRIMATION; MALE; MEIBOMIAN GLAND DYSFUNCTION; MITOCHONDRION SWELLING; MOUSE; NONHUMAN; OCULAR SURFACE DISEASE; OCULAR VITAL STAINING TEST; OXIDATIVE STRESS; SOD1 GENE; TEAR FUNCTION TEST; VISUAL SYSTEM EXAMINATION; AGE; ANIMAL; BLOOD; C57BL MOUSE; CHEMISTRY; CORNEA EPITHELIUM; DEFICIENCY; DRY EYE SYNDROMES; ENZYMOLOGY; INFLAMMATION; LACRIMAL FLUID; LIPID PEROXIDATION; MEIBOMIAN GLAND; PATHOLOGY; PATHOPHYSIOLOGY; SECRETION (PROCESS);

AGE FACTORS; ANIMALS; APOPTOSIS; DNA DAMAGE; DRY EYE SYNDROMES; EPITHELIUM, CORNEAL; INFLAMMATION; INTERLEUKIN-6; LIPID PEROXIDATION; MALE; MEIBOMIAN GLANDS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OXIDATIVE STRESS; SUPEROXIDE DISMUTASE; TEARS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84904512205     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0099328     Document Type: Article

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