Skin atrophy in cytoplasmic SOD-deficient mice and its complete recovery using a vitamin C derivative

Biochemical and Biophysical Research Communications

Volumn 382, Issue 2, 2009, Pages 457-461

  Murakami, Kazuma ^a   Inagaki, Jun ^a,b   Saito, Mitsuru ^c   Ikeda, Yasutaka ^a,b   Tsuda, Chizuru ^a   Noda, Yoshihiro ^a   Kawakami, Satoru ^a,b,d   Shirasawa, Takuji ^a,b,e   Shimizu, Takahiko ^a,b,d  

^a TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^b Anti Aging Science Inc   (Japan)

^c JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

^e JUNTENDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Ageing; Collagen; Elastin; Skin atrophy; Superoxide dismutase; Vitamin C

Indexed keywords

APPRECIER; ASCORBIC ACID; ASCORBIC ACID DERIVATIVE; ASCORBYL 2 PHOSPHATE 6 PALMITATE; COLLAGEN; COPPER ZINC SUPEROXIDE DISMUTASE; ELASTIN; HYDROXYPROLINE; PLACEBO; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; COLLAGEN DEGRADATION; CONTROLLED STUDY; CUTANEOUS PARAMETERS; CYTOPLASM; DISEASE COURSE; DRUG EFFECT; DRUG MECHANISM; DRUG STRUCTURE; ELASTIC FIBER; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN ATROPHY; STRUCTURE ACTIVITY RELATION;

ANIMALS; ASCORBIC ACID; ATROPHY; COLLAGEN; CYTOPLASM; ELASTIN; MICE; MICE, KNOCKOUT; SKIN; SKIN AGING; SUPEROXIDE DISMUTASE;

MUS;

EID: 63349111713     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.03.053     Document Type: Article

References (30)

1. Glogau R.G. Physiologic and structural changes associated with aging skin. Dermatol. Clin. 15 (1997) 555-559
2. Ichihashi M., Ueda M., Budiyanto A., Bito T., Oka M., Fukunaga M., Tsuru K., and Horikawa T. UV-induced skin damage. Toxicology 189 (2003) 21-39
3. Reiners Jr. J.J., Kodari E., Cappel R.E., and Gilbert H.F. Assessment of the antioxidant/prooxidant status of murine skin following topical treatment with 12-O-tetradecanoylphorbol-13-acetate and throughout the ontogeny of skin cancer. Part II: quantitation of glutathione and glutathione disulfide. Carcinogenesis 12 (1991) 2345-2352
4. Dhar A., Young M.R., and Colburn N.H. The role of AP-1, NF-kappaB and ROS/NOS in skin carcinogenesis: the JB6 model is predictive. Mol. Cell. Biochem. 234-235 (2002) 185-193
5. Kuro-o M., Matsumura Y., Aizawa H., Kawaguchi H., Suga T., Utsugi T., Ohyama Y., Kurabayashi M., Kaname T., Kume E., Iwasaki H., Iida A., Shiraki-Iida T., Nishikawa S., Nagai R., and Nabeshima Y.I. Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Nature 390 (1997) 45-51
6. Kemp C.J. Multistep skin cancer in mice as a model to study the evolution of cancer cells. Semin. Cancer Biol. 15 (2005) 460-473
7. Tong W.M., Cortes U., and Wang Z.Q. Poly(ADP-ribose) polymerase: a guardian angel protecting the genome and suppressing tumorigenesis. Biochim. Biophys. Acta 1552 (2001) 27-37
8. Peterkofsky B. Ascorbate requirement for hydroxylation and secretion of procollagen: relationship to inhibition of collagen synthesis in scurvy. Am. J. Clin. Nutr. 54 (1991) 1135S-1140S
9. Imamura Y., Noda S., Hashizume K., Shinoda K., Yamaguchi M., Uchiyama S., Shimizu T., Mizushima Y., Shirasawa T., and Tsubota K. Drusen, choroidal neovascularization, and retinal pigment epithelium dysfunction in SOD1-deficient mice: a model of age-related macular degeneration. Proc. Natl. Acad. Sci. USA 103 (2006) 11282-11287
10. Uchiyama S., Shimizu T., and Shirasawa T. CuZn-SOD deficiency causes ApoB degradation and induces hepatic lipid accumulation by impaired lipoprotein secretion in mice. J. Biol. Chem. 281 (2006) 31713-31719
11. Elchuri S., Oberley T.D., Qi W., Eisenstein R.S., Jackson Roberts L., Van Remmen H., Epstein C.J., and Huang T.T. CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life. Oncogene 24 (2005) 367-380
12. Iuchi Y., Okada F., Onuma K., Onoda T., Asao H., Kobayashi M., and Fujii J. Elevated oxidative stress in erythrocytes due to a SOD1 deficiency causes anaemia and triggers autoantibody production. Biochem. J. 402 (2007) 219-227
13. Muller F.L., Song W., Liu Y., Chaudhuri A., Pieke-Dahl S., Strong R., Huang T.T., Epstein C.J., Roberts II L.J., Csete M., Faulkner J.A., and Van Remmen H. Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy. Free Radic. Biol. Med. 40 (2006) 1993-2004
14. Nojiri H., Shimizu T., Funakoshi M., Yamaguchi O., Zhou H., Kawakami S., Ohta Y., Sami M., Tachibana T., Ishikawa H., Kurosawa H., Kahn R.C., Otsu K., and Shirasawa T. Oxidative stress causes heart failure with impaired mitochondrial respiration. J. Biol. Chem. 281 (2006) 33789-33801
15. Saito M., Marumo K., Fujii K., and Ishioka N. Single-column high-performance liquid chromatographic-fluorescence detection of immature, mature, and senescent cross-links of collagen. Anal. Biochem. 253 (1997) 26-32
16. Shimazaki M., Nakamura K., Kii I., Kashima T., Amizuka N., Li M., Saito M., Fukuda K., Nishiyama T., Kitajima S., Saga Y., Fukayama M., Sata M., and Kudo A. Periostin is essential for cardiac healing after acute myocardial infarction. J. Exp. Med. 205 (2008) 295-303
17. Ryu A., Naru E., Arakane K., Masunaga T., Shinmoto K., Nagano T., Hirobe M., and Mashiko S. Cross-linking of collagen by singlet oxygen generated with UV-A. Chem. Pharm. Bull. (Tokyo) 45 (1997) 1243-1247
18. Blanck T.J., and Peterkofsky B. The stimulation of collagen secretion by ascorbate as a result of increased proline hydroxylation in chick embryo fibroblasts. Arch. Biochem. Biophys. 171 (1975) 259-267
19. de Clerck Y.A., and Jones P.A. The effect of ascorbic acid on the nature and production of collagen and elastin by rat smooth-muscle cells. Biochem. J. 186 (1980) 217-225
20. Murad S., Grove D., Lindberg K.A., Reynolds G., Sivarajah A., and Pinnell S.R. Regulation of collagen synthesis by ascorbic acid. Proc. Natl. Acad. Sci. USA 78 (1981) 2879-2882
21. Zern M.A., Schwartz E., Giambrone M.A., and Blumenfeld O.O. Ascorbate-generated endogenous extracellular matrix affects cell protein synthesis in calf aortic smooth muscle cells. Exp. Cell Res. 160 (1985) 307-318
22. Bhattacharyya T.K., and Thomas J.R. Histomorphologic changes in aging skin: observations in the CBA mouse model. Arch. Facial Plast. Surg. 6 (2004) 21-25
23. Oikarinen A. Aging of the skin connective tissue: how to measure the biochemical and mechanical properties of aging dermis. Photodermatol. Photoimmunol. Photomed. 10 (1994) 47-52
24. Kligman L.H., Akin F.J., and Kligman A.M. Prevention of ultraviolet damage to the dermis of hairless mice by sunscreens. J. Invest. Dermatol. 78 (1982) 181-189
25. Walker-Smith J.A. Cow milk-sensitive enteropathy: predisposing factors and treatment. J. Pediatr. 121 (1992) S111-S115
26. Liu J.W., Nagao N., Kageyama K., and Miwa N. Antimetastatic and anti-invasive ability of phospho-ascorbyl palmitate through intracellular ascorbate enrichment and the resultant antioxidant action. Oncol. Res. 11 (1999) 479-487
27. Liu J.W., Nagao N., Kageyama K., and Miwa N. Anti-metastatic effect of an autooxidation-resistant and lipophilic ascorbic acid derivative through inhibition of tumor invasion. Anticancer Res. 20 (2000) 113-118
28. Liu J.W., Kayasuga A., Nagao N., Masatsuji-Kato E., Tuzuki T., and Miwa N. Repressions of actin assembly and RhoA localization are involved in inhibition of tumor cell motility by lipophilic ascorbyl phosphate. Int. J. Oncol. 23 (2003) 1561-1567
29. Inui S., and Itami S. Perifollicular pigmentation is the first target for topical vitamin C derivative ascorbyl 2-phosphate 6-palmitate (APPS): randomized, single-blinded, placebo-controlled study. J. Dermatol. 34 (2007) 221-223
30. Rhie G., Shin M.H., Seo J.Y., Choi W.W., Cho K.H., Kim K.H., Park K.C., Eun H.C., and Chung J.H. Aging- and photoaging-dependent changes of enzymic and nonenzymic antioxidants in the epidermis and dermis of human skin in vivo. J. Invest. Dermatol. 117 (2001) 1212-1217