메뉴 건너뛰기




Volumn 140, Issue 8, 2014, Pages 1331-1341

Trop2 gene: A novel target for cervical cancer treatment

Author keywords

Apoptosis; Cervical cancer; Proliferation; RNAi; Trop2

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; CYCLIN D1; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; SHORT HAIRPIN RNA;

EID: 84904365036     PISSN: 01715216     EISSN: 14321335     Source Type: Journal    
DOI: 10.1007/s00432-014-1696-1     Document Type: Article
Times cited : (14)

References (51)
  • 3
    • 84896543730 scopus 로고    scopus 로고
    • Pharmacist authority to provide HPV vaccine: Novel partners in cervical cancer prevention
    • Brewer NT, Chung JK, Baker HM, Rothholz MC, Smith JS (2014) Pharmacist authority to provide HPV vaccine: novel partners in cervical cancer prevention. Gynecol Oncol 132(Suppl 1):S3-S8
    • (2014) Gynecol Oncol , vol.132 , Issue.SUPPL. 1
    • Brewer, N.T.1    Chung, J.K.2    Baker, H.M.3    Rothholz, M.C.4    Smith, J.S.5
  • 4
    • 0035045052 scopus 로고    scopus 로고
    • Assignment of TACSTD1 (alias TROP1, M4S1) to human chromosome 2p21 and refinement of mapping of TACSTD2 (alias TROP2, M1S1) to human chromosome 1p32 by in situ hybridization
    • Calabrese G, Crescenzi C, Morizio E, Palka G, Guerra E, Alberti S (2001) Assignment of TACSTD1 (alias TROP1, M4S1) to human chromosome 2p21 and refinement of mapping of TACSTD2 (alias TROP2, M1S1) to human chromosome 1p32 by in situ hybridization. Cytogenet Cell Genet 92(1-2):164-165 (Pubitemid 32304683)
    • (2001) Cytogenetics and Cell Genetics , vol.92 , Issue.1-2 , pp. 164-165
    • Calabrese, G.1    Crescenzi, C.2    Morizio, E.3    Palka, G.4    Guerra, E.5    Alberti, S.6
  • 5
    • 77955480479 scopus 로고    scopus 로고
    • Ranpirnase (Frog RNase) targeted with a humanized, internalizing, anti-Trop-2 antibody has potent cytotoxicity against diverse epithelial cancer cells
    • Chang CH, Gupta P, Michel R, Loo M, Wang Y, Cardillo TM, Goldenberg DM (2010) Ranpirnase (Frog RNase) targeted with a humanized, internalizing, anti-Trop-2 antibody has potent cytotoxicity against diverse epithelial cancer cells. Mol Cancer Ther 9(8):2276-2286
    • (2010) Mol Cancer Ther , vol.9 , Issue.8 , pp. 2276-2286
    • Chang, C.H.1    Gupta, P.2    Michel, R.3    Loo, M.4    Wang, Y.5    Cardillo, T.M.6    Goldenberg, D.M.7
  • 7
    • 70349175559 scopus 로고    scopus 로고
    • Trop2: A possible therapeutic target for late stage epithelial carcinomas
    • Cubas R, Li M, Chen C, Yao Q (2009) Trop2: a possible therapeutic target for late stage epithelial carcinomas. Biochim Biophys Acta 1796(2):309-314
    • (2009) Biochim Biophys Acta , vol.1796 , Issue.2 , pp. 309-314
    • Cubas, R.1    Li, M.2    Chen, C.3    Yao, Q.4
  • 8
    • 84904356042 scopus 로고    scopus 로고
    • Cervical cancer screening: On the way to a shift from cytology to full molecular screening
    • Dijkstra MG, Snijders PJ, Arbyn M, Rijkaart DC, Berkhof J, Meijer CJ (2014) Cervical cancer screening: on the way to a shift from cytology to full molecular screening. Ann Oncol 25(5):927-935
    • (2014) Ann Oncol , vol.25 , Issue.5 , pp. 927-935
    • Dijkstra, M.G.1    Snijders, P.J.2    Arbyn, M.3    Rijkaart, D.C.4    Berkhof, J.5    Meijer, C.J.6
  • 9
    • 27444444495 scopus 로고    scopus 로고
    • E-cadherin and β-catenin expression in early stage cervical carcinoma: A tissue microarray study of 147 cases
    • Fadare O, Reddy H, Wang J, Hileeto D, Schwartz PE, Zheng W (2005) E-cadherin and β-catenin expression in early stage cervical carcinoma: a tissue microarray study of 147 cases. World J Surg Oncol 3:38-48
    • (2005) World J Surg Oncol , vol.3 , pp. 38-48
    • Fadare, O.1    Reddy, H.2    Wang, J.3    Hileeto, D.4    Schwartz, P.E.5    Zheng, W.6
  • 10
    • 0019782116 scopus 로고
    • Human papillomavirus (HPV) in condylomatous lesions of cervix
    • Ferenczy A, Braun L, Shah KV (1981) Human papillomavirus (HPV) in condylomatous lesions of cervix. Am J Surg Pathol 5(7):661-670
    • (1981) Am J Surg Pathol , vol.5 , Issue.7 , pp. 661-670
    • Ferenczy, A.1    Braun, L.2    Shah, K.V.3
  • 14
    • 17044411344 scopus 로고    scopus 로고
    • A virus-based vaccine may prevent cervical cancer
    • Gravitt PE, Shah KV (2005) A virus-based vaccine may prevent cervical cancer. Curr Infect Dis Rep 7(2):125-131
    • (2005) Curr Infect Dis Rep , vol.7 , Issue.2 , pp. 125-131
    • Gravitt, P.E.1    Shah, K.V.2
  • 17
    • 84888061679 scopus 로고    scopus 로고
    • Population impact of HPV vaccines: Summary of early evidence
    • Hariri S, Markowitz LE, Dunne EF, Unger ER (2013) Population impact of HPV vaccines: summary of early evidence. J Adolesc Health 53(6):679-682
    • (2013) J Adolesc Health , vol.53 , Issue.6 , pp. 679-682
    • Hariri, S.1    Markowitz, L.E.2    Dunne, E.F.3    Unger, E.R.4
  • 18
    • 0027033494 scopus 로고
    • Characterization of HPV-16 E6/E7 transcription in CaSki cells by quantitative PCR
    • Hsu EM, McNicol PJ (1992) Characterization of HPV-16 E6/E7 transcription in CaSki cells by quantitative PCR. Mol Cell Probes 6(6):459-466
    • (1992) Mol Cell Probes , vol.6 , Issue.6 , pp. 459-466
    • Hsu, E.M.1    McNicol, P.J.2
  • 19
    • 0022466496 scopus 로고
    • Production of tumor-associated antigen, TA-4, by the CaSki cervical carcinoma cell line
    • Hussa RO, Maruo T, Strobel JL, Pattillo RA, Mochizuki M (1986) Production of tumor-associated antigen, TA-4, by the CaSki cervical carcinoma cell line. Obstet Gynecol 67(6):802-805 (Pubitemid 16060041)
    • (1986) Obstetrics and Gynecology , vol.67 , Issue.6 , pp. 802-805
    • Hussa, R.O.1    Maruo, T.2    Strobel, J.L.3
  • 20
    • 0028169371 scopus 로고
    • PRAD-1/cyclinD1 gene amplification correlates with messenger RNA over-expression and tumor progression in human laryngeal carcinomas
    • Jares P, Pl Fernandez, Campo E, Nadal A, Bosch F, Aiza G, Nayach I, Traserra J, Cardesa A (1994) PRAD-1/cyclinD1 gene amplification correlates with messenger RNA over-expression and tumor progression in human laryngeal carcinomas. Cancer Res 54(17):4813-4817
    • (1994) Cancer Res , vol.54 , Issue.17 , pp. 4813-4817
    • Jares, P.1    Fernandez, P.2    Campo, E.3    Nadal, A.4    Bosch, F.5    Aiza, G.6    Nayach, I.7    Traserra, J.8    Cardesa, A.9
  • 21
    • 39749154101 scopus 로고    scopus 로고
    • Identification of Trop-2 as an oncogene and an attractive therapeutic target in colon cancers
    • DOI 10.1158/1535-7163.MCT-07-2003
    • Jianbo W, Ryan D, Yiyu D, Weintraub SJ, Michel L (2008) Identification of Trop-2 as an oncogene and an attractive therapeutic target in colon cancers. Mol Cancer Ther 7(2):280-285 (Pubitemid 351302522)
    • (2008) Molecular Cancer Therapeutics , vol.7 , Issue.2 , pp. 280-285
    • Wang, J.1    Day, R.2    Dong, Y.3    Weintraub, S.J.4    Michel, L.5
  • 22
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: A primary site for Bcl- 2 regulation of apoptosis
    • DOI 10.1126/science.275.5303.1132
    • Kluck RM, Bossy-Wetzel E, Green DR, Newmeyer DD (1997) The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 275(5303):1132-1136 (Pubitemid 27097313)
    • (1997) Science , vol.275 , Issue.5303 , pp. 1132-1136
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3    Newmeyer, D.D.4
  • 23
    • 0032568954 scopus 로고    scopus 로고
    • Apoptosis induction by caspase-8 is amplified through the mitochondrial release of cytochrome c
    • DOI 10.1074/jbc.273.26.16589
    • Kuwana T, Smith JJ, Muzio M, Dixit V, Newmeyer DD, Kornbluth S (1998) Apoptosis induction by caspase-8 is amplified through the mitochondrial release of cytochrome c. J Biol Chem 273(26):16589-16594 (Pubitemid 28311447)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.26 , pp. 16589-16594
    • Kuwana, T.1    Smith, J.J.2    Muzio, M.3    Dixit, V.4    Newmeyer, D.D.5    Kornbluth, S.6
  • 24
    • 41649104377 scopus 로고    scopus 로고
    • CIAPIN1 inhibits gastric cancer cell proliferation and cell cycle progression by downregulating cyclinD1 and upregulating P27
    • Li X, Hao Z, Fan R, Zou X, Jin H, Pan Y, He L, Du R, Gao L, Liu D, Fan D (2007) CIAPIN1 inhibits gastric cancer cell proliferation and cell cycle progression by downregulating CyclinD1 and upregulating P27. Cancer Biol Ther 6(10):1539-1545 (Pubitemid 351590324)
    • (2007) Cancer Biology and Therapy , vol.6 , Issue.10 , pp. 1539-1545
    • Li, X.1    Hao, Z.2    Fan, R.3    Zou, X.4    Jin, H.5    Pan, Y.6    He, L.7    Du, R.8    Gao, L.9    Liu, J.10    Fan, D.11
  • 25
    • 0025641163 scopus 로고
    • Human papillomavirus: A sexually transmitted disease with carcinogenic potential
    • Lilley L, Schaffer S (1990) Human papillomavirus: a sexually transmitted disease with carcinogenic potential. Cancer Nurs 13(6):366-372
    • (1990) Cancer Nurs , vol.13 , Issue.6 , pp. 366-372
    • Lilley, L.1    Schaffer, S.2
  • 26
    • 0026582174 scopus 로고
    • Localization of HPV-16 DNA sequence in CaSki cells by electron microscopic hybridocytochemistry
    • Lin CT, Chen CC, How SW, Huang WM, Peck K (1992) Localization of HPV-16 DNA sequence in CaSki cells by electron microscopic hybridocytochemistry. J Histochem Cytochem 40(4):467-473
    • (1992) J Histochem Cytochem , vol.40 , Issue.4 , pp. 467-473
    • Lin, C.T.1    Chen, C.C.2    How, S.W.3    Huang, W.M.4    Peck, K.5
  • 28
    • 84884699199 scopus 로고    scopus 로고
    • Overexpression of TROP2 predicts poor prognosis of patients with cervical cancer and promotes the proliferation and invasion of cervical cancer cells by regulating ERK signaling pathway
    • Liu T, Liu Y, Bao X, Tian J, Liu Y, Yang X (2013) Overexpression of TROP2 predicts poor prognosis of patients with cervical cancer and promotes the proliferation and invasion of cervical cancer cells by regulating ERK signaling pathway. PLoS One 8(9):e75864
    • (2013) PLoS One , vol.8 , Issue.9
    • Liu, T.1    Liu, Y.2    Bao, X.3    Tian, J.4    Liu, Y.5    Yang, X.6
  • 29
    • 84899086697 scopus 로고    scopus 로고
    • Activation of the EGFR/Akt/NF-κB/cyclinD1 survival signaling pathway in human cholesteatoma epithelium
    • Liu W, Yin T, Ren J, Li L, Xiao Z, Chen X, Xie D (2014) Activation of the EGFR/Akt/NF-κB/cyclinD1 survival signaling pathway in human cholesteatoma epithelium. Eur Arch Otorhinolaryngol 271(2):265-273
    • (2014) Eur Arch Otorhinolaryngol , vol.271 , Issue.2 , pp. 265-273
    • Liu, W.1    Yin, T.2    Ren, J.3    Li, L.4    Xiao, Z.5    Chen, X.6    Xie, D.7
  • 30
    • 14244251990 scopus 로고    scopus 로고
    • Vaccination strategies for the prevention of cervical cancer
    • DOI 10.1586/14737140.5.1.xxx
    • Maclean J, Rybicki EP, Williamson AL (2005) Vaccination strategies for the prevention of cervical cancer. Expert Rev Anticancer Ther 5(1):97-107 (Pubitemid 40287440)
    • (2005) Expert Review of Anticancer Therapy , vol.5 , Issue.1 , pp. 97-107
    • Maclean, J.1    Rybicki, E.P.2    Williamson, A.-L.3
  • 32
    • 33744800782 scopus 로고    scopus 로고
    • Clinical significance of TROP2 expression in colorectal cancer
    • DOI 10.1158/1078-0432.CCR-05-1961
    • Ohmachi T, Tanaka F, Mimori K, Inoue H, Yanaga K, Mori M (2006) Clinical significance of TROP2 expression in colorectal cancer. Clin Cancer Res 12(10):3057-3063 (Pubitemid 43837351)
    • (2006) Clinical Cancer Research , vol.12 , Issue.10 , pp. 3057-3063
    • Ohmachi, T.1    Tanaka, F.2    Mimori, K.3    Inoue, H.4    Yanaga, K.5    Mori, M.6
  • 33
    • 0027717104 scopus 로고
    • Human papillomavirus type 16 E6, E7 and L1 and type 18 E7 proteins produced by recombinant baculoviruses
    • Park DS, Selvey LA, Kelsall SR, Frazer IH (1993) Human papillomavirus type 16 E6, E7 and L1 and type 18 E7 proteins produced by recombinant baculoviruses. J Virol Methods 45(3):303-318
    • (1993) J Virol Methods , vol.45 , Issue.3 , pp. 303-318
    • Park, D.S.1    Selvey, L.A.2    Kelsall, S.R.3    Frazer, I.H.4
  • 34
    • 0017641967 scopus 로고
    • Tumor antigen and human chorionic gonadotropin in CaSki cells: A new epidermoid cervical cancer cell line
    • Pattillo RA, Hussa RO, Story MT, Ruckert AC, Shalaby MR, Mattingly RF (1977) Tumor antigen and human chorionic gonadotropin in CaSki cells: a new epidermoid cervical cancer cell line. Science 196(4297):1456-1458 (Pubitemid 8122337)
    • (1977) Science , vol.196 , Issue.4297 , pp. 1456-1458
    • Patillo, R.A.1    Hussa, R.O.2    Story, M.T.3
  • 37
    • 0029858891 scopus 로고    scopus 로고
    • Structure-function analysis of Bcl-2 family proteins: Regulators of programmed cell death
    • Reed JC, Zha H, Aime-Sempe C, Takayama S, Wang HG (1996) Structure-function analysis of Bcl-2 family proteins: regulators of programmed cell death. Adv Exp Med Biol 406:99-112
    • (1996) Adv Exp Med Biol , vol.406 , pp. 99-112
    • Reed, J.C.1    Zha, H.2    Aime-Sempe, C.3    Takayama, S.4    Wang, H.G.5
  • 38
    • 0034737818 scopus 로고    scopus 로고
    • Molecular biology: RNA interference
    • Sharp PA, Zamore PD (2000) Molecular biology: RNA interference. Science 287(5462):2431-2433
    • (2000) Science , vol.287 , Issue.5462 , pp. 2431-2433
    • Sharp, P.A.1    Zamore, P.D.2
  • 39
    • 0034958237 scopus 로고    scopus 로고
    • p53-dependent apoptosis pathways
    • DOI 10.1016/S0065-230X(01)82002-9
    • Shen Y, White E (2001) p53-dependent apoptosis pathways. Adv Cancer Res 82:55-84 (Pubitemid 32613382)
    • (2001) Advances in Cancer Research , vol.82 , pp. 55-84
    • Shen, Y.1    White, E.2
  • 41
    • 80051733033 scopus 로고    scopus 로고
    • Expression of Trop2 cell surface glycoprotein in normal and tumor tissues: Potential implications as a cancer therapeutic target
    • Stepan LP, Trueblood ES, Hale K, Babcook J, Borges L, Sutherland CL (2011) Expression of Trop2 cell surface glycoprotein in normal and tumor tissues: potential implications as a cancer therapeutic target. J Histochem Cytochem 59(7):701-710
    • (2011) J Histochem Cytochem , vol.59 , Issue.7 , pp. 701-710
    • Stepan, L.P.1    Trueblood, E.S.2    Hale, K.3    Babcook, J.4    Borges, L.5    Sutherland, C.L.6
  • 42
    • 84867702118 scopus 로고    scopus 로고
    • Regulated proteolysis of Trop2 drives epithelial hyperplasia and stem cell self-renewal viat β-catenin signaling
    • Stoyanova T, Goldstein AS, Cai H, Drake JM, Huang J, Witte ON (2012) Regulated proteolysis of Trop2 drives epithelial hyperplasia and stem cell self-renewal viat β-catenin signaling. Genes Dev 26(20):2271-2285
    • (2012) Genes Dev , vol.26 , Issue.20 , pp. 2271-2285
    • Stoyanova, T.1    Goldstein, A.S.2    Cai, H.3    Drake, J.M.4    Huang, J.5    Witte, O.N.6
  • 43
    • 0021843944 scopus 로고
    • Human papilloma virus (HPV) infections related to cervical intraepithelial neoplasia (CIN) and squamous cell carcinoma of the uterine cervix
    • Syrjänen KJ, Syrjänen SM (1985) Human papilloma virus (HPV) infections related to cervical intraepithelial neoplasia (CIN) and squamous cell carcinoma of the uterine cervix. Ann Clin Res 2:45-56
    • (1985) Ann Clin Res , vol.2 , pp. 45-56
    • Syrjänen, K.J.1    Syrjänen, S.M.2
  • 44
    • 0033119801 scopus 로고    scopus 로고
    • beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
    • DOI 10.1038/18884
    • Tetsu O, McCormick F (1999) Beta-catenin regulates expression of cyclinD1 in colon carcinoma cells. Nature 398(6726):422-426 (Pubitemid 29180374)
    • (1999) Nature , vol.398 , Issue.6726 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 46
    • 84877850441 scopus 로고    scopus 로고
    • Trop-2 promotes prostate cancer metastasis by modulating β(1) integrin functions
    • Trerotola M, Jernigan DL, Liu Q, Siddiqui J, Fatatis A, Languino LR (2013b) Trop-2 promotes prostate cancer metastasis by modulating β(1) integrin functions. Cancer Res 73(10):3155-3167
    • (2013) Cancer Res , vol.73 , Issue.10 , pp. 3155-3167
    • Trerotola, M.1    Jernigan, D.L.2    Liu, Q.3    Siddiqui, J.4    Fatatis, A.5    Languino, L.R.6
  • 47
    • 84893061405 scopus 로고    scopus 로고
    • Second-generation prophylactic HPV vaccines: Successes and challenges
    • Tyler M, Tumban E, Chackerian B (2014) Second-generation prophylactic HPV vaccines: successes and challenges. Expert Rev Vaccines 13(2):247-255
    • (2014) Expert Rev Vaccines , vol.13 , Issue.2 , pp. 247-255
    • Tyler, M.1    Tumban, E.2    Chackerian, B.3
  • 51
    • 0031036872 scopus 로고    scopus 로고
    • Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
    • DOI 10.1126/science.275.5303.1129
    • Yang J, Liu X, Bhalla K, Kim CN, Ibrado AM, Cai J, Peng TI, Jones DP, Wang X (1997) Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science 275(5303):1129-1132 (Pubitemid 27097312)
    • (1997) Science , vol.275 , Issue.5303 , pp. 1129-1132
    • Yang, J.1    Liu, X.2    Bhalla, K.3    Kim, C.N.4    Ibrado, A.M.5    Cai, J.6    Peng, T.-I.7    Jones, D.P.8    Wang, X.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.