TRIM38 Negatively Regulates TLR3-Mediated IFN-β Signaling by Targeting TRIF for Degradation

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Xue, Qinghua ^a   Zhou, Zhuo ^a   Lei, Xiaobo ^a   Liu, Xinlei ^a   He, Bin ^b   Wang, Jianwei ^a   Hung, Tao ^a  

^a INSTITUTE OF PATHOGEN BIOLOGY   (China)

^b UNIVERSITY OF ILLINOIS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BETA INTERFERON; INTERFERON; PROTEIN; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; TRIPARTITE MOTIF PROTEIN 38; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION; UBIQUITINATION;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; CARRIER PROTEINS; GENE KNOCKDOWN TECHNIQUES; HEK293 CELLS; HELA CELLS; HUMANS; IMMUNITY, INNATE; INTERFERON-BETA; LYSINE; POLYUBIQUITIN; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEOLYSIS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 3; UBIQUITINATION;

EID: 84867308377     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0046825     Document Type: Article

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