Role of the C-sheet in the maturation of N-glycans on antithrombin: Functional relevance of pleiotropic mutations

Journal of Thrombosis and Haemostasis

Volumn 12, Issue 7, 2014, Pages 1131-1140

  Aguila S ^a   Navarro Fernandez J ^a   Bohdan, N ^a   Gutierrez Gallego R ^b,c   de la Morena Barrio, M E ^a   Vicente, V ^a   Corral, J ^a   Martinez Martinez I ^a  

^a UNIVERSITY OF MURCIA   (Spain)

^b UNIVERSITAT POMPEU FABRA   (Spain)

^c Protein and Peptide Chemistry Anapharm Biotech   (Spain)

Author keywords

Antithrombin III; Antithrombin III deficiency; Glycosylation; Isolation purification; Recombinant proteins

Indexed keywords

ANTITHROMBIN; BETA ACTIN; BLOOD CLOTTING FACTOR 10A; GLYCAN; HEPARIN; LEUKOCYTE ELASTASE; PROTEINASE; THROMBIN; POLYSACCHARIDE; RECOMBINANT PROTEIN;

ANTITHROMBIN DEFICIENCY; ARTICLE; CONTROLLED STUDY; ELECTROPHORESIS; ELECTROPHORETIC MOBILITY; FLUORESCENCE ANALYSIS; GLYCOSYLATION; HUMAN; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MUTATION; PLEIOTROPY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN PURIFICATION; PROTEOMICS; SITE DIRECTED MUTAGENESIS; WILD TYPE; ADOLESCENT; ADULT; ANTITHROMBIN III DEFICIENCY; CHEMISTRY; GENETICS; HETEROZYGOTE; MASS SPECTROMETRY; METABOLISM; MIDDLE AGED; PROGNOSIS; PROTEIN TERTIARY STRUCTURE; THROMBOSIS;

ADOLESCENT; ADULT; ANTITHROMBIN III DEFICIENCY; ANTITHROMBINS; ELECTROPHORESIS; GLYCOSYLATION; HEPARIN; HETEROZYGOTE; HUMANS; LEUKOCYTE ELASTASE; MIDDLE AGED; MUTAGENESIS, SITE-DIRECTED; MUTATION; POLYSACCHARIDES; PROGNOSIS; PROTEIN STRUCTURE, TERTIARY; PROTEOMICS; RECOMBINANT PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; THROMBIN; THROMBOSIS;

EID: 84904324496     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/jth.12606     Document Type: Article

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